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Defects in the packaging of genetic material in malignant brain tumors

Glioblastomas are regarded as particularly aggressive brain tumors. In children with glioblastoma, Heidelberg scientists have now discovered genetic alterations that affect the function of DNA packaging proteins known as histones. In a cell, histones serve as coils around which the DNA wraps. At the same time, histones regulate gene activity.

German Cancer Aid Award for Peter Krammer

Professor Dr. Peter Krammer of the German Cancer Research (Deutsches Krebsforschungszentrum, DKFZ) is awarded the 2011 German Cancer Aid Award (Deutscher Krebshilfe-Preis 2011) jointly with Professor Dr. Klaus Michael Debatin of Ulm University Hospitals. The award is given to the two scientists in recognition of their pioneering ...

Rigged to explode?

Inherited mutation links exploding chromosomes to cancer. An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology Laboratory (EMBL), the German Cancer Research Centre (DKFZ) and the University Hospital, all ...

last update: 30/01/2012 back to top