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Home
Research
Research Topics
Functional and Structural Genomics
Regulatory Genomics and Cancer Evolution
Publications

Research

Publications (2018-2024)

 

  • The dynamic genetic determinants of increased transcriptional divergence in spermatids
    J Panten, T Heinen, C Ernst, N Eling, RE Wagner, M Satorius, JC Marioni, Nature Communications 2024

  • The cycling and aging mouse female reproductive tract at single-cell resolution
    I Winkler, A Tolkachov, F Lammers, P Lacour, K Daugelaite, N Schneider, ...Cell 2024

  • Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice
    MC Funk, JG Gleixner, F Heigwer, D Vonficht, E Valentini, Z Aydin, ...Developmental Cell 2023

  • Four-Core Genotypes mice harbour a 3.2 MB XY translocation that perturbs Tlr7 dosage
    J Panten, SD Prete, JP Cleland, LM Saunders, J van Riet, A Schneider, ...BioRxiv 2023

  • An interactive cellular ecosystem blocks epithelial transformation in naked mole-rat
    M Behm, P Baeza Centurión, L Penso-Dolfin, FJ Botey Bataller, ...BioRxiv 2023

  • A transcriptional and regulatory map of mouse somite maturation
    X Ibarra-Soria, E Thierion, GF Mok, AE Münsterberg, DT Odom, ...Developmental Cell 2023

  • Superovulation and aging perturb oocyte-granulosa cell communication
    K Daugelaite, P Lacour, I Winkler, ML Koch, A Schneider, N Schneider, ...BioRxiv 2023

  • Strand-resolved mutagenicity of DNA damage and repair
    CJ Anderson, L Talmane, J Luft, MD Nicholson, J Connelly, O Pich, ...Biorxiv 2022

  • LINE retrotransposons characterize mammalian tissue-specific and evolutionarily dynamic regulatory regions
    M Roller, E Stamper, D Villar, O Izuogu, F Martin, AM Redmond, ...Genome Biology 2021

  • Functional signatures of evolutionarily young CTCF binding sites
    D Azazi, JM Mudge, DT Odom, P Flicek BMC Biology 2020

  • Clustered CTCF binding is an evolutionary mechanism to maintain topologically associating domains
    E Kentepozidou, SJ Aitken, C Feig, K Stefflova, X Ibarra-Soria, DT Odom, ...Genome Biology 2020

  • Pervasive lesion segregation shapes cancer genome evolution
    SJ Aitken, CJ Anderson, F Connor, O Pich, V Sundaram, C Feig, ...Nature 2020

  • A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division
    L Stojic, ATL Lun, P Mascalchi, C Ernst, AM Redmond, J Mangei, AR Barr, ...Nature Communications 2020

  • Bookmarking by non-pioneer transcription factors during liver development establishes competence for future gene activation
    P Karagianni, P Moulos, D Schmidt, DT Odom, I Talianidis  Cell Reports 2020

  • Crisflash: open-source software to generate CRISPR guide RNAs against genomes annotated with individual variation
    ALS Jacquin, DT Odom, M Lukk  Bioinformatics 2019

  • IL‐7‐dependent compositional changes within the γδ T cell pool in lymph nodes during ageing lead to an unbalanced anti‐tumour response
    HC Chen, N Eling, CP Martinez‐Jimenez, LMN O'Brien, V Carbonaro, ... EMBO Reports 2019

  • Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia
    M Yang, M Vesterlund, I Siavelis, LH Moura-Castro, A Castor, T Fioretos, ...Nature Communications 2019

  • Staged developmental mapping and X chromosome transcriptional dynamics during mouse spermatogenesis
    C Ernst, N Eling, CP Martinez-Jimenez, JC Marioni, DT Odom  Nature Communications 2019

  • CTCF maintains regulatory homeostasis of cancer pathways
    SJ Aitken, X Ibarra-Soria, E Kentepozidou, P Flicek, C Feig, JC Marioni, ...Genome Biology 2018

  • Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species
    R Lowe, C Barton, CA Jenkins, C Ernst, O Forman, DS Fernandez-Twinn, ...Genome Biology 2018

  • Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci
    J Lilue, AG Doran, IT Fiddes, M Abrudan, J Armstrong, R Bennett, ...Nature Genetics 2018

  • Chromosome assembly of large and complex genomes using multiple references
    M Kolmogorov, J Armstrong, BJ Raney, I Streeter, M Dunn, F Yang, ...Genome Research 2018

  • Integrative detection and analysis of structural variation in cancer genomes
    JR Dixon, J Xu, V Dileep, Y Zhan, F Song, VT Le, GG Yardımcı, ...Nature Genetics 2018

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