Research
- Research Topics
- Cell Biology and Tumor Biology
- Stem Cells and Cancer
- Inflammatory Stress in Stem Cells
- Experimental Hematology
- Molecular Embryology
- Signal Transduction and Growth Control
- Epigenetics
- Redox Regulation
- Vascular Oncology and Metastasis
- Clinical Neurobiology
- Molecular Neurogenetics
- Molecular Neurobiology
- Mechanisms Regulating Gene Expression
- Molecular Biology of Centrosomes and Cilia
- Dermato-Oncology
- Pediatric Leukemia
- Tumour Metabolism and Microenvironment
- Personalized Medical Oncology
- Molecular Hematology - Oncology
- Cancer Progression and Metastasis
- Translational Surgical Oncology
- Neuronal Signaling and Morphogenesis
- Cell Signaling and Metabolism
- Cell Fate Engineering and Disease Modeling
- Cancer Drug Development
- Cell Morphogenesis and Signal Transduction
- Functional and Structural Genomics
- Molecular Genome Analysis
- Molecular Genetics
- Pediatric Neurooncology
- Cancer Genome Research
- Chromatin Networks
- Functional Genome Analysis
- Theoretical Systems Biology
- Neuroblastoma Genomics
- Signaling and Functional Genomics
- Signal Transduction in Cancer and Metabolism
- RNA-Protein Complexes and Cell Proliferation
- Systems Biology of Signal Transduction
- Areas of Interest
- Advancement of clinical proteomics for systems medicine
- Bridging from the single cell to the cell population – Epo-induced cellular responses and erythroleukemia
- Deciphering tumor microenvironment interactions determining lung cancer development
- Mechanisms controlling the compensation of liver injury and towards model-based biomarkers for early detection of liver cancer
- Application of dynamic pathway modelling for personalized medicine
- Group Members
- Publications
- Open Positions
- Funding
- Teaching
- Areas of Interest
- Molecular thoracic Oncology
- Proteomics of Stem Cells and Cancer
- Computational Genomics and System Genetics
- Applied Functional Genomics
- Applied Bioinformatics
- Translational Medical Oncology
- Metabolic crosstalk in cancer
- Pediatric Glioma Research
- Cancer Epigenomics
- Translational Pediatric Sarcoma Research
- Artificial Intelligence in Oncology
- Mechanisms of Genomic Variation and Data Science
- Neuropathology
- Pediatric Oncology
- Neurooncology
- Somatic Evolution and Early Detection
- Translational Control and Metabolism
- Soft-Tissue Sarcoma
- Precision Sarcoma Research
- Brain Mosaicism and Tumorigenesis
- Mechanisms of Genome Control
- Translational Gastrointestinal Oncology and Preclinical Models
- Translational Lymphoma Research
- Mechanisms of Leukemogenesis
- Genome Instability in Tumors
- Developmental Origins of Pediatric Cancer
- Brain Tumor Translational Targets
- Translational Functional Cancer Genomics
- Regulatory Genomics and Cancer Evolution
- SPRINT
- Cancer Risk Factors and Prevention
- Cancer Epidemiology
- Biostatistics
- Clinical Epidemiology and Aging Research
- Health Economics
- Physical Activity, Prevention and Cancer
- Preventive Oncology
- Personalized Early Detection of Prostate Cancer
- Digital Biomarkers for Oncology
- Tumorigenesis and molecular cancer prevention
- Genomic Epidemiology
- Cancer Survivorship
- Immunology, Infection and Cancer
- Structural Biology of Infection and Immunity
- Cellular Immunology
- B Cell Immunology
- Immune Diversity
- Immunoproteomics
- Personalized Immunotherapy
- mRNA Cancer Immunotherapies
- Tumor Immunology and Tumor Immunotherapy
- Infections and Cancer Epidemiology
- Pathogenesis of Virus-Associated Tumors
- Immunotherapy and Immunoprevention
- Virus-associated Carcinogenesis
- Chronic Inflammation and Cancer
- Microbiome and Cancer
- Molecular Oncology of Gastrointestinal Tumors
- Applied Tumor Immunity
- Neuroimmunology and Brain Tumor Immunology
- Applied Tumor Biology
- Virotherapy
- Adaptive Immunity and Lymphoma
- Dermal Oncoimmunology
- Immune Regulation in Cancer
- Systems Immunology and Single Cell Biology
- Pediatric Immuno-Oncology
- Experimental Hepatology, Inflammation and Cancer
- GMP & T Cell Therapy
- Tumorvirus-specific Vaccination Strategies
- Mammalian Cell Cycle Control Mechanisms
- Molecular Therapy of Virus-Associated Cancers
- DNA Vectors
- Episomal-Persistent DNA in Cancer- and Chronic Diseases
- Immune Monitoring
- News
- Imaging and Radiooncology
- Radiology
- Research
- Computational Radiology Research Group
- Contrast Agents In Radiology Research Group
- Neuro-Oncologic Imaging Research Group
- Radiological Early Response Assessment Of Modern Cancer Therapies
- Imaging In Monoclonal Plasma Cell Disorders
- 7 Tesla MRI - Novel Imaging Biomarkers
- Functional Imaging
- Visualization And Forensic Imaging
- PET/MRI
- Dual- and Multienergy CT
- Radiomics Research Group
- Prostate Research Group
- Bone marrow
- Musculoskeletal Imaging
- Microstructural Imaging Research Group
- Staff
- Patients
- Research
- Medical Physics in Radiology
- X-Ray Imaging and Computed Tomography
- Federated Information Systems
- Translational Molecular Imaging
- Medical Physics in Radiation Oncology
- Biomedical Physics in Radiation Oncology
- Intelligent Medical Systems
- Medical Image Computing
- Radiooncology - Radiobiology
- Smart Technologies for Tumor Therapy
- Radiation Oncology
- Molecular Radiooncology
- Nuclear Medicine
- Translational Radiation Oncology
- Translational Radiotheranostics
- Interactive Machine Learning
- Intelligent Systems and Robotics in Urology
- Multiparametric methods for early detection of prostate cancer
- Translational Molecular Imaging in Oncologic Therapy Monitoring
- Radiology
- Cell Biology and Tumor Biology
- Research Groups A-Z
- Junior Research Groups
- Core Facilities
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- List of Core Facilities
- Antibodies
- Cellular Tools
- Center for Preclinical Research
- Central Library
- Chemical Biology
- Dieter Morszeck Biorepository
- Electron Microscopy
- Flow Cytometry
- Information Technology ITCF
- Light Microscopy
- Metabolomics
- Microarray
- Microbiological Diagnostics
- Next Generation Sequencing
- Omics IT and Data Management
- Proteomics
- Radiopharmaceuticals and Preclinical Trials
- Single-cell Open Lab
- Small Animal Imaging
- Transgenic Service
- Tumor Models
- OMERO@DKFZ
- List of Technologies
- DKFZ Core Facilities Publication Policy
- Core Facilities Head Office - Enabling Technology Department
- Data Science @ DKFZ
- INFORM
- Baden-Württemberg Cancer Registry
- Cooperations & Networks
- National Cooperations
- International Cooperations
- Cooperational Research Program with Israel: DKFZ - MOST in Cancer Research
- Program
- Members of the Program Committee
- Call
- Publication Database
- German-Israeli Cancer Research Schools
- Archive
- Heidelberg - Israel, Science and Culture
- Symposium 40 Years of German-Israeli Cooperation
- 35th Anniversary Symposium
- 34th Meeting of the DKFZ-MOST Program
- 40th Anniversary Publication
- 30th Anniversary Publication
- 20th Anniversary Publication
- Flyer - The Cancer Cooperation Program
- List Publications 1976-2004
- Highlight-Projects
- Cooperational Research Program with Israel: DKFZ - MOST in Cancer Research
- Cooperations with industrial companies
- DKFZ PostDoc Network
- Cross Program Topic RNA@DKFZ
- Cross Program Topic Epigenetics@dkfz
- Cross Program Topic Single Cell Sequencing
- WHO Collaborating Centers
- DKFZ Site Dresden
- Health + Life Science Alliance Heidelberg Mannheim
Publications
Publications listed below are related to the current projects and recent research activities. A complete publication list can be found under the ORCID number https://orcid.org/0000-0002-7030-8153 from Maïwen Caudron-Herger
Selected Original Research Articles
Wassmer E, Koppány G, Hermes M, Diederichs S and Caudron-Herger M. Refining the pool of RNA-binding domains advances the classification and prediction of RNA-binding proteins.
Nucleic Acids Res. 2024; gkae536, https://doi.org/10.1093/nar/gkae536
Rajagopal V, Loubal AS, Engel N, Wassmer E, Seiler J, Schilling O, Caudron-Herger M and Diederichs S. Proteome-wide identification of RNA-dependent proteins in lung cancer cells.
Cancers. 2022; 14:6109.
Caudron-Herger M*, Ralf E. Jansen, Elsa Wassmer and Sven Diederichs. RBP2GO: a comprehensive pan-species database on RNA-binding proteins, their interactions and functions.
Nucleic Acids Res. 2021; 49:D425-436. *Corresponding author.
Lyu Y, Caudron-Herger M and Diederichs S. circ2GO: a database linking circular RNAs to gene function.
Cancers. 2020; 12:2975.
Dhamija S, Yang CM, Seiler J, Myacheva K, Caudron-Herger M, Wieland A, Adbelkarim M, Sharma Y, Riester M, Gross M, Maurer J and Diederichs S. A pan-cancer analysis reveals non-stop extension mutations causing SMAD4 tumour suppressor degradation.
Nature Cell Biology. 2020; 22:999-1010.
Caudron-Herger M*, Barreau E, Nasa I, Schultz A, Seiler J, Kettenbach AN and Diederichs S*. Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP.
Nature Protocols. 2020; 15:1338-1370. *Corresponding authors.
Caudron-Herger M*, Rusin SF, Adamo ME, Seiler J, Schmid V, Barreau E, Kettenbach AN and Diederichs S*. R-DeeP: Proteome-wide and quantitative identification of RNA-dependent proteins by density gradient ultracentrifugation.
Mol Cell. 2019; 75:184-199. *Corresponding authors.
Sharma Y, Miladi M, Dukare S, Boulay Karine, Caudron-Herger M, Groß Matthias, Backhofen Rolf and Diederichs S. A pan-cancer analysis of synonymous mutations.
Nat. Commun. 2019; 10, Article number:2569.
Goyal A, Fiskin E, Gutschner T, Polycarpou-Schwarz M, Groß M, Neugebauer J, Gandhi M, Caudron-Herger M, Benes V and Diederichs S. A cautionary tale of sense-antisense gene pairs: Independent regulation despite inverse correlation of expression.
Nucleic Acids Research. 2017; 45: 12496-12508.
Seiler J, Breinig M, Caudron-Herger M, Polycarpou-Schwarz M, Boutros M, and Diederichs S. The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance.
Nucleic Acids Res. 2017; epub: DOI: 10.1093/nar/gkx076.
Selected Reviews and Comments
Caudron-Herger M and Diederichs S. Insights from the degradation mechanism of Cyclin D into targeted therapy of the cancer cell cycle.
Sig Transduct Target Ther. 2021; 6: 311. DOI: https://doi.org/10.1038%2Fs41392-021-00732-y
Gandhi M., Caudron-Herger M and Diederichs S. RNA motif and combinatorial prediction of interactions, stability and localization of noncoding RNAs.
Nat Struct Mol Biol. 2018; 24: 1070-1076. DOI: 10.1038/s41594-018-0155-0.