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Selected Publications "RNA Biology & Cancer"

S Dhamija*, CM Yang*, J Seiler, K Myacheva, M Caudron-Herger, A Wieland, M Abdelkarim, Y Sharma, M Riester, M Groß, J Maurer, S Diederichs: "A Pan-Cancer Analysis reveals Nonstop Extension Mutations causing SMAD4 Tumor Suppressor Degradation"
Nature Cell Biology (2020) 22: 999-1010

M Gandhi, M Groß
, JM Holler, SA Coggins, N Patil, JH Leupold, M Munschauer, M Schenone, CR Hartigan, H Allgayer, B Kim, S Diederichs: "The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer"
Nature Communications (2020) 11: 3214

M Caudron-Herger, E Wassmer, I Nasa, AS Schultz, J Seiler, AN Kettenbach, S Diederichs: "Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP"
Nature Protocols (2020) 15: 1338-1370

Y Sharma*,
M Miladi*, S Dukare*, K Boulay*, M Caudron-Herger, M Groß, R Backofen, S Diederichs: "A pan-cancer analysis of synonymous mutations"
Nature Communications (2019) 10: 2569

M Caudron-Herger
, SF Rusin, ME Adamo, J Seiler, V Schmid, E Barreau, AN Kettenbach, S Diederichs: "R-DeeP: Proteome-wide and Quantitative Identification of RNA-dependent Proteins by Density Gradient Ultracentrifugation"
Molecular Cell (2019) 75: 184-199

M Polycarpou-Schwarz, M Groß,
P Mestdagh, J Schott, SE Grund, C Hildenbrand, J Rom, S Aulmann, HP Sinn, J Vandesompele, S Diederichs: "The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation"
Oncogene (2018) 37: 4750-4768

A Goyal, K Myacheva, M Groß, M Klingenberg, B Duran-Arque, S Diederichs: "Challenges of CRISPR / Cas9 applications for long non-coding RNA genes"
Nucleic Acids Research (2017) 45: e12

S Diederichs et al.: "The dark matter of the cancer genome: Aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations"
EMBO Molecular Medicine (2016) 8: 442-457

A Roth, S Diederichs: "RAP and ChIRP about X inactivation"
Nature (2015) 521: 170-171

T Gutschner, M Hämmerle, M Eißmann, J Hsu, Y Kim, G Hung, AS Revenko, G Arun, M Stentrup, M Groß, M Zörnig, AR MacLeod, DL Spector, S Diederichs: "The non-coding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells"
Cancer Research (2013) 73: 1180-1189

 J Winter*, S Jung*, S Keller, RI Gregory, S Diederichs: "Many roads to maturity: microRNA biogenesis pathways and their regulation"
Nature Cell Biology (2009) 11: 228-234
 
S Diederichs, DA Haber: "Dual Role for Argonautes in microRNA Processing and post-transcriptional Regulation of microRNA Expression"
Cell (2007) 131: 1097-1108
 
P Ji*, S Diederichs*, W Wang, S Böing, R Metzger, PM Schneider, N Tidow, B Brandt, H Buerger, E Bulk, M Thomas, WE Berdel, H Serve, C Müller-Tidow: "MALAT-1, a novel non-coding RNA, and Thymosin b4 predict Metastasis and Survival in early-stage Non-Small Cell Lung Cancer"
Oncogene (2003) 22: 8031-8041

... Here, you can find our Top Impact Publications independent of the research topic.

Research Articles

2021

S Taromi, E Firat, A Simonis, LM Braun, P Apostolova, M Elze, B Passlick, A Schumacher, S Lagies, A Frey, A Schmitt-Graeff, M Burger, K Schmittlutz, M Follo, D von Elverfeldt, X Zhu, B Kammerer, S Diederichs, J Duyster, MG Manz, G Niedermann*, R Zeiser*: "Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer" Cancer Letters (2021) 520: 385-399

J Pal*, AC Becker*, S Dhamija, J Seiler, M Abdelkarim, Y Sharma
, J Behr, C Meng, C Ludwig, B Kuster, S Diederichs: "Systematic analysis of migration factors by MigExpress identifies essential cell migration control genes in non-small cell lung cancer" Molecular Oncology (2021) 15: 1797-1817

M Caudron-Herger, RE Jansen, E Wassmer, S Diederichs
: "RBP2GO: A comprehensive pan-species database on RNA-binding proteins, their interactions and functions" Nucleic Acids Research (2021) 49: D425-D436

R Onoguchi-Mizutani, Y Kirikae, Y Ogura, T Gutschner, S Diederichs, N Akimitsu: "Identification of Heat-Inducible Long Noncoding RNA MALAT1-Containing Novel Nuclear (HiNoCo) Body" Journal of Cell Science (2021) 134: jcs253559

2020

Q Hao*, X Zong*, Q Sun, YC Lin, YJ Song, S Hashemikhabir, RYC Hsu, M Kamran, R Chaudhary, V Tripathi, DK Singh, A Chakraborty, XL Li, YJ Kim, AV Orjalo, M Polycarpou-Schwarz, BS Moriarity, LM Jenkins, HE Johansson, YJ Zhu, S Diederichs, A Bagchi, TH Kim, SC Janga, A Lal, SG Prasanth, KV Prasanth: " The S phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway" eLIFE (2020) 9: e55102

Y Lyu, M Caudron-Herger, S Diederichs
: "circ2GO: A Database Linking Circular RNAs to Gene Function" Cancers (2020) 12: 2975

S Dhamija*, CM Yang*, J Seiler, K Myacheva, M Caudron-Herger, A Wieland, M Abdelkarim, Y Sharma, M Riester, M Groß,
J Maurer, S Diederichs: "A Pan-Cancer Analysis reveals Nonstop Extension Mutations causing SMAD4 Tumor Suppressor Degradation" Nature Cell Biology (2020) 22: 999-1010

M Gandhi, M Groß
, JM Holler, SA Coggins, N Patil, JH Leupold, M Munschauer, M Schenone, CR Hartigan, H Allgayer, B Kim, S Diederichs: "The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer" Nature Communications (2020) 11: 3214

M Miladi*, M Raden*, S Diederichs, R Backofen: "MutaRNA: analysis and visualisation of mutation-induced changes in RNA structure" Nucleic Acids Research (2020) 48: W287-W291

L Merta, A Gandalovicova, V Cermak, M Dibus, T Gutschner, S Diederichs, D Rosel, J Brabek: "Increased Level of Long Non-Coding RNA MALAT1 Represents a Hallmark of Amoeboid Invasion" Cancers (2020) 12: 1136

N Van Der Steen*, Y Lyu*, AK Hitzler*, AC Becker, J Seiler, S Diederichs: "The circular RNA landscape of Non-Small Cell Lung Cancer Cells" Cancers (2020) 12: 1091

M Caudron-Herger, E Wassmer, I Nasa, AS Schultz, J Seiler, AN Kettenbach, S Diederichs: "Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP" Nature Protocols (2020) 15: 1338-1370

2019

M Roatsch, I Hoffmann, M Abboud, R Hancock, H Tarhonskaya, KF Hsu, S Wilkins, TL Yeh, K Lippl, K Serrer, I Moneke, T Ahrens, D Robaa, S Wenzler, N Barthes, H Franz, W Sippl, S Lassmann, S Diederichs, E Schleicher, C Schofield, A Kawamura, R Schüle, M Jung: "The Clinically Used Iron Chelator Deferasirox is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases" ACS Chemical Biology (2019) 14: 1737-1750

Y Sharma*
, M Miladi*, S Dukare*, K Boulay*, M Caudron-Herger, M Groß, R Backofen, S Diederichs: "A pan-cancer analysis of synonymous mutations" Nature Communications (2019) 10: 2569

M Caudron-Herger
, SF Rusin, ME Adamo, J Seiler, V Schmid, E Barreau, AN Kettenbach, S Diederichs: "R-DeeP: Proteome-wide and Quantitative Identification of RNA-dependent Proteins by Density Gradient Ultracentrifugation" Molecular Cell (2019) 75: 184-199

I Tiessen, M Abildgaard, M Lubas, H Gylling, C Steinhauer, E Pietras, S Diederichs, L Frankel, A Lund: "A high-throughput screen identifies the long noncoding RNA DRAIC as a regulator of autophagy" Oncogene (2019) 38: 5127-5141

S Dhamija, AC Becker, Y Sharma, K Myacheva, J Seiler, S Diederichs: "LINC00261 and the adjacent gene FOXA2 are epithelial markers and are suppressed during lung cancer tumorigenesis and progression" Non-coding RNA (2019) 5: E2

2018

A Roth, K Boulay, M Groß, M Polycarpou-Schwarz, FA Mallette, M Regnier, O Bida, D Ginsberg, A Warth, PA Schnabel, T Muley, M Meister, H Zabeck, H Hoffmann, S Diederichs: "Targeting LINC00673 expression triggers cellular senescence in lung cancer" RNA Biology (2018) 15: 1499-1511

Q Sun*, V Tripathi*,#, JH Yoon#, DK Singh, Q Hao, KW Min, S Davila, RW Zealy, XL Li, M Polycarpou-Schwarz, E Lehrmann, Y Zhang, KG Becker, SM Freier, Y Zhu, S Diederichs, SG Prasanth, A Lal, M Gorospe, KV Prasanth#: "MIR-100 host gene-encoded lncRNAs regulate cell cycle by modulating the interaction between HuR and its target mRNAs" Nucleic Acids Research (2018) 46: 10405-10416

M Klingenberg, M Groß, A Goyal, M Polycarpou-Schwarz,
T Miersch, AS Ernst, J Leupold, N Patil, U Warnken, H Allgayer, T Longerich, P Schirmacher, M Boutros, S Diederichs: "The lncRNA CASC9 and RNA binding protein HNRNPL form a complex and co-regulate genes linked to AKT signaling" Hepatology (2018) 68: 1817-1832

M Polycarpou-Schwarz, M Groß,
P Mestdagh, J Schott, SE Grund, C Hildenbrand, J Rom, S Aulmann, HP Sinn, J Vandesompele, S Diederichs: "The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation" Oncogene (2018) 37: 4750-4768

G Dumbović, J Biayna, J Banús, J Samuelsson, A Roth, S Diederichs, S Alonso, M Buschbeck, M Perucho*, SV Forcales*: "A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer" Nucleic Acids Research (2018) 46: 5504-5524

T Mlambo, S Nitsch, M Hildenbeutel, M Romito, M Müller, C Bossen, S Diederichs, T Cornu, T Cathomen, C Mussolino: "Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells" Nucleic Acids Research (2018) 46: 4456-4468

R Soares, G Maglieri, T Gutschner, S Diederichs, A Lund, B Nielsen, K Holmstrøm: "Evaluation of fluorescence in situ hybridization techniques to study long non-coding RNA expression in cultured cells" Nucleic Acids Research (2018) 46: e4

I Moneke, JT Kaifi, R Kloeser, P Samson, B Haager, S Wiesemann, S Diederichs, B Passlick: "Pulmonary metastasectomy for thyroid cancer as salvage therapy for radioactive iodine-refractory metastases" European Journal of Cardio-Thoracic Surgery (2018) 53: 625-630

M Caudron-Herger, S Diederichs: "Mitochondrial mutations in human cancer: Curation of translation" RNA Biology (2018) 15: 62-69

2017

A Goyal, E Fiskin, T Gutschner, M Polycarpou-Schwarz, M Groß, J Neugebauer, M Gandhi, M Caudron-Herger, V Benes, S Diederichs: "A cautionary tale of sense-antisense gene pairs: Independent regulation despite inverse correlation of expression" Nucleic Acids Research (2017) 45: 12496-12508

F Haderk, R Schulz, M Iskar, LL Cid, T Worst, KV Willmund, A Schulz, U Warnken, J Seiler, A Benner, M Nessling, T Zenz, M Göbel, J Dürig, S Diederichs, J Paggetti, E Moussay, S Stilgenbauer, M Zapatka, P Lichter, M Seiffert: "Tumor-derived exosomes modulate PD-L1 expression in monocytes" Science Immunology (2017) 2: eaah5509

L Nötzold, L Frank, M Gandhi, M Polycarpou-Schwarz, M Groß
, M Gunkel, N Beil, H Erfle, N Harder, K Rohr, J Trendel, J Krijgsveld, T Longerich, P Schirmacher, M Boutros, S Erhardt, S Diederichs: "The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells" Scientific Reports (2017) 7: 2265

J Seiler,
M Breinig, M Caudron-Herger, M Polycarpou-Schwarz, M Boutros, S Diederichs: "The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance" Nucleic Acids Research (2017) 45: 5458-5469

K Das, D Eisel, C Lenkl, A Goyal, S Diederichs, E Dickes, W Osen, SB Eichmüller: "Generation of murine tumor cell lines deficient in MHC molecule surface expression using the CRISPR/Cas9 system" PLoS ONE (2017) 12: e0174077

A Goyal, K Myacheva, M Groß, M Klingenberg, B Duran-Arque, S Diederichs
: "Challenges of CRISPR / Cas9 applications for long non-coding RNA genes" Nucleic Acids Research (2017) 45: e12

2016

A Diaz-Lagares, A Crujeiras, P Lopez-Serra, M Soler, F Setien, A Goyal, J Sandoval, Y Hashimoto, A Martinez-Cardus, A Gomez, H Heyn, C Moutinho, J Espada, A Vidal, M Paúles, M Galan, N Sala, Y Akiyama, M Martínez-Iniesta, L Farré, A Villanueva, M Gross, S Diederichs, S Guil*, M Esteller*: "Epigenetic Inactivation of the p53-Induced Long Noncoding RNA TP53TG1 in Human Cancer" Proc Natl Acad Sci USA (2016) 113: E7535-7544

A Sas-Chen, MR Aure, L Leibovich, S Carvalho, Y Enuka, C Körner, M Polycarpou-Schwarz, S Lavi, N Nevo, Y Kuznetsov, J Yuan, F Azuaje, Oslo Breast Cancer Research Consortium (OSBREAC), I Ulitsky, S Diederichs, S Wiemann, Z Yakhini, VN Kristensen, AL Børresen-Dale, Y Yarden: "LIMT, a novel metastasis inhibiting lncRNA is suppressed by EGF and down-regulated in aggressive breast cancer" EMBO Molecular Medicine (2016) 8: 1052-1064

S Link*, S Grund*, S Diederichs
: "Alternative splicing affects the subcellular localization of Drosha" Nucleic Acids Research (2016) 44: 5330-5343
 
K Nöske, HJ Stark, L Nevaril, M Berning, L Langbein, A Goyal, S Diederichs, P Boukamp: "Mitotic Diversity in homeostatic human interfollicular epidermis" International Journal of Molecular Sciences (2016) 17: 167 
 
J Haar, M Contrant, K Bernhardt, R Feederle, S Diederichs, S Pfeffer, HJ Delecluse: "The expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation" Nucleic Acids Research (2016) 44: 1326-1341

2015

RM de Guia, AJ Rose, A Sommerfeld, O Seibert, D Strzoda, A Zota, Y Feuchter, A Krones-Herzig, T Sijmonsma, M Kirilov, C Sticht, N Gretz, G Dallinga-Thie, S Diederichs, N Klöting, M Blüher. M Berriel Diaz, S Herzig: "microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis" EMBO Journal (2015) 34: 344-360

2014

T Gutschner*, M Hämmerle*, N Pazaitis*, N Bley, E Fiskin, H Uckelmann, A Heim, M Groß, N Hofmann, R Geffers, B Skawran, T Longerich, K Breuhahn, P Schirmacher, B Mühleck, S Hüttelmaier*, S Diederichs*: "The Insulin-like Growth Factor 2 mRNA-Binding Protein 1 (IGF2BP1) is an important pro-tumorigenic factor in hepatocellular carcinoma" Hepatology (2014) 59: 1900-1911

L Quagliata, MS Matter, S Piscuoglio, L Arabi, C Ruiz, A Procino, M Kovac, F Moretti, Z Makowska, T Boldanova, JB Andersen, M Hämmerle, L Tornillo, MH Heim, S Diederichs, C Cillo*, LM Terracciano*: "IncRNA HOTTIP / HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients" Hepatology (2014) 59: 911-923

D Nachmani, T Gutschner, A Reches, S Diederichs*, O Mandelboim*: "RNA binding proteins regulate the expression of the immune activating ligand MICB" Nature Communications (2014) 5: 4186

2013

M Liu, A Roth, M Yu, R Morris, F Bersani, MN Rivera, J Lu, T Shioda, S Vasudevan, S Ramaswamy, S Maheswaran, S Diederichs*, DA Haber*: "The IGF2-intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis" Genes & Development (2013) 27: 2543-2548 

J Winter, S Diederichs: "Argonaute-3 activates the let-7a passenger strand microRNA" RNA Biology (2013) 10: 1631-1643 

M Hämmerle*, T Gutschner*, H Uckelmann, S Ozgur, E Fiskin, M Groß, B Skawran, R Geffers, T Longerich, K Breuhahn, P Schirmacher, G Stoecklin, S Diederichs: "Post-transcriptional destabilization of the liver-specific long non-coding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1)" Hepatology (2013) 58: 1703-1712

M Eißmann, B Schwamb, IM Melzer, J Moser, D Siele, U Köhl, RJ Rieker, DL Wachter, A Agaimy, E Herpel, P Baumgarten, M Mittelbronn, S Rakel, D Kögel, S Böhm, T Gutschner, S Diederichs, M Zörnig: "A functional yeast survival screen of tumor-derived cDNA libraries designed to identify anti-apoptotic mammalian oncogenes" PLoS ONE (2013) 8: e64873 

J Winter, S Link, D Witzigmann, C Hildenbrand, C Previti, S Diederichs: "Loop-miRs: Active microRNAs generated from single-stranded loop regions" Nucleic Acids Research (2013) 41: 5503-5512     

T Gutschner, M Hämmerle, M Eißmann, J Hsu, Y Kim, G Hung, AS Revenko, G Arun, M Stentrup, M Groß, M Zörnig, AR Mac Leod, DL Spector, S Diederichs: "The non-coding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells" Cancer Research (2013) 73: 1180-1189

T Palm, K Hemmer, J Winter, I Fricke, K Tarbashevich, F Sadegi Shakib, I Rudolph, A Hillje, P De Lucca, L Bahnassawy, R Madel, T Viel, A de Siervi, A Jacobs, S Diederichs, J Schwamborn: "A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop" Nucleic Acids Research (2013) 41: 3699-3712

C Luo, PW Tetteh, PR Merz, E Dickes, A Abukiwan, A Hotz-Wagenblatt, S Holland-Cunz, T Sinnberg, B Schittek, D Schadendorf, S Diederichs, SB Eichmüller: "miR-137 inhibits the invasion of melanoma cells through down-regulation of multiple oncogenic target genes" Journal of Investigative Dermatology (2013) 133: 768-775

2012

M Faryna*, C Konermann*, S Aulmann, J Lorenzo Bermejo, M Brugger, S Diederichs, J Rom, D Weichenhan, R Claus, M Rehli, P Schirmacher, HP Sinn, C Plass, C Gerhäuser: "Genome-wide methylation screen in low-grade breast cancer to identify novel diagnostic and prognostic markers" FASEB Journal (2012) 26: 4937-4950 

M Eißmann*, T Gutschner*, M Hämmerle, S Günther, M Caudron-Herger, M Groß, P Schirmacher, K Rippe, T Braun, M Zörnig*, S Diederichs*: "Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development" RNA Biology (2012) 9: 1076-1087

SE Grund, M Polycarpou-Schwarz, C Luo, SB Eichmüller, S Diederichs: "Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells" Neoplasia (2012) 14: 238-248

A Heinemann, F Zhao, S Pechlivanis, J Eberle, A Steinle, S Diederichs, D Schadendorf, A Paschen: "Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress induced ligand of the natural killer cell receptor NKG2D" Cancer Research (2012) 72: 460-471

2011

T Gutschner, M Baas, S Diederichs: "Non-coding RNA gene silencing through genomic integration of RNA destabilizing elements using zinc finger nucleases" Genome Research (2011) 21: 1944-1954

J Winter, S Diederichs: "Argonaute proteins regulate microRNA stability" RNA Biology (2011) 8: 1149-1157

M Ganzinger, T Noack, S Diederichs, T Longerich, P Knaup: "Service-oriented Data Integration for a Biomedical Research Network" Studies in Health Technology and Informatics (2011) 169: 867-871

C Kahlert, F Klupp, K Brand, F Lasitschka, S Diederichs, J Kirchberg, N Rahbari, S Dutta, U Bork, J Fritzmann, C Reissfelder, M Koch, J Weitz: "Invasion front specific expression and prognostic significance of microRNAs in colorectal liver metastases" Cancer Science (2011) 102: 1799-1807

N Bäumer*, L Tickenbrock*, P Tschanter*, L Lohmeyer, S Diederichs, S Bäumer, BV Skryabin, F Zhang, S Agrawal-Singh, G Koehler, WE Berdel, H Serve, S Koschmieder, C Müller-Tidow: "Inhibitor of CDK interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling" Journal of Biological Chemistry (2011) 286: 28210-28222

2010

P de Souza Rocha Simonini*, A Breiling*, N Gupta, M Malekpour, M Youns, R Omranipour, F Malekpour, S Volinia, CM Croce, H Najmabadi, S Diederichs, Ö Sahin, D Mayer, F Lyko, JD Hoheisel, Y Riazalhosseini: "Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with Estrogen Receptor alpha in breast cancer cells" Cancer Research (2010) 70: 9175-9184

I Surolia*, SP Pirnie*, V Chellappa*, KN Taylor*, A Cariappa*, J Moya, H Liu, DW Bell, D Driscoll, S Diederichs, K Haider, I Netravali, S Le, R Elia, E Dow, A Lee, J Freudenberg, PL De Jager, Y Chretien, A Varki, ME MacDonald, T Gillis, TW Behrens, D Bloch, D Collier, J Korzenik, DK Podolsky, D Hafler, M Murali, B Sands, JH Stone, PK Gregersen, S Pillai: "Functionally defective germline variants of sialic acid acetylesterase in autoimmunity" Nature (2010) 466: 243-247

2008

S Maheswaran*, LV Sequist*, S Nagrath*, L Ulkus, B Brannigan, C Collura, E Inserra, S Diederichs, AJ Iafrate, DW Bell, S Digumarthy, A Muzikansky, D Irimia, J Settleman, RG Tompkins, TJ Lynch, M Toner, DA Haber: "Detecting Epidermal Growth Factor Receptor Mutations in Circulating Tumor Cells from Patients with Non-Small Cell Lung Cancer" New England Journal of Medicine (2008) 359: 366-377

S Diederichs, S Jung, SM Rothenberg, GA Smolen, BG Mlody, DA Haber: "Co-expression of Argonaute-2 enhances RNA Interference towards perfect match binding sites" Proceedings of the National Academy of Sciences U.S.A. (2008) 105: 9284-9289

E Bulk, A Hascher, R Liersch, RM Mesters, S Diederichs, B Sargin, V Gerke, M Hotfilder, J Vormoor, WE Berdel, H Serve, C Müller-Tidow: "Adjuvant therapy with small hairpin RNA prevents NSCLC metastasis development in mice" Cancer Research (2008) 68: 1896-1904

2007

S Diederichs, DA Haber: "Dual Role for Argonautes in microRNA Processing and post-transcriptional Regulation of microRNA Expression" Cell (2007) 131: 1097-1108

GA Smolen, BJ Schott, RA Stewart, S Diederichs, B Muir, HL Provencher, AT Look, DC Sgroi, RT Peterson, DA Haber: "A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors" Genes & Development (2007) 21: 2131-2136

P Ji, N Bäumer, T Yin, S Diederichs, F Zhang, C Beger, K Welte, S Fulda, WE Berdel, H Serve, C Müller-Tidow: "The DNA damage response involves modulation of Ku70 and Rb functions by cyclin A1 in leukemia cells" International Journal of Cancer (2007) 121: 706-713

2006

S Diederichs, DA Haber: "Sequence Variations of microRNAs in human Cancer: Alterations in predicted secondary Structure do not affect Processing" Cancer Research (2006) 66: 6097-6104

2005

M Böhm, M Eickelmann, Z Li, SW Schneider, V Oji, S Diederichs, GS Barsh, A Vogt, K Stieler, U Blume-Peytavi, TA Luger: "Detection of functionally active melanocortin receptors and evidence for an immunoregulatory activity of α-melanocyte-stimulating hormone in human dermal papilla cells" Endocrinology (2005) 146: 4635-4646

P Ji, S Agrawal, S Diederichs, N Bäumer, A Becker, T Cauvet, S Kowski, C Beger, K Welte, WE Berdel, H Serve, C Müller-Tidow: "Cyclin A1, the alternative A-type cyclin, contributes to G1/S cell cycle progression in somatic cells" Oncogene (2005) 24: 2739-2744

S Diederichs, N Bäumer, N Schultz, FK Hamra, MG Schrader, ML Sandstede, WE Berdel, H Serve, C Müller-Tidow: "Expression Patterns of Mitotic and Meiotic Cell Cycle Regulators in Testicular Cancer and Development" International Journal of Cancer (2005) 116: 207-217

C Müller-Tidow*, S Diederichs*, E Bulk, T Pohle, B Steffen, J Schwäble, S Plewka, M Thomas, R Metzger, PM Schneider, C Brandts, WE Berdel, H Serve: "Identification of Metastasis-associated Receptor Tyrosine Kinases in Non-Small Cell Lung Cancer" Cancer Research (2005) 65: 1778-1782

2004

C Müller-Tidow*, P Ji*, S Diederichs, J Potratz, C Beger, M Carrington, G Köhler, T Cauvet, A Yasmeen, E Bulk, HP Koeffler, WE Berdel, H Serve: "Cyclin A1 is induced by p53 following DNA damage and modulates DNA repair by interacting with Ku proteins" Molecular and Cellular Biology (2004) 24: 8917-8928

S Diederichs, E Bulk, B Steffen, P Ji, L Tickenbrock, K Lang, KS Zänker, R Metzger, PM Schneider, V Gerke, M Thomas, WE Berdel, H Serve, C Müller-Tidow: "S100 family members and Trypsinogens are predictors of distant Metastasis and Survival in early-stage Non-Small Cell Lung Cancer" Cancer Research (2004) 64: 5564-5569

S Diederichs, N Bäumer, P Ji, SK Metzelder, GE Idos, T Cauvet, W Wang, M Möller, S Pierschalski, J Gromoll, MG Schrader, HP Koeffler, WE Berdel, H Serve, C Müller-Tidow: "Identification of Interaction Partners and Substrates of the Cyclin A1/CDK2 complex" Journal of Biological Chemistry (2004) 279: 33727-33741

C Müller-Tidow*, B Steffen*, T Cauvet, L Tickenbrock, P Ji, S Diederichs, B Sargin, G Köhler, M Stelljes, E Puccetti, M Ruthardt, S de Vos, SW Hiebert, HP Koeffler, WE Berdel, H Serve: "Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells" Molecular and Cellular Biology (2004) 24: 2890-2904

2003

P Ji*, S Diederichs*, W Wang, S Böing, R Metzger, PM Schneider, N Tidow, B Brandt, H Buerger, E Bulk, M Thomas, WE Berdel, H Serve, C Müller-Tidow: "MALAT-1, a novel non-coding RNA, and Thymosin b4 predict Metastasis and Survival in early-stage Non-Small Cell Lung Cancer" Oncogene (2003) 22: 8031-8041

C Müller-Tidow, C Readhead, AH Cohen, K Asotra, GE Idos, S Diederichs, T Cauvet, R Yang, WE Berdel, H Serve, HP Koeffler: "Successive increases in human cyclin A1 promoter activity during spermatogenesis in transgenic mice" International Journal of Molecular Medicine (2003) 11: 311-315

C Müller-Tidow, S Diederichs, MG Schrader, U Vogt, K Miller, WE Berdel, H Serve: "Cyclin A1 is highly expressed in aggressive testicular germ cell tumors" Cancer Letters (2003) 190: 89-95

PM Sincock, IG Ganley, JP Krise, S Diederichs, U Sivars, B O’Connor, L Ding, SR Pfeffer: "Self-Assembly Is Important for TIP47 Function in Mannose 6-Phosphate Receptor Transport" Traffic (2003) 4: 18-25

2002

M Schrader, C Müller-Tidow, S Ravnik, M Müller, W Schulze, S Diederichs, H Serve, K Miller: "Cyclin A1 and gametogenesis in fertile and infertile patients: a potential new molecular diagnostic marker" Human Reproduction (2002) 17: 2338-2343

2001

C Müller-Tidow, K Kügler, S Diederichs, S Klümpen, A Westermann, P Zuo, U Vogt, R Metzger, PM Schneider, WE Berdel, H Serve: "Loss of expression of HDAC-recruiting Methyl-CpG binding domain proteins in human cancer" British Journal of Cancer (2001) 85: 1168-1174

C Müller-Tidow, W Wang, GE Idos, S Diederichs, R Yang, C Readhead, WE Berdel, H Serve, M Saville, R Watson, HP Koeffler: "Cyclin A1 directly interacts with B-myb and Cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function" Blood (2001) 97: 2091-2097

C Müller-Tidow, R Metzger, K Kügler, S Diederichs, GE Idos, M Thomas, B Dockhorn-Dworniczak, PM Schneider, HP Koeffler, WE Berdel, H Serve: "Cyclin E is the Only Cyclin-dependent Kinase 2-associated Cyclin that Predicts Metastasis and Survival in Early Stage Non-Small Cell Lung Cancer" Cancer Research (2001) 61: 647-653

C Müller-Tidow, C Bornemann, S Diederichs, A Westermann, S Klümpen, P Zuo, W Wang, WE Berdel, H Serve: "Analyses of the genomic methylation status of the human Cyclin A1 promoter by a novel real-time PCR-based methodology" FEBS Letters (2001) 490: 75-79

2000

C Müller, C Readhead, S Diederichs, GE Idos, R Yang, N Tidow, H Serve, WE Berdel, HP Koeffler: "Methylation of the Cyclin A1 Promoter Correlates with Gene Silencing in Somatic Cell Lines, while Tissue-Specific Expression of Cyclin A1 is Methylation Independent" Molecular and Cellular Biology (2000) 20: 3316-3329

1999

C Müller, R Yang, GE Idos, N Tidow, S Diederichs, OM Koch, W Verbeek, TP Bender, HP Koeffler: "c-myb Transactivates the Human Cyclin A1 Promoter and Induces Cyclin A1 Gene Expression" Blood (1999) 94: 4255-4262

  

Review Articles & Book Chapters

M Caudron-Herger, S Diederichs: "Insights from the degradation mechanism of Cyclin D into targeted therapy of the cancer cell cycle" Signal Transduction & Targeted Therapy (2021) 6: 311

M Gandhi, M Caudron-Herger, S Diederichs
: "RNA motifs and combinatorial prediction of non-coding RNA interaction, stability and localization" Nature Structural & Molecular Biology (2018) 25: 1070-1076

M Klingenberg,
A Matsuda, S Diederichs*, T Patel*: "Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets" Journal of Hepatology (2017) 67: 603-618

S Diederichs, L Bartsch*, JC Berkmann*, K Fröse*, J Heitmann*, C Hoppe*, D Iggena*, D Jazmati*, P Karschnia*, M Linsenmeier*, T Maulhardt*, L Möhrmann*, J Morstein*, SV Paffenholz*, P Röpenack*, T Rückert*, L Sandig*, M Schell*, A Steinmann*, G Voss*, J Wasmuth*, ME Weinberger*, R Wullenkord*: "The dark matter of the cancer genome: Aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations" EMBO Molecular Medicine (2016) 8: 442-457

S Dhamija, S Diederichs: "From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis" International Journal of Cancer (2016) 139: 269-280

A Roth, S Diederichs: "RAP and ChIRP about X inactivation" Nature (2015) 521: 170-171

A Roth, S Diederichs: "Long non-coding RNAs in lung cancer" Current Topics in Microbiology & Immunology (2016) 394: 57-110

S Diederichs: "micro-Terminator: 'Hasta la vista, lncRNA !' " Nature Structural & Molecular Biology (2015) 22: 279-281

G Stoecklin, S Diederichs: "tRNAs: New tricks from old dogs" EMBO Journal (2014) 33: 1981-1983

S Diederichs: "The four dimensions of non-coding RNA conservation" Trends in Genetics (2014) 30: 121-123

H Sültmann, S Diederichs: "Long non-coding RNA: LNCs to cancer" European Urology (2014) 65: 1152-1153

T Gutschner, M Hämmerle, S Diederichs: "MALAT 1 - a paradigm for long noncoding RNA function in cancer" Journal of Molecular Medicine (2013) 91, (7): 791-801

T Gutschner, S Diederichs: "The Hallmarks of Cancer: A long non-coding RNA point of view" RNA Biology (2012) 9: 703-719

S Diederichs: "Non-coding RNA and disease" RNA Biology (2012) 9: 701-702

SK Abd Ellatif, T Gutschner, S Diederichs: "Long Noncoding RNA Function and Expression in Cancer" in Regulatory RNAs, edited by Bibekanand Mallick & Zhumur Ghosh (2012) 197-226

J Winter*, A Roth*, S Diederichs: "RNA meets Disease in Paradise" RNA Biology (2011) 8: 984-987

J Winter, S Diederichs: "microRNA Northern Blotting, Precursor Cloning & Ago2-improved RNA interference" in Methods in Molecular Biology: microRNA & Cancer, edited by Wei Wu (2011) 85-100

J Winter, S Diederichs: "microRNA Biogenesis and Cancer" in Methods in Molecular Biology: microRNA & Cancer, edited by Wei Wu (2011) 3-22

S Grund, S Diederichs: "microRNA Biogenesis and its impact on RNA interference" in RNA Technologies and Their Applications, edited by VA Erdmann & J Barciszewski (2010) 325-354

S Diederichs: "Non-coding RNA in malignant tumors : A new world of tumor biomarkers and target structures in cancer cells" [German] Pathologe (2010) S2: 258-262

J Winter*, S Jung*, S Keller, RI Gregory, S Diederichs: "Many roads to maturity: microRNA biogenesis pathways and their regulation" Nature Cell Biology (2009) 11: 228-234

C Müller-Tidow, S Diederichs, M Thomas, H Serve: "Genome wide screening for prognosis predicting genes in early stage non-small cell lung cancer" Lung Cancer (2004) 45: S145-S150

   

Oral Presentations

S Diederichs: "Long non-coding RNAs and RNA-dependent Proteins in Cancer", EMBO Meeting "The non-coding Genome", Heidelberg, Germany, October 2021

S Diederichs: "From non-coding RNA to non-canonical Mutations in Cancer", University of Halle, Halle (Saale), Germany, September 2021

S Diederichs: "Non-canonical Mutations & non-coding RNAs in Cancer", Charité & DKTK, Berlin, Germany, August 2021

S Diederichs: "Long non-coding RNAs and RNA-dependent Proteins in Cancer", ncRNA 2021, Basel, Switzerland, July 2021

S Diederichs: "Non-coding RNAs and RNA-dependent Proteins in Cancer", iTARGET Munich / Elitenetzwerk Bayern, Munich, Germany, November 2020

S Diederichs: "Non-canonical Mutations in Cancer", Research Highlights @ DKTK Retreat, Heidelberg, Germany, October 2020

S Diederichs: "RNA-dependent Proteins & Non-coding RNAs in Cancer", SFB 960 Symposium, Regensburg, Germany, June 2020

S Diederichs: "Long non-coding RNAs in Cancer Metabolism", Institut Marie Curie, Paris, France, February 2020

M Caudron-Herger: "RNA-dependent proteins", Institut Marie Curie, Paris, France, February 2020

S Diederichs: "The uncharted Territory of the Cancer Genome", Life Science Institute (LSI) Vancouver, Canada, January 2020

S Diederichs: "RNA-Dependent Proteins and Non-Coding RNAs in Cancer" Keystone Meeting "Non-Coding RNAs", Whistler, Canada, January 2020

S Diederichs: "Non-canonical Mutations in Cancer" DKTK Dresden Symposium, Dresden, Germany, January 2020

S Diederichs: "RNA-Dependent Proteins and Non-Coding RNAs in Cancer" RTG 2355 Retreat, Gießen, November 2019

S Diederichs: "Non-canonical Mutations in Cancer" DKTK Frankfurt Symposium, Frankfurt, Germany, November 2019

S Diederichs: "Non-canonical Mutations in Cancer" 47th DKTK Munich Cancer Colloquium, München, Germany, November 2019

K Myacheva: "Novel Oncogenes in Lung Cancer revealed by CRISPRi Screening" Future of Medicine, Berlin, Germany, November 2019

S Dhamija*, CM Yang*, M Caudron-Herger, A Wieland, K Myacheva, M Abdelkarim, Y Sharma, J Seiler, J Maurer, S Diederichs: "A Pan-Cancer Analysis reveals Nonstop Mutations causing SMAD4 Tumor Suppressor Degradation", EMBO Meeting "Cancer Genomics", Heidelberg, Germany, November 2019 

S Diederichs: "Non-canonical Mutations in Cancer" 40th Anniversary Symposium CCCF, Freiburg, Germany, October 2019

"Molecular determinants of lung adenocarcinoma metastasis and epigenetic therapy response", 8th Langendorff Symposium, Freiburg, Germany, March 2019

S Diederichs: "The RNA World in Cancer", Institut Marie Curie, Paris, France, February 2019

M Caudron-Herger: "Proteome-wide and quantitative identification of RNA-dependent proteins", Institut Marie Curie, Paris, France, February 2019

M Caudron-Herger: "Proteome-wide and quantitative identification of RNA-dependent protein complexes”, Keystone Symposium on RNA-Protein Interactions, Whistler, Canada, February 2019 

S Diederichs: "Long non-coding RNAs & RNA-dependent proteins in cancer", University of Bern, Bern, Switzerland, October 2018

S Diederichs: "Proteome-wide and Quantitative Identification of RNA-dependent Proteins", GBM RNA Biochemistry, Bonn, Germany, October 2018

S Diederichs: "Non-coding RNA in Lung Cancer", IASLC World Lung Cancer Meeting, Toronto, Canada, September 2018

M Caudron-Herger, SF Rusin, ME Adamo, J Seiler, V Schmid, AN Kettenbach S Diederichs: "Proteome-wide and quantitative identification of RNA-dependent protein complexes – a novel concept to discover unexpected functions of RNAs", RNA Society Meeting, Berkeley, USA, May 2018

S Diederichs: "Die dunkle Materie des Genoms: Nicht-codierende RNA - Eine neue Welt
in der Krebsforschung", Akademische Mittagspause, Peterskirche, Heidelberg, Germany, April 2018

S Diederichs: "The dark matter of the cancer genome: Long non-coding RNAs and RNA-dependent proteins in Cancer", IBMC Strasbourg, France, June 2018

S Diederichs: "Non-coding RNA and RNA-dependent proteins complexes in human cancer", Institut Marie Curie, Paris, France, February 2018

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", SFB 960, Regensburg, Germany, October 2017

S Diederichs: "Molecular Genetics of Lung Cancer & Metastasis - A non-coding Perspective", 21. Chirurgische Forschungstage, Cologne, Germany, September 2017

S Diederichs: "IncRNAs & Ribonucleoproteins in Lung Cancer", Loewe-Symposium Medical RNomics, Giessen, Germany, September 2017

S Diederichs: "MALAT1 and beyond - Long non-coding RNAs in Lung Cancer", ISFMS 2017: Non-Coding RNAs and Epigenetics in Cancer, Basel, Switzerland, June 2017

S Diederichs: "Long non-coding RNAs in Metastasis & Migration", SFB850 Cell Migration Symposium, Freiburg, Germany, March 2017

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", F-Tales Meeting, Leuven, Belgium, March 2017

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", University of Tübingen, Tübingen, Germany, November 2016

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", NCRI Conference “Noncoding RNAs in cancer”, Liverpool, United Kingdom, November 2016

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", 3. DGP Nachwuchsakademie, Kloster Johannisberg, Germany, October 2016

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", Perspectives in Vascular Biology 2016,Frankfurt, Germany, September 2016

S Diederichs: "Long non-coding RNAs in Lung Cancer & Signaling", BIOSS Centre for Biological Signalling Studies, Freiburg, Germany, September 2016

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", Opening Symposium "Center for Translational Cell research" (ZTZ), Freiburg, Germany, September 2016

S Diederichs: "Success in a scientific team", Helmholtz Akademie Kamingespräch, Berlin, Germany, September 2016 

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", SFB 992 "Medical Epigenetics", Freiburg, Germany, May 2016

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", Center for Chronic Immunodeficiencies (CCI), Freiburg, Germany, April 2016

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", Marie Curie ITN RNAtrain, Fischbachau, Germany, March 2016

S Diederichs: "Long non-coding RNAs - Messages from the dark matter of the cancer genome", Düsseldorf School of Oncology, Düsseldorf, Germany, March 2016

S Diederichs: "Long non-coding RNAs in Cancer" Harvard Medical School / Beth Israel Deaconess Medical Center, Boston, USA, December 2015

S Diederichs: "Long non-coding RNAs in Cancer" Broad Institute, Cambridge, USA, December 2015

S Diederichs: "Long non-coding RNAs in Cancer" Harvard Medical School / Massachusetts General Hospital Cancer Center, Boston, USA, December 2015

S Diederichs: "Long non-coding RNAs in Cancer" Harvard Medical School, Boston, USA, December 2015

S Diederichs: "Long non-coding RNAs in Cancer" Dartmouth College, Hanover, USA, December 2015

S Diederichs: "Long non-coding RNA in Lung Cancer" AACR Conference "Noncoding RNAs and Cancer: Mechanisms to Medicines", Boston, USA, December 2015

S Diederichs: "Long non-coding RNA in Cancer" Royal Society, "Long non-coding RNAs: Evolution of new epigenetic and post-transcriptional functions" Buckinghamshire, UK, September 2015 

S Diederichs: "Long non-coding RNAs in Cancer", 1st Aegean Conference on Non-Coding RNAs, Crete, Greece, June 2015

S Diederichs: "What junior scientists need for success", Karolinka Institutet Workshop "Career Systems for Academic Excellence in Europe", Stockholm, Sweden, June 2015

S Diederichs: "The IncRNA Malat1 is a marker, active player and therapeutic target in lung cancer metastasis", 99. Jahrestagung DGP, Frankfurt, Germany, May 2015 

S Diederichs: "Long non-coding RNA in Cancer" Netherlands Cancer Institute, Symposium "Epigenetics and non-coding RNA´s in cancer and development", Amsterdam, Netherlands, May 2015

S Diederichs: "Nicht-kodierende RNA - Eine neue Welt in der Krebsforschung", Universität des Saarlandes, Vortragsreihe der DPhG, Saarbrücken, Germany, May 2015

S Diederichs: "Long non-coding RNAs and Epigenetics in Lung in Cancer" Keystone Symposium "Long noncoding RNA: From Evolution to Function", Keystone, Colorado, March 2015

S Diederichs: "Long non-coding RNAs in Liver Cancer" Marie Curie Workshop "Liver Cancer - From Molecular Pathogenesis to Target Therapies", Mannheim, Germany, March 2015

S Diederichs: "Long non-coding RNAs and Epigenetics in Lung Cancer" German-Catalan-Epigenetics Workshop, Barcelona, Spain, November 2014

S Diederichs: "Long non-coding RNAs in Cancer" RNA Train Berlin MDC, Berlin, Germany, October 2014

S Diederichs: "Non-coding RNA & Cancer", DGP Nachwuchsakademie Eberbach, Eberbach, Germany, October 2014

S Diederichs: "Long non-coding RNAs in Lung Cancer" 26th International IGB Workshop "Decoding non-coding RNAs in development and cancer" Capri, Italy, October 2014

S Diederichs: "Long non-coding RNAs in Cancer" Marie Curie ITN „RNATrain“, MDC Berlin, Germany, October 2014

S Diederichs: Long non-coding RNAs in cancer" Roche Penzberg, Germany, October 2014

S Diederichs: "Long non-coding RNAs in Cancer" Symposium "Free circulating nucleic acids, exosomes and microparticles", German Congress on Laboratory Medicine, Mannheim, Germany, September 2014

S Diederichs: "Long non-coding RNAs in Cancer" ESF / EMBO Meeting on non-coding RNA 2014, Pultusk, Polen, September 2014 (co-organizer)

S Diederichs: "Long non-coding RNA & Cancer" 23rd Biennial Congress of the European Association for Cancer Research (EACR), Munich, July 2014

S Diederichs: "Long non-coding RNA & Cancer" Max-Planck-Institute for Molecular Genetics, Berlin, Germany, June 2014

S Diederichs: "Long non-coding RNAs in Cancer" "Non-coding RNA - From Basic Mechanisms to Cancer", Heidelberg, Germany, June 2014 (co-organizer)

S Diederichs: "Long non-coding RNA & Cancer" EMBL, Galway, Ireland, June 2014

S Diederichs: "Long non-coding RNA & Cancer" University Vienna, Vienna, Austria, April 2014

S Diederichs: "The dark matter of the genome: Long non-coding RNA & Cancer" Medical University Graz, Graz, Austria, April 2014

S Diederichs: "Long non-coding RNAs in Cancer" 8th Graduate School Meeting "Cell Dynamics and Disease" Münster, April 2014

S Diederichs: " Long non-coding RNA & Cancer" Excellence Cluster CECAD Minisymposium, Cologne, April 2014

S Diederichs: "Long non-coding RNA in Cancer" Genomics Research Europe 2013, Barcelona, Spain, October 2013

S Diederichs: "Long non-coding RNA in Cancer" Institut d´Investigacío Biomèdica de Bellvitge (IDIBELL), Barcelona, Spain, October 2013

S Diederichs: "Nicht-kodierende RNA" GPOH (Gesellschaft für Pädiatrische Onkologie und Hämatologie) 2. Nachwuchsakademie "Pädiatrische Onkologie", Bad Godesberg, Juli 2013

S Diederichs: "Long non-coding RNAs & Cancer", International Union of Physiological Sciences (IUPS) 2013, Birmingham, United Kingdom, July 2013

S Diederichs: " Long non-coding RNA profiling identifies novel oncogenes and therapy response genes in lung cancer" 97. Jahrestagung der Deutschen Gesellschaft für Pathologie, Heidelberg, May 2013

Tony Gutschner: "The non-coding RNA MALAT1 is a critical regulator of lung cancer metastasis"  97. Jahrestagung der Deutschen Gesellschaft für Pathologie, Heidelberg, May 2013

Monika Hämmerle: "Characterization of long non-coding RNAs in hepatocellular carcinoma"  97. Jahrestagung der Deutschen Gesellschaft für Pathologie, Heidelberg, May 2013

S Diederichs: "microRNA Biogenesis, RNAi & long ncRNAs in Cancer" VIB Leuven Symposium "Non-coding Genomic: from Dark Matter to `Golden Secret´", Leuven, Belgium, April 2013 (keynote speaker)

S Diederichs: "The long non-coding RNA landscape of cancer" EMBO Practical Course "Analysis of small non-coding RNAs: From discovery to function",Heidelberg, Germany, April 2013

S Diederichs: "microRNAs and long non-coding RNAs in cancer" Universitätsklinikum Freiburg, April 2013

S Diederichs: "The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model" American Association for Cancer Research (AACR), "Annual Meeting 2013", Washington, USA, April 2013

S Diederichs: "Long non-coding RNA in cancer" National Institutes of Health, Bethesda, USA, April 2013 

S Diederichs: "Long non-coding RNA in cancer" International Joint Meeting of the German Society for Cell Biology (DGZ) and the German Society for Developmental Biology (GfE),  Heidelberg, Germany, March 2013 (chair)

S Diederichs: "The role of long non-coding RNA in lung cancer" Integrated Biobank of Luxembourg (IBBL)/Partnership for Personalized Medicine (PPM),"Lung Cancer Treatment in the Era of Personalized Medicine", Luxembourg, March 2013

S Diederichs: "MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model" Keystone Symposia on Molecular and Cellular Biology, "Noncoding RNAs in Development and Cancer", Vancouver, Canada, January 2013

S Diederichs: "Non-coding RNA & Cancer" Institut Curie, 2nd Course On Non-Coding Genome - 2012, Paris, France, December 2012

S Diederichs: "Non-coding RNAs, Cancer and Genome Editing" Karlsruher Institut für Technologie/Institute of Toxicology and Genetics, Karlsruhe, Germany, November 2012

S Diederichs: "Non coding RNA" German Society of Pathology (DGP) Nachwuchsakademie, Eberbach, Germany, October 2012

S Diederichs: "The non-coding RNA MALAT1 is a critical gene regulator for lung cancer metastasis in a novel human knockout model" GBM Study Group RNA Biochemistry, Bonn, Germany, October 2012

S Diederichs: "microRNA biogenesis & long non-coding RNAs in Cancer" Cancer Research UK, London, United Kingdom, September 2012

S Diederichs: "Argonautes, microRNA, Biogenesis&RNA Interference" Genomics Research Europe, Frankfurt, Germany, September 2012

S Diederichs: "Non-coding RNA - A whole new world of potential diagnostic and prognostic markers" Next Generation Molecular Diagnostics 2012, Prague, Czech Republic, June 2012
 
M Hämmerle, T Gutschner, M Polycarpou-Schwarz, C Hildenbrand, K Breuhahn, T Longerich, P Schirmacher, S Diederichs: "Molecular and functional analysis of long non-coding RNAs in hepatocellular carcinoma" German Society of Pathology (DGP), Berlin, Germany, May 2012

T Gutschner, M Eißmann, M Hämmerle, M Baas, C Hildenbrand, M Groß, M Zörnig, S Diederichs: "MALAT1 is essential for lung cancer metastasis in a novel human knockout model" German Society of Pathology (DGP), Berlin, Germany, May 2012

S Diederichs: "microRNAs & long non-coding RNAs in Cancer" EMBL Course "Analysis of short non-coding RNA", Heidelberg, Germany, April 2012

S Diederichs: "The many roles of Argonaute proteins in microRNA Biogenesis and RNA interference" Genomics Research 2012, Boston, USA, April 2012
 
S Diederichs: "microRNA Biogenesis, long non-coding RNA & Cancer" Yale University, New Haven, USA, April 2012

S Diederichs: "microRNA Biogenesis & long non-coding RNA in Cancer" Memorial Sloan-Kettering Cancer Center, New York, USA, April 2012

S Diederichs: "microRNA Biogenesis & long non-coding RNA in Cancer" University of Utah, Salt Lake City, USA, April 2012

S Diederichs: "microRNA & Cancer" American Association for Cancer Research (AACR), Chicago, USA, April 2012 (chair)

S Diederichs: "The non-coding RNA Landscape of Lung, Liver and Breast Cancer" Keystone Meeting: Non-coding RNAs, Snowbird, USA, April 2012
 
S Diederichs: "microRNA & long non-coding RNA in Cancer" German Society of Cell Biology (DGZ) - Award Lecture, Dresden, Germany, March 2012

S Diederichs: "microRNA, RNAi and long non-coding RNA in Cancer" Tel Aviv University, Tel Aviv, Israel, March 2012

M Hämmerle: "Non-coding RNA in malignant tumors: A new world of tumor biomarkers and target structures in cancer cells" German Society for Endocrinology (DGE), Mannheim, Germany, March 2012
 
S Diederichs: "Long non-coding RNAs & Cancer" X-GEN Targeting Non-Coding RNA, San Diego, USA, March 2012
 
S Diederichs: "The big world of small RNAs and the small world of big RNAs in Cancer" Lectio Magistralis, University of Trento, Italy, February 2012
 
T Gutschner: "Non-coding RNAs and Cell Cycle Regulation - Regulating the Regulator" Heidelberg Forum for Young Life Scientists, Heidelberg, Germany, February 2012

S Diederichs: "Long Non-coding RNA in the nucleus" Epigenetics @ DKFZ, Heidelberg, Germany, January 2012

S Diederichs: "Knocking out noncoding RNAs in human cancer" EMBL Symposium "Zinc Finger Nucleases", Heidelberg, Germany, December 2011
 
S Diederichs: "microRNA, non-coding RNA & Cancer" SFB 902, University of Frankfurt, Frankfurt, Germany, November 2011

S Diederichs: "Non-coding RNA - A whole new world of potential Biomarkers" Molecular Diagnostics of Cancer, Hannover, Germany, October 2011
 
S Diederichs: "Non-coding RNA in Liver Cancer" Visceral Medicine 2011 (DGVS / DGAV), Leipzig, Germany, September 2011
 
S Diederichs: "Long non-coding RNA in Cancer" 12th Young Scientist Meeting of the German Society of Cell Biology (DGZ): "RNA & Disease", Jena, Germany, September 2011 (organizer)

S Diederichs: "Non-coding RNA as molecular marker and functional player in Lung Adenocarcinoma" German Society of Pathology (DGP), Leipzig, Germany, June 2011

M Hämmerle, M Polycarpou-Schwarz, T Gutschner, C Hildenbrand, T Longerich, P Schirmacher, S Diederichs: "Non-coding RNA profiling in hepatocellular carcinoma" German Society of Pathology (DGP), Leipzig, Germany, June 2011

S Diederichs: "microRNA Biogenesis, RNAi and long non-coding RNA in Cancer" University of Calgary, Canada, June 2011

S Diederichs: "microRNA Biogenesis, RNAi and long non-coding RNA in Cancer" University of Lethbridge, Canada, June 2011

S Diederichs: "Small and Long non-coding RNAs in Cancer" International Graduate School for Molecular Medicine, University of Ulm, Germany, April 2011

S Diederichs: "microRNA Biogenesis, RNA interference & Non-coding RNAs in Cancer" University of Regensburg, Germany, February 2011

S Diederichs: "Long non-coding RNAs in the nucleus" Epigenetics @ DKFZ, Heidelberg, Germany, January 2011

S Diederichs: "microRNA Biogenesis, RNA interference & Long Non-coding RNA in Cancer" University of Münster, Germany, December 2010

S Diederichs: "MicroRNA and non-coding RNA in Breast Cancer" COMBATing Breast Cancer, Frankfurt, Germany, November 2010
 
S Diederichs: "Non-coding RNA & Cancer" Max-Delbrück-Center for Molecular Medicine & Berlin Institute for Systems Biology, Berlin, Germany, October 2010

S Diederichs: "microRNA Biogenesis, RNAi & long non-coding RNA in Cancer" SFB571 Seminar, Helmholtz Center Munich, Germany, October 2010

S Diederichs: "Non-coding RNA & Cancer" Mainz Genomics Seminar, Mainz, Germany, October 2010

M Polycarpou-Schwarz, T Gutschner, S Domcke, E Fiskin, M Geigges, J Rom, S Aulmann, P Sinn, S Diederichs: "Long non-coding RNA in Cancer" German Society for Biochemistry and Molecular Biology (GBM) - Study Group RNA Biochemistry, Pforzheim, Germany, October 2010

S Diederichs: "Non-coding RNA: Biomarkers and functional players in Cancer" Systems Genomics 2010, Heidelberg, Germany, September 2010

S Diederichs: "Using Zinc Finger Nucleases in Non-Coding RNA Biology" First European Symposium on Zinc Finger Nucleases, BRIC, Copenhagen, Denmark, September 2010
 
S Diederichs: "Using Zinc Finger Nucleases in Non-Coding RNA Biology" RNAi & miRNA Europe, Dublin, Ireland, September 2010
 
S Diederichs: "Beyond Proteins: Non-coding RNAs as Biomarkers in Cancer" International Society of Oncology and BioMarkers (ISOBM), Munich, Germany, September 2010
 
T Gutschner, M Polycarpou-Schwarz, J Rom, S Aulmann, P Schirmacher, P Sinn, S Diederichs: "Non-coding RNA - A new world beyond proteins of Tumor Markers and Regulators ?" German Society of Pathology (DGP), Berlin, Germany, May 2010

S Diederichs: "Beyond proteins - Non-coding RNA, microRNA & RNA interference in Cancer” German Research Foundation (DFG) - Hinterzartener Kreis, Cadenabbia - Lago di Como, Italy, May 2010
 
S Diederichs: "Argonaute proteins in microRNA Biogenesis & RNA interference" German Society for Cell Biology (DGZ), Regensburg, Germany, March 2010
 
S Diederichs: "MicroRNA Biogenesis & Regulation" DKFZ-Israel Summer School, Ein Gedi, Israel, November 2009
 
S Diederichs: "Argonaute-2 Co-Expression Enhances RNA Interference" RNAi Europe, Berlin, Germany, September 2009
 
S Diederichs: "Argonaute proteins in microRNA Biogenesis & RNA interference" Seminar Series - University Hospital Ulm, Ulm, Germany, September 2009

S Diederichs: "Argonaute proteins in microRNA Biogenesis & RNA interference" DFG Graduate College: Transcription, Chromatin & DNA Repair, Dormagen, Germany, April 2009
 
S Diederichs: "Argonaute proteins in microRNA Biogenesis & RNA interference" Medical University Hannover (MHH), Hannover, Germany, January 2009

S Diederichs: "Argonaute proteins in microRNA Biogenesis & RNA interference" Molecular Cell Biology Kolloquium, University of Lübeck, Lübeck, Germany, November 2008

S Diederichs: "microRNA Biology, RNAi & Cancer" Scientific Seminar, Institute of Pathology, University of Heidelberg, Heidelberg, Germany, November 2008

S Diederichs: "Argonaute proteins in microRNA Processing and Regulation" GBM Study Group RNA Biochemistry Meeting, Kassel, Germany, September 2008
 
S Diederichs: "Dual Role for Argonaute Proteins in microRNA Processing" RNAi Europe Meeting, Stockholm, Sweden, September 2008
 
S Diederichs, DA Haber: "Dual Role for Argonaute Proteins in microRNA Processing and Post-Transcriptional Regulation of microRNA Expression" RNAi World Meeting, Boston, MA, May 2008
 
S Diederichs: "Argonaute Proteins in microRNA Processing and Regulation" Sixth International RNAi & microRNAs Meeting, Boston, MA, April 2008
 
S Diederichs, DA Haber: "Argonaute proteins in microRNA biogenesis" Miami Winter Symposium "Regulatory RNA in Biology and human Health", Miami, FL, February 2008

S Diederichs: "Argonaute proteins & microRNA biogenesis" Blue Seminar Series, European Molecular Biology Laboratory (EMBL), Heidelberg, December 2007

S Diederichs: "Argonaute proteins, microRNA biogenesis & RNA interference" German Cancer Research Center (DKFZ), Heidelberg, December 2007

S Diederichs: "Argonaute proteins & microRNA processing" Max-Planck-Institute for Biophysical Chemistry, Göttingen, December 2007

S Diederichs, DA Haber: "Dual Role for Argonaute proteins in microRNA Processing and Post-Transcriptional Regulation of microRNA Expression" AACR Special Conference "The role of Non-Coding RNAs in Cancer", Cambridge, MA, November 2007 [This presentation was selected for a 2007 AACR Scholar-in-Training Award. ]

S Diederichs
, DA Haber: "Dual role for Argonaute proteins in microRNA processing and regulation" Society for Biochemistry and Molecular Biology (GBM), Hamburg, Germany, September 2007

S Diederichs, DA Haber: "Two novel functions for Argonaute proteins in microRNA Processing and Regulation" Cancer Program Meeting of the Broad Institute of Harvard and MIT, Cambridge, MA, July 2007

S Diederichs: "Two novel functions for Argonaute proteins in microRNA Processing" 2nd microSymposium on small RNAs, Vienna, Austria, May 2007

S Diederichs: "Cancer Research: At the Interface of Medicine and Molecular Biology" German National Academic Merit Foundation Symposium “Future and Frontiers of Research”, Cambridge, MA, January 2007

S Diederichs, N Bäumer, M Möller, S Agrawal, S Pierschalski, WE Berdel, H Serve, C Müller-Tidow: "INCA1 is a novel growth-suppressive CDK inhibitor that blocks B-Myb and E2F activity and is lost in tumors" Annual Meeting German Society for Hematology and Oncology (DGHO), 2004; Onkologie (2004) 27 (S3): 59

S Diederichs, P Ji, R Metzger, S Klümpen, M Möller, PM Schneider, WE Berdel, H Serve, C Müller-Tidow: "Comparative genome-wide analysis of metastasis-associated genes in early-stage non-small cell lung cancer (NSCLC) using high-density oligonucleotide microarray technology" Annual Meeting German Society for Hematology and Oncology (DGHO), 2002; Onkologie (2002) 25 (S4): 139



Asterisks (*) indicate shared first or last or corresponding authorship.
Authors in bold are present or former members of our division "RNA Biology & Cancer".
If multiple authors are listed, the presenting author is underlined.

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