The p53 stem cell paradigm

Varda Rotter - Weizmann Institute of Science

17:00 DKFZ Main Auditorium

Host: O. Wiestler

Biosketch Varda Rotter

Prof. Varda Rotter is the Director of the Women’s Health Center and a memberof the Department of Molecular Cell Biology at the Weizmann Institute of Science in Rehovot, Israel. She was among the pioneers in discovering the p53 protein and providing new insights into its molecular and cell biology. One of her most significant contributions to the p53 field was her pioneering work in establishing the mutant p53 gain of function paradigm in carcinogenesis. She was the first to demonstrate that introduction of p53 (what is known today as mutant p53) into p53-null cells significantly facilitated their oncogenic activity in vivo and in vitro.

Varda Rotter is actively involved in many national and international committees dealing with science policy and promotion of scientific excellence, including the DKFZ Scientific Advisory Board. Her international recognition is also reflected in many invitations to deliver lectures and to write review articles for top journals such as Nature.

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