Original- und Übersichtsarbeiten im Jahr 2015 und im Druck

Lin W-Y, Camp NJ, Ghoussaini M, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Dunning A, Easton DF, Cox A.
Identification and characterisation of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.
Human Molecular Genetics 2015; 24:285-298.

Campa D, Martino A, Varkonyi J, Lesueur F, Jamrozial K, Landi S, Jurczyszyn  A, Marques H, Andersen V, Jurado M, Brenner H, Petrini M, Vogel U, Garcia-Sanz R, Buda G, Gemignani F, Rios R, Vangsted AJ, Dumontet C, Martinez-Lopez J, Moreno MJ, Stepien A, Watek M, Moreno V, Dieffenbach AK, Rossi AM, Butterbach K, Jacobsen SEH, Goldschmidt H, Sainz J, Hillengass J, Orciuolo E, Dudzinski M, Weinhold N, Reis RM, Canzian F.
Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length.
International Journal of Cancer 2015; 136:E351-E358.

Conway DI, Brenner DR, McMahon AD, Macpherson LMD, Agudo A, Ahrens W, Bosetti C, Brenner H, ..., Müller H, ..., Lee YCA, Hashibe M, Brennan P.
Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case-control studies from 27 countries.
International Journal of Cancer 2015; 136:1125-1139.

Elgizouli M, Logan C, Nieters A, Brenner H, Rothenbacher D.
Cord blood PRF1 methylation patterns and risk of lower respiratory tract infections in infants: findings from the Ulm Birth Cohort.
Medicine 2015; 94:e332.

Glubb DM, Maranian MJ, Michailidou K, Pooley KA, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, .., Dunning AM, French JD.
Fine scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.
American Journal of Human Genetics 2015; 96:5-20.

Carvajal-Carmona L, O'Mara TA, Painter JN, ..., Brenner H, Dieffenbach AK, ..., Easton DF, Spurdle AB, Thompson DJ.
Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk.
Human Genetics 2015; 134:231-245.

Rudolph A, Milne RL, Truong T, ..., Dieffenbach AK, Arndt V, Stegmaier C, ..., Brenner H, ..., Pharoah PDP, Garcia-Closas M, Chang-Claude J.
Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors.
International Journal of Cancer 2015; 136:E685-E696.

GBD 2013 Mortality and Causes of Death Collaborators*.
Global, regional and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.
Lancet 2015; 385:117-171.
*Collaborators from DKFZ: Brenner H, Schöttker B.

Brenner H, Hoffmeister M, Birkner B, Stock C.
Which adenomas are detected by fecal occult blood testing? A state-wide analysis from Bavaria, Germany.
International Journal of Cancer 2015; 136:1672-1679.

Ashwin N, Ananthakrishnan AN, Du M, Berndt SI, Brenner H, Caan BJ, Casey G, Chang-Claude J, Duggan D, Fuchs CS, Gallinger S, Giovannucci EL, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hou L, Hsu L, Jenkins MA, Kraft P, Ma J, Nan H, Newcomb PA, Ogino S, Potter JD, Seminara D, Slattery ML, Thornquist M, White E, Wu K, Peters U, Chan AT.
Red meat intake, NAT2, and risk of colorectal cancer: A pooled analysis of 11 studies.
Cancer Epidemiology, Biomarkers and Prevention 2015; 24:198-205.

Dallmeier D, Pencina MJ, Rajman I, Koenig W, Rothenbacher D, Brenner H.
Serial measurements of N-Terminal Pro-Brain Natriuretic Peptide in patients with coronary heart disease.
PLoS One 2015; 10:e0117143.

Braig S, Brandt S, Wabitsch M, Florath I, Brenner H, Rothenbacher D, Genuneit J.
Age-specific influence of wheezing phenotypes on preadolescent and adolescent health-related quality of life.
Pediatric Allergy and Immunology 2015; 25:781-787.

Breitling LP.
Smoking as an effect modifier of the association of calcium intake with bone mineral density.
Journal of Clinical Endocrinology and Metabolism 2015; 100:326-635.

Stock C, Uhlmann L, Hoffmeister M, Laux G, Kieser M, Brenner H.
Identification of physicians with unusual performance in screening colonoscopy databases: a Bayesian approach.
Gastrointestinal Endoscopy 2015; 81:646-654.

Kabisch M, Lorenzo Bermejo J, Dünnebier T, Ying S, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Hamann U.
Inherited variants in the inner contromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER negative breast cancer.
Carcinogenesis 2015; 36:256-271.

Painter JN, O'Mara TA, Batra J, ..., Brenner H, Dieffenbach AK, ..., Edwards SL, Thompson DJ, Spurdle AB.
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
Human Molecular Genetics 2015; 24:1478-1492.

Yang R, Pfütze K, Zucknick M, Sutter C, Wappenschmidt B, Marma F, Qu B, Cuk K, Engel C, Schott S, Schneeweiss A, Brenner H, Claus R, Plass C, Bugert P, Hoth M, Sohn C, Schmutzler R, Bartram CR, Burwinkel B.
DNA methylation array analyses identified breast cancer associated HYAL2 methylation in peripheral blood.
International Journal of Cancer 2015; 136:1845-1855.

Bläker H, Hildebrandt B, Riess H, von Winterfeld M, Ingold-Heppner B, Roth W, Kloor M, Schirmacher P, Dietel M, Tao S, Jansen L, Chang-Claude J, Ulrich A, Brenner H, Hoffmeister M.
Lymph node count and prognosis in colorectal cancer: the influence of examination quality.
International Journal of Cancer 2015; 136:1957-1966.

Bickeböller M, Tagscherer K, Kloor M, Jansen L, Chang-Claude J, Brenner H, Hoffmeister M, Toth C, Schirmacher P, Roth W, Bläker H.
Functional characterization of the tumor suppressor MARCKS in colorectal cancer and its association with survival.
Oncogene 2015; 34:1150-1159.

Bozorgmehr K, San Sebastian M, Brenner H, Razum O, Maier W, Saum KU, Holleczek B, Miksch A, Szecsenyi J.
Analysing horizontal equity in enrolment in Disease Management Programmes for coronary heart disease in Germany 2008 - 2010.
International Journal for Equity in Health 2015; 14:28.

Jansen L, Castro F, Gondos A, Krilaviciute A, Barnes B, Eberle A, Emrich K, Hentschel S, Holleczek B, Katalinic A, Brenner H for the GEKID Cancer Survival Workgroup.
Recent cancer survival in Germany: an analysis of common and less common cancers.
International Journal of Cancer 2015; 136:2649-2658.

Allemani C, Weir HK, ..., Tucker TC, Coleman MP, Concord Working Group*.
Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,877 patients from 279 population-based registries in 67 countries (CONCORD-2).
The Lancet 2015; 385:977-1010.
*Member of the CONCORD Working Group from DKFZ: Brenner H.

Heiss JA, Brenner H.
Between-array normalization for 450K data.
Frontiers in Genetics 2015; 6:92.

Brandt S, Moß A, Koenig W, Rothenbacher D, Brenner H, Wabitsch M.
Intrafamilial  associations of cardiometabolic risk factors - results of the Ulm Birth Cohort Study.
Atherosclerosis 2015; 240:174-183.

Nan H, Hutter CM, Lin Y, Jacobs EJ, Ulrich CM, White E, Baron JA, Berndt SI, Brenner H, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Casey G, Chang-Claude J, Chanock SJ, Cotterchio M, Duggan D, Figueiredo JC, Fuchs CS, Giovannucci EL, Gong J, Haile RW, haarrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hudson TJ, Jenkins MA, Jiao S, Lindor NM, Lemire M, Le Marchand L, Newcomb PA, Ogino S, Pflugeisen BM, Potter JD, Qu C, Rosse SA, Rudolph A, Schoen RE, Schumacher FR, Seminara D, Slattery ML, Thibodeau SN, Thomas F, Thornquist M, Warnick GS, Zanke BW, Gauderman J, Peters U Hsu L, Chan AT; for the CCFR and GECCO.
Association of Aspirin and NSAID use with risk of colorectal cancer according genetic variants.
JAMA 2015; 313:1133-1142.

Michailidou K, Beesley J, Lindstrom S, Canisius S, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Hall P, Easton DF.
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
Nature Genetics 2015; 47:373-381.

Stegeman S, Amankwah E, Klein K, O'Mara TA, Kim D, Lin HY, Permuth-Wey J, Sellers TA, Srinivasan S, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pharoah P, Khaw KT, Standford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Kaneva R, Teixeria MR, Consortium P, Bioresource AP, Spurdle AB, Clements JA, Park JY, Batra J.
A large scale analysis of genetic variants within putative miRNA binding sites in prostate cancer.
Cancer Discovery 2015; 5:368-379.

Brenner H, Altenhofen L, Stock C, Hoffmeister M.
Prevention, early detection, and overdiagnosis of colorectal cancer within 10 years of screening colonoscopy in Germany.
Clinical Gastroenterology and Hepatology 2015; 13:717-723.

Emrich IE, Pickering J, Schöttker B, Lennartz CS, Rogacev KS, Brenner H, Rothenbacher D, Holleczek B, Saum KU, Fliser D, Heine GH.
Comparison of the performance of two GFR Estimating Equations using creatinine and cystatin C to predict adverse outcomes in elderly individuals.
Americal Journal of Kidney Diseases 2015; 65:632-638.

Schöttker B, Saum KU, Jansen EHJM, Boffetta P, Trichopoulou A, Holleczek B, Dieffenbach AK, Brenner H.
Oxidative stress markers and all-cause mortality at older age. A population-based cohort study.
Journal of Gerontology: Medical Sciences 2015; 70:518-524.

Nagelhout GE, Willemsen MC, de Vries H, Mons U, Hitchman SC, Kunst AE, Guignard R, Siahpush M, Yong HH, van den Putte B, Fong GT, Thrasher JF.
Educational differences in the impact of pictorial cigarette warning labels on smokers: findings from the International Tobacco Control (ITC) Europe surveys.
Tobacco Control (published Online First, 14 April 2015).

Brenner H.
Colorectal cancer screening for older adults.
BMJ 2015; 350:h2029.

Mons U, Müezzinler A, Gellert C, Schöttker B, Abnet CC, Bobak M, de Groot L, Freedman ND, Jansen E, Kee F, Kromhout D, Kuulasmaa K, Laatikainen T, O'Doherty MG, Bueno-de-Mesquita B, Orfanos P, Peters A, van der Schouw YT, Wilsgaard T, Wolk A, Trichopoulou A, Bofetta P, Brenner H, on behalf of the CHANCES consortium.
Impact of smoking and smoking cessation on cardiovascular events and mortality among older adults - Meta-analysis of individual participant data from prospective cohort studies of the CHANCES consortium.
British Medical Journal 2015; 350:h1551.

Orr N, Dudbridge F, Dryden N, ..., Brenner H, Dieffenbach AK, Arndt V, ..., dos Santos Silva I, Fletcher O, Peto J.
Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.
Human Molecular Genetics 2015; 24:2966-2984.

Song M, Gong J, Giovannucci EL, ..., Brenner H, Chang-Claude J, ..., Hoffmeister M, ..., Jensen M, Peters U, Chan AT.
Genetic variants of adiponectin and risk of colorectal cancer.
International Journal of Cancer 2015; 137:154-164.

Laitinen VH, Rantapero T, Fischer D, Vuorinen EM, Tammela TLJ, PRACTICAL Consortium*, Wahlfors T, Schleutker J.
Fine-mapping the 2q37 and 17q11.2-q22 loci for novel genes and sequence variants associated with a genetic predisposition to prostate cancer.
International Journal of Cancer 2015; 136:2316-2327.
*Author on behalf of the ESTHER study: Brenner H.

Pirie A, Guo Q, Kraft P, Canisius S, Eccles DM, ..., Brenner H, Butterbach K, Arndt V, ..., Fasching PA, Pharoah PDP, Schmidt MK.
Common germline polymorphisms associated with breast cancer specific survival.
Breast Cancer Research 2015; 17:58.

Perna L, Wahl HW, Mons U, Saum KU, Holleczek B, Brenner H.
Cognitive impairment, all-cause and cause-specific mortality among non-demented older adults.
Age and Ageing 2015; 44:445-451.

Panagiotou OA, Travis RC, Campa D, Berndt SI, Lindstrom S, Kraft P, Schumacher FR, Siddiq A, Papatheodourou SI, Stanford JL, Albanes D, Virtamo J, Weinstein SJ, Diver WR, Gapstur SM Stevens VL, Boeing H, Bas Bueno-de- Mesquita H, Barricarte Guerrea A, Kaaks R, Khaw KT, Krogh V, Overvad K, Riboli E, Trichopoulos D, Giovannucci E, Stampfer M, Haiman c, Henderson B, Le Marchand L, Gaziano JM, Hunter DJ, Koutros S, Yeager M, Hoover RN, The PRACICAL Consortium*, Chanock SJ, Wacholder S, Key TJ, Tsilidis KK.
A genome-wide pleiotropy scan for prostate cancer risk.
European Urology 2015; 67:649-657.
*Author on behalf of the ESTHER study: Brenner H.

Schöttker B, Brenner H.
Vitamin D as a resilience factor, helpful for survival of potentially fatal conditions. A hypothesis emerging from recent findings of the ESTHER cohort study and the CHANCES consortium.
Nutrients 2015; 7:3264-3278.

Pulte D, Jansen L, Brenner H.
Survival disparities by insurance type for patients age 15-64 with Non-Hodgekin Lymphoma.
The Oncologist 2015; 20:554-561.

Chen H, Chen XZ, Waterboer T, Castro FA, Brenner H.
Viral infections and colorectal cancer: a systematic review of epidemiological studies.
International Journal of Cancer 2015; 137:12-24.

Werner S, Chen H, Tao S, Brenner H.
Systematic Review: Serum autoantibodies in the early detection of gastric cancer.
International Journal of Cancer 2015; 136:2243-2252.

Zeissig SR, Singer S, Koch L, Zeeb H, Merbach M, Bertram H, Eberle A, Schmid-Höpfner S, Holleczek B, Waldmann A, Arndt V.
Utilisation of psychosocial and informational services in immigrant and non-immigrant German cancer survivors.
Psycho-Oncology 2015; DOI:10.1002/pon.3742.

Zeissig SR, Singer S, Koch L, Blettner M, Arndt V für die CAESAR Studiengruppe.
Inanspruchnahme psychoonkologischer Versorgung im Krankenhaus und in der Krebsberatungsstelle durch Brust-, Darm- und Prostatakrebsüberlebende.
Psychotherapie-Psychosomatik-Medizinische Psychologie 2015; 65:177-182.

Hsu L, Jeon J, Brenner H, Gruber SB, Schoen RE, Berndt SI, Chan AT, Chang-Claude J, Du M, Gong J, Harrison TA, Hayes RB, Hoffmeister M, Hutter CM, Lin Y, Nishihara R, Ogino S, Prentice RL, Schumacher FR, Seminara D, Slattery ML, Thomas DC, Thornquist M, Newcomb PA, Potter JD, Zheng Y, White E, Peters U on behalf of the Colorecal Transdisciplinary (CORECT) Study and Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO).
A model to determine colorectal cancer risk using common genetic susceptibility loci.
Gastroenterology 2015; 148:1330-1339.

Brenner H, Altenhofen L, Stock C, Hoffmeister M.
Expected long-term impact of the German screening colonoscopy program on colorectal cancer prevention: analyses based on 4,407,971 screening colonoscopies.
European Journal of Cancer 2015; 51:1346-1353.

Hoffmeister M, Jansen L, Rudolph A, Toth C, Kloor M, Roth W, Bläker H, Chang-Claude J, Brenner H.
Statin use and survival after colorectal cancer: the importance of comprehensive confounder adjustment.
Journal of the National Cancer Institute 2015; 107:djv045.

Benetou V, Orfanos P, Feskanich D, Michaelsson K, Pettersson-Kymmer U, Ahmed L, Peasey A, Wolk A, Brenner H, Bobak M, Wilsgaard T, Schöttker B, Saum KU, Bellavia A, Grodstein F, Klinaki E, Valanou E, Papatesta HM, Boffetta P, Trichopoulou A.
Education, martial status and risk of hip fractures in older men and women: the CHANCES project.
Osteoporosis International 2015; 26:1733-1746.

Brown AK, Nagelhout GE, van den Putta B, Willemsen MC, Mons U, Guignard R, Thompson ME.
Trends and socioeconomic differences in roll-your-own tobacco use: findings from the ITC Europe Surveys.
Tobacco Control 2015; 24:iii11-iii16.

König HH, Lehnert T, Brenner H, Schöttker B, Quinzler R, Haefeli WE, Matschinger H. Heider D.
Health service use and costs associated with excess weight in older adults in Germany.
Age and Ageing 2015; 44:616-623.

Sobral-Leite M, Wesseling J, Smit V, Nevanlinna H, van Miltenburg MH, ..., Brenner H, Butterbach K, Arndt V, Holleczek B, ..., García-Closas M, de Graauw M, Schmidt MK.
Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis.
BMC Medicine 2015; 13:156.

Schumacher F, Schmit S, Jiao S, Edlund C, Wang H, ..., Butterbach K, ..., Brenner H, ... Hoffmeister M, ..., Casey G, Gruber S, Peters U.
Genome-wide association study of colorectal cancer identifies six new susceptibility loci.
Nature Communication 2015; 6:7138.

The Emerging Risk Factors Collaboration.*
Association of cardiometabolic multimorbidity with mortality.
JAMA 2015; 314:52-60.
* Author on behalf of the ESTHER study: Brenner H.

Al Olama AA, Benlloch S, Antoniou AC, Giles GG, Severi G, Neal D, Hamdy FC, Donovan JL, Muir K, Schleutker J, Henderson BE, Haiman C, Schumacher FR, Pashayan N, Pharoah PD, Ostrander EA, Stanford JL, Batra J, Clements JA, Chambers SK, Weischer M, Nordestgaard BG, Ingles SA, Sorensen KD, Orntoft TF, Park JY, Cybulski C, Maier C, Doerk T, Dickinson JL, Cannon-Albright L, Brenner H, Rebbeck TR, Zeigler -Johnson C, Habuchi T, Thibodeau SN, Cooney K, Chappius PO, Hutter P, Kaneva RP, Foulkes WD, Zeegers MP, Lu YJ, Zhang HW, Stephenson R, Cox A, Southey MC, Spurdle AB, FitzGerald L, Leongamornlert D, Saunders E, Tymrakiewicz M, Guy M, Dadaev T, Little SJ, Govindasami K, Sawyer E Wilkinson R, Herkommer K, Hopper JL, Lophatonanon A, Rinckleb AE, Kote-Jarai Z, Eeles RA, Easton DF.
Risk analysis of prostate cancer in PRACTICAL, a multinational consortium, using 25 unknown prostate cancer susceptibility loci.
Cancer Epidemiology, Biomarkers and Prevention 2015; 24:1121-1129.

Darabi H, McCue K, Beesley J, Michailidou K, ..., Brenner H, ..., Arndt V, ..., Dunning AM, Easton DF, Hall P, Cevenix-Trench G.
Polymorphisms in a putative enhancer at the 10q21.2 breast cancer risk locus regulate NRBF2 expression.
American Journal of Human Genetics 2015; 97:22-34.

Thrift AP, Gong J, Peters U, Chang-Claude J, Rudolph A, Slattery ML, Chan AT, Locke AE, Kahali B, Justice AE, Pers TH, Gallinger S, Hayes RB, Baron JA, Caan BJ, Ogino S, Berndt SI, Chanock SJ, Casey G, Haile RW, Du M, Harrison TA, Thornquist M, Duggan DJ, Le Marchand L, Lindor NM, Seminara D, Song M, Wu K, Thibodeau SN, Cotterchio M, Win AK, Jenkins MA, Hopper JL, Ulrich CM, Potter JD, Newcomb PA, Hoffmeister M, Brenner H, White E, Hsu L, Campbell PT.
Mendelian randomization study of body mass index and colorectal cancer risk.
Cancer Epidemiology, Biomarkers and Prevention 2015; 24:1024-1031.

Walter V, Jansen L, Hoffmeister M, Ulrich A, Chang-Claude J, Brenner H.
Smoking and survival of colorectal cancer patients: population-based study from Germany.
International Journal of Cancer 2015; 137:1433-1445.

Chen H, Zucknick M, Werner S, Brenner H.
Head-to head comparison and evaluation of 92 plasma protein biomarkers for early detection of colorectal cancer in a true screening setting.
Clinical Cancer Research 2015; 21:3318-3326.

Breitling LP.
Calcium intake and bone mineral density as an example of non-linearity and threshold analysis.
Osteoporosis International 2015; 26:1271-1281.

Schöttker B, Zhang Y, Heiss JA, Butterbach K, Jansen EHJM, Bewerunge-Hudler M, Saum KU, Holleczek B, Brenner H.
Discovery of a novel epigenetic cancer marker related to the oxidative status of human blood.
Genes Chromosomes and Cancer 2015; 54:583-594.

Gondos A, Krilaviciute A, Smailyte G, Ulys A, Brenner H.
Cancer surveillance using registry data: results and recommendations for the Lithuanian national prostate cancer early detection programme.
European Journal of Cancer 2015; 51:1630-1637.

Zhang Y, Schöttker B, Ordonez-Mena J, Holleczek B, Yang R, Burwinkel B, Butterbach K, Brenner H.
F2RL3 methylation, lung cancer incidence and mortality.
International Journal of Cancer 2015; 137:1739-1748.

Brenner H, Altenhofen L, Kretschmann J, Rösch T, Pox C, Stock C, Hoffmeister M.
Trends in adenoma detection rates during the first 10 years of the German screening colonoscopy program.
Gastroenterology 2015; 149:356-366.

Müezzinler A, Mons U, Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H, Boukamp P, Holleczek B, Stegmaier B, Brenner H.
Smoking habits and leukocyte telomere length dynamics among older adults: Results from the ESTHER cohort.
Experimental Gerontology 2015; 70:18-25.

Szulkin R, Whitington T, Eklund M, Aly M, Eeles RA, ..., Brenner H, Butterbach K, Stegmaier C, ..., the PRACTICAL consortium, Gronberg H, Wiklund F.
Prediction of individual genetic risk to prostate cancer using a polygenic score.
The Prostate 2015; 75:1467-1474.

Freigofas J, Seidling HM, Quinzler R, Schöttker B, Saum KU, Brenner H, Haefeli WE.
Characteristics of medication schedules used by elderly ambulatory patients.
European Journal of Clinical Pharmacology 2015; 71:1109-1120.

Childs EJ, Mocci E, Campa D, Bracci PM, Gallinger S, Goggins MG, Li D, Neale R, Olson SH, Scelo G, Bamlet WR, Bijlsma M, Blackford A, Borges M, Brennan P, Brenner H, Bueno-de-Mesquita HB, Canzian F. Capurso G, Cavestro GM, Chaffee KG, Cleary SP, Cotterchio M, Foretova L, Funel N, Gazouli M, Hassan M, Holcatova I, Holly EA, Janout V, Key TJ, Kupcinskas J, Kurtz RC Landi S, Lu L, Malecka-Panas E, Mambrini A, Mohelnikova-Duchonova B, Neoptolemos JP, Oberg AL, Orlow I, Pasquali C, Pezzilli R, Rizzato C, Saldia A,  Scarpa A, Strobel O, Tavano F, Vashist YK, Vodicka P, Yu H, Petersen GM, Risch H, Klein AP.
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
Nature Genetics 2015; 47:911-916.

Kahlert C, Lerbs T, Pecqueux M, Herpel E, Hoffmeister M, Jansen L, Brenner H, Chang-Claude J, Bläker H, Kloor M, Roth W, Pilarsky C, Rahbari NN, Schölch S, Bork U, Reissfelder C, Weitz J, Aust D, Koch M.
Overexpression of SIX1 is an independent prognostic marker in stage I - III colorectal cancer.
International Journal of Cancer 2015; 137:2104-2113.

Campa D, Rizzato C, Stolzenberg-Solomon R, Pacetti P, Vodicka P, Cleary S, Capurso G, Bas Bueno-de-Mesquita H, Werner J, Gazouli M, Butterbach K, Ivanauskas A, Giese N, Petersen GM, Fogar P, Wang Z, Bassi C, Ryska M, Theodoropoulos GE, Kooperberg C, Hassan M, Greenhalf W, Pasquali C, Hackert T, Fuchs C, Mohelníková-Duchoñová B, Sperti C, Funel N, Dieffenbach AK, Wareham NJ, Buring J, Holcátová I, Costello-Goldring E, Zambone C-F, Kupcinskas J, Risch HA, Kraft P, Bracci PM, Pezzilli R, Olson SH, Sesso H, Hartge P, Strobel O, Malecka-Panas E, Visvanathan K, Arslan AA, Pedrazzoli S, Sucek P, Gioffreda D, Key TJ, Talar-Wojnarowska R, Scarpa A, Mambrini A, Jacobs EJ, Jamroziak K, Klein A, Tavano F, Bambi F, Landi S, Austin MA, Vodickova L, Brenner H, Chanock SJ, Delle Fave G, Piepoli A, Cantore M, Zheng W, Wolpin B, Amundadottir L, Canzian F.
The TERT gene harbors multiple variants associated with pancreatic cancer susceptibility.
International Journal of Cancer 2015; 137:2175-2183.

Boehlen F, Herzog W, Quinzler R, Haefeli WE, Maatouk I, Niehoff D, Saum KU, Brenner H, Wild B.
Loneliness in the elderly is associated with the use of psychotropic drugs.
International Journal of Geriatric Psychiatry 2015; 30:957-964.

Rothenbacher D, Jaensch A, Mons U, Hahmann H, Becker T, Koenig W, Brenner H.
Prognostic value of one-year course of symptoms of anxiety and depression in patients with coronary heart disease: role of physical activity and unmet medical need.
European Journal of Preventive Cardiology 2015; 22:1129-1138.

Candido do Reis FJ, Lynn S, Ali HR, Eccles D, Hanby A, Provenzano E, Caldas C, Howqat WJ, McDuffus LA, Liu B, Daley F, Coulson P, Vyas RJ, Harris LM, Owens JM, Carton AFM, McQuillan JP, Paterson AM, Hirji Z, Christie SK, Holmes AR, Schmidt MK, Garcia-Closas M, Easton DF, Bolla MK, Wang Q, Benitez J, Milne RL, Mannermaa A, couch F, Defilee P, cox A, Cross SS, Blows FM, Sanders J, de Groot R, Figueroa J, Sherman M, Hooning M, Brenner H, Holleczek B, Stegmaier C, Lintott C, Pharoah PDP for the Citizen Science Alliance.
Croudsourcing the general public for large scale molecular pathology studies in cancer.
EBioMedicine 2015; 2:681-689.

Meid AD, Quinzler R, Feigofas J, Saum K-U, Schöttker B, Holleczek B, Heider D, König H-H, Brenner H, Haefeli WE.
Medication underuse in aging outpatients with cardiovascular disease: prevalence, determinants, and outcomes in a prospective cohort study.
PLoS One 2015;10:e0136339.

Surinova S, Choi M, Tao S, Schüffler PJ, Chang CY, Clough T, Vyslouzil K, Khoylou M, Srovnal J, Liu Y, Matondo M, Hüttenhain R, Weisser H, Buhmann JM, Hajdúch M, Brenner H, Vitek O, Aebersold R.
Prediction of colorectal cancer diagnosis based on circulating plasma proteins.
EMBO Molecular Medicine 2015; 7:1166-1178.

Surinova S, Radová L, Choi M, Srovnal J, Brenner H, Vitek O, Hajdúch M,  Aebersold R.
Non-invasive prognostic protein biomarker signatures associated with colorectal cancer.
EMBO Molecular Medicine 2015; 7:1153-1165.

Khalili H, Gong J, Brenner H, Austin TR, Hutter CM, Baba Y, Baron JA, Berndt SI, Bézieau S, Caan B, Campbell PT, Chang-Claude J, Chanock SJ, Chen C, Hus L, Jiao S, Conti DV, Duggan D, Fuchs CS, Gala M, Gallinger S, Haile RW, Harrison TA, Hayes R, Hazra A, Henderson B, Haiman C, Hoffmeister M, Hopper JL, Jenkins MA, Kolonel LN, Küry S, LaCroix A, le Marchand L, Lemire M, Lindor NM, Ma J, Manson JE, Morikawa T, nan H, Ng K, Newcomb PA, Nishihara R, Potter JD, Qu C, Schoen RE, Schumacher FR, Seminara D, Taverna D, Thibodeau S, Wactawski-Wende J, White E, Wu K, Zanke BW, Casey G, Hudson TJ, Kraft P, Peters U, Slattery ML, Ogino S, Chan AT on behalf of GECCO and CCFR.
Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer.
Carciogenesis 2015; 36:999-1007.

Saum KU, Dieffenbach AK, Jansen EHJM, Schöttker B, Holleczek B, Hauer K, Brenner H.
Association between oxidative stress and frailty in an elderly German population: results from the ESTHER cohort study.
Gerontology 2015; 61:407-415.

Guo Q, Schmidt MK, Kraft P, Canisius S, ..., Brenner H, Dieffenbach AK, Arndt V, ..., Pharoah PDP.
Identification of novel genetic markers of breast cancer survival.
Journal of the National Cancer Institute 2015; 107:djv081.

Chen LS, Hung RJ, Baker T, Horton A, Culverhouse R, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kin C, Lutz S, Rosenberger A, Aben KK, Andrew AS, Breslau N, Chang SC, Dieffenbach AK, Dienemann H, Frederiksen B, Han J, Hatsukami DK, Johnson EO, Pande M, Wrensch MR, McLaughlin J, Skaug V, van der Heijden HF, Wampfler J, Wenzlaff A, Woll P, Zienolddiny S, Bickeböller H, Brenner H, Duell EJ, Haugen A, Heinrich H, Hokanson JE, Hunter DJ, Kiemeney LA, Lazarus P, Le Marchand L, Liu G, Mayordomo J, Risch A, Schwartz AG, Teare D, Wu X, Wiencke JK, Yang P,  Zhang ZF, Spitz MR, Kraft P, Amos CI, Bierut LJ.
CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis - a meta-analysis.
Journal of the National Cancer Institute 2015; 107:djv100.

Dworschak GC, Draaken M, Hilger AC, Schramm C, Bartels E, Schmiedeke E, Grasshoff-Derr S, Märzheuser S, Holland-Cunz S, Lacher M, Jenetzky E, Zwink N, Schmidt D, Nöthen MM, Ludwig M, Reutter H.
Genome-wide mapping of copy number variations in patients with both anorectal malformations and central nervous system abnormalities.
Birth Defects Research Part A: Clinical and Molecular Teratology 2015; 103:235-242.

Draaken M, Knapp M, Pennimpede T, Schmidt JM, Ebert AK, Rösch W, Stein R, Utsch B, Hirsch K, Boemers TM, Mangold E, Heilmann S, Ludwig KU, Jenetzky E, Zwink N, Moebus S, Herrmann BG, Mattheisen M, Nöthen MM, Ludwig M, Reutter H.
Genome-wide association study and meta-analysis identify ISL1 as genome-wide significant susceptibility gene for bladder exstrophy.
PLoS Genetics 2015; 11:e1005024.

Springvloet L, Willemsen MC, Mons U, van den Putte B, Kunst AE, Guignard R, Hummel K, Allwright S, Siahpush M, de Vries H, Nagelhout GE.
Educational differences in associations of noticing anti-tobacco information with smoking-related attitudes and quit intentions: findings from the International Tobacco Control Europe Surveys.
Health Education Research 2015; 30:719-730.

Rothenbacher D, Dallmeier D, Mons U, Rosamond W, Koenig W, Brenner H.
Sexual activity patterns before myocardial infarction and risk for subsequent cardiovascular adverse events.
JACC 2015; 66:1516-1517.

Brenner H.
Mortality from malignant melanoma in an era of nationwide skin cancer screening.
Deutsches Ärzteblatt 2015; 112:627-628.

Anderson LA, Tavilla A, Brenner H, Luttmann S, Navaro C, Gavin AT, Holleczek B, Johnston BT, Cook MB, Bannon f, Sant M, EUROCARE-5 Working Group.
Survival for oesophageal, stomach and small intestine cancers: results from EUROCARE-5.
European Journal of Cancer 2015; 51:2144-2157.

Holleczek B, Rossi S, Domenic A, Innos K, Minicozzi P, Francisci S, Hackl M, Eisemann N, Brenner H, and the EUROCARE-5 Working Group.
On-going improvement and persistent differences in the survival for patients with colon and rectum cancer across Europe - results from the EUROCARE-5 study.
European Journal of Cancer 2015; 51:2158-2168.

Rossi S, Baili P, Capocaccia R, Caldora M, Carrani E, Minicozzi P, Pierannunzio D, Santaquilani M, Trama A, Allemani C, Belot A, Buzzoni C. Lorez M, De Angelis R, and the EUROCARE-5 Working Group*.
The EUROCARE-5 study on cancer survival in Europe 1999-2007: Database, quality checks and statistical analysis methods.
European Journal of Cancer 2015; 51:2104-2119.
*Member from DKFZ: Brenner H.

Baili P, Di Salvo F, Marcos-Gragera R, Siesling S, Mallone S, Santaquilani M, Micheli A, Lillini R, Francisci S, and the EUROCARE-5 Working Group*.
Age and case mix-standardised survival for all cancer patients in Europe 1999-2007: Results of EUROCARE-5, a population-based study.
European Journal of Cancer 2015; 51:2120-2129.
*Member from DKFZ: Brenner H.

Gatta G, Botta L, Sánchez MJ, Anderson LA, Pierannunzio D, Licitra L, and the EUROCARE-Working Group*.
Prognoses and improvement for head and neck cancers diagnosed in Europe in early 2000s: The EUROCARE-5 population-based study.
European Journal of Cancer 2015; 51:2130-2143.
*Member from DKFZ: Brenner H.

Lepage C, Capocaccia R, Hackl M, Lemmens V, Molina E, Pierannunzio D, Sant M, Trama A, Faivre J, and the EUROCARE-5 Working Group*.
Survival in patients with primary liver cancer, gallbladder and extrahepatic biliary tract cancer and pancreatic cancer in Europe 1999-2007: Results of EUROCARE-5.
European Journal of Cancer 2015; 51:2169-2178.
*Member from DKFZ: Brenner H.

Crocetti E, Mallone S, Robsahm TE, Gavin A, Agius D, Ardanaz E, Lopez MDC, Innos K, Minicozzi P, Borgognoni L, Pierannunzio D, Eisemann N, and the EUROCARE-5 Working Group*.
Survival of patients with skin melanoma in Europe increases further: Results of the EUROCARE-5 study.
European Journal of Cancer 2015; 51:2179-2190.
*Member from DKFZ: Brenner H.

Sant M, Chirlaque Lopez MD, Agresti R, Sánchez Pérez MJ, Holleczek B, Bielska-Lasota M, Dimitrova N, Innos K, Katalinic A, Langseth H, Larrañaga N, Rossi S, Siesling S, Minicozzi P, The EUROCARE-5 Working Group*.
Survival of women with cancers of breast and genital organs in Europe 1999-2007: Results of the EUROCARE-5 study.
European Journal of Cancer 2015; 51:219-2205.
*Member from DKFZ: Brenner H.

Trama A, Foschi R, Larrañaga N, Sant M, Fuentes-Raspall R, Serraino D, Tavilla A, Van Eycken L, Nicolai N, and the EUROCARE-5 Working Group*.
Survival of male genital cancers (prostate, testis and penis) in Europe 1999-2007: Results from the EUROCARE-5 study.
European Journal of Cancer 2015; 51:2206-2216.
*Member from DKFZ: Brenner H.

Marcos-Gragera R, Mallone S, Kiemeney LA, Vilardell L, Malats N, Allory Y, Sant M, and the EUROCARE-5 Working Goup*.
Urinary tract cancer survival in Europe 1999-2007: Results of the population-based study EUROCARE-5.
European Journal of Cancer 2015; 51:2217-2230.
*Member from DKFZ: Brenner H.

Visser O, Ardanaz E, Botta L, Sant M, Tavilla A, Minicozzi P, The EUROCARE-5 Working Group*.
Survival of adults with primary malignant brain tumours in Europe; Results of the EUROCARE-5 study.
European Journal of Cancer 2015; 51:2231-2241.
*Member from DKFZ: Brenner H.

Francisci S, Minicozzi P, Pierannunzio D, Ardanaz E, Eberle A, Grinsrud TK, Knijn A, Pastorino U, Salmerón D Trama A, Sant M, and the EUROCARE-5 Working Group*.
Survival patterns in lung and pleural cancer in Europe 1999-2007: Results from the EUROCARE-5 study.
European Journal of Cancer 2015; 51:2242-2253.
*Member from DKFZ: Brenner H.

De Angelis R, Minicozzi P, Sant M, Dal Maso L, Brewster DH, Osca-Gelis G, Visser O, Maynadié M, Marcos-Gragera R, Troussard X, Agius D, Roazzi P, Meneghini E, Monnereau A, and the EUROCARE-5 Working Group*.
Survival variations by country and age for lymphoid an myeloid malignancies in Europe 2000-2007: Results of EUROCARE-5 population-based study.
European Journal of Cancer 2015; 51:2254-2268.
*Member from DKFZ: Brenner H.

Gao X, Jia M, Zhang Y, Breitling LP, Brenner H.
DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies.
Clinical Epigenetics 2015; 7:113.

Brenner H, Stock C, Hoffmeister M.
Colorectal cancer screening: the time to act is now.
BMC Medicine 2015; 13:262.

Davies NM, Gaunt TR, Lewis SJ, Holly J, Donovan JL, Hamdy FC, Kemp JP, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neals D, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, PRACTICAL Consortium, Lathrop M, Smith GD, Martin MR.
The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium.
Cancer Causes Control 2015; 26:1603-1616.

O'Mara TA, Glubb DM, Painter JN, Cheng T, Dennis J, The Australian National Endometrial Cancer Study Group (ANECS), Attia J, Holliday EG, McEvoy M, Scott RJ, Ashton K, Proietto T, Otton G, Shah M, Ahmed S, Healey CS, Gorman M, Martin L, National Study of Endometrial Cancer Genetics Group (NSECG), Hodgson S, Fasching PA, Hein A, Beckmann MW, Ekici AB, Hall P, Czene K, Darabi H, Li J, Dürst M, Runnebaum I, Hillemanns P, Dörk T, Lambrechts D, Depreeuw J, Annibali D, Amant F, Zhao H, Goode EL, Dowdy SC,Fridley BL, Winham SJ, Salvesen HB, Njølstad TS, Trovik J, Werner HMJ, Tham E, Liu T, Mints M, RENDOCAS, Bolla MK, Michailidou K, Tyrer JP, Wang Q, Hopper JL, AOCS Group, Peto J, Swerdlow AJ, Burwinkel B, Brenner H, Meindl A, Brauch H, Lindblom A, Chang-Claude J, Couch FJ, Giles GG, Kristensen VN, Cox A, Pharoah PDP, Dunning AM, Tomlinson I, Easton DF, Thompson DJ, Spurdle AB.
Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer.
Endocrine-Related Cancer 2015; 22:851-861.

Bozorgmehr K, Maier W, Brenner H, Saum KU, Stock C, Miksch A, Holleczek B, Szecsenyi J, Razum O.
Social disparities in Disease Management Programmes for coronary heart disease in Germany: A cross-classified multilevel analysis.
Journal of Epidemiology & Community Health 2015; 69:1091-1101.

Al Olama AA, Dadaev T, Hazelett D, Li Q, Leongamornlert D, Saunders EJ, Stephens S, Cieza-Borella C, Whitmore I, Benlloch Garcia S, Giles GG, Southey MC, Pedersen J, Gronberg H, Wiklund F, Aly M, Henderson BE, Schumacher F, Haiman CA, Schleutker JL, Hamdy FC, Neal DE, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Holt S, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokozorczyk D, Kluzniak W, Cannon-Albright L, Brenner H, Dieffenbach AK, Arndt V, Park JY, Sellers T, Lim HY, Slavov C, Kaneva R, Batra J, Clements JA, Spurdle A, Teixeira MR, Paulo P, Maia S, Pandha H, Michael A, Kierzek A, Govindasami K, Guy M, Muir K, Viñuela A, Brown AA, The PRACTICAL Consortium, COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative, The UK Genetic Prostate Cancer Study Collaborators, The UK ProtecT Study Collaborators, Freedman M, Conti DV, Easton D, Cotzee G, Eeles RA, Kote-Jarai Z.
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.
Human Molecular Genetics 20115; 24:5589-5602.

Galeone C, Turati F, Zhang ZF, Guerico V, Tavani A, Serraino D, Brennan P, Fabianova E, Lissowska J, Mates D, Rudnai P, Shangina O, Szeszenia-Dabrowska N, Vaughan TL, Kelsey K, McClean M, Levi F, Hayes RB, Purdue MP, Bosetti C, Brenner H, Pelucchi C, Lee YCA, Hashibe M, Boffetta P, La Vecchia C.
Relation of allium vegetables intake with head and neck cancers: evidence from the INHANCE Consortium.
Molecular Nutrition and Food Research 2015; 59:1641-1650.

Castro FA, Jansen L, Krilaviciute A, Katalinic A, Pulte D, Sirri E, Ressing M, Holleczek B, Luttmann S, Brenner H, for the GEKID Cancer Survival Working Group.
Survival of patients with gastric lymphoma in Germany and the United States.
Journal of Gastroenterology and Hepatology 2015; 30:1485-1491.

Vart P, Bakker SJL, Schöttker B, de Zeeuw D, Rothenbacher D, Brenner H, Lambers Heerspink HJ, Saum KU, Reijneveld SA, Bültmann U, Koenig W, Gansevoort RT.
Relevance of correction for drift and day-to-day variation in cystatin C measurement: a post-hoc analysis of the PREVEND cohort, with independent replication in the ESTHER cohort..
Clinical Chemistry and Laboratory Medicine 2015; 53:1381-1390.

Matsushita K, Coresh J, Sang Y, Chalmers J, Fox C, Guallar E, Jafar T, Jassal SK, Landman GWD, Muntner P, Roderick P, Sairenchi T, Schöttker B, Shankar A, Shlipak M, Tonelli M, Townend J, van Zuilen A, Yamagishi K, Yamashita K, Gansevoort R, Sarnak M, Warnock DG, Woodward M, Ärnlöv J, for the CKD Prognosis Consortium*.
Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis.
Lancet Dieabetes & Endocrinology 2015; 3:514-525.
*Investigators and collaborators on behalf of the ESTHER study: Rothenbacher D, Brenner H, Müller H.

Thrift AP, Gong J, Peters U, Chang-Claude J, Rudolfph A, Slattery ML, Chan AT, Esko T, Wood AR, Yang J, Vendantam S, Gustafsson S, Pers TH, GIANT Consortium, Baron JH, Bezieau S, Küry S, Ogino S, Berndt SI, Casey G, Haile RW, Mangmang D, Harrison TA, Thornquist M, Duggan DJ, Le Marchand L, Lemire M, Lindor NM, Seminara D, Song M, Thibodeau SN, Cotterchio M, Win AK, Jenkins MA, Hopper JL, Ulrich CM, Potter JD, Newcomb PA, Schoen RE, Hoffmeister M, Brenner H, White E, Hsu L, Campbell PT.
Mendelian randomization study of height and risk of colorectal cancer.
International Journal of Epidemiology 2015; 44:662-672.

Perna L, Mons U, Rujescu D, Kliegel M, Brenner H.
Apolipoprotein E e4 and cognitive function: a modifiable association? Results from two independent cohort studies.
Dementia and Geriatric Cognitive Disorders 2015; 41:35-45.

Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, ..., Arndt V, ..., Brenner H, ..., Murabito JM, Perry JRB, Murray A.
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Nature Genetics 2015; 47:1294-1303.

Chen T, Fallah M, Jansen L, Castro FA, Krilaviciute A, Katalinic A, Emrich K, Holleczek B, Geiss K, Eberle A, Sundquist J, Brenner H, Hemminki H, for the GEKID Cancer Survival Working Group.
Distribution and risk of the second discordant primary cancers combined after a specific first primary cancer in German and Swedish cancer registries.
Cancer Letters 2015; 369:152-166.

Müezzinler A, Gellert C, Mons U, Schöttker B, Jansen E, Kee F, O'Doherty MG, Kuulasmaa K, Freedman ND, Abnet CC, Wolk A Håkansson N, Orsini N, Wilsgaard T, Njølstad I, Bøgeberg M, Leenders M, Bueno-de-Mesquita B, van der Schouw YT, Peeters PH, Streppel MT, de Groot LCPGM, Peters A, Schneider A, Orfanos P, Linneberg A, Pisinger C, Lorbeer R, Tamosiunas A, Baceviciene M, Luksiene D, Bernotiene G, Jousilahti P, Schaan B, Wennberg P, Petterson-Kymmer U, Jansson JH, Söderberg S, Eriksson S, jankovic N, Kromhout D, Geelen A, Sánchez M-J, Veronesi G, Trichopoulou A, Boffetta P, Brenner H.
Smoking and all-cause mortality in older adults - Results from CHANCES Consortium.
American Journal of Preventive Medicine 2015; 49:e53-e63.

Global Burden of Disease Study 2013 Collaborators*.
Global, regional, and national incidence, prevalence, and YLDs for 301 acute and chronic diseases and injuries for 188 countries, 1990-2013: a systematic analysis for the Global Burden of Diseases Study 2013.
The Lancet 2015; 386:743-800.
*Collaborators from DKFZ: Brenner H, Schöttker B.

Imhof A, Koenig W, Jaensch A, Mons U, Brenner H, Rothenbacher D.
Long-term prognostic value of lgM antibodies against phosphorylcholine for adverse cardiovascular events in patients with stable coronary heart disease.
Atherosclerosis 2015; 243:414-420.

Lemire M, Qu C, Loo LWM, Zaidi SHE, Wang H, Berndt SI, Bézieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Du M, Edlund CK, Gallinger S, Haile RW, Harrision TA, Hoffmeister M, Hopper JL, Hou L, Hsu L, Jacobs EJ, Jenkins MA, Jeon J, Küry S, Li L, Lindor NM, Newcomb PA, Potter JD, Rennert G, Rudolph A, Schoen RE, Schumacher FR, Seminara D, Severi G, Slattery ML, White E, Wood MO, Cotterchio M, Le Marchand L, Casey G, Gruber SB, Peters U, Hudson TJ.
A genome-wide association study for colorectal cancer identifies a risk locus in 14q23.1.
Human Genetics 2015; 134:1249-1262.

Guo X, Long J, Zeng C, Michailidou K, Ghoussaini M, ..., Arndt V, ..., Brenner H, ..., Dunning AM, Easton DF, Zheng W.
Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk.
Cancer Epidemiology, Biomarkers & Prevention 2015; 24:1680-1691.

Szulkin R, Karlsson R, Whitington T, Aly M, Gronberg H, Eeles RA, Easton DF, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, Southey MC, FitzGerald L, Henderson BE, Schumacher FR, Haiman CA, Sipeky C, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Neal D, Donovan JL, Hamdy FC, Pharoah PD, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Lubinski J, Kluzniak W, Cannon-Albright L, Brenner H, Herrmann V, Holleczek B, Park JY, Sellers TA, Lin HY, Slavoy C, Kaneva RP, Mitev VI, Batra J, Clements JA, Spurdle A, Teixeira MR, Paulo P, Maia S, Pandha HS, Michael A, Kierzek A, Albanes D, Andriole GL, Berndt SI, Chanock SJ, Gapstur SM, Giovannucci EL, Hunter DJ, Kraft P, Le Marchand L, Ma J, Mondul AM, Penney KL, Stampfer M, Stevens VL, Weinstein SJ, Trichopoulou A, Bueno-de-Mesquita HB, Tjonneland A, Cox DG, Maehle L, Schleutker J, Lindstrom S, Wiklund F.
Genome-wide association study of prostate cancer-specific survival.
Cancer Epidemiology, Biomarkers & Prevention 2015; 24:1796-1800.

Brenner H, Jansen L.
Restriction to period of interest improves informative value of death certificate only proportions in period analysis of cancer survival.
Journal of Clinical Epidemiology 2015; 68:1432-1439.

Brenner H, Altenhofen L, Stock C, Hoffmeister M.
Vorsorge-Koloskopie in Deutschland - Bilanz und Perspektiven.
Endoskopie heute 2015; 28:174-177.

Kap EJ, Seibold P, Richter S, Scherer D, Habermann N, Balavarca Y, Jansen L, Becker N, Pfuetze K, Popanda O, Hoffmeister M, Ulrich A, Benner H, Ulrich CM, Burwinkel B, Brenner H, Chang-Claude J.
Genetic variants in DNA repair genes as potential predictive markers for oxaliplatin chemotherapy in colorectal cancer.
The Pharmacogenomics Journal 2015; 15:505-512.

Cheng THT, Thompson D, Painter J, O'Mara T, Gorman M, ..., Brenner H, ..., Dunlop M, Houlston R, Spurdle A, Tomlinson I.
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal cancer and endometrial cancer near SH2B3 and TSHZ1.
Scientific Reports 2015; 5:17369.

Meyer ML, Jaensch A, Mons U, Breitling LP, Hahmann H, Koenig W, Brenner H, Rothenbacher D.
Atrial fibrillation and long-term prognosis of patients with stable coronary heart disease: relevance of routine electrocardiogram.
International Journal of Cardiology 2015;203:1014-1015.

Pfütze K, Benner A, Hoffmeister M, Jansen L, Yang R, Bläker H, Herpel E, Ulrich A, Ulrich CM, Chang-Claude J, Brenner H, Burwinkel B.
Methylation status at HYAL2 predicts overall and progression-free survival of colon cancer patients under 5-FU chemotherapy.
Genomics 2015; 106:348-354.

GBD 2013 DALYs and HALE Collaborators, Murray CJ, Barber RM, Foreman KJ, Ozgoren AA, ..., Brenner H, ..., Schöttker B, ..., Salomon JA, Lopez AD, Vos T.
Global, regional and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition.
The Lancet 2015; 386:2145-2191.

Jamshidi M, Fagerholm R, Khan S, Aittomäki K, ..., Brenner H, ... Hall P, Blomqvist C, Schmidt MK, Nevanlinna H.
SNP-SNP interaction analysis kB signaling pathway on breast cancer survival.
Oncotarget 2015; 6:37979-37994.

Krilaviciute A, Heiss JA, Leja M, Kupcinskas J, Haick H, Brenner H.
Detection of cancer through exhaled breath: a systematic review.
Oncotarget 2015; 6:38643-38657.

Schöttker B, Brenner H, Jansen EHJM, Gardiner J, Peasey A, Kubínová R, Pajak A, Topor-Madry R, Tamosiunas A, Saum KU, Holleczek B, Pikhart H, Bobak M.
Evidence for the Free Radical/Oxidative Stress Theory of Ageing from the CHANCES consortium: A meta-analysis of individual participant data.
BMC Medicine 2015; 13:300.

GDB 2013 Mortality and Causes of Death Collaborators*.
Global, regional and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the GBD 2013.
The Lancet 2015; 386:2287-2323.
*Collaborators from DKFZ: Brenner H, Schöttker B.

Jiao S, Peters U, Berndt S, Bézieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Lemire M, Newcomb PA, Potter JD; Slattery ML, Woods MO, Hsu L.
Powerful set-based gene-environment interaction testing framework for complex diseases.
Genetic Epidemiology 2015; 39:609-618.

Zhang B, Shu XO, Delahanty RJ, Zeng C, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Hunter DJ, Easton DF, Zheng W.
Height and breast cancer risk: Evidence from prospective studies and mendelian randomization.
Journal of the National Cancer Institute 2015; 107:djv219.

Eberle A, Jansen L, Krilaviciute A, Luttmann S, Emrich K, Holleczek B, Nennecke A, Katalinic A, Brenner H, for the GEKID Cancer Survival Working Group.
Lung cancer survival in Germany: a population-based analysis of 132,612 lung cancer patients.
Lung Cancer 2015; 90:528-533.

Pulte D, Jansen L, Castro FA, Emrich K, Katalinic A, Holleczek B, Brenner H, for the GEKID Cancer Survival Working Group.
Trends in survival of multiple myeloma patients in Germany and in the United States in the first decade of the 21st century.
British Journal of Haematology 2015;171:189-196.

Chen XZ, Chen H, Castro FA, Hu JK, Brenner H.
Epstein-Barr virus infection and gastric cancer - a systematic review.
Medicine 2015; 94(20):e792.

Haug U, Rösch T, Hoffmeister M, Katalinic A, Brenner H, Becker N.
Einführung eines organisierten Darmkrebs-Screenings in Deuschland: Chancen und Herausforderungen.
Das Gesundheitswesen 2015; 77:869-874.

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