Selected publications
- Rusu,P., Shao, C., Neuerburg, A., Acikgöz, A.A., Wu, Y., Zou, P., Phapale, P., Shankar, TS., Döring, K., Dettling, S., Körkel-Qu, H., Bekki, G., Costa, B., Guo, T., Friesen, O., Schlotter, M., Heikenwalder, M., Tschaharganeh, DF., Bukan, B., Kramer, G., Angel, P., Herold-Mende, C., Radlwimmer, B., Liu, H-K. (2019) GPD1 specifically marks dormant glioma stem cells with a distinct metabolic profile. Cell Stem Cell, DOI:https://doi.org/10.1016/j.stem.2019.06.004. Press release: English, German, Chinese.
- Costa, B., Eisemann, T., Strelau, J., Spaan, I., Korshunov, A., Liu, H.-K., Bugert, P., Angel, P., and Peterziel, H. (2019). Intratumoral platelet aggregate formation in a murine preclinical glioma model depends on podoplanin expression on tumor cells. Blood advances 3, 1092-1102.
- Duman, C., Yaqubi, K., Hoffmann, A., Acikgöz, A.A., Korshunov, A., Bendszus, M., Herold-Mende, C., Liu, H.-K., and Alfonso, J. (2019). Acyl-CoA-Binding Protein Drives Glioblastoma Tumorigenesis by Sustaining Fatty Acid Oxidation. Cell Metabolism.https://doi.org/10.1016/j.cmet.2019.04.004
- Feng, W., Herbst, L., Lichter, P., Pfister, S.M., Liu, H-K., and Kawauchi, D. (2018). CRISPR-mediated Loss of Function Analysis in Cerebellar Granule Cells Using In Utero Electroporation-based Gene Transfer. JoVE (Journal of Visualized Experiments), e57311.
- Lupo, G., Nisi, P.S., Esteve, P., Paul, Y.L., Novo, C.L., Sidders, B., Khan, M.A., Biagioni, S., Liu, H-K., and Bovolenta, P. (2018). Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age‐associated neurogenic decline. Aging Cell 17, e12745.
- Yong-Sheng Cheng , Yue Zhuo , Katharina Hartmann , Peng Zou , Gözde Bekki , Heike Alter, Hai-Kun Liu. (2017) Autonomous combinatorial color barcoding for multiplexing single molecule RNA visualization.
- Feng,W., Shao,C., Liu H-K. (2017) Versatile roles of the chromatin remodeler CHD7 during brain development and disease. Frontiers in Molecular Neuroscience. 10:309.doi: 10.3389/fnmol.2017.00309
- Liu H-K. (2017) Artemisinin, GABA signaling and cell reprogramming: when an old drug meets modern medicine. Science Bulletin. 62(6) 386-387
- Feng, W., Kawauchi, D., Koekel-Qu, H., Deng, H., Serger, E., Sieber, L., Lieberman, JA., Jimeno-Gonzalez, S., Lambo, S., Hanna, B., Harim, Y., Jansen, M., Neuerburg, A., Friesen, O., Zuckermann, M., Rajendran,V., Gronych, J., Ayrault, O., Korshunov, A., Jones, D., Kool, M., Northcott, P., Lichter, P., Cortes-Ledesma, F., Pfister, SM., Liu H-K. (2017) Chd7 is indispensable for mamalian brain development through activation of a neuronal differentiation program. Nature Communications.14758 (2017)
- Feng, W., Liu, H-K. (2017) Revealing the hidden powers that fuel adult neurogenesis. Cell Stem Cell. 20 (2), 154-156
- Wang Q, Satomi K, Oh JE, Hutter B, Brors B, Diessl N, Liu H-K, Wolf S, Wiestler O, Kleihues P, Koelsch B, Kindler-Rohrborn A, Ohgaki H (2016) Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Nitrosourea. American Journal of Pathology 186 (10), 2569-2576
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Osswald, M., Jung, E., Sahm, F., Solecki, G., Venkataramani, V., Blaes, J., Weil, S., Horstmann, H., Wiestler, B., Syed, M., Huang, L., Ratliff, M., Karimian Jazi, K., Kurz, F. T., Schmenger, T., Lemke, D., Gommel, M., Pauli, M., Liao, Y., Haring, P., Pusch, S., Herl, V., Steinhauser, C., Krunic, D., Jarahian, M., Miletic, H., Berghoff, A. S., Griesbeck, O., Kalamakis, G., Garaschuk, O., Preusser, M., Weiss, S., Liu, H-K., Heiland, S., Platten, M., Huber, P. E., Kuner, T., von Deimling, A., Wick, W. and Winkler, F. (2015) Brain tumour cells interconnect to a functional and resistant network. Nature, 528, 93–98
- Zhu, Z., Kahn, A., Weiler, M., Blaes. J, Jestaedt L., Geibert M., Zou P., Gronych J., Bernhardt, O., Korshunov, A., Bugner, V., Lichter, P., Radlwimmer, B., Heiland S., Bendszus, M., Wick, W., Liu, H-K*. (2014) Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival. Cell Stem Cell,15, 185-198 (* corresponding author. Highlighted in Nature Reviews Cancer: Cancer stem cell knockout! Previewed in Cell Stem Cell: The tailless root of glioma: cancer stem cells. Cell Stem Cell: Best of 2014, Total 8 Articles were selected)
- Feng, W., Kahn, A., Bellvis P., Zhu, Z., Bernhardt, O., Herold-Mende, C., Liu, H-K*. (2013). The chromatin remodeler CHD7 regulates adult neurogenesis via activation of SoxC transcription factors. Cell Stem Cell, 13, 62–72 (*corresponding author, Highlighted with a preview in Cell Stem Cell entitled CHD7 in charge of neurogenesis.)
- Feng, W., Liu, H-K. (2013). Epigenetic regulation of neuronal fate determination: The role of CHD7. Cell Cycle, 21, 12(24)
- Wang Y, Liu H-K, Schütz G. (2013). Role of the nuclear receptor tailless in adult neural stem cells. Mechanisms of development, 130(6-8):388-90
- Peterziel H, Müller J, Danner A, Barbus S, Liu H-K, Radlwimmer B, Pietsch T, Lichter P, Schütz G, Hess J, Angel P. (2012). Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation. Neuro Oncol. 14,426-39
- Liu H-K., Wang, Y., Belz, T., Bock, D., Takacs, A., Radlwimmer, B., Barbus, S., Reifenberger, G., Lichter, P., Schütz, G. (2010). The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation. Genes Dev 24:683-695 (Highlighted, Nature 08. April. 2010, Top of most read papers in Genes Dev, Highlighted by Faculty 1000 biology, F1000 Score 6.0 must read paper)
- Liu H-K., Belz T., Bock D., Takacs A., Wu H., Lichter P., Chai M-Q., Schütz G. (2008) The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone. Genes Dev 22:2473-2478 (Highlighted by Faculty 1000 biology, F1000 Score 6.0 must read paper)
- Belz, T., Liu, H-K., Bock, D., Takacs, A., Vogt, M., Wintermantel, T., Brandwein, C., Gass, P., Greiner, E., and Schütz, G. (2007). Inactivation of the gene for the nuclear receptor tailless in the brain preserving its function in the eye. Eur J Neurosci 26, 2222-2227.