Cookie Settings

We use cookies to optimize our website. These include cookies that are necessary for the operation of the site, as well as those that are only used for anonymous statistic. You can decide for yourself which categories you want to allow. Further information can be found in our data privacy protection .

Essential

These cookies are necessary to run the core functionalities of this website and cannot be disabled.

Name Webedition CMS
Purpose This cookie is required by the CMS (Content Management System) Webedition for the system to function correctly. Typically, this cookie is deleted when the browser is closed.
Name econda
Purpose Session cookie emos_jcsid for the web analysis software econda. This runs in the “anonymized measurement” mode. There is no personal reference. As soon as the user leaves the site, tracking is ended and all data in the browser are automatically deleted.
Statistics

These cookies help us understand how visitors interact with our website by collecting and analyzing information anonymously. Depending on the tool, one or more cookies are set by the provider.

Name econda
Purpose Statistics
External media

Content from external video platforms is blocked by default. If cookies from external media are accepted, access to this content no longer requires manual consent.

Name Youtube
Purpose External media
Clinical Epidemiology and Aging Research

Division of Clinical Epidemiology and Aging Research

Prof. Dr. Hermann Brenner

© dkfz.de

The Clinical Epidemiology and Aging Research Division’s main areas of research include clinical cancer epidemiology, epidemiology of chronic age-related diseases and epidemiological methods. In the field of clinical cancer epidemiology, the group conducts large-scale epidemiological studies on new avenues of more effective cancer prevention and early detection, and on issues of the quality of medical care, prognosis and quality of life of cancer patients. Further large-scale epidemiological studies focuses on detection of risk factors, risk markers and prognostic factors of cardiovascular disease, diabetes mellitus and arthritis, thereby aiming to explore new avenues of enhanced prevention and management of these common and strongly age-related diseases. Most of the Division’s studies are conducted in interdisciplinary, oftentimes international collaborations with cancer registries, clinical partners and partners from basic research. Apart from the application of the highest methodological standards in these studies, a major area of research conducted in the Division is devoted to further development and enhancement of methods in epidemiological research.

FUTURE OUTLOOK
The Division will expand its research on early detection and screening for colorectal cancer to focus on questions of high relevance to the implementation of early detection programs at the population level.
Future research in early detection and screening will also be directed towards other gastrointestinal cancers. Due to demographic aging, along with steadily increasing cancer survival rates, the number and prevalence of cancer survivors in the population will continue to increase. The Division will therefore intensify its research on additional outcomes, such as quality of life, and the occupational and social participation of cancer survivors. An area of increasing interest in aging research will be to enhance the empirical evidence for preventive and therapeutic interventions in old age. Epidemiological aging research in the Division will increasingly address integrative and functional endpoints that have received comparatively little attention thus far, such as indicators of multi-morbidity and frailty, or indicators of functional limitations, as these are often more relevant for the elderly than single medical diagnoses. The Division will also contribute its expertise in recruitment and follow-up of population-based cohorts, including the areas of clinical epidemiology, aging research and epidemiological methods of the National Cohort, where 200,000 older adults are to be recruited in 2014-2018 and followed up many years afterwards.

Contact

Prof. Dr. Hermann Brenner
Clinical Epidemiology and Aging Research (C070)
Deutsches Krebsforschungszentrum
Im Neuenheimer Feld 581
69120 Heidelberg
Tel: +49 6221 42 1301
Fax: +49 6221 42 1302

Selected Publications

  • Cardoso R, Guo F, Heisser T, ..., Ryzhov A, Hoffmeister M, Brenner H. Colorectal cancer incidence, mortality, and stage distribution in European countries in the colorectal cancer screening era: an international population-based study. Lancet Oncol 2021;22(7):1002-1013.
  • Carr PR, Weigl K, Edelmann D, Jansen L, Chang-Claude J, Brenner H, Hoffmeister M. Estimation of Absolute Risk of Colorectal Cancer Based on Healthy Lifestyle, Genetic Risk, and Colonoscopy Status in a Population-Based Study. Gastroenterology 2020;159(1):129-138.e9.
  • Heisser T, Peng L, Weigl K, Hoffmeister M, Brenner H. Outcomes at follow-up of negative colonoscopy in average risk population: systematic review and meta-analysis. BMJ 2019;367:l6109.
  • Brenner H, Calderazzo S, Seufferlein T, Ludwig L, Dikopoulos N, Mangold J, Böck W, Stolz T, Eisenbach T, Block T, Kopp-Schneider A, Czock D, Tikk K. Effect of a Single Aspirin Dose Prior to Fecal Immunochemical Testing on Test Sensitivity for Detecting Advanced Colorectal Neoplasms: A Randomized Clinical Trial. JAMA 2019;321(17):1686-1692.
to top
powered by webEdition CMS