Cookie Settings

We use cookies to optimize our website. These include cookies that are necessary for the operation of the site, as well as those that are only used for anonymous statistic. You can decide for yourself which categories you want to allow. Further information can be found in our data privacy protection .


These cookies are necessary to run the core functionalities of this website and cannot be disabled.

Name Webedition CMS
Purpose This cookie is required by the CMS (Content Management System) Webedition for the system to function correctly. Typically, this cookie is deleted when the browser is closed.
Name econda
Purpose Session cookie emos_jcsid for the web analysis software econda. This runs in the “anonymized measurement” mode. There is no personal reference. As soon as the user leaves the site, tracking is ended and all data in the browser are automatically deleted.

These cookies help us understand how visitors interact with our website by collecting and analyzing information anonymously. Depending on the tool, one or more cookies are set by the provider.

Name econda
Purpose Statistics
External media

Content from external media platforms is blocked by default. If cookies from external media are accepted, access to this content no longer requires manual consent.

Name YouTube
Purpose Show YouTube content
Name Twitter
Purpose activate Twitter Feeds

LEO Study

LEO is a German acronym and stands for "Leben ohne Darmkrebs" (Life Without Colon Cancer).

The LEO Study is a large-scale scientific study conducted by the Preventive Oncology Division at the National Center for Tumor Diseases (NCT) Heidelberg together with the Interdisciplinary Endoscopy Centre Heidelberg.
Since 2020 the LEO study team has been recruiting participants from the age group 30-49 based on the NCT "Proof of Concept Trial".

Medizinische Klinik Krehl Klinik

The main objective of the study is to discover and evaluate new screening tests by means of which colon cancer and its pre-stages can be detected earlier.

The LEO study is part of the Prevention Outpatient Clinic that started its work on January 31, 2023. This clinic is the heart of the National Cancer Prevention Center (NCPC) which is currently being set up in Heidelberg by the DKFZ and the German Cancer Aid.

The Preventive Oncology Division also focusses on risk-adapted prevention (RAD). The RAD team led by Dr. Mahdi Fallah focusses on targeted prevention in the high-risk group of first-degree relatives of cancer patients.

The Objective of the Study

The main objective of the study is to discover and evaluate new screening tests by means of which colon cancer and its pre-stages can be detected earlier. The main focus is on young adults from the age group 30-49.
Further goals are to explore the prevalence of colon cancer and methods to identify high-risk groups with pre-stages of the disease. Based on our findings, we will derive recommendations for a personalized age for colon cancer screening.

Another focus of research is the question how well screening of the colon for polyps and other noticeable changes is accepted in the 30 to 49 age group and which results can be derived from this.

The participants of the LEO study do not undertake to undergo a medical examination. Their participation can be limited to part I of the study which consists of filling in our online questionnaires (questions about their diet and status of health). They can also provide bio samples that help us to develop simple early detection tests.

However, our offer to get a free of charge colonoscopy is attractive for this age group since the German healthcare system usually does not cover for this examination before age 50. Early detection of cancer significantly improves the chances of recovery. Colon cancer can even be avoided by preventive check-ups.

to top
powered by webEdition CMS