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NGS Core Facility

The NGS Core Facility provides highly parallel DNA sequencing services based on the Illumina MiSeq, NextSeq and NovaSeq technologies as well as on the Oxford Nanopore technologies.



  • DNA Sequencing

    • Whole Genome Sequencing
    • Targeted Resequencing (e.g. Exome Sequencing)
    • De-Novo Sequencing
  • RNA-Sequencing

    • mRNA stranded
    • UltraLowRNA
    • RiboZero
  • Bisulfite Sequencing

    • Analysis of DNA methylation patterns via Whole Genome


Our services

  • Assistance in experimental design
  • Sample preparation starting from customer prepared DNA/RNA
  • Sequencing service for customer libraries and multiplexes
  • Sequence analysis on Illumina:
    • MiSeq (50, 300 and 500 cycles kit on V2 flowcell; 150 and 600 cycles kit on V3 flowcell)
    • NextSeq 550 (75, 150 and 300 cycles kit on MidOutput flowcell; 150 and 300 cycles kit on HighOutput flowcell)
    • NovaSeq 6000 (100, 200, 300 and 500 cycles kit on SP flowcell; 100, 200 and 300 cycles kit on S1 and S2 flowcell; 35, 200 and 300 cycles kit on S4 flowcell)
    • NovaSeq X Plus (100, 200 and 300 cycles kit on 10B flowcell)
  • Provision of the full sequence data
  • Basic bioinformatics support for the analysis of resulting sequence data
  • Sequencing Open Lab
    • Illumina technologies:
      • NextSeq 550
      • NextSeq 2000
    • Oxford Nanopore technologies:
      • GridION
      • PromethION


For detailed information about the our service, different platforms as well as pooling recommendation please check our FAQs in ILSe or contact Dr. Stephan Wolf or Dr. Angela Schulz.


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