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Immune Monitoring Unit

Prof. Dr. Michael Platten

Analysis of active and tumor-specific T cells via ELISpot assay.
© dkfz.de

The Immune Monitoring Unit accompanies oncological trials (IITs or industry-sponsored trials) of all phases using various immunological analysis techniques. We accompany you from the idea of a study to the final report or publication. With the help of state-of-the-art analyzes and proven analyzes, we can study the sample material as best as possible. Our employees are constantly upskilled to incorporate the latest research findings into analyzes. Standardized work according to SOPs makes our evaluations comparable. Please don’t hesitate to contact us.

Contact

Prof. Dr. Michael Platten
Immune Monitoring Unit (G808)
Deutsches Krebsforschungszentrum
und Nationales Centrum für Tumorerkrankungen (NCT)
Im Neuenheimer Feld 460
69120 Heidelberg

Contact:
Dr. Isabel Poschke
Tel: +49 6221-56-35210
E-Mail: i.poschke@dkfz.de

Selected Publications

  • Poschke IC, Hassel JC, Rodriguez-Ehrenfried A, Lindner KAM, Heras-Murillo I, Appel LM, Lehmann J, Lövgren T, Wickström SL, Lauenstein C, Roth J, König AK, Haanen JBAG, van den Berg J, Kiessling R, Bergmann F, Flossdorf M, Strobel O, Offringa R. The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones. Clin Cancer Res. 2020 Aug 15;26(16):4289-4301. Epub 2020 Apr 17. PMID: 32303540
  • Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, Sahm F, Sanghvi K, Tan CL, Poschke I, Green E, Justesen S, Behrens GA, Breckwoldt MO, Freitag A, Rother LM, Schmitt A, Schnell O, Hense J, Misch M, Krex D, Stevanovic S, Tabatabai G, Steinbach JP, Bendszus M, von Deimling A, Schmitt M, Wick W. A vaccine targeting mutant IDH1 in newly diagnosed glioma. Nature. 2021 Apr;592(7854):463-468.
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