Publications since 2010

Bossler F, Kuhn BF, Günther T, Kraemer SJ, Khalkar P, Adrian S, Lohrey C, Holzer A, Shimobayashi M, Dürst M, Mayer A, Rösl F, Grundhoff A, Krijgsveld J, Hoppe-Seyler K, Hoppe-Seyler F (2019).
Repression of Human Papillomavirus Oncogene Expression under Hypoxia is Mediated by PI3K/mTORC2/AKT Signaling.
mBIO, 10: e02323-18.

Lien YH, Mahato, DR, Hoppe-Seyler F, Fischer WB (2019)
Membrane partitioning of peptide aggregates - coarse grained molecular dynamics simulations.
J. Biomol. Struct. Dynam., in press

Hoppe-Seyler K, Bossler F, Braun JA, Herrmann AL, Hoppe-Seyler F. (2018).
The HPV E6/E7 Oncogenes: Key Factors for Viral Carcinogenesis and Therapeutic Targets.
Trends in Microbiology, 26: 158-168.

Honegger A, Schilling D, Sültmann H, Hoppe-Seyler K, Hoppe-Seyler F. (2018).
Identification of E6/E7-dependent microRNAs in HPV-positive cancer cells.
Methods in Molecular Biology, 1699: 119-134.

Hoppe-Seyler K, Honegger, A., Bossler F, Sponagel J, Bulkescher J, Lohrey C, Hoppe-Seyler F. (2017).
Viral E6/E7 Oncogene and Cellular Hexokinase 2 Expression in HPV-Positive Cancer Cell Lines.
Oncotarget 8, 106342-106332

Hoppe-Seyler K, Mändl J, Adrian S, Kuhn BJ, Hoppe-Seyler F. (2017).
Virus/Host Cell Crosstalk in Hypoxic HPV-Positive Cancer Cells.
Viruses 9:pii: E174.

Hoppe-Seyler K, Bossler B, Lohrey C, Bulkescher J, Rösl F , Jansen L, Mayer A, Vaupel P, Dürst M, Hoppe-Seyler F. (2017).
Induction of dormancy in hypoxic human papillomavirus-positive cancer cells.
Proc. Natl. Acad. Sci. U. S. A. 114:E990-E998.

Honegger A, Schilling D, Bastian S, Sponagel J, Kuryshev V, Sültmann H, Scheffner M, Hoppe-Seyler K, Hoppe-Seyler F. (2015).
Dependence of intracellular and exosomal microRNAs on viral E6/E7 oncogene expression in HPV-positive tumor cells.
PLoS Pathog 11:e1004712.

Stutz C, Reinz E, Honegger A, Bulkescher J, Schweizer J, Zanier K, Travé G, Lohrey C, Hoppe-Seyler K, Hoppe-Seyler F. (2015).
Intracellular analysis of the interaction between the human papillomavirus type 16 E6 oncoprotein and inhibitory peptides.
PLoS ONE 10:e0132339.

Leitz J, Reuschenbach M, Lohrey C, Honegger A, Accardi R, Tommasino M, Llano M, von Knebel Doeberitz M, Hoppe-Seyler K, Hoppe-Seyler F. (2014).
Oncogenic human papillomaviruses activate the tumor-associated lens epithelial-derived growth factor (LEDGF) gene.
PLoS Pathog 10:e1003957.

Zanier K, Stutz C, Kintscher S, Reinz E, Sehr P, Bulkescher J, Hoppe-Seyler K, Travé G, Hoppe-Seyler F. (2014).
The E6AP binding pocket of the HPV16 E6 oncoprotein provides a docking site for a small inhibitory peptide unrelated to E6AP, indicating druggability of E6.
PLoS ONE 9:e112514.

Honegger A, Leitz J, Bulkescher J, Hoppe-Seyler K, Hoppe-Seyler F. (2013).
Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and the amounts of extracellular microvesicles released from HPV-positive cancer cells.
Int J Cancer 133:1631-42.

Wagener N, Bulkescher J, Macher-Goeppinger S, Karapanagiotou-Schenkel I, Hatiboglu G, Abdel-Rahim M, Abol-Enein H, Ghoneim MA, Bastian PJ, Müller SC, Haferkamp A, Hohenfellner M, Hoppe-Seyler F, Hoppe-Seyler K. (2013).
Endogenous BTG2 expression stimulates migration of bladder cancer cells and correlates with poor clinical prognosis for bladder cancer patients.
Br J Cancer 108:973-82.

Hoppe-Seyler K, Sauer P, Lohrey C, Hoppe-Seyler F. (2012).
The inhibitors of nucleotide biosynthesis leflunomide, FK778, and mycophenolic acid activate hepatitis B virus replication in vitro.
Hepatology 56: 9-16.

Fussbroich B, Wagener N, Macher-Goeppinger S, Benner A, Fälth M, Sültmann H, Holzer A, Hoppe-Seyler K, Hoppe-Seyler, F. (2011).
EZH2 depletion blocks the proliferation of colon cancer cells.
PLoS ONE 6:e21651

Laurenson S, Pett MR, Hoppe-Seyler K, Denk C, Hoppe-Seyler F, Coleman N, Ko Ferrigno P. (2011).
Development of peptide aptamer microarrays for detection of HPV16 oncoproteins in cell extracts.
Anal Biochem 410:161-70

Hoppe-Seyler F, Hoppe-Seyler K. (2011).
Emerging topics in human tumor virology.
Int J Cancer 129:1289-99.

Crnkovic-Mertens I, Bulkescher J, Mensger N, Hoppe-Seyler F, Hoppe-Seyler K. (2010).
Isolation of peptides blocking the function of the anti-apoptotic Livin protein.
Cell Mol Life Sci 11:1895-905.

Mern DS, Hoppe-Seyler K, Hoppe-Seyler F, Hasskarl J, Burwinkel B. (2010).
Targeting Id1 and Id3 by a specific peptide aptamer induces E-box promoter activity, cell cycle arrest, and apoptosis in breast cancer cells.
Breast Cancer Res Treat 124:623-33.

Moosmeier MA, Bulkescher J, Hoppe-Seyler K, Hoppe-Seyler F. (2010).
Binding proteins internalized by PTD-fused ligands allow the intracellular sequestration of selected targets by ligand exchange.
Int. J Mol Med 25:557-64.

Wagener N, Macher-Goeppinger S, Pritsch M, Hüsing J, Hoppe-Seyler K, Schirmacher P, Pfitzenmaier J, Haferkamp A, Hoppe-Seyler F, Hohenfellner M. (2010).
Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma.
BMC Cancer 10:524.

Moosmeier MA, Bulkescher J, Reed J, Schnölzer M, Heid H, Hoppe-Seyler K, Hoppe-Seyler F. (2010).
Transtactin: a universal transmembrane delivery system for Strep-tag II-fused cargos.
J Cell Mol Med 14:1935-45.

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