Original- und Übersichtsarbeiten im Jahr 2014

Brenner H, Hoffmeister M, Jansen L.
Comparisons of colorectal cancer mortality between screening participants and the general population are strongly biased unless an incidence-based mortality approach is used.
Journal of Clinical Epidemiology 2014; 67:184-189.

De Angelis R, Sant M, Coleman MP, Francisci S, Baili P, Pierannunzio D, Trama A, Visser O, Brenner H, Ardanaz E, Bielska-Lasota M, Engholm G, Nennecke A, Siesling S, Berrino F, Capocaccia R; the EUROCARE-5 Working Group.
Cancer survival in Europe 1999-2007 by country and age: results of EUROCARE-5-a population-based study.
The Lancet Oncology 2014; 15:23-34.

Schoeps A, Rudolph A, Seibold P, Dunning A, Milne R, Bojesen S, Swerdlow A, Andrulis I, Brenner H, ..., Dieffenbach AK, Arndt V, Stegmaier C, ..., Hall P, Easton D, Chang-Claude J.
Indentification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions.
Genetic Epidemiology 2014; 38:84-93.

Bock JO, Matschinger H, Brenner H, Wild B, Haefeli WE, Quinzler R, Saum KU, Heider D, König HH.
Inequalities in out-of-pocket payments for health care services among elderly Germans - results of a population-based cross-sectional study.
International Journal for Equity in Health 2014; 13:3.

Pulte DP, Jansen L, Gondos A, Katalinic A, Barnes B, Ressing M, Holleczek B, Eberle A, Brenner H and the GEKID Cancer Survival Working Group.
Survival of adults with acute lymphoblastic leukemia in Germany and the United States.
PLoS One 2014; 9:e85554.

Zhang Y, Yang R, Burwinkel B, Breitling LP, Brenner H.
F2RL3 methylation as a biomarker  of current and lifetime smoking exposures.
Environmental Health Perspectives 2014; 122:131-137.

Florath I, Butterbach K, Müller H, Bewerunge-Hudler M, Brenner H.
Cross-sectional and longitudinal changes in DNA methylation with age: An epigenome-wide analysis revealing over 60 novel age-associated CpG sites.
Human Molecular Genetics 2014; 23:1186-1201.

Agarwal D, Pineda S, Michailidou K, Herranz J, Pita G, Moreno LT, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Zamora P, Benítz J, Milne RL.
FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium.
British Journal of Cancer 2014; 110:1088-1100.

Brenner H, Hoffmeister M.
Darmkrebsfrüherkennung.
Bundesgesundheitsblatt 2014; 57:302-306.

Brenner H, Chang-Claude J, Jansen L, Knebel P, Stock C, Hoffmeister M.
Reduced risk of colorectal cancer up to 10 years after screening surveillance or diagnostic colonoscopy.
Gastroenterology 2014; 146:709-717.

Genuneit J, Braig S, Brandt S, Wabitsch M, Florath I, Brenner H, Rothenbacher D.
Infant atopic eczema and subsequent attention-deficit/hyperactivity disorder - a prospective birth cohort study.
Pediatric Allergy and Immunology 2014; 25:51-56.

Saunders EJ, Dadaev T, Leongamornlert DA, Jugurnauth-Littel S, Tymrakiewicz M, Wiklund F, ..., Brenner H, ..., COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative, The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology, The UK ProtecT Study Collaborators, The PRACTICAL Consortium, Easton DF, Muir K, Eeles RA, Kote-Jarai Z.
Fine-mapping the HOXB region detects common variants tagging a rare coding allele - evidence for synthetic association in prostate cancer.
PLoS Genetics 2014; 10:e1004129.

Heider D, Matschinger H, Müller H, Saum KU, Quinzler R, Haefeli WE, Wild B, Lehnert T, Brenner H, König HH.
Health care costs in the elderly in Germany: an analysis applying Andersen's behavioral model of health care utilization.
Health Services Research 2014; 14:71.

Pennells L, Kaptoge S, White IR, Thompson SG, Wood AM; Emerging Risk Factors Collaboration*.
Assessing risk prediction models using individual participant data from multiple studies.
American Journal of Epidemiology 2014; 179:621-632.
* Authors on behalf of the ESTHER study: Brenner H, Schöttker B, Müller H, Rothenbacher D.

Gatta G, Botta L, Rossi S, Aareleid T, Bielska-Lasota M, Clavel J, Dimitrova N, Jakab Z, Kaatsch P, Lacour B, Mallone S, Marcos-Gragera R, Minicozzi P, Sánchez-Pérez MJ, Sant M, Santaquilani M, Stiller C, Tavilla A, Trama A, Visser O, Peris-Bonet R, EUROCARE Working Group*.
Childhood cancer survival in Europe 1999-2007: results of EUROCARE-5 -- a population-based study.
Lancet Oncology 2014; 15:35-47.
*Members from Germany: Meyer M, Stabenow R, Eberle A, Luttmann S, Brenner H, Nennecke A, Engel J, Schubert-Fritschle G, Kieschke J, Batzler W, Holleczek B, Katalinic A.

Tao S, Hoffmeister M, Brenner H.
Development and validation of a scoring system to identify individuals at high risk for advanced colorectal neoplasms who should undergo colonoscopy screening.
Clinical Gastroenterology and Hepatology 2014; 12:478-485.

Nagelhout GE, van den Putte B, Allwright S, Mons U, McNeill A, Guignard R, Beck F, Siahpush M, Joossens L, Fong GF, de Vries H, Willemsen MC.
Socioeconomic and country variations in cross-border cigarette purchasing as tobacco tax avoidance strategy. Findings from the ITC Europe Surveys.
Tobacco Control 2014; 23:i30-i38.

Rennen E, Nagelhout GE, von den Putte B, Janssen E, Mons U, Guignard R, Beck F, de Vries H, Thrasher JF, Willemsen MC.
Associations between tobacco control policy awareness, social acceptability of smoking and smoking cessation. Findings from the International Tobacco Control (ITC) Europe Surveys.
Health Education Research 2014; 29:72-82.

Leoncini E, Ricciardi W, Cadoni G, Arzani D, Petrelli L, Paludetti G, Brennan P, Luce D, Stucker I, matsuo K, Talamini R, La Vecchia C, Olshan AF, Winn DM, Herreror R, Franceschi S, Castellsague X, Muscat J, Morgenstern H, Zhang ZF, Levi F, Dal Maso L, Kelsey K, McClean M, Vaughan TL, Lazarus P, Purdue MP, Hayes RB, Chen C, Schwartz SM, Shangina O, Koifman S, Ahrens W, Matos E, Lagiou P, Lissowska J, Szeszenia-Dabrowska N, Fernandez L, Menezes A, Agudo A, Daudt AW, Richiardi L, Kjaerheim K, Mates D, Betka J, Yu GP, Schantz S, Simonato L, Brenner H, Conway DI, Macfarlane TV, Thomson P, Fabianova E, Znaor A, rudnai P, Healy C, Boffetta P, Chuang SC, Lee YC, Hashibe M, Boccia S.
Adult height and head and neck cancer: a pooled analysis within the INHANCE Consortium.
European Journal of Epidemiology 2014; 29:35-48.

Müezzinler A, Zaineddin AK, Brenner H.
Body mass index and leukocyte telomere length in adults: a systematic review and meta-analysis.
Obesity Reviews 2014; 15:192-201.

Pulte D, Jansen L, Gondos A, Emrich K, Holleczek B, Katalinic A, Brenner H, and the GEKID Cancer Survival Working Group.
Improved population level survival in younger Hodgkin lymphoma patients in Germany in the early 21st century.
British Journal of Haematology 2014;164:851-857.

Brenner H, Hoffmeister M, Birkner B, Stock C.
Diagnostic performance of guaiac based fecal occult blood test in routine screening: state-wide analysis from Bavaria, Germany.
American Journal of Gastroenterology 2014; 109:427-435.

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP,  Zamora MP, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Benitez J, Malats N, Easton DF.
A large-scale assessment of two-way SNP interactions in breast cancer suceptibility using 46.450 cases and 42.461 controls from the Breast Cancer Association Consortium.
Human Molecular Genetics 2014; 23:1934-1946.

Florath I, Kohler M, Weck MN, Brandt S, Rothenbacher D, Schöttker B, Moß A, Gottmann P, Wabitsch M, Brenner H.
Association of pre- and postnatal parental smoking with offspring body mass index: 8-year follow-up of a birth cohort.
Pedatric Obesity 2014; 9:121-134.

Chen H, Werner S, Tao S, Zörnig I, Brenner H.
Blood antibodies against tumor-associated antigens as biomarkers in early detection of colorectal cancer.
Cancer Letters 2014; 346:178-187.

Hoffmeister M, Jansen L, Stock C, Chang-Claude J, Brenner H.
Smoking, lower gastrointestinal endoscopy, and risk for colorectal cancer.
Cancer Epidemiology, Biomarkers & Prevention 2014; 23:525-533.

The Emerging Risk Factor Collaboration*
Glycated hemoglobin measurement and prediction of cardiovascular disease.
JAMA 2014; 311:1225-1233
*Author on behalf of the ESTHER study: Brenner H.

Brenner H, Hoffmeister M, Birkner B, Stock C.
Men with negative results of guaiac based fecal occult blood test have higher prevalences of colorectal neoplasms than women with positive results.
International Journal of Cancer 2014; 134:2927-2934.

Koch L, Bertram H, Eberle A, Holleczek B, Schmid-Höpfner S, Waldmann A, Zeissig S, Brenner H, Arndt V.
Fear of recurrence in long-term breast cancer survivors - still an issue. Results on prevalence, determinants, and the association with quality of life and depression from the Cancer Survivorship - a multi-regional population-based study.
Psycho-Oncology 2014; 23:547-554.

Brenner H, Stock C, Hoffmeister M.
Effect of  screening sigmoidoscopy and screening colonoscopy on colorectal cancer incidence and mortality: systematic review and meta-analysis of randomised controlled trials and observational studies.
British Medical Journal 2014;348:g2467 doi: 10.1136/bmj.g2467.

Maalmi H, Ordonez-Mena JM, Schöttker B, Brenner H.
Serum 25-hydroxyvitamin D levels and survival in colorectal and breast cancer patients: Systematic review and meta-analysis of prospective cohort studies.
European Journal of Cancer 2014; 50:1510-1521.

Jansen L, Eberle A, Emrich K, Gondos A, Holleczek B, Kajüter H, Maier W, Nennecke A, Pritzkuleit R, Brenner H for the GEKID Cancer Survival Group.
Socio-economic deprivation and cancer survival in Germany.
International Journal of Cancer 2014; 134;2951-2960.

Jansen L, Hoffmeister M, Arndt V, Chang-Claude J, Brenner H.
Stage-speicific associations between beta blocker use and prognosis after colorectal cancer.
Cancer 2014; 120:1178-1186.

Brenner H, Kloor M, Pox C.
Colorectal cancer.
Lancet 2014; 383:1490-1502.

Figueiredo JC, Hsu L, Hutter CM, Campbell PT, Baron JA, Berndt SI, Shuo J, Casey G, Fortini B, Chan AT, Cotterchio M, Lemire M, Gallinger S, Harrison TA, Le Marchand L, Newcomb PA, Slattery ML, Caan BJ, Carlson CS, Zanke BW, Rosse SA, Brenner H, Giovannucci EL, Wu K, Chang-Claude J, Chanock SJ, Curtis KR, Duggan D, Gong J, Haile RW, Hayes RB, Hoffmeister M, Hopper JL, Jenkins MA, Kolonel LN, Qu C, Rudolph A, Schoen RE, Schumacher FR, Seminara D, Stelling DL, Thibodeau SN, Thornquist M, Warnick GS, Henderson BE, Ulrich CM, Gauderman WJ, Potter JD, White E, and Peters U on behalf of CCFR and GECCO.
Genome-wide diet-gene interaction analyses for risk of colorectal cancer.
PLoS Genetics 2014; 10:e1004228.

Sawyer E, Roylance R, Petridis C, Brook MN, Sowinski S, Papouli E, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Schmidt MK, Tomlinson I, Garcia-Closas M.
Genetic predisposition to in situ and invasive lobular carcinoma of the breast.
PLoS Genetics 2014; 10e1004285.

Kolar DR, Bürger A, Hammerle F, Jenetzky E.
Aversive tension of adolescents with anorexia nervosa in daily course: a case-controlled and smartphone-based ambulatory monitoring trial.
BMJ Open 2014; 4:e004703.

Cheng I, Kocarnik JM, Dumitrescu L, Lindor N, Chang-Claude J, Avery C, Caberto C, Love SA, Slattery ML, Chan AT, Baron J, Hindorff LA, Park SL, Schumacher FR, Hoffmeister M, Kraft P, Butler A, Junkins HA, Duggan D, Hou L, Carlson CS, Monroe K, Lin Y, Carty CL, Mann S, Ma J, Giovannucci E, Fuchs C, Newcomb P, Jenkins M, Hopper J, Haile R, Conti DV, Campbell PT, Potter J, Caan B, Schoen RE, Hayes R, Chanock S, Berndt S, Kury S, Bezieau S, Ambite JL, Kumaraguruparan G, Richardson D, Goodloe RJ, Dikls HH, Baker P, Zanke B, Lemire M, Gallinger S, Hsu L, Jiao S, Harrison T, Seminara D, Haiman CA, Kooperberg C, Wilkens LR, Hutter C, White E, Bush WS, Heiss G, Hudson TJ, Crawford DC, Brenner H, Casey G, Le Marchand L, Peters U.
Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO, and CCFR Consortia.
Gut 2014; 63:800-807.

Pulte D, Redaniel MT, Brenner H, Jansen L, Jeffreys M.
Recent improvement in survival of patients with multiple myeloma: variation by ethnicity.
Leukemia and Lymphoma 2014; 55:1083-1089.

Brenner H, Hoffmeister M, Stock C.
Neue Tests zur Darmkrebsfrüherkennung. Qualitätssicherung in der Routine ist notwendig und gut realisierbar.
Deutsches Ärzteblatt 2014; 19: 842-843.

Nennecke A, Geiss K, Hentschel S, Vettorazzi E, Jansen L, Eberle A, Holleczek B, Gondos A, Brenner H, and the GEKID Cancer Survival Working Group.
Survival of cancer patients in urban and rural areas of Germany - a comparison.
Cancer Epidemiology 2014; 38: 259-265.

Schöttker B, Saum KU, Perna L, Ordonez-Mena JM, Holleczek B, Brenner H.
Is vitamin D deficiency a cause of increased morbidity and mortality at older age or simply an indicator of poor health?
European Journal of Epidemiology 2014; 29:199-210.

Saum KU, Dieffenbach AK, Müller H, Holleczek B, Hauer K, Brenner H.
Frailty prevalence and 10-year survival in community-dwelling older adults: results from the ESTHER cohort study.
European Journal of Epidemiology 2014; 29: 171-179.

Zhang B, Jia WH, Matsuda K, ..., Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO)*, ..., Shu XO, Zeng YX, Zheng W.
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
Nature Genetics 2014; 46: 533.542.
*Authors on behalf of the DACHS study: Brenner H, Chang-Claude J, Hoffmeister M.

Sainz J, Frank B, Da Silva Filho MI, Hoffmeister M, Rudolpf A, Butterbach K, Chang-Claude J, Brenner H, Hemminki K, Försti A.
GWAS-identified common variants for obesity are not associated with the risk of developing colorectal cancer.
Cancer Epidemiology, Biomarkers & Prevention 2014; 23:1125-1128.

Mons U, Hahmann H, Brenner H.
A reverse J-shaped association of leisure time physical activity with prognosis in patients with stable coronary heart disease: evidence from a large cohort with repeated measurements.
Heart 2014; 100:1043-1049.

Jiao S, Peters U, Berndt S, Brenner H, Butterbach K, Caan BJ, Carlson CS, Chan AT, Chang-Claude J, Chanock S, Curtis KR, Duggan D, Gong J, Harrison TA, Hayes RB, Henderson BE, Hoffmeister M, Kolonel LN, Le marchand L, Potter JD, Prentice RK, Rudolph A, Schoen RE, Seminara D, Slattery L, White E, Hsu L.
Estimate the heritability of colorectal cancer.
Human Molecular Genetics 2014; 23:3898-3905.

Schöttker B, Jorde R, Peasey A, Thorand B, Jansen EHJM, de Groot I, Streppel M, Gardiner J, Ordonez-Mena JM, Perna L, Wilsgaard T, Rathmann W, Feskens E, Kampman E, Siganos G, Njølstad I, Mathiesen EB, Kubinová R, Pajak A, Topor-Madry R, Tamosiunas A, Hughes M, Kee F, Bobak M, Trichopoulou A, Boffetta P, Brenner H, on behalf of the Consortium on Health and Ageing: Network of cohorts in Europe and the United States (CHANCES).
Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States.
British Medical Journal 2014; 348:g3656.

Perna L, Mons U, Kliegel M, Brenner H.
Serum 25-hydroxyvitamin D and cognitive decline: a longitudinal study among non-demented older adults.
Dementia and Geriatric Cognitive Disorders 2014; 38:254-263.

Wijers CH, de Blaauw I, Zwink N, Draaken M, van der Zanden LF, Brunner HG, Brooks A, Hofstra RM, Sloots CE, Broens PM, Wijnen MH, Ludwig M, Jenetzky E, Reutter H, Marcelis CL, Roeleveld N, van Rooij IA.
No major role for periconceptional folic acid use and its interaction with the MTHFR C677T polymorphism in the etiology of congenital anorectal malformations.
Birth Defects Research (Part A): Clinical Molecular Teratology 2014; 100:483-492.

Freigofas J, Haefeli WE, Schöttker B, Brenner H, Quinzler R.
Indirect evidence for proton pump inhibitor failure in patients taking them independent of meals.
Pharmacoepidemiology and Drug Safety 2014; 23:768-772.

Brenner H, Werner S, Chen H.
Re: Multitarget stool DNA testing for colorectal-cancer screening.
New England Journal of Medicine 2014; 371:184-188.

Gerola S, Nittka S, Kähler G, Tao S, Brenner H, Binelle G, Eils R, Brors B, Neumaier M.
Genetic variants in apoptosis-related genes associated with colorectal hyperplasia.
Genes, Chromosomes & Cancer 2014; 53:769-778.

German National Cohort (GNC) Consortium*.
The German National Cohort: aims, study design and organiziation.
European Journal of Epidemiology 2014; 29:371-382.
* Authors from the German Cancer Research Center: Brenner H, Greiser KH, Kaaks R.

Zhang Y, Yang R, Burwinkel B, Breitling LP, Holleczek B, Schöttker B, Brenner H.
F2RL3 methylation in blood DNA is a strong predictor of mortality.
International Journal of Epidemiology 2014; 43:1215-1225.

Walter V, Jansen L, Hoffmeister M, Brenner H.
Smoking and survival of colorectal cancer patients - Systematic review and meta-analysis.
Annals of Oncology 2014; 25:1517-1525.

Lukczynska A, Logan C, Nieters A, Elgizouli M, Florath I, Schöttker B, Brenner H, Rothenbacher D.
Cord blood 25 (OH) D levels and the subsequent risk of lower respiratory tract infections in early childhood: the Ulm Birth Cohort.
European Journal of Epidemiology 2014; 29:585-594.

Coresh J, Chowdhury T, Matsushita K, Sang Y, Ballew SH, Appel LJ, Arima H, Chadban SJ, Cirillo M, Djurdjev O, Green JA, Heine GH, Inker LA, Irie F, Ishani A, Ix JH, Kovesdy CP, Marks A, Ohkubo T, Shalev V, Shankar A, Wen CP, de Jong PE, Iseki K, Stengel B, Gansevoort RT, Levey AS; for the CKD Prognosis Consortium*.
Decline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality.
Journal of the American Medical Association 2014; 311:2518-2531
*Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Müller H, Schöttker B.

Sant M, Minicozzi P, Mounier M, Anderson L, Brenner H, Holleczek B, Marcos-Gragera R, Maynadié M, Monnereau A, Osca-Gelis G, Visser O, De Angelis R, and the EUROCARE-5 Working Group.
Survival for haematological malignancies in Europe 1997-2008 by region and age: results of a EUROCARE-5 population-based study.
The Lancet Oncology 2014; 15:931-942.

Wang H, Burnett T, Kono S, ..., GECCO Consortium members*, ..., CCFR Consortium members, ..., CORECT Consortium members, Tsugane S, Stram DO, Le Marchand L.
Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VT/1A.
Nature Communications 2014; 5:4613.
*GECCO Consortium members from DKFZ: Brenner H, Chang-Claude J, Hoffmeister M.

Brandt S, Moß A, Lennerz B, Koenig W, Weyermann M, Rothenbacher D, Brenner H, Waitsch M.
Plasma insulin levels in childhood are related to maternal factors - Results of the Ulm Birth Cohort Study.
Pediatric Diabetes 2014; 15:453-463.

Brenner H, Altenhofen L, Stock C, Hoffmeister M.
Incidence of colorectal adenomas: Birth cohort analysis among 4.3 million participants of screening colooscopy.
Cancer Epidemiology, Biomarkers & Prevention 2014; 23: 1920-1927.

Hirsch O, Kluckner VJ, Brandt S, Moss A, Weck M, Florath I, Wabitsch M, Hebebrand J, Schimmelmann BG, Christiansen H.
Restrained and external-emotional eating patterns in young overweight childrend - results of the ulm birth cohort study.
PLoS One 2014; 9:e105303.

Ordonez-Mena JM, Brenner H.
Vitamin D and cancer: an overview on epidemiological studies.
Advances in Experimental Medicine and Biology 2014; 810:17-32.

Wild B, Eckl A, Herzog W, Niehoff D, Lechner S, Maatouk I, Schellberg D, Brenner H, Müller H, Löwe B.
Assessing generalized anxiety disorder in elderly people by use of the GAD-7 and GAD-2 scales - results of a validation study.
American Journal of Geriatric Psychiatry 2014; 22:1029-1038.

Dihlmann S, Tao S, Echterdiek F, Herpel E, Jansen L, Chang-Claude J, Brenner H, Hoffmeister M, Kloor M.
Lack of Absent in Melanoma 2 (AIM2) expression in tumor cells is closely associated with poor survival in colorectal cancer patients.
International Journal of Cancer 2014; 135:2387-2396.

Florath I, Brandt S, Weck M, Moss A, Gottmann P, Rothenbacher D, Wabitsch M, Brenner H.
Evidence of inappropriate cardiovascular risk assessment in middle-age women based on recommended cut-points for waist circumference.
Nutrition, Metabolism & Cardiovascular Diseases 2014; 24:1112-1119.

Vimaleswaran KS, Cavadino A, Berry DJ, ..., Dieffenbach AK, ..., Schöttker B, Saum KU, ..., Brenner H, ..., Whittaker JC, Järvelin M-R, Hyppönen E.
A causal association between vitamin D status and hypertension: a Mendelian randomization study in up to 146,581 individuals.
Lancet Diabetes & Endocrinology 2014; 2:719-729.

Kantor ED, Hutter CM, Minnier J, Berndt SI, Brenner H, Caan BJ, Campbell PT, Carlson CS, Casey G, Chan AT, Chang-Claude J, Chanock SJ, Cotterchio M, Du M, Duggan D, Fuchs CS, Giovannucci EL, Gong J, Harrison TA, Hayes RB Henderson BE, Hoffmeister M, Hopper JL, Jenkins MA, Jiao S, Kolonel LN, Le Marchand L, Lemire M, Ma J, Newcomb PA, Ochs-Balcom HM, Pflugeisen BM, Potter JD, Rudolph A, Schoen RE, Seminara D, Slattery ML, Stelling DL, Thomas F, Thornquist M, Ulrich CM, Warnick GS, Zanke BW, Peters U, Hsu L, White E.
Gene-environment interaction involving recently identified colorectal cancer susceptibility loci.
Cancer Epidemiology Biomarkers & Prevention 2014; 23:1824-1833.

Menvielle G, Truong T, Jellouli F, Stücker I, Brenner H, Field JK, Hosgood HD, Hung RJ, Lan Q, Landi MT, Lazarus P, McLaughlin J, Morgenstern H, Muscat JE, Ruano-Ravina A, Schwartz AG, Seow A, Spitz M, Tardon A, Zhang Z-F, Luce D.
Education and lung cancer among never smokers.
Epidemiology 2014; 25:934-935.

Wild B, Heider D, Maatouk I, Slaets J, König HH, Niehoff D, Saum KU, Brenner H, Sönner W, Herzog W.
Significance and costs of complex bio-psycho-social health care needs in elderly people - results of a population-based study.
Psychosomatic Medicine 2014; 76:497-502.

Krilaviciute A, Smailyte G, Brenner H, Gondos A.
Cancer survival in Lithuania after the restoration of independence: rapid improvements, but persisting major gaps.
Acta Oncologica 2014; 53:1238-1244.

Saum KU, Dieffenbach AK, Müezzinler A, Müller H, Stegmaier C, Butterbach K, Canzian F, Stammer H, Boukamp P, Hauer K, Brenner H.
Frailty and telomere length: Cross sectional analysis in 3537 older adults from the ESTHER cohort.
Experimental Gerontology 2014; 58:250-258.

Al Olama AA, Kote-Jarai Z, Berndt SI, ..., Brenner H, ..., The Breast and Prostate Cancer Cohort Consortium (BPC3), The PRACTICAL Consortium, The COGS Consortium, The GAME-ON/ELLIPSE Consortium, ..., Easton DF, Eeles R, Haiman CA.
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.
Nature Genetics 2014; 46:1103-1109.

Reutter H, Draaken M, Pennimpede T, Wittler L, Brockschmidt FF, Ebert AK, Bartels E, Rösch W, Boemers TM, Hirsch K, Schmiedeke E, Meesters C, Becker T, Stein R, Utsch B, Mangold E, Nordenskjöld A, Barker G, Kockum CC, Zwink N, Holmdahl G, Läckgren G, Jenetzky E, Feitz WF, marcelis C, Wijers CH, van Rooij IA, Gearhart JP, Herrmann BG, Ludwig M, Boyadjiev SA, Nöthen MM, Mattheisen M.
Genome-wide association  study and mouse expression data identify a highly conserved 32kb intergenic region between WNT3 and WNT9b as possible susceptibility locus for isolated classic exstrophy of the bladder.
Human Molecular Genetics 2014; 23:5536-5544.

Perry JR, Day F, Elks CE, Sulem P, ..., Brenner H, ..., Dieffenbach AK, ..., Stefansson K, Murabito JM, Ong KK.
Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche.
Nature 2014; 514:92-97.

Ghoussaini M, Edwards SL, Michailidou K, ..., Brenner H, Dieffenbach AK, Arndt V, Staegmaier C, ..., French JD, Easton DF, Dunning AM.
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.
Nature Communications 2014; 4:4999.

Holleczek B, Brenner H.
Provision of breast cancer care and survival in Germany - results from a population-based high resolution study from Saarland.
BMC Cancer 2014; 14:757.

Breitling LP, Olsen H, Müller H, Schöttker B, Kliegel M, Brenner H.
Self- or physician-reported diabetes, glycemia markers, and cognitive functioning in older adults in Germany.
American Journal of Geriatric Psychiatry 2014; 11:1105-1115.

Purrington KS, Slettedahl S, Bolla MK, ..., Brenner H, ..., Dieffenbach AK, Stegmaier C, Arndt V, ..., Slager S, Vachon CM, Couch FJ.
Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.
Human Molecular Genetics 2014; 23:6034-6046.

Milne RL, Burwinkel B, Michailidou K, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Dunning AM, Chenevix-Trench G, Easton DF.
Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium.
Human Molecular Genetics 2014; 23:6096-6111.

Karakas M, Jaensch A, Breitling LP, Brenner H, Koenig W, Rothenbacher D.
Prognostic value of mid-regional pro A-type naturetic peptide and N-terminal pro B-type natriuretic peptide in patients with stable coronary heart disease followed over 8 years.
Clinical Chemistry 2014; 60:1441-1449.

Khan S, Greco D, Michailidou K, ... Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Aittomäki K, Easton DF, Nevanlinna H.
MicroRNA related polymorphisms and breast cancer risk.
PLoS One 2014; 9:e109973.

Rudolph A, Hong S, Försti A, Hoffmeister M, Sainz J, Jansen L, Hemminki K, Brenner H, Chang-Claude J.
Repeat polymorphisms in ESR2 and AR and colorectal cancer risk and prognosis: results from a German population-based case-control study.
BMC Cancer 2014; 14:817.

Wen CP, Matsushita K, Coresh J, Iseki K, Islam M, Katz R, McClellan W, Peralta CA, Wang HY, de Zeeuw D, Astor BC, Gansevoort RT, Levey AS, Levin A, and for the Chronic Kidney Disease Prognosis Consortium*. Relative risks of chronic kidney disease for mortality and end-stage renal disease across races are similar.
Kidney International 2014; 86:819-827.
*Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Müller H, Schöttker B..

Du M, Zhang X, Hoffmeister M, Schoen RE, Baron JA, Berndt SI, Brenner H, Carlson CS, Casey G, Chan AT, Curtis KR, Duggan D, Gauderman WJ, Giovannucci EL, Gong J, Harrison TA, Hayes RB, Henderson BE, Hopper L, Hsu L, Hudson TJ, Hutter CM, Jenkins MA, Jiao S, Kocarnik JM, Kolonel LN, Le Marchand L, Lin Y, Newcomb PA, Rudolph A, Seminara D, Thornquist MD, Ulrich CM, White E, Wu K, Zanke BW, Campbell PT, Slattery ML, Peters U, Chang-Claude J, Potter JD.
No evidence of gene-calcium interactions from genome-wide analysis of colorectal cancer risk.
Cancer Epidemiology, Biomarkers and Prevention 2014; 23:2971-2976.

Ristau J, Staffa J, Schrotz-King P, Gigic B, Makar KW, Hoffmeister M, Brenner H, Ulrich A, Schneider M, Ulrich CM, Habermann N.
Suitability of circulating miRNAs as potential prognostic markers in colorectal cancer.
Cancer Epidemiology, Biomarkers & Prevention 2014; 23:2632-2637.

von Winterfeld M, Hoffmeister M, Ingold-Heppner B, Jansen L, Tao S, Herpel E, Schirmacher P, Dietel M, Chang-Claude J, Autschbach F, Brenner H, Bläker H.
Frequency of therapy-relevant staging shifts in colorectal cancer through the introduction of pN1c in the 7th TNM edition.
European Journal of Cancer 2014; 50:2958-2965.

Saum KU, Mons U, Perna L, Holleczek B, Stegmaier C, Brenner H.
Die ESTHER-Studie: Stand der 14-Jahres-Nachbefragung und ausgewählte aktuelle Erkenntnisse zu Risikofaktoren für kognitive Einschränkungen im Alter.
Saarländisches Ärzteblatt 2014; 12:12-14.

Boffetta P, Bobak M, Börsch-Supan A, Brenner H, Eriksson S, Grodstein F, Jansen E, Jenab M, Juerges H, Kampman E, Kee F, Kuulasmaa K, Park Y, Tjonneland A, van Duijn C, Wilsgaards T, Wolk A, Trichopoulos D, Bamia C, Trichopoulou A.
The Consortium on Health and Ageing: Network of Cohorts in Europe and the United States (CHANCES) project: design, population and data harmonization of a large-scale, international study.
European Journal of Epidemiology 2014; 29:929-936.

O'Doherty MG, Jørgensen T, Borglykke A, Brenner H, Schöttker B, Wilsgaard T, Siganos G, Kavousi M, Hughes M, Müezzinler A, Holleczek B, Franco OH, Hofman A, Goffetta P, Trichopoulou A, Kee F, on behalf of the CHANCES consortium.
Repeated measures of body mass and C-reactive protein in relation to all-cause mortality and cardiovascular disease: results from the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES).
European Journal of Epidemiology 2014; 29:887-897.

Stenzinger A, Pfarr N, Endris V, Penzel R, Jansen L, Wolf T, Herpel E, Warth A, Klauschen F, Roth W, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M, Weichert W.
Mutations in POLE as key molecular alteration of the novel ultramutator phenotype do not define a clinically distinct entity of colorectal cancer.
Cancer Medicine 2014: 3:1527-1538.

Zeidler C, Woelfle J, Draaken M, Mughai SS, Große G, Hilger AC, Dworschak GC, Boemers TM, Jenetzky E, Zwink N, Lacher M, Schmidt D, Schmiedeke E, Grasshoff-Derr S, Märzheuser S, Holland-Cunz S, Schäfer M, Bartels E, Keppler K, Palta M, Leonhardt J, Kujath C, Rißmann A, Nöthen MM, Reutter H, Ludwig M.
Heterozygous FGF8 mutations in patients presenting cryptorchidism and multiple VATER/VACTERL features without limb anormalies.
Birth Defects Research Part A: Clinical and Molecular Teratology 2014; 100:750-759.

Johnson N, Dudbridge F, Orr N, ..., Brenner H, Müller H, Arndt V, Dieffenbach AK, ..., Peto J, dos Santos Silva I, Fletscher O.
Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study.
Breast Cancer Research 2014; 16:R51.

Rüter G, Mons U, Brenner H.
Neue  Optimierungswege der allgemeinärztlichen Betreuung bei Typ-2-Diabetes. Ergebnisse der DIANA-Studie.
Der Diabetologe 2014; 10:207-216.

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