Translational image-guided RadioTherapy

Group leader: Prof. Dr. Oliver Jäkel (in ch.)

Summary

(a) Standard diagnostic setup: the patient lies on a foam mattress and the coil is located directly on the patient’s body. (b) Radiotherapy treatment setup: the patient lies on a flat table overlay, a leg and hip immobilisation device and a coil holder are used.
© dkfz.de

In our group we focus on investigating the potential of using multimodal (MRI, CT and PET) images for radiotherapy treatment planning of cancer patients, with a focus on prostate cancer. This is a field of study with many branches, such as adaptive treatment planning, dosimetry, MR optimization, CT optimization, pseudo CT development, attenuation correction and the use of anthropomorphic phantoms. In our group we focus on both the technical aspects of image-guided radiotherapy and establishing patient-oriented workflows.

These projects are part of a joint National-Center for Tumor Diseases (NCT)-funded Proof-of-Concept clinical study with the aim to integrate PET/MRI-data into radiotherapy treatment planning for patients with prostate cancer. As a part of this study, patient trials will be carried out in both Heidelberg and Dresden.

 

Current research topics

  • MR sequence optimization for Radiotherapy
  • Stopping power prediction for Ion Beam Therapy
  • CT-based PET attenuation correction
  • Phantom development and testing
  • Treatment planning and outcome modeling
  • Adaptive image-guided radiotherapy end-to-end testing

Recent publications

Contact

Group picture (July 2020)

We are always looking for motivated students interested in applied medical physics to join our group. Please get in touch if you are interested! Our department also regularly offers projects within the DKFZ International PhD Program.

People:

Leticia Täubert (Research assistant)
Mohsin Raza (Master's student)
Yeong-Chul Yun (Master's student)
Dr. Clarissa Gillmann (Post-Doc)

Last updated: February 2021

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