Clinical Epidemiology of Early Cancer Detection
- Epidemiology, Public Health, Prevention and Survivorship
Dr. Sigrid Carlsson
Head of Division
The Clinical Epidemiology of Early Cancer Detection Division’s main areas of research include clinical cancer epidemiology, epidemiology of chronic age-related diseases and epidemiological methods.
Our Research
We conduct population-based research to improve cancer prevention, early detection and long-term outcomes. A central focus is the development and evaluation of risk-stratified screening strategies that tailor screening, diagnostic intensity and follow-up to individual risk profiles.
Colorectal and prostate cancer are major focus areas of the division. In colorectal cancer, we study screening strategies, participation, implementation and downstream outcomes to inform organized population-based programs. In prostate cancer, our research similarly spans the entire pathway from risk assessment and screening to diagnosis, treatment decisions and long-term outcomes, with particular emphasis on reducing overdiagnosis and overtreatment while maintaining favorable outcomes and quality-of-life.
The division also conducts early detection and outcomes research in breast cancer, lung cancer and other malignancies, and addresses multi-cancer early detection approaches. In parallel, we carry out epidemiological studies of chronic age-related diseases, reflecting the growing importance of multimorbidity and functional outcomes in aging populations.
Our research is anchored in large prospective population-based epidemiological studies with long-term follow-up, enriched with clinical data, questionnaires, and molecular and biomarker measurements including tumor heterogeneity research. We work in close collaboration with clinical partners, basic scientists and cancer registries, enabling translational research across the full continuum from risk assessment to population-level implementation.
We conduct observational studies, randomized controlled trials, using advanced epidemiological and biostatistical methods to deliver research with direct implications for health policy and guideline development and implementation.