2021

Palm W. 2021. GOLPH3 tunes up glycosphingolipid synthesis for cell growth. EMBO J; e108070. doi: 10.15252/embj.2021108070

Palm W. 2021. Metabolic plasticity allows cancer cells to thrive under nutrient starvation. Proc Natl Acad Sci USA; 118:e2102057118. doi: 10.1073/pnas.2102057118

Prentzell MT, Rehbein U, Sandoval MC, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G, Genomics England Research Consortium, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kędra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Pittol JMR, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Stefan E, Teleman A, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov T, Zmorzynska J, Opitz CA, Thedieck K. 2021. The G3BP proteins tether the TSC complex to lysosomes and suppress mTORC1 signaling. Cell, 184:655-674. doi: 10.1016/j.cell.2020.12.024

2020

Palm W and Rodenfels J. 2020. Understanding the role of lipids and lipoproteins in development. Development, 147:dev186411. doi: 10.1242/dev.186411

King B, Araki J, Palm W, Thompson CB. 2020. Yap/Taz promote the scavenging of extracellular nutrients through macropinocytosis. Genes Dev, 34:1345-1358. doi: 10.1101/gad.340661.120

Haneke K, Schott J, Lindner D, Hollensen A, Damgaard C, Mongis C, Knop M, Palm W, Ruggieri A, Stoecklin G. 2020. CDK1 couples proliferation with protein synthesis. J Cell Biol 219:e201906147. doi: 10.1083/jcb.201906147

2018

Palm W. 2018. Metabolic functions of macropinocytosis. Phil Trans R Soc B 374: 20180147. doi: 10.1098/rstb.2018.0285

Redelman-Sidi G, Binyamin A, Gaeta I, Palm W, Thompson CB, Romesser PB, Lowe SW, Bagul M, Doench JG, Root DE, Glickman MS. 2018. The canonical Wnt pathway drives macropinocytosis in cancer. Cancer Res. 78:4658-4670. doi: 10.1158/0008-5472.CAN-17-3199

2017

Palm W, Araki J, King B, DeMatteo RG, Thompson CB. 2017. Critical role for PI3-kinase in regulating the use of proteins as an amino acid source. Proc Natl Acad Sci USA; 114:E8628-E8636. doi: 10.1073/pnas.1712726114

Palm W and Thompson CB. 2017. Nutrient acquisition strategies of mammalian cells. Nature; 546:234-242. doi: 10.1038/nature22379

Thompson CB and Palm W. 2017. Reexamining how cancer cells exploit the body's metabolic resources. Cold Spring Harb Symp Quant Biol. pii: 030734. doi: 10.1101/sqb.2016.81.030734

2016

Krishna S, Palm W, Lee Y, Yang W, Bandyopadhyay U, Xu H, Florey O, Thompson CB, Overholtzer M. 2016. PIKfyve regulates vacuole maturation and nutrient recovery following engulfment. Dev Cell; 38:536-47. doi: 10.1016/j.devcel.2016.08.001

Chio II, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Wilson J, Sangar V, Hao Y, Öhlund D, Wright K, Fillippi D, Lee EJ, Da Silva B, Schoepfer C, Wilkinson JE, Buscaglia J, DeNicola G, Tiriac H, Hammell M, Crawford H, Schmidt EE, Thompson CB, Pappin DJ, Sonenberg N, Tuveson DA. 2016. NRF2 directs redox-dependent mRNA translation in pancreatic cancer. Cell; 166:963-76. doi: 10.1016/j.cell.2016.06.056

2015

Ye J, Palm W, Peng M, King B, Lindsten T, Li MO, Koumenis C, Thompson CB. 2015. GCN2 sustains mTORC1 Suppression upon amino acid deprivation by inducing Sestrin2. Genes Dev; 29:2331-6. doi: 10.1101/gad.269324.115

Palm W, Park Y, Wright K, Pavlova NN, Tuveson DA, Thompson CB. 2015. The utilization of extracellular proteins as nutrients is suppressed by mTORC1. Cell; 162:259-70. doi: 10.1016/j.cell.2015.06.017

2013

Palm W, Swierczynska MM, Kumari, V, Ehrhart-Bornstein M, Bornstein SR, Eaton S. 2013. Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals. PLoS Biology; 11:e1001505. doi: 10.1371/journal.pbio.1001505

2012

Baer MM, Palm W, Eaton S, Leptin M, Affolter M. 2012. Microsomal triacylglycerol transfer protein (MTP) is required to expand tracheal lumen in Drosophila in a cell-autonomous manner. J Cell Sci; 15:6038-48. doi: 10.1242/jcs.110452

Carvalho M, Sampaio JL, Palm W, Brankatschk M, Eaton S, Shevchenko A. 2012. Effects of diet and development on the Drosophila lipidome. Mol Syst Biol; 8:600. doi: 10.1038/msb.2012.29

Palm W, Sampaio JL, Brankatschk M, Carvalho M, Mahmoud A, Shevchenko A, Eaton S. 2012. Drosophila lipoproteins – assembly, function, and influence on tissue lipid composition. PLoS Genetics; 8:e1002828. doi: 10.1371/journal.pgen.1002828

2010

Carvalho M, Schwudke D, Sampaio JL, Palm W, Riezman I, Dey G, Gupta GD, Mayor S, Riezman H, Shevchenko A, Kurzchalia TV, Eaton S. 2010. Survival strategies of a sterol auxotroph. Development; 137:3675-85. doi: 10.1242/dev.044560

2009

Palm W, Hockemeyer D, Kibe T, de Lange T. 2009. Functional dissection of human and mouse POT1 proteins. Mol Cell Biol; 29:471-82. doi: 10.1128/MCB.01352-08

2008

Palm W and de Lange T. 2008. How shelterin protects mammalian telomeres. Annu Rev Genet; 42:301-34. doi: 10.1146/annurev.genet.41.110306.130350

Hockemeyer D, Palm W, Wang RC, Couto SS, de Lange T. 2008. Engineered telomere degradation models dyskeratosis congenita. Genes Dev; 22:1773-85. doi: 10.1101/gad.1679208

2007

Hockemeyer D, Palm W, Else T, Daniels JP, Takai KK, Ye JZ, Keegan CE, de Lange T, Hammer GD. 2007. Telomere protection by mammalian POT1 requires interaction with TPP1. Nat Struct Mol Biol; 14:754-61. doi: 10.1038/nsmb1270

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