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By sending your application documents and data you agree with the electronic processing of your personal data (title, first name, surname, date of birth, address, e-mail address, data from your application documents, listing of a severe disability) for the processing of your application by the COVIPA office and with the storage of your data for up to 6 months following the end of the application process. An application process is completed when the rejection letters are sent. If an application is revoked, the 6-months term starts with the confirmation of the revocation. Furthermore, you agree that your data will be transferred to the relevant divisions at DKFZ, FZJ, HZI, UFZ, Twincore, TUM and University Hospital Freiburg (e.g. staff of the Human Resources Department, authorized persons in the department advertising the position, the Staff Council, and in the case that applications of severely disabled persons have been submitted for the position, the Representative of Severely Disabled Persons) for processing your application. Responsible for all data from your application documents is the respective principal investigator.

 

Please send your applications to covipa-bw@dkfz-heidelberg.de 

Subproject 2 - Ralf Bartenschlager

OPEN POSITION for a postdoctoral fellow / doctoral student in the research group of Ralf Bartenschlager

The Bartenschlager group is studying the interaction between plus-strand RNA viruses and their host cells. One major focus is the 3D architecture, biogenesis and molecular composition of the membranous replication organelles of hepatitis C virus, flaviviruses (dengue virus, Zika virus) and SARS-CoV-2. We use standard molecular and cell biological methods, -omics based approaches (proteomics, lipidomics), genetic screening as well as cutting-edge light and electron microscopy methods (e.g. Cortese et al., 2020; Cerikan et al., 2020; Romero-Brey et al., 2012; Welsch et al., 2009). To complement our research team and to work on the SARS-CoV-2 replication organelle, we are seeking for a highly motivated postdoctoral fellow / PhD student. Desired qualifications are:

  • A Ph.D. / Master's (or equivalent degree) in biology or related field with an excellent publication record.
  • Strong hands-on experience with cryo-EM, conventional EM and light microscopy.
  • Solid experience in state-of-the-art cell and molecular biology techniques.
  • Profound knowledge in cell biology.
  • Sound knowledge in virology is of advantage.
  • The candidate works accurately, is able to conduct independent research, but also enjoys working in an international and interdisciplinary environment. The candidate is willing to advise students in the lab.
  • Good presentation skills and experience on project management (importance of scheduling, deliverables, reporting) will be highly valued.
  • Fluency in English language (written and spoken) is mandatory. Proficiency in German would be a plus.

Further information about our research can be found at:
https://www.klinikum.uni-heidelberg.de/Molecular-Virology.104862.0.html

References:

  • Cortese et al., 2020. Integrative imaging reveals SARS-CoV-2 induced reshaping of subcellular morphologies. Cell Host & Microbe 28(6):853-866.e5.
  • Cerikan et al., 2020. A Non-Replicative Role of the 3' Terminal Sequence of the Dengue Virus Genome in Membranous Replication Organelle Formation. Cell Reports 7;32(1):107859.
  • Romero-Brey et al., 2012. Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication. PLoS Pathog. 8(12):e1003056.
  • Welsch et al., 2009. Composition and three-dimensional architecture of the dengue virus replication and assembly sites. Cell Host Microbe 5:365-75.

Subproject 2

2 MD Students per year: Further information on request

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