Translational Research

Translational research (clinical research)

The German Cancer Research Center (DKFZ) is one of the most important cancer research institutions in the world and is particularly well positioned in the field of basic research and early translation research. In order to ensure that research results and developments can be put into practice more quickly in a clinical setting for future patient care, we draw on a wide range of know-how as well as highly specialized, networked infrastructures, rounded out by the very close cooperation between researchers and clinical physicians.
With our translation locations in Germany and the ability to use them in connection with the DKFZ, we are working to optimize processes and make the results more applicable for patients. Each location is jointly supported by the DKFZ through partners at the respective university hospitals.

National Center for Tumor Diseases (NCT)

© NCT Heidelberg / Philip Benjamin

The National Center for Tumor Diseases (NCT) is committed to the task of linking research and patient care as closely as possible. In addition to Heidelberg, an NCT partner site will be established in Dresden.

Cancer patients at the NCT are treated based on the latest scientific findings. At the same time, scientists benefit in their practical research from the proximity between the laboratories and clinics. The NCT strives to provide each patient with individualized therapies according to their specific needs – beyond the boundaries of traditional disciplines and academic departments, according to modern precision oncology. A common goal of both sites is to develop the NCT into an international center of excellence in cancer research. The NCT locations in Heidelberg and Dresden are the leading oncology centers of German Cancer Aid.

German Cancer Consortium (DKTK)

© DKTK

Promising, new results from cancer research should be incorporated as quickly as possible into clinical development and application. To support this goal, the German Cancer Consortium (DKTK) was founded in 2012 as one of the six German Centers of Health Research (DZG). Over 20 academic research institutes and university hospitals at seven partner locations cooperate with the German Cancer Research Center (DKFZ) as the core center.

Hopp Children’s Cancer Center Heidelberg (KiTZ)

© Flugkraft

The Hopp Children's Cancer Center Heidelberg (KiTZ) is a joint institution of the German Cancer Research Center (DKFZ), Heidelberg University Hospital (UKHD), and Heidelberg University (Uni HD). It is also a therapy and research center for oncological and hematological diseases in children and adolescents. The center's aim is to conduct scientific research on the biology of childhood cancer and severe blood diseases and closely connect promising research approaches to patient care.

Helmholtz Institute for Translational Oncology (HI-TRON Mainz)

© Jürgen Arlt / DKFZ

The Helmholtz Institute for Translational Oncology (HI-TRON Mainz) is the result of the close cooperation between the German Cancer Research Center (DKFZ) and the Research Institute for Translational Oncology (TRON gGmbH) at the University Medical Center of the Johannes Gutenberg University Mainz. The mission of HI-TRON Mainz is to make full use of the potential of individualized immunotherapy for the benefit of people with cancer, based on the know-how and success results of the partners. The strategic goal is to position Germany among the world’s leaders in this innovative and relevant field. The research projects are selected based on the strict requirement of ensuring the immediate value for the patient as a top priority.

DKFZ-Hector Cancer Institute at the University of Mannheim

Cancer is the second most frequent disease-related cause of death and is one of the most strongly feared diseases in Germany. In addition to better prevention and new diagnostic methods, a systematic development of patient-oriented research into personalized precision oncology is required to address cancer in a targeted and successful way. Comprehensive cancer centers (CCC) around the world, which bring together outstanding research with excellent multidisciplinary oncological care, are driving forward patient-oriented cancer research. To establish the "DKFZ-Hector Cancer Institute at the University Medical Center Mannheim" DKFZ, University Medical Center Mannheim and Medical Faculty Mannheim at the University Heidelberg have entered a partnership to perform patient-oriented translational cancer research on an internationally competitive level. This long-term partnership will be funded by the Hector Foundation II for the next ten years, with generous support of € 2.5 million a year.

Clinical Trial Office

The DKFZ Clinical Trial Office (CTO) was founded in April 2018 to generate a strategic portfolio of clinical trials and data by enabling the performance of high-quality clinical trials under formal sponsorship of DKFZ. The CTO's main tasks are the establishment and implementation of structures and processes to ensure DKFZ's sponsor oversight in the start-up and conduction phase of clinical drug trials. In addition, the CTO is responsible for the scientific and administrative framework needed to support clinical research at DKFZ.

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