Publications

Hasche D, Akgül B. Role of human papillomavirus (HPV) in the development of skin cancer [Article in German]. Hautarzt. 2022 Jun;73(6):417-425. doi: 10.1007/s00105-022-04990-x. Review.

Hasche D, Ahmels M, Braspenning-Wesch I, Stephan S, Cao R, Schmidt G, Müller M, Rösl F. Isoforms of the Papillomavirus Major Capsid Protein Differ in Their Ability to Block Viral Spread and Tumor Formation. Front Immunol. 2022 Mar 14;13:811094. doi: 10.3389/fimmu.2022.811094.

Lambert PF, Münger K, Rösl F, Hasche D, Tommasino M. Beta human papillomaviruses and skin cancer. Nature. 2020 Dec;588(7838):E20-E21. doi: 10.1038/s41586-020-3023-0.

Zhuang L, Ly R, Rösl F, Niebler M. p53 Is Regulated in a Biphasic Manner in Hypoxic Human Papillomavirus Type 16 (HPV16)-Positive Cervical Cancer Cells. Int J Mol Sci. 2020 Dec 15;21(24):9533. doi: 10.3390/ijms21249533.

Fu Y, Cao R, Schäfer M, Stephan S, Braspenning-Wesch I, Schmitt L, Bischoff R, Müller M, Schäfer K, Vinzón SE, Rösl F, Hasche D. Expression of different L1 isoforms of Mastomys natalensis papillomavirus as mechanism to circumvent adaptive immunity. Elife. 2020 Aug 4;9:e57626. doi: 10.7554/eLife.57626.

Yang R, Klimentová J, Göckel-Krzikalla E, Ly R, Gmelin N, Hotz-Wagenblatt A, Řehulková H, Stulík J, Rösl F, Niebler M. (2019). Combined Transcriptome and Proteome Analysis of Immortalized Human Keratinocytes Expressing Human Papillomavirus 16 (HPV16) Oncogenes Reveals Novel Key Factors and Networks in HPV-Induced Carcinogenesis. mSphere. 2019 Mar 27;4(2). pii: e00129-19. doi: 10.1128/mSphere.00129-19.

Savini C, Yang R, Savelyeva L, Göckel-Krzikalla E, Hotz-Wagenblatt A, Westermann F, Rösl F. (2019). Folate Repletion after Deficiency Induces Irreversible Genomic and Transcriptional Changes in Human Papillomavirus Type 16 (HPV16)-Immortalized Human Keratinocytes. Int J Mol Sci. 2019 Mar 4;20(5). pii: E1100. doi: 10.3390/ijms20051100.

Hasche D, Rösl F. (2019). Mastomys Species as Model Systems for Infectious Diseases. Viruses. 2019 Feb 21;11(2). pii: E182. doi: 10.3390/v11020182. Review.

Bossler F, Kuhn BJ, Günther T, Kraemer SJ, Khalkar P, Adrian S, Lohrey C, Holzer A, Shimobayashi M, Dürst M, Mayer A, Rösl F, Grundhoff A, Krijgsveld J, Hoppe-Seyler K, Hoppe-Seyler F. (2019). Repression of Human Papillomavirus Oncogene Expression under Hypoxia Is Mediated by PI3K/mTORC2/AKT Signaling. MBio. 2019 Feb 12;10(1). pii: e02323-18. doi: 10.1128/mBio.02323-18.

Kruse S, Büchler M, Uhl P, Sauter M, Scherer P, Lan TCT, Zottnick S, Klevenz A, Yang R, Rösl F, Mier W, Riemer AB. (2018) Therapeutic vaccination using minimal HPV16 epitopes in a novel MHC-humanized murine HPV tumor model. Oncoimmunology. 2018 Oct 29;8(1):e1524694. doi: 10.1080/2162402X.2018.1524694. eCollection 2019.

Hasche D, Vinzón SE, Rösl F. (2018) Cutaneous Papillomaviruses and Non-melanoma Skin Cancer: Causal Agents or Innocent Bystanders? Front Microbiol. 2018 May 2;9:874. doi: 10.3389/fmicb.2018.00874. eCollection 2018. Review.

Hasche D, Stephan S, Braspenning-Wesch I, Mikulec  J, Niebler M, Gröne H-J, Flechtenmacher C, Akgül B, Rösl F, and Vinzón SE (2017). The Interplay of UV and Cutaneous Papillomavirus Infection in Non-Melanoma Skin Cancer Development in the animal model Mastomys coucha.PLoS Pathog 13(11): e1006723. doi: 10.1371/journal.ppat.1006723.

Bach M, Savini C, Krufczik M, Cremer C, Rösl F, Hausmann M. (2017). Super-   Resolution Localization Microscopy of γ-H2AX and Heterochromatin after Folate Deficiency. Int J Mol Sci. 2017 Aug 8;18(8). pii: E1726. doi: 10.3390/ijms18081726.

Hoppe-Seyler K, Bossler F, Lohrey C, Bulkescher J, Rösl F , Jansen L, Mayer A, Vaupel P, Dürst M, Hoppe-Seyler F. (2017). Induction of Dormancy in Hypoxic Human Papillomavirus-Positive Cancer Cells. Proc. Natl. Acad. Sci. USA, 114: E990-E998

Higareda-Almaraz JC, Ruiz-Moreno JS, Klimentova J, Barbieri D, Salvador-Gallego R, Ly R, Valtierra-Gutierrez IA, Dinsart C, Rabinovich GA, Stulik J, Rösl F, Rincon-Orozco B. (2016). Systems-level effects of ectopic galectin-7 reconstitution in cervical cancer and its microenvironment. BMC Cancer. 2016 Aug 24;16:680. doi: 10.1186/s12885-016-2700-8.

Hasche D, Stephan S, Savelyeva L, Westermann F, Rösl F, Vinzón SE. (2016). Establishment of an Immortalized Skin Keratinocyte Cell Line Derived from the Animal Model Mastomys coucha. PLoS One. 2016 Aug 17;11(8):e0161283. doi: 10.1371/journal.pone.0161283. eCollection 2016.
 
Darvin ME, Thiede G, Ascencio SM, Schanzer S, Richter H, Vinzón SE, Hasche D, Rösl F, May R, Hazot Y, Tamarkin D, Lademann J. (2016). In vivo/ex vivo targeting of Langerhans cells after topical application of the immune response modifier TMX-202: confocal Raman microscopy and histology analysis. J Biomed Opt. 2016 May 31;21(5):55004. doi: 10.1117/1.JBO.21.5.055004.

Salvermoser M, Chotewutmontri S, Braspenning-Wesch I, Hasche D, Rösl F, Vinzón SE. (2016). Transcriptome analysis of Mastomys natalensis papillomavirus in productive lesions after natural infection. J Gen Virol. 2016 Jul;97(7):1658-69. doi: 10.1099/jgv.0.000471. Epub 2016 Apr 4.

Fassl A, Tagscherer KE, Richter J, De-Castro Arce J, Savini C, Rösl F, Roth W. (2015). Inhibition of Notch1 signaling overcomes resistance to the death ligand Trail by specificity protein 1-dependent upregulation of death receptor 5. Cell Death Dis. 2015 Oct 15;6:e1921. doi: 10.1038/cddis.2015.261.

Vinzón SE, Rösl F. (2015). HPV vaccination for prevention of skin cancer. Hum Vaccin Immunother. 2015;11(2):353-7. doi: 10.4161/21645515.2014.983858. Review.

Barbieri D, Venturoli S, Rösl F, Rincon-Orozco B. (2014). Detection of high-risk human papillomavirus type 16 and 18 using isothermal helicase-dependent amplification. Diagn Microbiol Infect Dis. 2014 Jun;79(2):178-82. doi: 10.1016/j.diagmicrobio.2014.02.012. Epub 2014 Feb 24

Vinzon, S.E., Braspenning-Wesch, I., Müller, M., Geissler, E.K., Nindl, I., Gröne, H-J., Schäfer, K., and Rösl, F. (2014). Protective Vaccination against Papillomavirus-Induced Skin Tumors under Immunocompetent and Immunosuppressive Conditions: A Preclinical Study Using a Natural Outbred Animal Model. PLoS Pathogens, Feb 20; 10 (2): e1003924

Niebler, M., Qian, X., Höfler, D., Kogosov, V., Kaewprag, J., Kaufmann, A.M., Ly, R., Böhmer, M., Zawatzky, R., Rösl, F., and Rincon-Orozco, B. (2013). Post-Translational Control of IL-1β via the Human Papillomavirus Type 16 E6 Oncoprotein: A Novel Mechanism of Innate Immune Escape Mediated by the E3-Ubiquitin Ligase E6-AP and p53. PLoS Pathogens, DOI: 10.1371/journal.ppat.1003536

Lützner, N., Kalbacher, H. Krones-Herzig, A., and Rösl, F. (2012). FOXO3 is a Glucocorticoid Receptor Target Gene and Regulates LKB1 and FOXO3 Expression Dependent on Intracellular Energy Levels Via a Positive Autoregulatory Feedback Loop. PLoS One. 7(7): e42166. Epub Jul 27.

Lützner N, De-Castro Arce J, Rösl F. (2012). Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors. PLoS One. 2012;7(3):e32590. doi: 10.1371/journal.pone.0032590. Epub 2012 Mar 6.

De-Castro Arce, J., Göckel-Krzikalla, E., Rösl, F. (2012). Silencing of multi-copy HPV-16 by viral self-methylation and chromatin occlusion: a model for an epigenetic virus-host interaction. Human Molecular Genetics, 21: 1693-1705.

Muschik, D., Braspenning-Wesch, I., Stockfleth, E., Rösl, F., Hofmann, T.G., and Nindl, I. (2011). Cutaneous HPV23 E6 prevents p53 phosphorylation through interaction with HIPK2. PLoS One, 6(11): e27655.

Rosenberger, S.J., De-Castro, J., Langbein, L., Steenbergen, R., and Rösl, F. (2010). Alternative splicing of HPV16 E6/E6* early mRNA is coupled to EGF-signalling via Erk activation. Proc. Natl. Acad. Sci. U.S.A., 107: 7006-7011.

Serchov, T., Dubois-Pot-Schneider, H., Charlot, C., Rösl, F., and Wasylyk, B. (2010). Involvement of Net and HIF1 in distinct yet intricately linked hypoxia induced signalling pathways. Journal of Biological Chemistry, 285: 21223-21232.