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Selected Publications

1.         Lachmann, S.; Bar, S.; Rommelaere, J.; Nuesch, J.P. Parvovirus interference with intracellular signalling: mechanism of PKCeta activation in MVM-infected A9 fibroblasts. Cell Microbiol 2008, 10, 755-769, doi:10.1111/j.1462-5822.2007.01082.x.

2.         Nuesch, J.P.; Bar, S.; Lachmann, S.; Rommelaere, J. Ezrin-radixin-moesin family proteins are involved in parvovirus replication and spreading. J Virol 2009, 83, 5854-5863, doi:10.1128/JVI.00039-09.

3.         Bar, S.; Rommelaere, J.; Nuesch, J.P. PKCeta/Rdx-driven phosphorylation of PDK1: a novel mechanism promoting cancer cell survival and permissiveness for parvovirus-induced lysis. PLoS Pathog 2015, 11, e1004703, doi:10.1371/journal.ppat.1004703.

4.         Nuesch, J.P.; Lacroix, J.; Marchini, A.; Rommelaere, J. Molecular pathways: rodent parvoviruses--mechanisms of oncolysis and prospects for clinical cancer treatment. Clin Cancer Res 2012, 18, 3516-3523, doi:10.1158/1078-0432.CCR-11-2325.

5.         Nuesch, J.P.; Rommelaere, J. Tumor suppressing properties of rodent parvovirus NS1 proteins and their derivatives. Adv Exp Med Biol 2014, 818, 99-124, doi:10.1007/978-1-4471-6458-6_5.

6.         Nuesch, J.P.; Lachmann, S.; Rommelaere, J. Selective alterations of the host cell architecture upon infection with parvovirus minute virus of mice. Virology 2005, 331, 159-174, doi:10.1016/j.virol.2004.10.019.

7.         Nuesch, J.P.; Rommelaere, J. NS1 interaction with CKII alpha: novel protein complex mediating parvovirus-induced cytotoxicity. J Virol 2006, 80, 4729-4739, doi:10.1128/JVI.80.10.4729-4739.2006.

8.         Nuesch, J.P.; Rommelaere, J. A viral adaptor protein modulating casein kinase II activity induces cytopathic effects in permissive cells. Proc Natl Acad Sci U S A 2007, 104, 12482-12487, doi:10.1073/pnas.0705533104.

9.         Bar, S.; Daeffler, L.; Rommelaere, J.; Nuesch, J.P. Vesicular egress of non-enveloped lytic parvoviruses depends on gelsolin functioning. PLoS Pathog 2008, 4, e1000126, doi:10.1371/journal.ppat.1000126.

10.        Bar, S.; Rommelaere, J.; Nuesch, J.P. Vesicular transport of progeny parvovirus particles through ER and Golgi regulates maturation and cytolysis. PLoS Pathog 2013, 9, e1003605, doi:10.1371/journal.ppat.1003605.

11.        Witzigmann, D.; Grossen, P.; Quintavalle, C.; Lanzafame, M.; Schenk, S.H.; Tran, X.T.; Englinger, B.; Hauswirth, P.; Grunig, D.; van Schoonhoven, S., et al. Non-viral gene delivery of the oncotoxic protein NS1 for treatment of hepatocellular carcinoma. J Control Release 2021, 334, 138-152, doi:10.1016/j.jconrel.2021.04.023.

12.        Neulinger-Munoz, M.; Schaack, D.; Grekova, S.P.; Bauer, A.S.; Giese, T.; Salg, G.A.; Espinet, E.; Leuchs, B.; Heller, A.; Nuesch, J.P.F., et al. Human Retrotransposons and the Global Shutdown of Homeostatic Innate Immunity by Oncolytic Parvovirus H-1PV in Pancreatic Cancer. Viruses 2021, 13, doi:10.3390/v13061019.

13.        Claudia Tessmer 1, C.P., Jana Fees 2, Hendrik Welsch 2, Rebecca Eudenbach 2, Martin Faber 2,; Alicia Simón 2, A.A., Jean Rommelaere 3, Ilse Hofmann 1 and Jürg P. F. Nüesch 2,*. Generation and Validation of Monoclonal Antibodies Suitable for Detecting and Monitoring Parvovirus Infections. Pathogens 2022, 2022 11.


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