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- Cell Biology and Tumor Biology
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- Signal Transduction in Cancer and Metabolism
- RNA-Protein Complexes and Cell Proliferation
- Systems Biology of Signal Transduction
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- Advancement of clinical proteomics for systems medicine
- Bridging from the single cell to the cell population – Epo-induced cellular responses and erythroleukemia
- Deciphering tumor microenvironment interactions determining lung cancer development
- Mechanisms controlling the compensation of liver injury and towards model-based biomarkers for early detection of liver cancer
- Application of dynamic pathway modelling for personalized medicine
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Modulation of redox biochemistry as an approach to cancer chemoprevention
ANNOUNCEMENT FOR OPEN PH.D. POSITION
In the frame of the EU-funded Marie Curie Training Network 'Red Cat' ("Natural Products and related Redox Catalysts: Basic Research and Applications in Medicine and Agriculture"), the DKFZ offers a Ph.D. position which will be supervised by Dr. Clarissa Gerhäuser (C010 Epigenomics and Cancer Risk Factors) and PD Dr. Tobias Dick (A160 Redox Regulation). The position is open in fall 2009. Please note that the concept of the training network involves exchange of researchers between institutions. Based on EU-regulations, we will hire a non-german student, who is currently not working in Germany.
The ‚Red Cat’ Training Network comprises ten partners from universities, research institutes and companies from five European countries. It addresses current and emerging issues in Medicine and Agriculture, such as the need for disease-preventive antioxidants for an ageing population, antibiotics against drug-resistant bacteria and ‘green’ pesticides for a healthy and ecologically acceptable agriculture of the future.
The research of the network is based on the premise that a combination of natural products and redox control of cellular events can be used to resolve many of these issues. The project is divided in four work packages that combine elements of basic and applied research. They all incorporate multidisciplinary expertise and methods, from the extraction/design of agents and synthetic chemistry to biochemistry, cell culture and in vivo tests against pests. Together, the WP provide scientific challenges for four experienced and ten early stage researchers in natural products, antioxidants, intracellular redox processes, green pesticides, pharmacology and innovative ways of selectively killing cancer cells by using redox catalysts.