Research
- Research Topics
- Cell Biology and Tumor Biology
- Stem Cells and Cancer
- Inflammatory Stress in Stem Cells
- Experimental Hematology
- Molecular Embryology
- Signal Transduction and Growth Control
- Epigenetics
- Redox Regulation
- Vascular Oncology and Metastasis
- Clinical Neurobiology
- Molecular Neurogenetics
- Chaperones and Proteases
- Vascular Signaling and Cancer
- Molecular Neurobiology
- Mechanisms Regulating Gene Expression
- Molecular Biology of Centrosomes and Cilia
- Dermato-Oncology
- Pediatric Leukemia
- Tumour Metabolism and Microenvironment
- Personalized Medical Oncology
- Molecular Hematology - Oncology
- Cancer Progression and Metastasis
- Translational Surgical Oncology
- Neuronal Signaling and Morphogenesis
- Cell Signaling and Metabolism
- Cell Fate Engineering and Disease Modeling
- Cancer Drug Development
- Cell Morphogenesis and Signal Transduction
- Functional and Structural Genomics
- Molecular Genome Analysis
- Molecular Genetics
- Pediatric Neurooncology
- Cancer Genome Research
- Chromatin Networks
- Functional Genome Analysis
- Theoretical Systems Biology
- Neuroblastoma Genomics
- Signaling and Functional Genomics
- Signal Transduction in Cancer and Metabolism
- RNA Biology and Cancer
- Systems Biology of Signal Transduction
- Molecular thoracic Oncology
- Proteomics of Stem Cells and Cancer
- Computational Genomics and System Genetics
- Applied Functional Genomics
- Applied Bioinformatics
- Translational Medical Oncology
- Metabolic crosstalk in cancer
- Pediatric Glioma Research
- Cancer Epigenomics
- Translational Pediatric Sarcoma Research
- Artificial Intelligence in Oncology
- Mechanisms of Genomic Variation and Data Science
- Neuropathology
- Pediatric Oncology
- Neurooncology
- Somatic Evolution and Early Detection
- Translational Control and Metabolism
- Soft-Tissue Sarcoma
- Precision Sarcoma Research
- Brain Mosaicism and Tumorigenesis
- Mechanisms of Genome Control
- Translational Gastrointestinal Oncology and Preclinical Models
- Translational Lymphoma Research
- Mechanisms of Leukemogenesis
- Genome Instability in Tumors
- Developmental Origins of Pediatric Cancer
- Brain Tumor Translational Targets
- Translational Functional Cancer Genomics
- Regulatory Genomics and Cancer Evolution
- SPRINT
- Cancer Risk Factors and Prevention
- Cancer Epidemiology
- Biostatistics
- Clinical Epidemiology and Aging Research
- Health Economics
- Physical Activity, Prevention and Cancer
- Preventive Oncology
- Personalized Early Detection of Prostate Cancer
- Digital Biomarkers for Oncology
- Genomic Epidemiology
- Cancer Survivorship
- Immunology and Cancer
- Cellular Immunology
- Molecular Oncology of Gastrointestinal Tumors
- Immunoproteomics
- T Cell Metabolism
- Personalized Immunotherapy
- mRNA Cancer Immunotherapies
- Translational Immunotherapy
- B Cell Immunology
- Immune Diversity
- Structural Biology of Infection and Immunity
- Applied Tumor Immunity
- Neuroimmunology and Brain Tumor Immunology
- Adaptive Immunity and Lymphoma
- Immune Regulation in Cancer
- Systems Immunology and Single Cell Biology
- GMP & T Cell Therapy
- Immune Monitoring
- News
- Imaging and Radiooncology
- Radiology
- Research
- Computational Radiology Research Group
- Contrast Agents In Radiology Research Group
- Neuro-Oncologic Imaging Research Group
- Radiological Early Response Assessment Of Modern Cancer Therapies
- Imaging In Monoclonal Plasma Cell Disorders
- 7 Tesla MRI - Novel Imaging Biomarkers
- Functional Imaging
- Visualization And Forensic Imaging
- PET/MRI
- Dual- and Multienergy CT
- Radiomics Research Group
- Prostate Research Group
- Breast Imaging Research Group
- Bone marrow
- Musculoskeletal Imaging
- Microstructural Imaging Research Group
- Staff
- Patients
- Research
- Medical Physics in Radiology
- X-Ray Imaging and Computed Tomography
- Federated Information Systems
- Translational Molecular Imaging
- Medical Physics in Radiation Oncology
- Biomedical Physics in Radiation Oncology
- Intelligent Medical Systems
- Medical Image Computing
- Radiooncology - Radiobiology
- Radiation Oncology
- Molecular Radiooncology
- Nuclear Medicine
- Translational Radiation Oncology
- Molecular Biology of Systemic Radiotherapy
- Interactive Machine Learning
- Multiparametric methods for early detection of prostate cancer
- Molecular Mechanisms of Head and Neck Tumors
- Radiology
- Infection, Inflammation and Cancer
- Tumor Virology
- Viral Transformation Mechanisms
- Pathogenesis of Virus-Associated Tumors
- Immunotherapy and Immunoprevention
- Applied Tumor Biology
- Virotherapy
- Virus-associated Carcinogenesis
- Chronic Inflammation and Cancer
- Microbiome and Cancer
- Cell Plasticity and Epigenetic Remodeling
- Experimental Hepatology, Inflammation and Cancer
- Infections and Cancer Epidemiology
- Tumorvirus-specific Vaccination Strategies
- Mammalian Cell Cycle Control Mechanisms
- Molecular Therapy of Virus-Associated Cancers
- DNA Vectors
- Episomal-Persistent DNA in Cancer- and Chronic Diseases
- Cell Biology and Tumor Biology
- Research Groups A-Z
- Junior Research Groups
- Core Facilities
- Center for Preclinical Research
- Chemical Biology Core Facility
- Electron Microscopy
- Flow Cytometry
- Genomics and Proteomics
- Information Technology
- Library
- Kataloge -- Catalogues
- Zeitschriften - Journals
- E-Books - ebooks
- Datenbanken - Databases
- Dokument-Lieferung - Document Delivery
- Publikationsdatenbank - Publication database
- DKFZ Archiv - DKFZ Archive
- Open Access
- Science 2.0
- Ansprechpartner - Contact
- More Information - Service
- Anschrift - Address
- Antiquariat - Second Hand
- Aufstellungssystematik - Shelf Classification
- Ausleihe - Circulation
- Benutzerhinweise - Library Use
- Beschaffungsvorschläge - Desiderata
- Fakten und Zahlen - Facts and Numbers
- Kooperationen, Konsortien - Cooperations, Consortia
- Kopieren, Scannen - Copying, Scans
- Kurse, Führungen - Courses, Introductions
- DKFZ-Intern - internal only
- DEAL-Info
- Light Microscopy
- Omics IT and Data Management Core Facility
- Small Animal Imaging
- Metabolomics Core Technology Platform
- Data Science @ DKFZ
- INFORM
- Baden-Württemberg Cancer Registry
- Cooperations & Networks
- National Cooperations
- International Cooperations
- Cooperational Research Program with Israel: DKFZ - MOST in Cancer Research
- Program
- Members of the Program Committee
- Call
- Publication Database
- German-Israeli Cancer Research Schools
- Archive
- Heidelberg - Israel, Science and Culture
- Symposium 40 Years of German-Israeli Cooperation
- 35th Anniversary Symposium
- 34th Meeting of the DKFZ-MOST Program
- 40th Anniversary Publication
- 30th Anniversary Publication
- 20th Anniversary Publication
- Flyer - The Cancer Cooperation Program
- List Publications 1976-2004
- Highlight-Projects
- Cooperational Research Program with Israel: DKFZ - MOST in Cancer Research
- Cooperations with industrial companies
- DKFZ PostDoc Network
- Cross Program Topic RNA@DKFZ
- Cross Program Topic Epigenetics@dkfz
- Cross Program Topic Single Cell Sequencing
- WHO Collaborating Centers
- DKFZ Site Dresden
- Health + Life Science Alliance Heidelberg Mannheim
Cancer Genome Research
Head: Prof. Dr. Holger Sültmann
Senior Scientists and Postdocs: PD Dr. Sabine Klauck, Dr. Arlou Kristina Angeles, Dr. Ann-Kathrin Daum, Dr. Florian Janke, Dr. Fawaz Al-Shaheri, Dr. Astrid Laut
Prof. Dr. Petros Christopoulos (Thoraxklinik Heidelberg)
Dr. Anja Riediger, Dr. Samaneh Eickelschulte (Clinical Cooperation Unit "Multiparametric Methods for the Detection of Prostate Cancer", DKFZ and Urological Clinic Heidelberg)
Dr. Andrey Turchinovic (Heidelberg Biolabs)
PhD students: Myesha Jahin, Mateo Gasser, Ana Rodríguez Ces (University of Santiago de Compostela), Philippe Decruyenaere (Ghent University)
MSc student: Emma Brkic
Technical assistants: Sabrina Gerhardt, Simon Ogrodnik
Contact:
Prof. Dr. rer. nat. Holger Sültmann
DKFZ and NCT Heidelberg
Im Neuenheimer Feld 460
69120 Heidelberg, Germany
Tel.: ++49 6221 565934
Fax: ++49 6221 565382
E-Mail: h.sueltmann@dkfz.de
(Directions)
Cancer cells differ from normal cells by their microenvironment, altered (epi)genomes, as well as gene and protein expression. The characterization of such changes in tumors and tumor stages is essential for understanding the mechanisms of tumor progression and the definition of molecular markers for diagnosis and prognosis. Tumor heterogeneity in space and time determines therapy success and patient survival. Therefore, precision medicine approaches in cancer research need to address the following key questions:
- tumor risk stratification with multimodal biomarkers
- mechanisms of tumor progression and therapy failure
- therapy response prediction using noninvasive approaches.
Former group members:
Prof. Dr. Peter Altevogt, Dr. Simone Bauer, Dr. Chiara Dalle Fratte, Philipp Hecht, Dr. Steffen Dietz, Alessa Klär, Niclas Flosdorf, Louise Appenheimer, Saskia Müller, Enrico Black, Dr. Doreen Heckmann-Nötzel, Sebastian Weingart, Lisa Gu, Sabrina Müller, Dr. Leonie Ratz, Dr. Anja Riediger, Dr. Vladimir Kuryshev, Clementine Mercé, Dr. Julia Romic-Pickl, Dr. Sajo Kaduthanam, Dr. Uwe Schirmer, Daniel Reidenbach, Denise Keitel, Dr. Ruprecht Kuner, Dr. Helen Hülsmann, Dr. Holger Armbruster, Dr. Mark Laible, Dr. Daniela Wuttig, Dr. Julia Starmann, Jennifer Metzger, Marina Gonzalez, Dr. Lukasz Kacprzyk, Dr. Stephan Gade, Sara Myers, Dr. Maria Fälth, Tatjana Andrasiuk, Dr. Rainer Will, Dr. Marc Johannes, Dr. Jan Christoph Brase, Dr. Stephanie Wittig-Blaich, Dr. Melanie Bewerunge-Hudler, Rita Schatten, Angelika Wörner, Thorsten Kühlwein, Dr. Nicole Chui Pressinotti, Dr. Caroline End, Prof. Dr. Tim Beißbarth, Dr. Alberto Calabró, Dr. Mark Fellmann, Dr. Christian Löbke, Dr. Markus Ruschhaupt, Dr. Van Duc Luu, Dr. Michael Stojanov, Andreas Buneß, Dr. Claudia Heine, Prof. Dr. Holger Fröhlich, Prof. Dr. Achim Tresch, Dr. Jörg Schneider, Dr. Katharina Finis, Dr. Wolfgang Huber, Dr. Markus Vogt, Prof. Dr. Florian Haller, Gabi Rottsahl, Claudia Grosser
Support:
German Cancer Consortium (DKTK)
German Center for Lung Research (DZL)
German Federal Ministry for Science and Education (BMBF).
Bruno und Helene Jöster Stiftung
Heidelberg Institute for Personalized Oncology (HIPO)