Groups and Projects

The Molecular Diagnostics Group is involved in the establishment of diagnostic innovations and interpretation of results, but also drives the identification and characterization of novel genetic aberrations in pediatric gliomas of different grades.

The Preclinical Research Group conducts drug screens in childhood brain tumor models as well as preclinical experiments with pre-selected promising drugs, but at the same time aims at understanding the molecular make-up of embryonal brain tumors including atypical teratoid-rhabdoid tumors (AT/RT), embryonal tumors with multilayered rosettes (ETMR), and supratentorial primitive neuroectodermal tumors (stPNET) as well as ependymomas.

The In Vivo Group is a joint group between the Division of Pediatric Neurooncology and the Division of Molecular Genetics. This group focuses in generating faithful brain tumor mouse models that are necessary to test new treatment options before they can ultimately be given to patients.

The group Computational Oncoepigenomics is responsible for the establishment and application of bioinformatics methods to handle and analyze large-scale (epi)genomics data.

More information about the individual groups can be found at the webpage of the Pediatric Neurooncology Center Heidelberg (see also the individual links above).

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