Research Group Ion Beam Therapy (E0408)

Oliver Jäkel (in ch.)

Translational research for ion beam therapy

Our research group focuses on further exploiting and developing the potential of proton and ion beams in radiotherapy and translating its research projects into clinical applications. Our primary research partner is the Heidelberg Ion Beam Therapy Facility (HIT) at the University Hospital Heidelberg.

HIT is the first European hospital based facility for scanned proton and heavy ion radiotherapy and has started its operation in November 2009. The projects at DKFZ have gained extensive experience with this treatment modality within a pilot project at the German heavy ion research center Helmholtzzentrum für Schwerionenforschung GmbH (GSI) in Darmstadt between 1997 and 2008.

Current research topics

  • Dosimetry
    • Track-based, in-vivo assessment of physical and biological dose
    • Subcellular energy deposition and impact on biological response
    • Water calorimetry for ion beams
    • Experimental characterization and modeling of detector response
    • strong magnetic fields
  • New imaging modalities for treatment planning
    • Dual energy computed tomography
    • MR-guidance
    • Development of multi-modality phantoms

Selected publications

  • Möhler, C., Wohlfahrt, P., Richter, C. & Greilich, S. (2016), 'Range prediction for tissue mixtures based on dual-energy CT', Physics in Medicine and Biology 61(11), N268.
  • Klimpki, G., Mescher, H., Akselrod, M. S., Jäkel, O. & Greilich, S. (2016), ‘Fluence-based dosimetry of proton and heavier ion beams using single track detectors’, Physics in Medicine and Biology61(3), 1021-1040.
  • Niklas, M., Abdollahi, A., Akselrod, M. S., Debus, J., Jäkel, O., and Greilich, S. Subcellular spatial correlation of particle traversal and biological response in clinical ion beams. International Journal of Radiation Oncology*Biology*Physics, 2013, 87, 1141-1147.

For a full list of articles, theses etc. from the division, see here. For more information on publications related to the group's projects, see here.


Prof. Dr. Oliver Jäkel (in ch.)

phone: +49 6221 42-2420
fax:      +49 6221 42-2561

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