Multiple myeloma

We have established and are leading the International Multiple Myeloma rESEarch (IMMEnSE) consortium, that brings together several international clinical and research institutions with the aim to investigate genetic epidemiology and pharmacogenetics of multiple myeloma (MM) in one of the largest populations of MM patients existing up to date. At present we have collected about 3,000 samples of cases and a similar number of controls. In this context we perform studies on susceptibility SNPs, both following a candidate gene approach and following up findings of genome-wide association studies (GWAS) in collaboration with various groups belonging to the InterLymph consortium, and studies on the impact of SNPs on response to treatment and survival.

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