Peer reviewed publications (since establishment of the group at the DKFZ in 2012)


Taylor F  and Fischer A. (2019) Endothelial cells dictate cardiac fuelsource. AGING 2019, Vol. 11, Advance


Tetzlaff F and Fischer A. (2018) Human Endothelial Cell Spheroid-based Sprouting Angiogenesis Assay in Collagen. BioProtocol. Sep 05. Vol 8 (17).

Klose R, Adam MG, Weis EM, Moll I, Wüstehube-Lausch J, Tetzlaff F, Oka C, Ehrmann M, Fischer A. (2018) Inactivation of the serine protease HTRA1 inhibits tumor growth by deregulating angiogenesis. Oncogene. Aug;37(31):4260-4272.

Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma TP, Herberich SE, Sauer SW, Poschet G, Federico G, Mogler C, Weis EM, Augustin HG, Yan M, Gretz N, Schmid RM, Adams RH, Gröne HJ, Hell R, Okun JG, Backs J, Nawroth PP, Herzig S, Fischer A. (2018) Inhibition of endothelial Notch signaling impairs fatty acid transport and leads to metabolic and vascular remodeling of the adult heart. Circulation. Jun 12;137(24):2592-2608.

Editorial in Circulation.

Tetzlaff F, Adam MG, Feldner A, Moll I, Menuchin A, Rodriguez-Vita J, Sprinzak D, Fischer A. (2018) MPDZ promotes DLL4-induced Notch signaling during angiogenesis. eLife. Apr 5;7. pii: e32860.


Tetzlaff F and Fischer A. (2018) Control of blood vessel formation by Notch signaling. Advances in Experimental Medicine and Biology. 1066:319-338.


Fischer A and Braga V.M.M. (2018) Vascular Permeability: Flow-Mediated, Non-canonical Notch Signalling Promotes Barrier Integrity. Current Biol. Feb 5;28(3):R119-R121.


Fischer A and Nawroth PP (2018). Chapters 31, 33, 42,47 and 54 in Kihm L, Kopf S, Nawroth PP (Ed.), Diabetes-Therapie – informiert entscheiden. Patientenzentriertes und fallbasiertes Vorgehen über Leitlinien hinaus. Springer. Berlin Heidelberg.  


Feldner A, Adam MG, Tetzlaff F, Moll I, Komljenovic D, Sahm F, Bäuerle T, Ishikawa H, Schroten H, Korff T, Hofmann I, Wolburg H, von Deimling A, Fischer A. (2017) Loss of Mpdz impairs ependymal cell integrity leading to perinatal-onset hydrocephalus in mice. EMBO Mol Med. Jul;9(7):890-905.

Wieland E*, Rodriguez-Vita J*, Liebler SS, Mogler C, Moll I, Herberich SE, Espinet E, Herpel E, Menuchin A, Chang-Claude J, Hoffmeister M, Gebhardt C, Brenner H, Trumpp A, Siebel CW, Hecker M, Utikal J, Sprinzak D, Fischer A. (2017) Endothelial Notch1 Activity Facilitates Metastasis. Cancer Cell. Mar 13;31(3):355-367.

Editorial in Cancer Cell.

Editorial in Cancer Discovery.

Comment in Science.


Rodriguez Vita JTetzlaff FFischer A (2017) Notch controls endothelial cells. Oncoscience. Jun 25;4(5-6):45-46.


Rodriguez Vita JFischer A (2017) Notch1 induces endothelial senescence and promotes tumor progression. Cell Cycle. May 19;16(10):911-912.


Rodriguez Vita JFischer A (2017) Notch signaling facilitates crossing of endothelial barriers by tumor cells. Mol Cell Oncol. Apr 3;4(3):e1311828.



Spiegler S, Kirchmaier B, Rath M, Korenke GC, Tetzlaff F, van de Vorst M, Neveling K, Acker-Palmer A, Kuss AW, Gilissen C, Fischer A, Schulte-Merker S, Felbor U. (2016) FAM222B is not a likely novel candidate gene for cerebral cavernous malformations. Mol Syndrom. Jul;7(3):144-52.


Herberich SE*, Klose R*, Moll I, Yang W-J, Wüstehube-Lausch J, Fischer A (2015) ANKS1B interacts with the cerebral cavernous malformation protein-1 and controls endothelial permeability but not sprouting angiogenesis. PLoS One.10(12):e0145304.

Yang W-J*, Hu J*, Uemura A, Tetzlaff F, Augustin HG, Fischer A (2015) Semaphorin-3C signals through Neuropilin-1 and PlexinD1 receptors to inhibit pathological angiogenesis. EMBO Mol Med. 7 (10):1267-1284.

Editorial in EMBO Mol Med.

Selected as Cover Image.


Fischer A. Physiologie Band 6, Herz und Kreislauf, 7. Auflage, MEDI-LEARN Verlag, Marburg.

Klose R*, Berger C*, Moll I, Adam MG, Schwarz F, Mohr K, Augustin HG, Fischer A (2015) Soluble Notch ligand and receptor peptides act antagonistically during angiogenesis. Cardiovasc Res. 107(1):153-163.

Wöltje K*, Jabs M*, Fischer A (2015) Serum induces transcription of Hey1 and Hey2 genes by Alk1 but not Notch signaling in endothelial cells. PLoS One. 10 (3): e0120547.

Schulz GB, Wieland E, Wüstehube-Lausch J, Boulday G, Moll I, Tournier-Lasserve E, Fischer A (2015) Cerebral cavernous malformation-1 protein controls DLL4-Notch3 signaling between the endothelium and pericytes. Stroke. 46(5):1337-1343.


Adam MGBerger C, Feldner A, Yang W-J, Wüstehube-Lausch J, Herberich SE, Pinder M, Gesierich S, Hammes H-P, Augustin HG, Fischer A (2013) Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis. Circ Res. 113: 1206-1218.

Editorial in Circ Res.

Selected as Cover Image.

Among the 10 most read articles published 2013 in Circ Res.

Schaafhausen MK, Yang WJ, Centanin L, Wittbrodt J, Bosserhoff A, Fischer A, Schartl M, Meierjohann S (2013) Tumor angiogenesis is caused by single melanoma cells in a reactive oxygen species and NF-κB dependent manner. J Cell Sci. 126: 3862-3872.


Fischer A, Zalvide J, Faurobert E, Albiges-Rizo C, Tournier-Lasserve E (2013) Cerebral cavernous malformations: from CCM genes to endothelial cell homeostasis. Trends Mol Med 19 (13): 302-308.


Liebler SSFeldner A, Adam MG, Korff T, Augustin HG, Fischer A (2012) No evidence for a functional role of bi-directional Notch signaling during angiogenesis. PLoS One. 7 (12): e53074.

group members are underlined

*, equal contribution


Publications (before establishment of DKFZ group in 2012)

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