Joint Press Release

Epstein-Barr virus and cancer: new tricks from an old dog

Almost everybody has it: Scientists estimate that approximately 98 percent of adults around the world are infected with the Epstein-Barr virus. In rare cases, an infection with this virus causes cancer. Scientists at the German Cancer Research Center (DKFZ), at the German Center for Infection Research (DZIF), and at the French National Institute of Health and Medical Research (Inserm) have now discovered that a component of the Epstein-Barr virus infectious particle promotes carcinogenesis. This viral protein interferes with cell division and impairs proper distribution of the genetic material to the two daughter cells. This confers a risk of subsequent cancer development.

DKTK Berlin

The Variety of the Tumor in 3D

During its formation, every tumor receives a specific genetic profile, which can be utilized for personalized cancer therapy. But even within one tumor, various regions can develop which have distinct features. By making a three-dimensional tumor model, researchers at the German Cancer Consortium (DKTK) at the Charité Medical University of Berlin, at the Carl Gustav Carus University Hospital in Dresden, and at the Technical University in Munich, were able to show for the first time how cancer-relevant genes in colorectal cancer are amplified in specific tumor regions. The results could help to improve routine molecular diagnostics. The DKTK is made up of the German Cancer Research Center (DKFZ) in Heidelberg as the core location, along with renowned oncology departments of universities in various partner locations across Germany.

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Latest News

Immune System with a Timer

Scientists from the German Cancer Research Center and the Heidelberg University Hospital have discovered a previously unknown feedback mechanism of the human immune system. Their research shows how the innate immune system is quickly activated in the case of a viral infection, but is inhibited after just a few hours. This prevents an excessive immune reaction that might result in cell damage. The results of the study have been published in the journal "Molecular Cell."

World Cancer Day 2017

Cancer diagnosis from the blood

Can a simple blood sample test replace an invasive biopsy of tumor tissue? Can a few milliliters of blood make even mammography and colonoscopy unnecessary? What are the facts about the cancer blood test called liquid biopsy? On the occasion of World Cancer Day on February 4, experts from the German Cancer Research Center (DKFZ) report on the current state of research: What is already possible today and what can be expected of the cancer blood test in the near future?

Latest News

Lack of oxygen turns cancer cells into dangerous “sleeper cells”

For a long time it was considered an established fact that cervical cancer, which is caused by human papillomaviruses (HPV), depends on two specific viral proteins. If they are absent, the cancer cells stop growing permanently. Scientists at the German Cancer Research Center (DKFZ) have now discovered that cancer cells reduce the production of these viral proteins during hypoxia - a condition of oxygen deficiency that is very common in tumors. However, this does not lead to final growth cessation, but instead induces a state of dormancy from which the cancer cells can awaken and start proliferating again and may thus cause the cancer to return.

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Hopp Children’s Tumor Center (KiTZ)

“The chances of recovery for severely ill children are being further improved“

To commemorate the founding of the Hopp Children's Tumor Center at the NCT Heidelberg (KiTZ) by the Heidelberg University Hospital and the German Cancer Research Institute (DKFZ), the first Child Cancer Symposium in Heidelberg took place on January 19 and 20. The night before, the directors of the KiTZ invited representatives from the fields of science, politics, and economics to a reception at the Print Media Academy in Heidelberg. Among the speakers was the State Minister for Science, Research, and Art, Theresia Bauer, who described the Children's Tumor Center as a fantastic project with great potential due to the local conditions.

DKFZ-researcher receives ERC-Grant

Fatty acid from food as a signaling molecule for cell growth

ERC Consolidator Grants by the European Research Council (ERC) support excellent researchers to help them consolidate their independent careers. Aurelio Teleman from the German Cancer Research Center (DKFZ) recently received a Consolidator Grant, which is already the second prestigious ERC grant that he was able to attract. The grant comprising €2 million will enable Teleman to investigate how a fatty acid from food controls cellular growth as a signaling molecule and may even play a role in the development of cancer.

Meyenburg Prize 2016

Programmable gene scissors revolutionize life sciences

The Meyenburg Prize 2016 endowed with 50,000 Euros goes to the microbiologist Emmanuelle Charpentier from the Max Planck Institute for Infection Biology in Berlin. She receives the award for her breakthrough work in developing programmable "gene scissors". With this precision tool, genes can be processed simply and precisely. The Meyenburg Prize will be presented during a symposium at the German Cancer Research Center on Tuesday, 20 December 2016.

DKFZ - A Video

Research For A Life Without Cancer
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