For full list of publications see PubMed

Original articles:

Reiss S, Rebhan I, Backes P, Romero-Brey I, Erfle H, Matula P, Kaderali L, Poenisch M, Blankenburg H, Hiet MS, Longerich T, Diehl S, Ramirez F, Balla T, Rohr K, Kaul A, Bühler S, Pepperkok R, Lengauer T, Albrecht M, Eils R, Schirmacher P, Lohmann V, Bartenschlager R. 2011. Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. Cell Host Microbe. 9:32-45.

Long G, Hiet MS, Windisch MP, Lee JY, Lohmann V, Bartenschlager R. 2011. Mouse hepatic cells support assembly of infectious hepatitis C virus particles. Gastroenterology 141:1057-66.

Bauhofer O, Ruggieri A, Schmid B, Schirmacher P, Bartenschlager R. 2012. Persistance of HCV in Quiescent Hepatic Cells during an Interferon-Induced Antiviral Response. Gastroenterology. 143:429-38

Metz P, Dazert E, Ruggieri A, Mazur J, Kaderali L, Kaul A, Zeuge U, Trippler M, Lohmann V, Binder M, Frese M, Bartenschlager R. 2012. Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication. Hepatology. 56:2082-93

Pichlmair A, Kandasamy K, Alvisi G, Mulhern O, Sacco R, Habjan M, Binder M, Stefanovic A, Eberle CA, Goncalves A, Bürckstümmer T, Müller AC, Fauster A, Holze C, Lindsten K, Goodbourn S, Kochs G, Weber F, Bartenschlager R, Bowie AG, Bennett KL, Colinge J, Superti-Furga G. 2012. Viral immune modulators perturb the human molecular network by common and unique strategies. Nature. 487:486-90.

Ruggieri A, Dazert E, Metz P, Hofmann S, Bergeest JP, Mazur J, Bankhead P, Hiet MS, Kallis S, Alvisi G, Samuel CE, Lohmann V, Kaderali L, Rohr K, Frese M, Stoecklin G, Bartenschlager R. 2012. Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection. Cell Host Microbe. 12:71-85.

Romero-Brey I, Merz A, Chiramel A, Lee JY, Chlanda P, Haselman U, Santarella-Mellwig R, Habermann A, Hoppe S, Kallis S, Walther P, Antony C, Krijnse-Locker J, Bartenschlager R. 2012. Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication. PLoS Pathog. 8(12):e1003056.

Hiet MS, Bauhofer O, Zayas M, Roth H, Tanaka Y, Schirmacher P, Willemsen J, Grünvogel O, Bender S, Binder M, Lohmann V, Lotteau V, Ruggieri A, Bartenschlager R. 2015. Control of temporal activation of hepatitis C virus-induced interferon response by domain 2 of nonstructural protein 5A. J Hepatol. 2015 Apr 20. pii: S0168-8278(15)00298-6.

Lempp FA, Mutz P, Lipps C, Wirth D, Bartenschlager R, Urban S. 2015. Evidence that hepatitis B virus replication in mouse cells is limited by the lack of a host cell dependency factor. J Hepatol. Nov 11. pii: S0168-8278(15)00736-9.

Bender S, Reuter A, Eberle F, Einhorn E, Binder M, Bartenschlager R. 2015. Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus. PLoS Pathog. Nov 20;11(11):e1005264.

Seitz S, Iancu C, Volz T, Mier W, Dandri M, Urban S, Bartenschlager R. 2016. A slow maturation process renders hepatitis B virus infectious. Cell Host & Microbe, 20(1):25-35. doi: 10.1016/j.chom.2016.05.013

Senís E, Mockenhaupt S, Rupp D, Bauer T, Paramasivam N, Knapp B, Gronych J, Grosse S, Windisch MP, Schmidt F, Theis FJ, Eils R, Lichter P, Schlesner M, Bartenschlager R, Grimm D. 2016. TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus. Nucleic Acids Res. 2016 Sep 9. pii: gkw805. [Epub ahead of print].

Lauber C, Seitz S, Mattei S, Suh A, Beck J, Herstein J, Börold J, Salzburger W, Kaderali L, Briggs JAG, Bartenschlager R. 2017. Deciphering the Origin and Evolution of Hepatitis B Viruses by Means of a Family of Non-enveloped Fish Viruses. Cell Host Microbe, 22(3):387-399.e6. doi: 10.1016/j.chom.2017.07.019.

Levander S, Holmström F, Frelin L, Ahlén G, Rupp D, Long G, Bartenschlager R*, Sällberg M*. 2017. Immune-mediated effects targeting hepatitis C virus in a syngeneic replicon cell transplantation mouse model. Gut, gutjnl-2016-313579. *co-correspondance

Selected reviews:

Bühler S, Bartenschlager R. 2012. Promotion of hepatocellular carcinoma by hepatitis C virus. Dig Dis. 2012;30(5):445-52.

Bartenschlager, R. (Editor) 2013. Hepatitis C Virus: From Molecular Virology to Antiviral Therapy. Series: Current Topics in Microbiology and Immunology, Vol. 369.

Urban S, Bartenschlager R, Kubitz R, Zoulim F. 2014. Strategies to Inhibit Entry of HBV and HDV Into Hepatocytes. Gastroenterology. 147:48-64.

Paul D, Madan V, Bartenschlager R. 2014. Hepatitis C Virus RNA Replication and Assembly: Living on the Fat of the Land. Cell Host & Microbe 16:569-579.

Bartenschlager RF, Rice CM, Sofia MJ. 2016. Hepatitis C Virus-From Discovery to Cure: The 2016 Lasker-DeBakey Clinical Medical Research Award. JAMA. 2016 Sep 27;316(12):1254-5. doi: 10.1001/jama.2016.13713.

Kaufmann SHE, Dorhoi A, Hotchkiss RS, Bartenschlager R. 2017. Host-directed therapies for bacterial and viral infections. Nat Rev Drug Discov., doi: 10.1038/nrd.2017.162.

Tu T, Bühler S, Bartenschlager R. 2017. Chronic viral hepatitis and its association with liver cancer. Biol Chem. 398(8):817-837.

to top