The p53 stem cell paradigm
Varda Rotter - Weizmann Institute of Science
17:00 DKFZ Main Auditorium
Host: O. Wiestler
Biosketch Varda Rotter
Prof. Varda Rotter is the Director of the Women’s Health
Center and a memberof the Department of Molecular Cell Biology at the Weizmann
Institute of Science in Rehovot, Israel. She was among the pioneers in
discovering the p53 protein and providing new insights into its molecular and
cell biology. One of her most significant contributions to the p53 field was her
pioneering work in establishing the mutant p53 gain of function paradigm in
carcinogenesis. She was the first to demonstrate that introduction of p53 (what
is known today as mutant p53) into p53-null cells significantly facilitated
their oncogenic activity in vivo and in vitro.
Varda Rotter is actively involved in many national and international committees dealing with science policy and promotion of scientific excellence, including the DKFZ Scientific Advisory Board. Her international recognition is also reflected in many invitations to deliver lectures and to write review articles for top journals such as Nature.