Cookie Settings

We use cookies to optimize our website. These include cookies that are necessary for the operation of the site, as well as those that are only used for anonymous statistic. You can decide for yourself which categories you want to allow. Further information can be found in our data privacy protection .


These cookies are necessary to run the core functionalities of this website and cannot be disabled.

Name Webedition CMS
Purpose This cookie is required by the CMS (Content Management System) Webedition for the system to function correctly. Typically, this cookie is deleted when the browser is closed.
Name econda
Purpose Session cookie emos_jcsid for the web analysis software econda. This runs in the “anonymized measurement” mode. There is no personal reference. As soon as the user leaves the site, tracking is ended and all data in the browser are automatically deleted.

These cookies help us understand how visitors interact with our website by collecting and analyzing information anonymously. Depending on the tool, one or more cookies are set by the provider.

Name econda
Purpose Statistics
External media

Content from external media platforms is blocked by default. If cookies from external media are accepted, access to this content no longer requires manual consent.

Name YouTube
Purpose Show YouTube content
Name Twitter
Purpose activate Twitter Feeds

Press Releases

No. 21 | 16. April 2024 | by Koh

Combination therapy can delay resistance of lung cancer cells

Lung cancer cell during division
© Bestvater / DKFZ

A specific genetic alteration, known as an ALK fusion, drives non-small cell lung cancer in some patients. This abnormality leads to excessive activity of the ALK protein, a key cancer promoter. These tumors can be treated with an ALK inhibitor - but the cancer cells quickly develop resistance to the drug. Scientists at the German Cancer Research Center have now shown in murine and human tumor cells that simultaneous treatment with ALK and SRC inhibitors improves the therapy response of the cancer cells and delays the development of resistance. The combination therapy, which strongly interferes with the protein composition of cancer cells, could improve clinical outcomes in the treatment of certain forms of non-small cell lung cancer.

read more

No. 20 | 11. April 2024 | by Koh

ERC Advanced Grants for Hannah Monyer and Michael Platten

Hannah Monyer
© Schwerdt / Universität Heidelberg

The European Research Council (ERC) supports visionary, ground-breaking research projects with its "Advanced Grants". This year, the Council awarded the prestigious funding to two researchers at the German Cancer Research Center (DKFZ): Neuroscientist Hannah Monyer, DKFZ and Heidelberg University Hospital, wants to find new explanations for the development of neurodegenerative diseases. Neurologist Michael Platten, DKFZ and University Medical Center Mannheim, will use the ERC funding to develop and test personalized cellular immunotherapies against malignant brain tumors.

read more

No. 17 | 02. April 2024 | by Koh

Precise localization of miniature robots and surgical instruments inside the body

Right: Miniature robot with built-in SMOL tracker, the built-in magnet is o...
© Qiu / DKFZ

In the medicine of the future, tiny robots will navigate independently through tissue and medical instruments will indicate their position inside the body during surgery. Both require doctors to be able to localize and control the devices precisely and in real time. Until now, there has been no suitable method for this. Scientists from the German Cancer Research Center (DKFZ) have now described a signaling method based on an oscillating magnet that can significantly improve such medical applications.

read more

No. 15 | 27. March 2024 | by Koh

The socio-economic consequences of cancer - an underestimated problem

© Fotolia

Many cancer patients suffer not only from health problems, but experience loss of income and out-of-pocket expenditures for medical services. This is true even in European countries with high incomes and comprehensive health insurance systems. This problem has been largely underestimated in the past and little systematic research has been carried out. The Organization of European Cancer Institutes (OECI) is now presenting consensus recommendations to guide future research into the socio-economic consequences of cancer.

read more

No. 12 | 14. March 2024 | by Koh

Machine learning classifier accelerates the development of cellular immunotherapies

© Adobe Stock

Making a personalised T cell therapy for cancer patients currently takes at least six months; scientists at the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.

read more

No. 09 | 12. February 2024 | by Koh

AI-supported image analysis: metrics determine quality

AI can support the evaluation of medical images - provided the metrics used...
© Adobe Stock

How well do the algorithms used in the AI-supported analysis of medical images perform their respective tasks? This depends to a large extent on the metrics used to evaluate their performance. An international consortium led by scientists from the German Cancer Research Center (DKFZ) and the National Center for Tumor Diseases (NCT) in Heidelberg has compiled the knowledge available worldwide on the specific strengths, weaknesses and limitations of the various validation metrics. With "Metrics Reloaded", the researchers are now providing a widely available online tool that supports users in selecting the most suitable algorithm for their task.

read more

No. 08c | 08. February 2024 | by Koh

Next generation models for brain tumor research


"GLO", glioblastoma-like organoids grown in the laboratory from human stem cells, are a suitable model for investigating the correlation between genetic mutations and molecular subtypes in glioblastoma. This was published by scientists from the German Cancer Research Center (DKFZ). When investigating the GLOs, they discovered that glioblastoma development is characterised by a reprogrammed lipid metabolism. This could be the starting point for developing new drugs.

read more

No. 08 | 07. February 2024 | by Koh

The unexpected long-term consequences of female fertility

Ovarian follicle
© TiagoLubiana/Wikimedia Commons

The constant remodeling of the organs of the female reproductive tract during the reproductive cycle leads to fibrosis and chronic inflammation over the years. Scientists from the German Cancer Research Center (DKFZ) have now uncovered these unexpected long-term consequences of female reproductive function in mice. The results have been published in the scientific journal CELL.

read more

No. 06 | 02. February 2024 | by Koh

Epigenetic status determines metastasis

Partially extravasated metastasizing tumor cells (pink) exiting from the pu...
© Augustin/DKFZ

Scientists from the German Cancer Research Center (DKFZ) and Medical Faculty Mannheim of the Heidelberg University investigated in mice how spreading tumor cells behave at the site of metastasis: Some tumor cells immediately start to form metastases. Others leave the blood vessel and may then enter a long period of dormancy. What determines which path the cancer cells take is their epigenetic status. This was also confirmed in experiments with human tumor cells. The results of the study could pave the way for novel diagnostic and therapeutic applications.

read more

No. 05c | 31. January 2024

Precursor of Cholesterol Protects Cancer Cells From Cell Death and Makes them Aggressive

Cancer Cells die from Ferroptosis
© H. Alborzinia/DKFZ

A precursor of cholesterol can protect cancer cells from a form of cell death known as ferroptosis. Scientists of the University of Würzburg, the German Cancer Research Center (DKFZ), and the Stem Cell Institute HI-STEM* published this finding in the journal Nature. The results opens up exciting prospects for further improving the treatment of cancer and other diseases associated with oxidative stress and ferroptosis.

read more


Subscribe to our RSS-Feed.

to top
powered by webEdition CMS