Cookie Settings

We use cookies to optimize our website. These include cookies that are necessary for the operation of the site, as well as those that are only used for anonymous statistic. You can decide for yourself which categories you want to allow. Further information can be found in our data privacy protection .


These cookies are necessary to run the core functionalities of this website and cannot be disabled.

Name Webedition CMS
Purpose This cookie is required by the CMS (Content Management System) Webedition for the system to function correctly. Typically, this cookie is deleted when the browser is closed.
Name econda
Purpose Session cookie emos_jcsid for the web analysis software econda. This runs in the “anonymized measurement” mode. There is no personal reference. As soon as the user leaves the site, tracking is ended and all data in the browser are automatically deleted.

These cookies help us understand how visitors interact with our website by collecting and analyzing information anonymously. Depending on the tool, one or more cookies are set by the provider.

Name econda
Purpose Statistics
External media

Content from external media platforms is blocked by default. If cookies from external media are accepted, access to this content no longer requires manual consent.

Name YouTube
Purpose Show YouTube content
Name Twitter
Purpose activate Twitter Feeds

Tumor-host interaction in the tumor microenvironment and the periphery

The comprehensive analysis of tumor-host cell interactions, especially focusing on immune cells and the spatial analysis of the tumor microenvironment by immunohistochemistry (IHC), multiplex analyses, virtual microscopy and semi-automated image analysis is another main objective of the division. The molecular mechanisms underlying the clinical impact and the causes of the observed differences in the immunological tumor micro-milieu are not yet fully understood. Therefore, the dedicated analysis of the tumor compartments (stroma, epithelium, invasion front, and surrounding tissue) with respect to localization of immune cells and cytokine profiling in the light of the clinical course will yield a better image of the complex relations and eventually support the development of new drugs and targeted treatment approaches for patients. Together with the NCT TME Unit and the NCT Unit for „Applied Tumor Therapy and Combinational Strategies", the division supports collaboration projects and clinical studies, such as PROMISE, NEOMUN, CATCH, COGNITION and MASTER. The D120 is closely interacting with other units of the NCT Immunotherapy Program, which has been established to support drug- and target-development for novel immunotherapies (e.g. antibody-based strategies, cellular approaches and vaccines). This includes pre-clinical testing in cell culture, in human tissue model systems as well as small animal models. Therapeutic approaches tested include (although not limited to) immunomodulatory substances, CAR-T cells, TCR-T cells, tumor-infiltrating lymphocytes and combinations thereof.


Inka Zörnig, PhD - 

Bénédicte Lenoir, PhD - 

to top
powered by webEdition CMS