Publications

2016

  • Bauer T, Trump S, Ishaque N, Thurmann L, Gu L, Bauer M, Bieg M, Gu Z, Weichenhan D, Mallm JP, Roder S, Herberth G, Takada E, Mucke O, Winter M, Junge KM, Grutzmann K, Rolle-Kampczyk U, Wang Q, Lawerenz C, Borte M, Polte T, Schlesner M, Schanne M, Wiemann S, Georg C, Stunnenberg HG, Plass C, Rippe K, Mizuguchi J, Herrmann C and Eils R: Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children. Mol Syst Biol 2016, 12 (3):861. doi: 10.15252/msb.20156520. Pubmed: http://http://www.ncbi.nlm.nih.gov/pubmed/27013061
  • Haller F, Knopf J, Ackermann A, Bieg M, Kleinheinz K, Schlesner M, Moskalev EA, Will R, Satir AA, Abdelmagid IE, Giedl J, Carbon R, Rompel O, Hartmann A, Wiemann S, Metzler M and Agaimy A: Paediatric and adult soft tissue sarcomas with NTRK1 gene fusions: a subset of spindle cell sarcomas unified by a prominent myopericytic/haemangiopericytic pattern. J Pathol 2016, 238(5):710-10. doi: 10.1002/path.4701. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26863915
  • Marzi MJ, Ghini F, Cerruti B, de Pretis S, Bonetti P, Giacomelli C, Gorski MM, Kress T, Pelizzola M, Muller H, Amati B and Nicassio F: Degradation dynamics of microRNAs revealed by a novel pulse-chase approach. Genome Res 2016, 26 (4):554-65. doi: 10.1101/gr.198788.115. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26821571
  • Rafiullah R, Aslamkhan M, Paramasivam N, Thiel C, Mustafa G, Wiemann S, Schlesner M, Wade RC, Rappold GA and Berkel S: Homozygous missense mutation in the LMAN2L gene segregates with intellectual disability in a large consanguineous Pakistani family. J Med Genet 2016, 53 (2):138-44. doi: 10.1136/jmedgenet-2015-103179. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26566883
  • Salem O, Erdem N, Jung J, Munstermann E, Worner A, Wilhelm H, Wiemann S and Korner C: The highly expressed 5'isomiR of hsa-miR-140-3p contributes to the tumor-suppressive effects of miR-140 by reducing breast cancer proliferation and migration. BMC Genomics 2016, 17:566. doi: 10.1186/s12864-016-2869-x. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/27502506
  • Sas-Chen A, Aure MR, Leibovich L, Carvalho S, Enuka Y, Korner C, Polycarpou-Schwarz M, Lavi S, Nevo N, Kuznetsov Y, Yuan J, Azuaje F, Oslo Breast Cancer Research Consortium SauerTorillGeislerJurgenHofvindSolveigBathenTone FAMGCKK, Ulitsky I, Diederichs S, Wiemann S, Yakhini Z, Kristensen VN, Borresen-Dale AL and Yarden Y: LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer. EMBO Mol Med 2016, 8(9);1052-64. doi: 10.15252/emmm.201606198. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/27485121
  • von der Heyde S, Sonntag J, Kramer F, Bender C, Korf U and Beissbarth T: Reconstruction of Protein Networks Using Reverse-Phase Protein Array Data. Methods Mol Biol 2016, 1362:227-46. doi: 10.1007/978-1-4939-3106-4_15. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26519181
  • Weitzenfeld P, Kossover O, Korner C, Meshel T, Wiemann S, Seliktar D, Legler DF and Ben-Baruch A: Chemokine axes in breast cancer: factors of the tumor microenvironment reshape the CCR7-driven metastatic spread of luminal-A breast tumors. J Leukoc Biol 2016, 99(6):1009-25. doi: 10.1189/jlb.3MA0815-373R. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26936935
  • Wiemann S, Pennacchio C, Hu Y, Hunter P, Harbers M, Amiet A, Bethel G, Busse M, Carninci P, Dunham I, Hao T, Harper JW, Hayashizaki Y, Heil O, Hennig S, Hotz-Wagenblatt A, Jang W, Jöcker A, Kawai J, Koenig C, Korn B, Lambert C, LeBeau A, Lu S, Maurer J, Moore T, Ohara O, Park J, Rolfs A, Salehi-Ashtiani K, Seiler C, Simmons B, van Brabant Smith A, Steel J, Wagner L, Weaver T, Wellenreuther R, Yang S, Vidal M, Gerhard DS, LaBaer J, Temple G and DE H: The ORFeome Collaboration: a genome-scale human ORF-clone resource. Nat Methods 2016, 13 (3):191-2. doi: 10.1038/nmeth.3776. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26914201
  • Winkler EC and Wiemann S: Findings made in gene panel to whole genome sequencing: data, knowledge, ethics - and consequences? Expert Rev Mol Diagn 2016. doi: 10.1080/14737159.2016.1212662. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/27409399

2015

  • Barrangou R, Birmingham A, Wiemann S, Beijersbergen RL, Hornung V, Smith A: Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference. Nucleic Acids Res 2015, 43(7):3407-3419. PMID: 25800748 Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25800748
  • Ben-Chetrit N, Chetrit D, Russell R, Korner C, Mancini M, Abdul-Hai A, Itkin T, Carvalho S, Cohen-Dvashi H, Koestler WJ, Shukla K, Lindzen M, Kedmi M, Lauriola M, Shulman Z, Barr H, Seger D, Ferraro DA, Pareja F, Gil-Henn H, Lapidot T, Alon R, Milanezi F, Symons M, Ben-Hamo R, Efroni S, Schmitt F, Wiemann S, Caldas C, Ehrlich M and Yarden Y: Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer. Sci Signal 2015, 8 (360):ra7. doi: 10.1126/scisignal.2005537. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25605973
  • Ceroni F, Simpson NH, Francks C, Baird G, Conti-Ramsden G, Clark A, Bolton PF, Hennessy ER, Donnelly P, Bentley DR, Martin H, Imgsac, Consortium SLI, Consortium WGS, Parr J, Pagnamenta AT, Maestrini E, Bacchelli E, Fisher SE and Newbury DF: Reply to Pembrey et al: 'ZNF277 microdeletions, specific language impairment and the meiotic mismatch methylation (3M) hypothesis'. Eur J Hum Genet 2015, 23 (9):1113-5. doi: 10.1038/ejhg.2014.275. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25537359
  • Chiocchetti AG, Kopp M, Waltes R, Haslinger D, Duketis E, Jarczok TA, Poustka F, Voran A, Graab U, Meyer J, Klauck SM, Fulda S and Freitag CM: Variants of the CNTNAP2 5' promoter as risk factors for autism spectrum disorders: a genetic and functional approach. Mol Psychiatry 2015, 20 (7):839-49. doi: 10.1038/mp.2014.103. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25224256
  • Cohen-Dvashi H, Ben-Chetrit N, Russell R, Carvalho S, Lauriola M, Nisani S, Mancini M, Nataraj N, Kedmi M, Roth L, Kostler W, Zeisel A, Yitzhaky A, Zylberg J, Tarcic G, Eilam R, Wigelman Y, Will R, Lavi S, Porat Z, Wiemann S, Ricardo S, Schmitt F, Caldas C and Yarden Y: Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression. EMBO Mol Med 2015, 7 (3):299-314. doi: 10.15252/emmm.201404134. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25678558
  • Frohlich H, Bahamondez G, Gotschel F and Korf U: Dynamic Bayesian Network Modeling of the Interplay between EGFR and Hedgehog Signaling. PLoS One 2015, 10 (11):e0142646. doi: 10.1371/journal.pone.0142646. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26571415
  • Haller F, Bieg M, Moskalev EA, Barthelmess S, Geddert H, Boltze C, Diessl N, Braumandl K, Brors B, Iro H, Hartmann A, Wiemann S and Agaimy A: Recurrent mutations within the amino-terminal region of beta-catenin are probable key molecular driver events in sinonasal hemangiopericytoma. Am J Pathol 2015, 185 (2):563-71. doi: 10.1016/j.ajpath.2014.10.019. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25482924
  • Haller F, Zhang JD, Moskalev EA, Braun A, Otto C, Geddert H, Riazalhosseini Y, Ward A, Balwierz A, Schaefer IM, Cameron S, Ghadimi BM, Agaimy A, Fletcher JA, Hoheisel J, Hartmann A, Werner M, Wiemann S and Sahin O: Combined DNA methylation and gene expression profiling in gastrointestinal stromal tumors reveals hypomethylation of SPP1 as an independent prognostic factor. Int J Cancer 2015, 136 (5):1013-23. doi: 10.1002/ijc.29088. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25046773
  • Kedmi M, Ben-Chetrit N, Korner C, Mancini M, Ben-Moshe NB, Lauriola M, Lavi S, Biagioni F, Carvalho S, Cohen-Dvashi H, Schmitt F, Wiemann S, Blandino G and Yarden Y: EGF induces microRNAs that target suppressors of cell migration: miR-15b targets MTSS1 in breast cancer. Sci Signal 2015, 8 (368):ra29. doi: 10.1126/scisignal.2005866. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25783158
  • Keklikoglou I, Hosaka K, Bender C, Bott A, Koerner C, Mitra D, Will R, Woerner A, Muenstermann E, Wilhelm H, Cao Y and Wiemann S: MicroRNA-206 functions as a pleiotropic modulator of cell proliferation, invasion and lymphangiogenesis in pancreatic adenocarcinoma by targeting ANXA2 and KRAS genes. Oncogene 2015, doi: 10.1038/onc.2014.408. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25500542
  • Maier R, Moser G, Chen GB, Ripke S, Cross-Disorder Working Group of the Psychiatric Genomics C, Coryell W, Potash JB, Scheftner WA, Shi J, Weissman MM, Hultman CM, Landen M, Levinson DF, Kendler KS, Smoller JW, Wray NR and Lee SH: Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. Am J Hum Genet 2015, 96 (2):283-94. doi: 10.1016/j.ajhg.2014.12.006. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25640677
  • Network and Pathway Analysis Subgroup of Psychiatric Genomics C: Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci 2015, 18 (2):199-209. doi: 10.1038/nn.3922. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25599223
  • Peckys DB, Korf U and de Jonge N: Local variations of HER2 dimerization in breast cancer cells discovered by correlative fluorescence and liquid electron microscopy. Science Advances 2015, 1 (6):doi: 10.1126/sciadv.1500165. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26601217
  • Schuol S, Schickhardt C, Wiemann S, Bartram CR, Tanner K, Eils R, Meder B, Richter D, Glimm H, von Kalle C and Winkler EC: So rare we need to hunt for them: reframing the ethical debate on incidental findings. Genome Med 2015, 7 (1):83. doi: 10.1186/s13073-015-0198-3. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26229554
  • Shukla K, Sharma AK, Ward A, Will R, Hielscher T, Balwierz A, Breunig C, Munstermann E, Konig R, Keklikoglou I and Wiemann S: MicroRNA-30c-2-3p negatively regulates NF-kappaB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer. Mol Oncol 2015, 9 (6):1106-19. doi: 10.1016/j.molonc.2015.01.008. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25732226
  • von der Heyde S, Wagner S, Czerny A, Nietert M, Ludewig F, Salinas-Riester G, Arlt D and Beissbarth T: mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer. PLoS One 2015, 10 (2):e0117818. doi: 10.1371/journal.pone.0117818. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25710561
  • Wachter A, Bernhardt S, Beissbarth T and Korf U: Analysis of Reverse Phase Protein Array Data: From Experimental Design towards Targeted Biomarker Discovery. Microarrays 2015, 4 (4):520. doi: doi:10.3390/microarrays4040520. Pubmed:
  • Wruck W, Kashofer K, Rehman S, Daskalaki A, Berg D, Gralka E, Jozefczuk J, Drews K, Pandey V, Regenbrecht C, Wierling C, Turano P, Korf U, Zatloukal K, Lehrach H, Westerhoff HV and Adjaye J: Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes. Sci Data 2015, 2 150068. doi: 10.1038/sdata.2015.68. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26646939
  • Zanni G, Kalscheuer VM, Friedrich A, Barresi S, Alfieri P, Di Capua M, Haas SA, Piccini G, Karl T, Klauck SM, Bellacchio E, Emma F, Cappa M, Bertini E and Breitenbach-Koller L: A Novel Mutation in RPL10 (Ribosomal Protein L10) Causes X-Linked Intellectual Disability, Cerebellar Hypoplasia, and Spondylo-Epiphyseal Dysplasia. Hum Mutat 2015, 36 (12):1155-8. doi: 10.1002/humu.22860. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/26290468

2014

  • Agaimy A, Barthelmess S, Geddert H, Boltze C, Moskalev E, Koch M, Wiemann S, Hartmann A and Haller F: Phenotypic And Molecular Distinctness of Sinonasal Hemangiopericytoma compared to Solitary Fibrous Tumor of the Sinonasal Tract. Histopathology 2014. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24807787
  • Akbani R, Becker KF, Carragher N, Goldstein T, de Koning L, Korf U, Liotta L, Mills GB, Nishizuka SS, Pawlak M, Petricoin EF, 3rd, Pollard HB, Serrels B and Zhu J: Realizing the Promise of Reverse Phase Protein Arrays for Clinical, Translational, and Basic Research: A Workshop Report: The RPPA (Reverse Phase Protein Array) Society. Mol Cell Proteomics 2014, 13(7):1625-43. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24777629
  • Barthelmess S, Geddert H, Boltze C, Moskalev EA, Bieg M, Sirbu H, Brors B, Wiemann S, Hartmann A, Agaimy A and Haller F: Solitary fibrous tumors/hemangiopericytomas with different variants of the NAB2-STAT6 gene fusion are characterized by specific histomorphology and distinct clinicopathological features. Am J Pathol 2014, 184(4):1209-18. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24513261
  • Breunig C, Mueller BJ, Umansky L, Wahl K, Hoffmann K, Lehner F, Manns MP, Bantel H and Falk CS: BRaf and MEK inhibitors differentially regulate cell fate and microenvironment in human hepatocellular carcinoma. Clin Cancer Res 2014, 20(9):2410-23. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24573550
  • Buxbaum JD, Bolshakova N, Brownfeld JM, Anney RJ, Bender P, Bernier R, Cook EH, Coon H, Cuccaro M, Freitag CM, Hallmayer J, Geschwind D, Klauck SM, Nurnberger JI, Oliveira G, Pinto D, Poustka F, Scherer SW, Shih A, Sutcliffe JS, Szatmari P, Vicente AM, Vieland V, Gallagher L: The Autism Simplex Collection: an international, expertly phenotyped autism sample for genetic and phenotypic analyses. Molecular autism 2014, 5:34. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25392729
  • Chiocchetti AG, Haslinger D, Boesch M, Karl T, Wiemann S, Freitag CM, Poustka F, Scheibe B, Bauer JW, Hintner H, Breitenbach M, Kellermann J, Lottspeich F, Klauck SM and Breitenbach-Koller L: Protein signatures of oxidative stress response in a patient specific cell line model for autism. Mol Autism 2014, 5(1):10. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24512814
  • Chiocchetti AG, Kopp M, Waltes R, Haslinger D, Duketis E, Jarczok TA, Poustka F, Voran A, Graab U, Meyer J, Klauck SM, Fulda S, Freitag CM: Variants of the CNTNAP2 5' promoter as risk factors for autism spectrum disorders: a genetic and functional approach. Molecular psychiatry 2014. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25224256
  • De Rubeis S, He X, Goldberg AP, Poultney CS, Samocha K, Ercument Cicek A, Kou Y, Liu L, Fromer M, Walker S, Singh T, Klei L, Kosmicki J, Fu SC, Aleksic B, Biscaldi M, Bolton PF, Brownfeld JM, Cai J, Campbell NG, Carracedo A, Chahrour MH, Chiocchetti AG, Coon H, Crawford EL, Crooks L, Curran SR, Dawson G, Duketis E, Fernandez BA, Gallagher L, Geller E, Guter SJ, Sean Hill R, Ionita-Laza I, Jimenez Gonzalez P, Kilpinen H, Klauck SM, Kolevzon A, Lee I, Lei J, Lehtimaki T, Lin CF, Ma'ayan A, Marshall CR, McInnes AL, Neale B, Owen MJ, Ozaki N, Parellada M, Parr JR, Purcell S, Puura K, Rajagopalan D, Rehnstrom K, Reichenberg A, Sabo A, Sachse M, Sanders SJ, Schafer C, Schulte-Ruther M, Skuse D, Stevens C, Szatmari P, Tammimies K, Valladares O, Voran A, Wang LS, Weiss LA, Jeremy Willsey A, Yu TW, Yuen RK, Study DDD, Homozygosity Mapping Collaborative for A, Consortium UK, Autism Sequencing C, Cook EH, Freitag CM, Gill M, Hultman CM, Lehner T, Palotie A, Schellenberg GD, Sklar P, State MW, Sutcliffe JS, Walsh CA, Scherer SW, Zwick ME, Barrett JC, Cutler DJ, Roeder K, Devlin B, Daly MJ, Buxbaum JD: Synaptic, transcriptional and chromatin genes disrupted in autism. Nature 2014, 515(7526):209-215. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25363760
  • Doberstein K, Bretz NP, Schirmer U, Fiegl H, Blaheta R, Breunig C, Muller-Holzner E, Reimer D, Zeimet AG, Altevogt P: miR-21-3p is a positive regulator of L1CAM in several human carcinomas. Cancer Lett 2014. Aug 19. pii: S0304-3835(14)00450-9. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25149066
  • Haller F, Moskalev EA, Faucz FR, Barthelmess S, Wiemann S, Bieg M, Assie G, Bertherat J, Schaefer IM, Otto C, Rattenberry E, Maher ER, Strobel P, Werner M, Carney JA, Hartmann A, Stratakis CA and Agaimy A: Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad. Endocr Relat Cancer 2014, 21(4):567-77. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24859990
  • Hulsmann HJ, Rolff J, Bender C, Jarahian M, Korf U, Herwig R, Frohlich H, Thomas M, Merk J, Fichtner I, Sultmann H, Kuner R: Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib. Lung cancer (Amsterdam, Netherlands) 2014. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25240516
  • Lauriola M, Enuka Y, Zeisel A, D'Uva G, Roth L, Sharon-Sevilla M, Lindzen M, Sharma K, Nevo N, Feldman M, Carvalho S, Cohen-Dvashi H, Kedmi M, Ben-Chetrit N, Chen A, Solmi R, Wiemann S, Schmitt F, Domany E and Yarden Y: Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment. Nat Commun 2014, 5 5073. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25278152
  • Mleczko-Sanecka K, Roche F, da Silva AR, Call D, D'Alessio F, Ragab A, Lapinski PE, Ummanni R, Korf U, Oakes C, Damm G, D'Alessandro LA, Klingmuller U, King PD, Boutros M, Hentze MW and Muckenthaler MU: Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling. Blood 2014, 123(10):1574-85. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24385536
  • Nass N, Bromme HJ, Hartig R, Korkmaz S, Sel S, Hirche F, Ward A, Simm A, Wiemann S, Lykkesfeldt AE, Roessner A and Kalinski T: Differential Response to alpha-Axoaldehydes in Tamoxifen Resistant MCF-7 Breast Cancer Cells. PLoS One 2014, 9(7):e101473. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24983248
  • Negm OH, Mannsperger HA, McDermott EM, Drewe E, Powell RJ, Todd I, Fairclough LC and Tighe PJ: A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS). Eur J Immunol 2014, 44(7):2096-110. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24668260
  • Northcott PA, Lee C, Zichner T, Stutz AM, Erkek S, Kawauchi D, Shih DJ, Hovestadt V, Zapatka M, Sturm D, Jones DT, Kool M, Remke M, Cavalli FM, Zuyderduyn S, Bader GD, VandenBerg S, Esparza LA, Ryzhova M, Wang W, Wittmann A, Stark S, Sieber L, Seker-Cin H, Linke L, Kratochwil F, Jager N, Buchhalter I, Imbusch CD, Zipprich G, Raeder B, Schmidt S, Diessl N, Wolf S, Wiemann S, Brors B, Lawerenz C, Eils J, Warnatz HJ, Risch T, Yaspo ML, Weber UD, Bartholomae CC, von Kalle C, Turanyi E, Hauser P, Sanden E, Darabi A, Siesjo P, Sterba J, Zitterbart K, Sumerauer D, van Sluis P, Versteeg R, Volckmann R, Koster J, Schuhmann MU, Ebinger M, Grimes HL, Robinson GW, Gajjar A, Mynarek M, von Hoff K, Rutkowski S, Pietsch T, Scheurlen W, Felsberg J, Reifenberger G, Kulozik AE, von Deimling A, Witt O, Eils R, Gilbertson RJ, Korshunov A, Taylor MD, Lichter P, Korbel JO, Wechsler-Reya RJ and Pfister SM: Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma. Nature 2014, 511(7510):428-34. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25043047
  • Pinto D, Delaby E, Merico D, Barbosa M, Merikangas A, Klei L, Thiruvahindrapuram B, Xu X, Ziman R, Wang Z, Vorstman JA, Thompson A, Regan R, Pilorge M, Pellecchia G, Pagnamenta AT, Oliveira B, Marshall CR, Magalhaes TR, Lowe JK, Howe JL, Griswold AJ, Gilbert J, Duketis E, Dombroski BA, De Jonge MV, Cuccaro M, Crawford EL, Correia CT, Conroy J, Conceicao IC, Chiocchetti AG, Casey JP, Cai G, Cabrol C, Bolshakova N, Bacchelli E, Anney R, Gallinger S, Cotterchio M, Casey G, Zwaigenbaum L, Wittemeyer K, Wing K, Wallace S, van Engeland H, Tryfon A, Thomson S, Soorya L, Roge B, Roberts W, Poustka F, Mouga S, Minshew N, McInnes LA, McGrew SG, Lord C, Leboyer M, Le Couteur AS, Kolevzon A, Jimenez Gonzalez P, Jacob S, Holt R, Guter S, Green J, Green A, Gillberg C, Fernandez BA, Duque F, Delorme R, Dawson G, Chaste P, Cafe C, Brennan S, Bourgeron T, Bolton PF, Bolte S, Bernier R, Baird G, Bailey AJ, Anagnostou E, Almeida J, Wijsman EM, Vieland VJ, Vicente AM, Schellenberg GD, Pericak-Vance M, Paterson AD, Parr JR, Oliveira G, Nurnberger JI, Monaco AP, Maestrini E, Klauck SM, Hakonarson H, Haines JL, Geschwind DH, Freitag CM, Folstein SE, Ennis S, Coon H, Battaglia A, Szatmari P, Sutcliffe JS, Hallmayer J, Gill M, Cook EH, Buxbaum JD, Devlin B, Gallagher L, Betancur C and Scherer SW: Convergence of genes and cellular pathways dysregulated in autism spectrum disorders. Am J Hum Genet 2014, 94(5):677-94. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24768552
  • Schirmer U, Doberstein K, Rupp AK, Bretz NP, Wuttig D, Kiefel H, Breunig C, Fiegl H, Muller-Holzner E, Zeillinger R, Schuster E, Zeimet AG, Sultmann H and Altevogt P: Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma. Oncotarget 2014, 5(2):462-72. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24497324
  • Sonntag J, Bender C, Soons Z, der Heyde Sv, König R, Wiemann S, Sinn H-P, Schneeweiss A, Beißbarth T and Korf U: Reverse phase protein array based tumor profiling identifies a biomarker signature for risk classification of hormone receptor-positive breast cancer. Translational Proteomics 2014, 2(0):52-9. URL: http://www.sciencedirect.com/science/article/pii/S2212963414000023
  • Sonntag J, Schluter K, Bernhardt S, Korf U: Subtyping of breast cancer using reverse phase protein arrays. Expert Rev Proteomics 2014, 11(6):757-770. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/25400094
  • Srivastava S, Sharma K, Kumar N and Roy P: Bradykinin regulates osteoblast differentiation by Akt/ERK/NFkappaB signalling axis. J Cell Physiol 2014, epub. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24825463
  • Ummanni R, Mannsperger HA, Sonntag J, Oswald M, Sharma AK, Konig R and Korf U: Evaluation of reverse phase protein array (RPPA)-based pathway-activation profiling in 84 non-small cell lung cancer (NSCLC) cell lines as platform for cancer proteomics and biomarker discovery. Biochim Biophys Acta 2014, 1844(5):950-9. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24361481
  • von der Heyde S, Bender C, Henjes F, Sonntag J, Korf U and Beissbarth T: Boolean ErbB network reconstructions and perturbation simulations reveal individual drug response in different breast cancer cell lines. BMC Syst Biol 2014, 8(75). Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24970389
  • von der Heyde S, Sonntag J, Kaschek D, Bender C, Bues J, Wachter A, Timmer J, Korf U, Beissbarth T: RPPanalyzer toolbox: an improved R package for analysis of reverse phase protein array data. Biotechniques 2014, 57(3):125-135. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/2520904
  • Waltes R, Duketis E, Knapp M, Anney RJ, Huguet G, Schlitt S, Jarczok TA, Sachse M, Kampfer LM, Kleinbock T, Poustka F, Bolte S, Schmotzer G, Voran A, Huy E, Meyer J, Bourgeron T, Klauck SM, Freitag CM and Chiocchetti AG: Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders. Hum Genet 2014, 133(6):781-92. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24442360
  • Ward A, Shukla K, Balwierz A, Soons Z, Konig R, Sahin O and Wiemann S: MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer. J Pathol 2014, 233(4):368-79. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24752803

2013

  • Cross-Disorder Group of the Psychiatric Genomics C, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, Andreassen OA, Anjorin A, Anney R, Anttila V, Arking DE, Asherson P, Azevedo MH, Backlund L, Badner JA, Bailey AJ, Banaschewski T, Barchas JD, Barnes MR, Barrett TB, Bass N, Battaglia A, Bauer M, Bayes M, Bellivier F, Bergen SE, Berrettini W, Betancur C, Bettecken T, Biederman J, Binder EB, Black DW, Blackwood DH, Bloss CS, Boehnke M, Boomsma DI, Breen G, Breuer R, Bruggeman R, Cormican P, Buccola NG, Buitelaar JK, Bunney WE, Buxbaum JD, Byerley WF, Byrne EM, Caesar S, Cahn W, Cantor RM, Casas M, Chakravarti A, Chambert K, Choudhury K, Cichon S, Cloninger CR, Collier DA, Cook EH, Coon H, Cormand B, Corvin A, Coryell WH, Craig DW, Craig IW, Crosbie J, Cuccaro ML, Curtis D, Czamara D, Datta S, Dawson G, Day R, De Geus EJ, Degenhardt F, Djurovic S, Donohoe GJ, Doyle AE, Duan J, Dudbridge F, Duketis E, Ebstein RP, Edenberg HJ, Elia J, Ennis S, Etain B, Fanous A, Farmer AE, Ferrier IN, Flickinger M, Fombonne E, Foroud T, Frank J, Franke B, Fraser C, Freedman R, Freimer NB, Freitag CM, Friedl M, Frisen L, Gallagher L, Gejman PV, Georgieva L, Gershon ES, Geschwind DH, Giegling I, Gill M, Gordon SD, Gordon-Smith K, Green EK, Greenwood TA, Grice DE, Gross M, Grozeva D, Guan W, Gurling H, De Haan L, Haines JL, Hakonarson H, Hallmayer J, Hamilton SP, Hamshere ML, Hansen TF, Hartmann AM, Hautzinger M, Heath AC, Henders AK, Herms S, Hickie IB, Hipolito M, Hoefels S, Holmans PA, Holsboer F, Hoogendijk WJ, Hottenga JJ, Hultman CM, Hus V, Ingason A, Ising M, Jamain S, Jones EG, Jones I, Jones L, Tzeng JY, Kahler AK, Kahn RS, Kandaswamy R, Keller MC, Kennedy JL, Kenny E, Kent L, Kim Y, Kirov GK, Klauck SM, Klei L, Knowles JA, Kohli MA, Koller DL, Konte B, Korszun A, Krabbendam L, Krasucki R, Kuntsi J, Kwan P, Landen M, Langstrom N, Lathrop M, Lawrence J, Lawson WB, Leboyer M, Ledbetter DH, Lee PH, Lencz T, Lesch KP, Levinson DF, Lewis CM, Li J, Lichtenstein P, Lieberman JA, Lin DY, Linszen DH, Liu C, Lohoff FW, Loo SK, Lord C, Lowe JK, Lucae S, MacIntyre DJ, Madden PA, Maestrini E, Magnusson PK, Mahon PB, Maier W, Malhotra AK, Mane SM, Martin CL, Martin NG, Mattheisen M, Matthews K, Mattingsdal M, McCarroll SA, McGhee KA, McGough JJ, McGrath PJ, McGuffin P, McInnis MG, McIntosh A, McKinney R, McLean AW, McMahon FJ, McMahon WM, McQuillin A, Medeiros H, Medland SE, Meier S, Melle I, Meng F, Meyer J, Middeldorp CM, Middleton L, Milanova V, Miranda A, Monaco AP, Montgomery GW, Moran JL, Moreno-De-Luca D, Morken G, Morris DW, Morrow EM, Moskvina V, Muglia P, Muhleisen TW, Muir WJ, Muller-Myhsok B, Murtha M, Myers RM, Myin-Germeys I, Neale MC, Nelson SF, Nievergelt CM, Nikolov I, Nimgaonkar V, Nolen WA, Nothen MM, Nurnberger JI, Nwulia EA, Nyholt DR, O'Dushlaine C, Oades RD, Olincy A, Oliveira G, Olsen L, Ophoff RA, Osby U, Owen MJ, Palotie A, Parr JR, Paterson AD, Pato CN, Pato MT, Penninx BW, Pergadia ML, Pericak-Vance MA, Pickard BS, Pimm J, Piven J, Posthuma D, Potash JB, Poustka F, Propping P, Puri V, Quested DJ, Quinn EM, Ramos-Quiroga JA, Rasmussen HB, Raychaudhuri S, Rehnstrom K, Reif A, Ribases M, Rice JP, Rietschel M, Roeder K, Roeyers H, Rossin L, Rothenberger A, Rouleau G, Ruderfer D, Rujescu D, Sanders AR, Sanders SJ, Santangelo SL, Sergeant JA, Schachar R, Schalling M, Schatzberg AF, Scheftner WA, Schellenberg GD, Scherer SW, Schork NJ, Schulze TG, Schumacher J, Schwarz M, Scolnick E, Scott LJ, Shi J, Shilling PD, Shyn SI, Silverman JM, Slager SL, Smalley SL, Smit JH, Smith EN, Sonuga-Barke EJ, St Clair D, State M, Steffens M, Steinhausen HC, Strauss JS, Strohmaier J, Stroup TS, Sutcliffe JS, Szatmari P, Szelinger S, Thirumalai S, Thompson RC, Todorov AA, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, Van Os J, Vicente AM, Vieland VJ, Vincent JB, Visscher PM, Walsh CA, Wassink TH, Watson SJ, Weissman MM, Werge T, Wienker TF, Wijsman EM, Willemsen G, Williams N, Willsey AJ, Witt SH, Xu W, Young AH, Yu TW, Zammit S, Zandi PP, Zhang P, Zitman FG, Zollner S, International Inflammatory Bowel Disease Genetics C, Devlin B, Kelsoe JR, Sklar P, Daly MJ, O'Donovan MC, Craddock N, Sullivan PF, Smoller JW, Kendler KS and Wray NR: Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet 2013, 45 (9):984-94. doi: 10.1038/ng.2711. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/23933821
  • Garding A, Bhattacharya N, Claus R, Ruppel M, Tschuch C, Filarsky K, Idler I, Zucknick M, Caudron-Herger M, Oakes C, Fleig V, Keklikoglou I, Allegra D, Serra L, Thakurela S, Tiwari V, Weichenhan D, Benner A, Radlwimmer B, Zentgraf H, Wiemann S, Rippe K, Plass C, Dohner H, Lichter P, Stilgenbauer S and Mertens D: Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB. PLoS Genet 2013, 9 (4):e1003373. doi: 10.1371/journal.pgen.1003373. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/23593011
  • Gotschel F, Berg D, Gruber W, Bender C, Eberl M, Friedel M, Sonntag J, Rungeler E, Hache H, Wierling C, Nietfeld W, Lehrach H, Frischauf A, Schwartz-Albiez R, Aberger F and Korf U: Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1. PLoS One 2013, 8 (6):e65403. doi: 10.1371/journal.pone.0065403. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/23762360
  • Horvat EA, Zhang JD, Uhlmann S, Sahin O and Zweig KA: A network-based method to assess the statistical significance of mild co-regulation effects. PLoS One 2013, 8 (9):e73413. doi: 10.1371/journal.pone.0073413. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24039936
  • Issa A, Gill JW, Heideman MR, Sahin O, Wiemann S, Dey JH and Hynes NE: Combinatorial targeting of FGF and ErbB receptors blocks growth and metastatic spread of breast cancer models. Breast Cancer Res 2013, 15 (1):R8. doi: 10.1186/bcr3379. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/23343422
  • Korner C, Keklikoglou I, Bender C, Worner A, Munstermann E and Wiemann S: MicroRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C epsilon (PKCepsilon). J Biol Chem 2013, 288 (12):8750-61. doi: 10.1074/jbc.M112.414128. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/23364795
  • Kostler WJ, Zeisel A, Korner C, Tsai JM, Jacob-Hirsch J, Ben-Chetrit N, Sharma K, Cohen-Dvashi H, Yitzhaky A, Lader E, Tschulena U, Rechavi G, Domany E, Wiemann S and Yarden Y: Epidermal growth-factor-induced transcript isoform variation drives mammary cell migration. PLoS One 2013, 8 (12):e80566. doi: 10.1371/journal.pone.0080566. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/24324612
  • Shahmoradgoli M, Riazalhosseini Y, Haag D, Becker N, Hovestadt V, Heck S, Sinn HP, Schneeweiss A, Mannherz O, Sahin O and Lichter P: Protein phosphatase 1, regulatory subunit 15B is a survival factor for ERalpha-positive breast cancer. Int J Cancer 2013, 132 (11):2714-9. doi: 10.1002/ijc.27945. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/23169272
  • Vorstman JA, Anney RJ, Derks EM, Gallagher L, Gill M, de Jonge MV, van Engeland H, Kahn RS, Ophoff RA and Autism Genome Project tISC: No evidence that common genetic risk variation is shared between schizophrenia and autism. Am J Med Genet B Neuropsychiatr Genet 2013, 162B (1):55-60. doi: 10.1002/ajmg.b.32121. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/23193033
  • Ward A, Balwierz A, Zhang JD, Kublbeck M, Pawitan Y, Hielscher T, Wiemann S and Sahin O: Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer. Oncogene 2013, 32 (9):1173-82. doi: 10.1038/onc.2012.128. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22508479
  • Zeisel A, Yitzhaky A, Koerner C, Lauriola M, Cohen-Dvashi H, Kostler WJ, Yarden Y, Wiemann S and Domany E: qCMA: a desktop application for quantitative collective cell migration analysis. J Biomol Screen 2013, 18 (3):356-60. doi: 10.1177/1087057112461940. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/23042078

2012

  • Anney R, Klei L, Pinto D, Almeida J, Bacchelli E, Baird G, Bolshakova N, Bolte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Casey J, Conroy J, Correia C, Corsello C, Crawford EL, de Jonge M, Delorme R, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Gilbert J, Gillberg C, Glessner JT, Green A, Green J, Guter SJ, Heron EA, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Jacob S, Kenny GP, Kim C, Kolevzon A, Kustanovich V, Lajonchere CM, Lamb JA, Law-Smith M, Leboyer M, Le Couteur A, Leventhal BL, Liu XQ, Lombard F, Lord C, Lotspeich L, Lund SC, Magalhaes TR, Mantoulan C, McDougle CJ, Melhem NM, Merikangas A, Minshew NJ, Mirza GK, Munson J, Noakes C, Nygren G, Papanikolaou K, Pagnamenta AT, Parrini B, Paton T, Pickles A, Posey DJ, Poustka F, Ragoussis J, Regan R, Roberts W, Roeder K, Roge B, Rutter ML, Schlitt S, Shah N, Sheffield VC, Soorya L, Sousa I, Stoppioni V, Sykes N, Tancredi R, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Vorstman JA, Wallace S, Wing K, Wittemeyer K, Wood S, Zurawiecki D, Zwaigenbaum L, Bailey AJ, Battaglia A, Cantor RM, Coon H, Cuccaro ML, Dawson G, Ennis S, Freitag CM, Geschwind DH, Haines JL, Klauck SM, McMahon WM, Maestrini E, Miller J, Monaco AP, Nelson SF, Nurnberger JI Jr, Oliveira G, Parr JR, Pericak-Vance MA, Piven J, Schellenberg GD, Scherer SW, Vicente AM, Wassink TH, Wijsman EM, Betancur C, Buxbaum JD, Cook EH, Gallagher L, Gill M, Hallmayer J, Paterson AD, Sutcliffe JS, Szatmari P, Vieland VJ, Hakonarson H, Devlin B (2012) Individual common variants exert weak effects on the risk for autism spectrum disorderspi. Human Molecular Genetics 21(21):4781-92. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22843504
  • Botla SK, Gholami AM, Malekpour M, Moskalev EA, Fallah M, Jandaghi P, Aghajani A, Bondar IS, Omranipour R, Malekpour F, Mohajeri A, Babadi AJ, Sahin O, Bubnov VV, Najmabadi H, Hoheisel JD, Riazalhosseini Y (2012) Diagnostic values of GHSR DNA methylation pattern in breast cancer. Breast Cancer Research and Treatment 135(3):705-13. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22899222
  • Casey JP, Magalhaes T, Conroy JM, Regan R, Shah N, Anney R, Shields DC, Abrahams BS, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, Bolton PF, Bourgeron T, Brennan S, Cali P, Correia C, Corsello C, Coutanche M, Dawson G, de Jonge M, Delorme R, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Foley S, Fombonne E, Freitag CM, Gilbert J, Gillberg C, Glessner JT, Green J, Guter SJ, Hakonarson H, Holt R, Hughes G, Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Lamb JA, Leboyer M, Le Couteur A, Leventhal BL, Lord C, Lund SC, Maestrini E, Mantoulan C, Marshall CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Merikangas A, Miller J, Minopoli F, Mirza GK, Munson J, Nelson SF, Nygren G, Oliveira G, Pagnamenta AT, Papanikolaou K, Parr JR, Parrini B, Pickles A, Pinto D, Piven J, Posey DJ, Poustka A, Poustka F, Ragoussis J, Roge B, Rutter ML, Sequeira AF, Soorya L, Sousa I, Sykes N, Stoppioni V, Tancredi R, Tauber M, Thompson AP, Thomson S, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Vorstman JA, Wallace S, Wang K, Wassink TH, White K, Wing K, Wittemeyer K, Yaspan BL, Zwaigenbaum L, Betancur C, Buxbaum JD, Cantor RM, Cook EH, Coon H, Cuccaro ML, Geschwind DH, Haines JL, Hallmayer J, Monaco AP, Nurnberger JI, Jr., Pericak-Vance MA, Schellenberg GD, Scherer SW, Sutcliffe JS, Szatmari P, Vieland VJ, Wijsman EM, Green A, Gill M, Gallagher L, Vicente A, Ennis S (2012) A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Hum Genet 131: 565-579. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21996756
  • Florkowska M, Tymoszuk P, Balwierz A, Skucha A, Kochan J, Wawro M, Stalinska K, Kasza A (2012) EGF activates TTP expression by activation of ELK-1 and EGR-1 transcription factors. BMC Molecular Biology 13:8. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22433566
  • Gottschling S, Jauch A, Kuner R, Herpel E, Mueller-Decker K, Schnabel PA, Xu EC, Muley T, Sueltmann H, Bender C, Granzow M, Efferth T, Hoffmann H, Dienemann H, Herth FJ, Meister M (2012) Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue. Lung Cancer 75(1):45-57. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21684623
  • Henjes F, Bender C, von der Heyde S, Braun L, Mannsperger H, Schmidt C, Wiemann S, Hasmann M, Aulmann S, Beissbarth T, Korf U (2012) Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs. Oncogenesis 1: e16. Pubmed: http://www.nature.com/oncsis/journal/v1/n7/full/oncsis201216a.html
  • Jones DT, Jager N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stutz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, Pleier S, Cin H, Pfaff E, Sieber L, Wittmann A, Remke M, Witt H, Hutter S, Tzaridis T, Weischenfeldt J, Raeder B, Avci M, Amstislavskiy V, Zapatka M, Weber UD, Wang Q, Lasitschka B, Bartholomae CC, Schmidt M, von Kalle C, Ast V, Lawerenz C, Eils J, Kabbe R, Benes V, van Sluis P, Koster J, Volckmann R, Shih D, Betts MJ, Russell RB, Coco S, Tonini GP, Schuller U, Hans V, Graf N, Kim YJ, Monoranu C, Roggendorf W, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, von Deimling A, Witt O, Maass E, Rossler J, Ebinger M, Schuhmann MU, Fruhwald MC, Hasselblatt M, Jabado N, Rutkowski S, von Bueren AO, Williamson D, Clifford SC, McCabe MG, Collins VP, Wolf S, Wiemann S, Lehrach H, Brors B, Scheurlen W, Felsberg J, Reifenberger G, Northcott PA, Taylor MD, Meyerson M, Pomeroy SL, Yaspo ML, Korbel JO, Korshunov A, Eils R, Pfister SM, Lichter P (2012) Dissecting the genomic complexity underlying medulloblastoma. Nature 488(7409):100-105. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22832583
  • Jozefczuk J, Kashofer K, Ummanni R, Henjes F, Rehman S, Geenen S, Wruck W, Regenbrecht C, Daskalaki A, Wierling C, Turano P, Bertini I, Korf U, Zatloukal K, Westerhoff HV, Lehrach H, Adjaye J (2012) A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells. Frontiers in Physiology 3:339. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22969728
  • Jurmeister S, Baumann M, Balwierz A, Keklikoglou I, Ward A, Uhlmann S, Zhang JD, Wiemann S, Sahin O (2012) MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. Mol Cell Biol 32: 633-651. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22144583
  • Jurmeister S, Uhlmann S, Sahin Ö. MIR200C (microRNA 200c). Atlas Genet Cytogent Oncol Haematol.16 (2) 92-99. URL : http://AtlasGeneticsOncology.org/Genes/MIR200CID51054ch12p13.html
  • Kahn N, Meister M, Eberhardt R, Muley T, Schnabel P-A, Bender C, Johannes M, Keitel D, Sueltmann H, Herth FJF, Kuner R (2012) Early Detection of Lung Cancer by Molecular Markers in Endobronchial Epithelial-Lining Fluid. Journal of Thoracic Oncology 7(6):1001-8. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22588153
  • Keklikoglou I, Koerner C, Schmidt C, Zhang JD, Heckmann D, Shavinskaya A, Allgayer H, Guckel B, Fehm T, Schneeweiss A, Sahin O, Wiemann S, Tschulena U (2012) MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kappaB and TGF-beta signaling pathways. Oncogene 31(37):4150-63. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22158050
  • Leblond CS, Heinrich J, Delorme R, Proepper C, Betancur C, Huguet G, Konyukh M, Chaste P, Ey E, Rastam M, Anckarsater H, Nygren G, Gillberg IC, Melke J, Toro R, Regnault B, Fauchereau F, Mercati O, Lemiere N, Skuse D, Poot M, Holt R, Monaco AP, Jarvela I, Kantojarvi K, Vanhala R, Curran S, Collier DA, Bolton P, Chiocchetti A, Klauck SM, Poustka F, Freitag CM, Waltes R, Kopp M, Duketis E, Bacchelli E, Minopoli F, Ruta L, Battaglia A, Mazzone L, Maestrini E, Sequeira AF, Oliveira B, Vicente A, Oliveira G, Pinto D, Scherer SW, Zelenika D, Delepine M, Lathrop M, Bonneau D, Guinchat V, Devillard F, Assouline B, Mouren MC, Leboyer M, Gillberg C, Boeckers TM, Bourgeron T (2012) Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders. PLoS Genet 8: e1002521. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22346768
  • Lisauskas T, Matula P, Claas C, Reusing S, Wiemann S, Erfle H, Lehmann L, Fischer P, Eils R, Rohr K, Storrie B, Starkuviene V (2012) Live-cell assays to identify regulators of ER-to-Golgi trafficking. Traffic 13: 416-432. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22132776
  • Malinowsky K, Wolff C, Berg D, Schuster T, Walch A, Bronger H, Mannsperger H, Schmidt C, Korf U, Hofler H, Becker KF (2012) uPA and PAI-1-Related Signaling Pathways Differ between Primary Breast Cancers and Lymph Node Metastases. Transl Oncol 5: 98-104. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22496926
  • Nelson LD, Bender C, Mannsperger H, Buergy D, Kambakamba P, Mudduluru G, Korf U, Hughes D, Van Dyke MW, Allgayer H (2012) Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer. Mol Cancer 11: 38. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22682314
  • Schlecker E, Stojanovic A, Eisen C, Quack C, Falk CS, Umansky V, Cerwenka A (2012) Tumor-Infiltrating Monocytic Myeloid-Derived Suppressor Cells Mediate CCR5-Dependent Recruitment of Regulatory T Cells Favoring Tumor Growth. Journal of Immunology 189(12):5602-11. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/23152559
  • Shahmoradgoli, M.*, Riazalhosseini, Y.*, Haag, D., Becker, N., Hovestadt, V., Heck, S., Sinn, H.P., Schneeweiss, A., Mannherz, O., Sahin, Ö., Lichter, P. (*= equal contribution): Protein phosphatase 1, regulatory subunit 15B is a survival factor for ER alpha-positive breast cancer. International Journal of Cancer 2012. http://http://www.ncbi.nlm.nih.gov/pubmed/23169272
  • Shamu CE, Wiemann S, Boutros M (2012) On target: a public repository for large-scale RNAi experiments. Nat Cell Biol 14: 115. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22298037
  • Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Heriche JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R (2012) Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. Nat Cell Biol 14: 764-774. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22660414
  • Spaich S, Will RD, Just S, Kuhn C, Frank D, Berger I, Wiemann S, Korn B, Koegl M, Backs J, Katus HA, Rottbauer W, Frey N (2012) Fbxl22, a cardiac-enriched F-box protein, regulates sarcomeric protein turnover and is essential for maintenance of contractile function in vivo. Circulation Research Epub Sep 12. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22972877
  • Uhlmann S, Mannsperger H, Zhang JD, Horvat EA, Schmidt C, Kublbeck M, Henjes F, Ward A, Tschulena U, Zweig K, Korf U, Wiemann S, Sahin O (2012) Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer. Mol Syst Biol 8: 570. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22333974
  • Ummanni R, Barreto F, Venz S, Scharf C, Barett C, Mannsperger HA, Brase JC, Kuner R, Schlomm T, Sauter G, Sultmann H, Korf U, Bokemeyer C, Walther R, Brummendorf TH, Balabanov S (2012) Peroxiredoxins 3 and 4 are overexpressed in prostate cancer tissue and affect the proliferation of prostate cancer cells in vitro. J Proteome Res 11: 2452-2466. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22424448
  • Walde S, Thakar K, Hutten S, Spillner C, Nath A, Rothbauer U, Wiemann S, Kehlenbach RH (2012) The nucleoporin Nup358/RanBP2 promotes nuclear import in a cargo- and transport receptor-specific manner. Traffic 13: 218-233. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21995724

2011

  • Anney RJ, Kenny EM, O'Dushlaine C, Yaspan BL, Parkhomenka E, Buxbaum JD, Sutcliffe J, Gill M, Gallagher L, Bailey AJ, Fernandez BA, Szatmari P, Scherer SW, Patterson A, Marshall CR, Pinto D, Vincent JB, Fombonne E, Betancur C, Delorme R, Leboyer M, Bourgeron T, Mantoulan C, Roge B, Tauber M, Freitag CM, Poustka F, Duketis E, Klauck SM, Poustka A, Papanikolaou K, Tsiantis J, Anney R, Bolshakova N, Brennan S, Hughes G, McGrath J, Merikangas A, Ennis S, Green A, Casey JP, Conroy JM, Regan R, Shah N, Maestrini E, Bacchelli E, Minopoli F, Stoppioni V, Battaglia A, Igliozzi R, Parrini B, Tancredi R, Oliveira G, Almeida J, Duque F, Vicente A, Correia C, Magalhaes TR, Gillberg C, Nygren G, Jonge MD, Van Engeland H, Vorstman JA, Wittemeyer K, Baird G, Bolton PF, Rutter ML, Green J, Lamb JA, Pickles A, Parr JR, Couteur AL, Berney T, McConachie H, Wallace S, Coutanche M, Foley S, White K, Monaco AP, Holt R, Farrar P, Pagnamenta AT, Mirza GK, Ragoussis J, Sousa I, Sykes N, Wing K, Hallmayer J, Cantor RM, Nelson SF, Geschwind DH, Abrahams BS, Volkmar F, Pericak-Vance MA, Cuccaro ML, Gilbert J, Cook EH, Guter SJ, Jacob S, Nurnberger Jr JI, McDougle CJ, Posey DJ, Lord C, Corsello C, Hus V, Kolevzon A, Soorya L, Parkhomenko E, Leventhal BL, Dawson G, Vieland VJ, Hakonarson H, Glessner JT, Kim C, Wang K, Schellenberg GD, Devlin B, Klei L, Minshew N, Sutcliffe JS, Haines JL, Lund SC, Thomson S, Coon H, Miller J, McMahon WM, Munson J, Estes A, Wijsman EM (2011) Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders. Eur J Hum Genet. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21522181
  • Bai SW, Herrera-Abreu MT, Rohn JL, Racine V, Tajadura V, Suryavanshi N, Bechtel S, Wiemann S, Baum B, Ridley AJ (2011) Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration. BMC Biol 9: 54. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21834987
  • Bender C, Heyde S, Henjes F, Wiemann S, Korf U, Beissbarth T (2011) Inferring signalling networks from longitudinal data using sampling based approaches in the R-package 'ddepn'. BMC Bioinformatics 12: 291. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21771315
  • Brase JC, Johannes M, Mannsperger H, Falth M, Metzger J, Kacprzyk LA, Andrasiuk T, Gade S, Meister M, Sirma H, Sauter G, Simon R, Schlomm T, Beissbarth T, Korf U, Kuner R, Sultmann H (2011a) TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-beta signaling. BMC Cancer 11: 507. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22142399
  • Brase JC, Johannes M, Schlomm T, Falth M, Haese A, Steuber T, Beissbarth T, Kuner R, Sultmann H (2011b) Circulating miRNAs are correlated with tumor progression in prostate cancer. Int J Cancer 128: 608-616. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20473869
  • Brase JC, Mannsperger H, Sultmann H, Korf U (2011c) Antibody-mediated signal amplification for reverse phase protein array-based protein quantification. Methods Mol Biol 785: 55-64. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21901593
  • Bu H, Bormann S, Schafer G, Horninger W, Massoner P, Neeb A, Lakshmanan VK, Maddalo D, Nestl A, Sultmann H, Cato AC, Klocker H (2011) The anterior gradient 2 (AGR2) gene is overexpressed in prostate cancer and may be useful as a urine sediment marker for prostate cancer detection. Prostate 71: 575-587. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20945500
  • Chiocchetti A, Klauck SM (2011) [Genetic analyses for identifying molecular mechanisms in autism spectrum disorders]. Z Kinder Jugendpsychiatr Psychother 39: 101-111. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21442598
  • Chiocchetti A, Pakalapati G, Duketis E, Wiemann S, Poustka A, Poustka F, Klauck SM (2011) Mutation and expression analyses of the ribosomal protein gene RPL10 in an extended German sample of patients with autism spectrum disorder. Am J Med Genet A 155A: 1472-1475. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21567917
  • Curran S, Bolton P, Rozsnyai K, Chiocchetti A, Klauck SM, Duketis E, Poustka F, Schlitt S, Freitag CM, Lee I, Muglia P, Poot M, Staal W, de Jonge MV, Ophoff RA, Lewis C, Skuse D, Mandy W, Vassos E, Fossdal R, Magnusson P, Hreidarsson S, Saemundsen E, Stefansson H, Stefansson K, Collier D (2011) No association between a common single nucleotide polymorphism, rs4141463, in the MACROD2 Gene and Autism Spectrum Disorder. Am J Med Genet B Neuropsychiatr Genet. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21656903
  • El Debs BW, Tschulena U, Griffiths AD, Merten CA (2011) A competitive co-cultivation assay for cancer drug specificity evaluation. J Biomol Screen 16: 818-824. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21788393
  • Fussbroich B, Wagener N, Macher-Goeppinger S, Benner A, Falth M, Sultmann H, Holzer A, Hoppe-Seyler K, Hoppe-Seyler F (2011) EZH2 depletion blocks the proliferation of colon cancer cells. PLoS One 6: e21651. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21765901
  • Gade S, Porzelius C, Faelth M, Brase JC, Wuttig D, Kuner R, Binder H, Sueltmann H, Beissbarth T (2011) Graph based fusion of miRNA and mRNA expression data improves clinical outcome prediction in prostate cancer. BMC Bioinformatics 12: 488. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/22188670
  • Hellwinkel OJ, Asong LE, Rogmann JP, Sultmann H, Wagner C, Schlomm T, Eichelberg C (2011) Transcription alterations of members of the ubiquitin-proteasome network in prostate carcinoma. Prostate Cancer Prostatic Dis 14: 38-45. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21102547
  • Henjes F, Gotschel F, Jocker A, Korf U (2011) Quantitative analysis of phosphoproteins using microspot immunoassays. Methods Mol Biol 785: 191-201. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21901601
  • Johannes M, Frohlich H, Sultmann H, Beissbarth T (2011) pathClass: an R-package for integration of pathway knowledge into support vector machines for biomarker discovery. Bioinformatics 27: 1442-1443. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21450711
  • Kerick M, Isau M, Timmermann B, Sultmann H, Herwig R, Krobitsch S, Schaefer G, Verdorfer I, Bartsch G, Klocker H, Lehrach H, Schweiger MR (2011) Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity. BMC Med Genomics 4: 68. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21958464
  • Klauck SM, Poustka L, Chiocchetti A (2011) [Genetics and animal modeling of autism spectrum disorders. New developments]. Nervenarzt 82: 553-562. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21472451
  • Luckert K, Gotschel F, Sorger PK, Hecht A, Joos TO, Potz O (2011) Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions. Mol Cell Proteomics 10: M110 007377. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21378377
  • Mannsperger H, Uhlmann S, Korf U, Sahin O (2011) Utilization of RNAi to validate antibodies for reverse phase protein arrays. Methods Mol Biol 785: 45-54. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21901592
  • Minner S, Enodien M, Sirma H, Luebke AM, Krohn A, Mayer PS, Simon R, Tennstedt P, Muller J, Scholz L, Brase JC, Liu AY, Schluter H, Pantel K, Schumacher U, Bokemeyer C, Steuber T, Graefen M, Sauter G, Schlomm T (2011) ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy. Clin Cancer Res 17: 5878-5888. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21791629
  • Rupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marme F, Sultmann H, Altevogt P (2011) Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage. Gynecol Oncol 122: 437-446. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21601258
  • Schetelig MF, Gotschel F, Viktorinova I, Handler AM, Wimmer EA (2011) Recombination technologies for enhanced transgene stability in bioengineered insects. Genetica 139: 71-78. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20844938
  • Sonntag J, Mannsperger H, Jocker A, Korf U (2011) Microspot immunoassay-based analysis of plasma protein profiles for biomarker discovery strategies. Methods Mol Biol 785: 237-245. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21901604
  • Tschulena U, Sanzenbacher R, Muhlebach MD, Berger A, Munch J, Schindler M, Kirchhoff F, Plesker R, Coulibaly C, Panitz S, Prufer S, Muckenfuss H, Hamdorf M, Schweizer M, Cichutek K, Flory E (2011) Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease. Retrovirology 8: 14. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21366921
  • Ummanni R, Jost E, Braig M, Lohmann F, Mundt F, Barett C, Schlomm T, Sauter G, Senff T, Bokemeyer C, Sultmann H, Meyer-Schwesinger C, Brummendorf TH, Balabanov S (2011a) Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation. Mol Cancer 10: 129. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21999842
  • Ummanni R, Mundt F, Pospisil H, Venz S, Scharf C, Barett C, Falth M, Kollermann J, Walther R, Schlomm T, Sauter G, Bokemeyer C, Sultmann H, Schuppert A, Brummendorf TH, Balabanov S (2011b) Identification of clinically relevant protein targets in prostate cancer with 2D-DIGE coupled mass spectrometry and systems biology network platform. PLoS One 6: e16833. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21347291
  • Warth A, Muley T, Meister M, Herpel E, Pathil A, Hoffmann H, Schnabel PA, Bender C, Buness A, Schirmacher P, Kuner R (2011) Loss of aquaporin-4 expression and putative function in non-small cell lung cancer. BMC Cancer 11: 161. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21548930
  • Wittig-Blaich SM, Kacprzyk LA, Eismann T, Bewerunge-Hudler M, Kruse P, Winkler E, Strauss WS, Hibst R, Steiner R, Schrader M, Mertens D, Sultmann H, Wittig R (2011) Matrix-dependent regulation of AKT in Hepsin-overexpressing PC3 prostate cancer cells. Neoplasia 13: 579-589. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21750652
  • Zhang JD, Koerner C, Bechtel S, Bender C, Keklikoglou I, Schmidt C, Irsigler A, Ernst U, Sahin O, Wiemann S, Tschulena U (2011) Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation. PLoS One 6: e22176. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21765947

2010

  • Anney R, Klei L, Pinto D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Sykes N, Pagnamenta AT, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, Bolte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Carson AR, Casallo G, Casey J, Chu SH, Cochrane L, Corsello C, Crawford EL, Crossett A, Dawson G, de Jonge M, Delorme R, Drmic I, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Freitag CM, Gilbert J, Gillberg C, Glessner JT, Goldberg J, Green J, Guter SJ, Hakonarson H, Heron EA, Hill M, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Korvatska O, Kustanovich V, Lajonchere CM, Lamb JA, Laskawiec M, Leboyer M, Le Couteur A, Leventhal BL, Lionel AC, Liu XQ, Lord C, Lotspeich L, Lund SC, Maestrini E, Mahoney W, Mantoulan C, Marshall CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Melhem NM, Merikangas A, Migita O, Minshew NJ, Mirza GK, Munson J, Nelson SF, Noakes C, Noor A, Nygren G, Oliveira G, Papanikolaou K, Parr JR, Parrini B, Paton T, Pickles A, Piven J, Posey DJ, Poustka A, Poustka F, Prasad A, Ragoussis J, Renshaw K, Rickaby J, Roberts W, Roeder K, Roge B, Rutter ML, Bierut LJ, Rice JP, Salt J, Sansom K, Sato D, Segurado R, Senman L, Shah N, Sheffield VC, Soorya L, Sousa I, Stoppioni V, Strawbridge C, Tancredi R, Tansey K, Thiruvahindrapduram B, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Wallace S, Wang K, Wang Z, Wassink TH, Wing K, Wittemeyer K, Wood S, Yaspan BL, Zurawiecki D, Zwaigenbaum L, Betancur C, Buxbaum JD, Cantor RM, Cook EH, Coon H, Cuccaro ML, Gallagher L, Geschwind DH, Gill M, Haines JL, Miller J, Monaco AP, Nurnberger JI, Jr., Paterson AD, Pericak-Vance MA, Schellenberg GD, Scherer SW, Sutcliffe JS, Szatmari P, Vicente AM, Vieland VJ, Wijsman EM, Devlin B, Ennis S, Hallmayer J (2010) A genome-wide scan for common alleles affecting risk for autism. Hum Mol Genet 19: 4072-4082. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20663923
  • Bender C, Henjes F, Frohlich H, Wiemann S, Korf U, Beissbarth T (2010) Dynamic deterministic effects propagation networks: learning signalling pathways from longitudinal protein array data. Bioinformatics 26: i596-602. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20823327
  • Brase JC, Mannsperger H, Frohlich H, Gade S, Schmidt C, Wiemann S, Beissbarth T, Schlomm T, Sultmann H, Korf U (2010a) Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification. Proteome Sci 8: 36. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20569466
  • Brase JC, Schmidt M, Fischbach T, Sultmann H, Bojar H, Koelbl H, Hellwig B, Rahnenfuhrer J, Hengstler JG, Gehrmann MC (2010b) ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and prediction. Clin Cancer Res 16: 2391-2401. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20371687
  • Brase JC, Wuttig D, Kuner R, Sultmann H (2010c) Serum microRNAs as non-invasive biomarkers for cancer. Mol Cancer 9: 306. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21110877
  • de Souza Rocha Simonini P, Breiling A, Gupta N, Malekpour M, Youns M, Omranipour R, Malekpour F, Volinia S, Croce CM, Najmabadi H, Diederichs S, Sahin O, Mayer D, Lyko F, Hoheisel JD, Riazalhosseini Y (2010) Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells. Cancer Res 70: 9175-9184. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20978187
  • Freitag CM, Staal W, Klauck SM, Duketis E, Waltes R (2010) Genetics of autistic disorders: review and clinical implications. Eur Child Adolesc Psychiatry 19: 169-178. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/19941018
  • Haller F, von Heydebreck A, Zhang JD, Gunawan B, Langer C, Ramadori G, Wiemann S, Sahin O (2010a) Localization- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co-expressed miRNAs located at 14q32.31. J Pathol 220: 71-86. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/19768731
  • Haller F, Zhang DJ, Lobke C, von Heydebreck A, Korf U, Fuzesi L, Sahin O (2010b) [Multilayer analysis of signal transduction and cell cycle control in GIST. Identifying new interaction partners with differential regulation]. Pathologe 31 Suppl 2: 134-137. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20714898
  • Holt R, Barnby G, Maestrini E, Bacchelli E, Brocklebank D, Sousa I, Mulder EJ, Kantojarvi K, Jarvela I, Klauck SM, Poustka F, Bailey AJ, Monaco AP (2010) Linkage and candidate gene studies of autism spectrum disorders in European populations. Eur J Hum Genet 18: 1013-1019. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20442744
  • Jocker A, Sonntag J, Henjes F, Gotschel F, Tresch A, Beissbarth T, Wiemann S, Korf U (2010) QuantProReloaded: quantitative analysis of microspot immunoassays. Bioinformatics 26: 2480-2481. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20709689
  • Johannes M, Brase JC, Frohlich H, Gade S, Gehrmann M, Falth M, Sultmann H, Beissbarth T (2010) Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients. Bioinformatics 26: 2136-2144. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20591905
  • Maestrini E, Pagnamenta AT, Lamb JA, Bacchelli E, Sykes NH, Sousa I, Toma C, Barnby G, Butler H, Winchester L, Scerri TS, Minopoli F, Reichert J, Cai G, Buxbaum JD, Korvatska O, Schellenberg GD, Dawson G, de Bildt A, Minderaa RB, Mulder EJ, Morris AP, Bailey AJ, Monaco AP (2010) High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. Mol Psychiatry 15: 954-968. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/19401682
  • Mannsperger HA, Gade S, Henjes F, Beissbarth T, Korf U (2010a) RPPanalyzer: Analysis of reverse-phase protein array data. Bioinformatics 26: 2202-2203. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20634205
  • Mannsperger HA, Uhlmann S, Schmidt C, Wiemann S, Sahin O, Korf U (2010b) RNAi-based validation of antibodies for reverse phase protein arrays. Proteome Sci 8: 69. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/21182776
  • Noor A, Whibley A, Marshall CR, Gianakopoulos PJ, Piton A, Carson AR, Orlic-Milacic M, Lionel AC, Sato D, Pinto D, Drmic I, Noakes C, Senman L, Zhang X, Mo R, Gauthier J, Crosbie J, Pagnamenta AT, Munson J, Estes AM, Fiebig A, Franke A, Schreiber S, Stewart AF, Roberts R, McPherson R, Guter SJ, Cook EH, Jr., Dawson G, Schellenberg GD, Battaglia A, Maestrini E, Autism Genome Project Consortium, Jeng L, Hutchison T, Rajcan-Separovic E, Chudley AE, Lewis SM, Liu X, Holden JJ, Fernandez B, Zwaigenbaum L, Bryson SE, Roberts W, Szatmari P, Gallagher L, Stratton MR, Gecz J, Brady AF, Schwartz CE, Schachar RJ, Monaco AP, Rouleau GA, Hui CC, Lucy Raymond F, Scherer SW, Vincent JB (2010) Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability. Sci Transl Med 2: 49ra68. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20844286
  • Pagnamenta AT, Bacchelli E, de Jonge MV, Mirza G, Scerri TS, Minopoli F, Chiocchetti A, Ludwig KU, Hoffmann P, Paracchini S, Lowy E, Harold DH, Chapman JA, Klauck SM, Poustka F, Houben RH, Staal WG, Ophoff RA, O'Donovan MC, Williams J, Nothen MM, Schulte-Korne G, Deloukas P, Ragoussis J, Bailey AJ, Maestrini E, Monaco AP (2010) Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. Biol Psychiatry 68: 320-328. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20346443
  • Pinto D, Pagnamenta AT, Klei L, Anney R, Merico D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Almeida J, Bacchelli E, Bader GD, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, Bolte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Bryson SE, Carson AR, Casallo G, Casey J, Chung BH, Cochrane L, Corsello C, Crawford EL, Crossett A, Cytrynbaum C, Dawson G, de Jonge M, Delorme R, Drmic I, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Freitag CM, Gilbert J, Gillberg C, Glessner JT, Goldberg J, Green A, Green J, Guter SJ, Hakonarson H, Heron EA, Hill M, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Korvatska O, Kustanovich V, Lajonchere CM, Lamb JA, Laskawiec M, Leboyer M, Le Couteur A, Leventhal BL, Lionel AC, Liu XQ, Lord C, Lotspeich L, Lund SC, Maestrini E, Mahoney W, Mantoulan C, Marshall CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Merikangas A, Migita O, Minshew NJ, Mirza GK, Munson J, Nelson SF, Noakes C, Noor A, Nygren G, Oliveira G, Papanikolaou K, Parr JR, Parrini B, Paton T, Pickles A, Pilorge M, Piven J, Ponting CP, Posey DJ, Poustka A, Poustka F, Prasad A, Ragoussis J, Renshaw K, Rickaby J, Roberts W, Roeder K, Roge B, Rutter ML, Bierut LJ, Rice JP, Salt J, Sansom K, Sato D, Segurado R, Sequeira AF, Senman L, Shah N, Sheffield VC, Soorya L, Sousa I, Stein O, Sykes N, Stoppioni V, Strawbridge C, Tancredi R, Tansey K, Thiruvahindrapduram B, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Wallace S, Wang K, Wang Z, Wassink TH, Webber C, Weksberg R, Wing K, Wittemeyer K, Wood S, Wu J, Yaspan BL, Zurawiecki D, Zwaigenbaum L, Buxbaum JD, Cantor RM, Cook EH, Coon H, Cuccaro ML, Devlin B, Ennis S, Gallagher L, Geschwind DH, Gill M, Haines JL, Hallmayer J, Miller J, Monaco AP, Nurnberger JI, Jr., Paterson AD, Pericak-Vance MA, Schellenberg GD, Szatmari P, Vicente AM, Vieland VJ, Wijsman EM, Scherer SW, Sutcliffe JS, Betancur C (2010) Functional impact of global rare copy number variation in autism spectrum disorders. Nature 466: 368-372. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20531469
  • Rostamiani K, Klauck SM, Heiss N, Poustka A, Khaleghi M, Rosales R, Metzenberg AB (2010) Novel mutations of the DKC1 gene in individuals affected with dyskeratosis congenita. Blood Cells Mol Dis 44: 88. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/19879169
  • Sousa I, Clark TG, Holt R, Pagnamenta AT, Mulder EJ, Minderaa RB, Bailey AJ, Battaglia A, Klauck SM, Poustka F, Monaco AP (2010) Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry. Mol Autism 1: 7. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20678249
  • Uhlmann S, Zhang JD, Schwager A, Mannsperger H, Riazalhosseini Y, Burmester S, Ward A, Korf U, Wiemann S, Sahin O (2010) miR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer. Oncogene 29: 4297-4306. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20514023
  • Wilber A, Tschulena U, Hargrove PW, Kim YS, Persons DA, Barbas CF, 3rd, Nienhuis AW (2010) A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts. Blood 115: 3033-3041. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20190190
  • Will RD, Eden M, Just S, Hansen A, Eder A, Frank D, Kuhn C, Seeger TS, Oehl U, Wiemann S, Korn B, Koegl M, Rottbauer W, Eschenhagen T, Katus HA, Frey N (2010) Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing. Circ Res 107: 1253-1264. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20847312
  • Youns M, Fu YJ, Zu YG, Kramer A, Konkimalla VB, Radlwimmer B, Sultmann H, Efferth T (2010) Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics. Naunyn Schmiedebergs Arch Pharmacol 382: 221-234. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/20668838

2009

2008

  • Boeuf S, Steck E, Pelttari K, Hennig T, Buness A, Benz K, Witte D, Sultmann H, Poustka A, Richter W (2008) Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers. Osteoarthritis Cartilage 16: 48-60. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17604188
  • Cheung W, Darfler MM, Alvarez H, Hood BL, Conrads TP, Habbe N, Krizman DB, Mollenhauer J, Feldmann G, Maitra A (2008) Application of a global proteomic approach to archival precursor lesions: deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors. Pancreatology 8: 608-616. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18849643
  • Eisenberger S, Ackermann K, Voggenreiter G, Sultmann H, Kasperk C, Pyerin W (2008) Metastases and multiple myeloma generate distinct transcriptional footprints in osteocytes in vivo. J Pathol 214: 617-626. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18266311
  • Frohlich H, Beissbarth T, Tresch A, Kostka D, Jacob J, Spang R, Markowetz F (2008a) Analyzing gene perturbation screens with nested effects models in R and bioconductor. Bioinformatics 24: 2549-2550. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18718939
  • Frohlich H, Fellmann M, Sultmann H, Poustka A, Beissbarth T (2008b) Estimating Large Scale Signaling Networks through Nested Effect Models with Intervention Effects from Microarray Data. Bioinformatics. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18227117
  • Frohlich H, Fellmann M, Sultmann H, Poustka A, Beissbarth T (2008c) Predicting pathway membership via domain signatures. Bioinformatics 24: 2137-2142. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18676972
  • Genome Information Integration P, Invitational H, Yamasaki C, Murakami K, Fujii Y, Sato Y, Harada E, Takeda J, Taniya T, Sakate R, Kikugawa S, Shimada M, Tanino M, Koyanagi KO, Barrero RA, Gough C, Chun HW, Habara T, Hanaoka H, Hayakawa Y, Hilton PB, Kaneko Y, Kanno M, Kawahara Y, Kawamura T, Matsuya A, Nagata N, Nishikata K, Noda AO, Nurimoto S, Saichi N, Sakai H, Sanbonmatsu R, Shiba R, Suzuki M, Takabayashi K, Takahashi A, Tamura T, Tanaka M, Tanaka S, Todokoro F, Yamaguchi K, Yamamoto N, Okido T, Mashima J, Hashizume A, Jin L, Lee KB, Lin YC, Nozaki A, Sakai K, Tada M, Miyazaki S, Makino T, Ohyanagi H, Osato N, Tanaka N, Suzuki Y, Ikeo K, Saitou N, Sugawara H, O'Donovan C, Kulikova T, Whitfield E, Halligan B, Shimoyama M, Twigger S, Yura K, Kimura K, Yasuda T, Nishikawa T, Akiyama Y, Motono C, Mukai Y, Nagasaki H, Suwa M, Horton P, Kikuno R, Ohara O, Lancet D, Eveno E, Graudens E, Imbeaud S, Debily MA, Hayashizaki Y, Amid C, Han M, Osanger A, Endo T, Thomas MA, Hirakawa M, Makalowski W, Nakao M, Kim NS, Yoo HS, De Souza SJ, Bonaldo Mde F, Niimura Y, Kuryshev V, Schupp I, Wiemann S, Bellgard M, Shionyu M, Jia L, Thierry-Mieg D, Thierry-Mieg J, Wagner L, Zhang Q, Go M, Minoshima S, Ohtsubo M, Hanada K, Tonellato P, Isogai T, Zhang J, Lenhard B, Kim S, Chen Z, Hinz U, Estreicher A, Nakai K, Makalowska I, Hide W, Tiffin N, Wilming L, Chakraborty R, Soares MB, Chiusano ML, Suzuki Y, Auffray C, Yamaguchi-Kabata Y, Itoh T, Hishiki T, Fukuchi S, Nishikawa K, Sugano S, Nomura N, Tateno Y, Imanishi T, Gojobori T (2008) The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res 36: D793-799. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18089548
  • Hahne F, Mehrle A, Arlt D, Poustka A, Wiemann S, Beissbarth T (2008) Extending pathways based on gene lists using InterPro domain signatures. BMC Bioinformatics 9: 3. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18177498
  • Haller F, Lobke C, Ruschhaupt M, Cameron S, Schulten HJ, Schwager S, von Heydebreck A, Gunawan B, Langer C, Ramadori G, Sultmann H, Poustka A, Korf U, Fuzesi L (2008a) Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs). J Pathol 215: 253-262. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18438954
  • Haller F, Lobke C, Ruschhaupt M, Schulten HJ, Schwager S, Gunawan B, Armbrust T, Langer C, Ramadori G, Sultmann H, Poustka A, Korf U, Fuzesi L (2008b) Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletions. J Pathol 216: 225-235. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18729075
  • Kissling C, Retz W, Wiemann S, Coogan AN, Clement RM, Hunnerkopf R, Conner AC, Freitag CM, Rosler M, Thome J (2008) A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 147: 333-338. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17948273
  • Kleber S, Sancho-Martinez I, Wiestler B, Beisel A, Gieffers C, Hill O, Thiemann M, Mueller W, Sykora J, Kuhn A, Schreglmann N, Letellier E, Zuliani C, Klussmann S, Teodorczyk M, Grone HJ, Ganten TM, Sultmann H, Tuttenberg J, von Deimling A, Regnier-Vigouroux A, Herold-Mende C, Martin-Villalba A (2008) Yes and PI3K bind CD95 to signal invasion of glioblastoma. Cancer Cell 13: 235-248. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18328427
  • Kohl T, Schmidt C, Wiemann S, Poustka A, Korf U (2008) Automated production of recombinant human proteins as resource for proteome research. Proteome Sci 6: 4. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18226205
  • Korf U, Derdak S, Tresch A, Henjes F, Schumacher S, Schmidt C, Hahn B, Lehmann WD, Poustka A, Beissbarth T, Klingmuller U (2008a) Quantitative protein microarrays for time-resolved measurements of protein phosphorylation. Proteomics 8: 4603-4612. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18972530
  • Korf U, Henjes F, Schmidt C, Tresch A, Mannsperger H, Lobke C, Beissbarth T, Poustka A (2008b) Antibody microarrays as an experimental platform for the analysis of signal transduction networks. Adv Biochem Eng Biotechnol 110: 153-175. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18528667
  • Kuner R, Barth AS, Ruschhaupt M, Buness A, Zwermann L, Kreuzer E, Steinbeck G, Poustka A, Sultmann H, Nabauer M (2008) Genomic analysis reveals poor separation of human cardiomyopathies of ischemic and nonischemic etiologies. Physiol Genomics 34: 88-94. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18430805
  • Lobke C, Laible M, Rappl C, Ruschhaupt M, Sahin O, Arlt D, Wiemann S, Poustka A, Sultmann H, Korf U (2008) Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling. Proteomics 8: 1586-1594. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18351692
  • Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Bjorling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, Bustelo XR, Cagney G, Cantin GT, Cardasis HL, Celis JE, Chaerkady R, Chu F, Cole PA, Costello CE, Cotter RJ, Crockett D, DeLany JP, De Marzo AM, DeSouza LV, Deutsch EW, Dransfield E, Drewes G, Droit A, Dunn MJ, Elenitoba-Johnson K, Ewing RM, Van Eyk J, Faca V, Falkner J, Fang X, Fenselau C, Figeys D, Gagne P, Gelfi C, Gevaert K, Gimble JM, Gnad F, Goel R, Gromov P, Hanash SM, Hancock WS, Harsha HC, Hart G, Hays F, He F, Hebbar P, Helsens K, Hermeking H, Hide W, Hjerno K, Hochstrasser DF, Hofmann O, Horn DM, Hruban RH, Ibarrola N, James P, Jensen ON, Jensen PH, Jung P, Kandasamy K, Kheterpal I, Kikuno RF, Korf U, Korner R, Kuster B, Kwon MS, Lee HJ, Lee YJ, Lefevre M, Lehvaslaiho M, Lescuyer P, Levander F, Lim MS, Lobke C, Loo JA, Mann M, Martens L, Martinez-Heredia J, McComb M, McRedmond J, Mehrle A, Menon R, Miller CA, Mischak H, Mohan SS, Mohmood R, Molina H, Moran MF, Morgan JD, Moritz R, Morzel M, Muddiman DC, Nalli A, Navarro JD, Neubert TA, Ohara O, Oliva R, Omenn GS, Oyama M, Paik YK, Pennington K, Pepperkok R, Periaswamy B, Petricoin EF, Poirier GG, Prasad TS, Purvine SO, Rahiman BA, Ramachandran P, Ramachandra YL, Rice RH, Rick J, Ronnholm RH, Salonen J, Sanchez JC, Sayd T, Seshi B, Shankari K, Sheng SJ, Shetty V, Shivakumar K, Simpson RJ, Sirdeshmukh R, Siu KW, Smith JC, Smith RD, States DJ, Sugano S, Sullivan M, Superti-Furga G, Takatalo M, Thongboonkerd V, Trinidad JC, Uhlen M, Vandekerckhove J, Vasilescu J, Veenstra TD, Vidal-Taboada JM, Vihinen M, Wait R, Wang X, Wiemann S, Wu B, Xu T, Yates JR, Zhong J, Zhou M, Zhu Y, Zurbig P, Pandey A (2008) Human Proteinpedia enables sharing of human protein data. Nat Biotechnol 26: 164-167. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18259167
  • Michaud J, Simpson KM, Escher R, Buchet-Poyau K, Beissbarth T, Carmichael C, Ritchie ME, Schutz F, Cannon P, Liu M, Shen X, Ito Y, Raskind WH, Horwitz MS, Osato M, Turner DR, Speed TP, Kavallaris M, Smyth GK, Scott HS (2008) Integrative analysis of RUNX1 downstream pathways and target genes. BMC Genomics 9: 363. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18671852
  • Muller H, End C, Weiss C, Renner M, Bhandiwad A, Helmke BM, Gassler N, Hafner M, Poustka A, Mollenhauer J, Poeschl J (2008) Respiratory Deleted in Malignant Brain Tumours 1 (DMBT1) levels increase during lung maturation and infection. Clin Exp Immunol 151: 123-129. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17991292
  • Pepperkok R, Wiemann S (2008) Integrating systems biology with clinical research. Genome Biol 9: 314. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18598389
  • Praml C, Schulz W, Claas A, Mollenhauer J, Poustka A, Ackermann R, Schwab M, Henrich KO (2008) Genetic variation of Aflatoxin B1 aldehyde reductase genes (AFAR) in human tumour cells. Cancer Lett 272: 160-166. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18752886
  • Retz W, Rosler M, Kissling C, Wiemann S, Hunnerkopf R, Coogan A, Thome J, Freitag C (2008) Norepinephrine transporter and catecholamine-O-methyltransferase gene variants and attention-deficit/hyperactivity disorder symptoms in adults. J Neural Transm 115: 323-329. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17994190
  • Sansone SA, Rocca-Serra P, Brandizi M, Brazma A, Field D, Fostel J, Garrow AG, Gilbert J, Goodsaid F, Hardy N, Jones P, Lister A, Miller M, Morrison N, Rayner T, Sklyar N, Taylor C, Tong W, Warner G, Wiemann S (2008) The first RSBI (ISA-TAB) workshop: "can a simple format work for complex studies?". Omics 12: 143-149. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18447634
  • Sauermann M, Sahin O, Sultmann H, Hahne F, Blaszkiewicz S, Majety M, Zatloukal K, Fuzesi L, Poustka A, Wiemann S, Arlt D (2008) Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells. Oncogene 27: 1320-1326. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17724469
  • Schlomm T, Nakel E, Lubke A, Buness A, Chun FK, Steuber T, Graefen M, Simon R, Sauter G, Poustka A, Huland H, Erbersdobler A, Sultmann H, Hellwinkel OJ (2008a) Marked gene transcript level alterations occur early during radical prostatectomy. Eur Urol 53: 333-346. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17448597
  • Schlomm T, Sultmann H, Kollermann J (2008b) [Identification and validation of clinically relevant molecular alterations in prostate cancer]. Urologe A 47: 1193-1198. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18712514
  • Stadler V, Felgenhauer T, Beyer M, Fernandez S, Leibe K, Guttler S, Groning M, Konig K, Torralba G, Hausmann M, Lindenstruth V, Nesterov A, Block I, Pipkorn R, Poustka A, Bischoff FR, Breitling F (2008) Combinatorial synthesis of peptide arrays with a laser printer. Angew Chem Int Ed Engl 47: 7132-7135. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18671222
  • Taylor CF, Field D, Sansone SA, Aerts J, Apweiler R, Ashburner M, Ball CA, Binz PA, Bogue M, Booth T, Brazma A, Brinkman RR, Michael Clark A, Deutsch EW, Fiehn O, Fostel J, Ghazal P, Gibson F, Gray T, Grimes G, Hancock JM, Hardy NW, Hermjakob H, Julian RK, Jr., Kane M, Kettner C, Kinsinger C, Kolker E, Kuiper M, Le Novere N, Leebens-Mack J, Lewis SE, Lord P, Mallon AM, Marthandan N, Masuya H, McNally R, Mehrle A, Morrison N, Orchard S, Quackenbush J, Reecy JM, Robertson DG, Rocca-Serra P, Rodriguez H, Rosenfelder H, Santoyo-Lopez J, Scheuermann RH, Schober D, Smith B, Snape J, Stoeckert CJ, Jr., Tipton K, Sterk P, Untergasser A, Vandesompele J, Wiemann S (2008) Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nat Biotechnol 26: 889-896. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18688244
  • Van Laere S, Beissbarth T, Van der Auwera I, Van den Eynden G, Trinh XB, Elst H, Van Hummelen P, van Dam P, Van Marck E, Vermeulen P, Dirix L (2008) Relapse-free survival in breast cancer patients is associated with a gene expression signature characteristic for inflammatory breast cancer. Clin Cancer Res 14: 7452-7460. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19010862
  • Westermann F, Muth D, Benner A, Bauer T, Henrich KO, Oberthuer A, Brors B, Beissbarth T, Vandesompele J, Pattyn F, Hero B, Konig R, Fischer M, Schwab M (2008) Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas. Genome Biol 9: R150. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18851746
  • Yamasaki C, Murakami K, Fujii Y, Sato Y, Harada E, Takeda J, Taniya T, Sakate R, Kikugawa S, Shimada M, Tanino M, Koyanagi KO, Barrero RA, Gough C, Chun HW, Habara T, Hanaoka H, Hayakawa Y, Hilton PB, Kaneko Y, Kanno M, Kawahara Y, Kawamura T, Matsuya A, Nagata N, Nishikata K, Noda AO, Nurimoto S, Saichi N, Sakai H, Sanbonmatsu R, Shiba R, Suzuki M, Takabayashi K, Takahashi A, Tamura T, Tanaka M, Tanaka S, Todokoro F, Yamaguchi K, Yamamoto N, Okido T, Mashima J, Hashizume A, Jin L, Lee KB, Lin YC, Nozaki A, Sakai K, Tada M, Miyazaki S, Makino T, Ohyanagi H, Osato N, Tanaka N, Suzuki Y, Ikeo K, Saitou N, Sugawara H, O'Donovan C, Kulikova T, Whitfield E, Halligan B, Shimoyama M, Twigger S, Yura K, Kimura K, Yasuda T, Nishikawa T, Akiyama Y, Motono C, Mukai Y, Nagasaki H, Suwa M, Horton P, Kikuno R, Ohara O, Lancet D, Eveno E, Graudens E, Imbeaud S, Debily MA, Hayashizaki Y, Amid C, Han M, Osanger A, Endo T, Thomas MA, Hirakawa M, Makalowski W, Nakao M, Kim NS, Yoo HS, De Souza SJ, Bonaldo Mde F, Niimura Y, Kuryshev V, Schupp I, Wiemann S, Bellgard M, Shionyu M, Jia L, Thierry-Mieg D, Thierry-Mieg J, Wagner L, Zhang Q, Go M, Minoshima S, Ohtsubo M, Hanada K, Tonellato P, Isogai T, Zhang J, Lenhard B, Kim S, Chen Z, Hinz U, Estreicher A, Nakai K, Makalowska I, Hide W, Tiffin N, Wilming L, Chakraborty R, Soares MB, Chiusano ML, Auffray C, Yamaguchi-Kabata Y, Itoh T, Hishiki T, Fukuchi S, Nishikawa K, Sugano S, Nomura N, Tateno Y, Imanishi T, Gojobori T (2008) The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res 36: D793-799. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18089548

2007

  • Bechtel S, Rosenfelder H, Duda A, Schmidt CP, Ernst U, Wellenreuther R, Mehrle A, Schuster C, Bahr A, Blocker H, Heubner D, Hoerlein A, Michel G, Wedler H, Kohrer K, Ottenwalder B, Poustka A, Wiemann S, Schupp I (2007) The full-ORF clone resource of the German cDNA Consortium. BMC Genomics 8: 399. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17974005
  • Blackburn AC, Hill LZ, Roberts AL, Wang J, Aud D, Jung J, Nikolcheva T, Allard J, Peltz G, Otis CN, Cao QJ, Ricketts RS, Naber SP, Mollenhauer J, Poustka A, Malamud D, Jerry DJ (2007) Genetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer risk. Am J Pathol 170: 2030-2041. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17525270
  • Brueckner B, Stresemann C, Kuner R, Mund C, Musch T, Meister M, Sultmann H, Lyko F (2007) The Human let-7a-3 Locus Contains an Epigenetically Regulated MicroRNA Gene with Oncogenic Function. Cancer Res 67: 1419-1423. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17308078
  • Buness A, Kuner R, Ruschhaupt M, Poustka A, Sultmann H, Tresch A (2007) Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer. Bioinformatics 23: 2273-2280. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17599933
  • Conde AR, Martins AP, Brito M, Manuel A, Ramos S, Malta-Vacas J, Renner M, Poustka A, Mollenhauer J, Monteiro C (2007) DMBT1 is frequently downregulated in well-differentiated gastric carcinoma but more frequently upregulated across various gastric cancer types. Int J Oncol 30: 1441-1446. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17487364
  • Froehlich H, Fellmann M, Sueltmann H, Poustka A, Beissbarth T (2007) Large scale statistical inference of signaling pathways from RNAi and microarray data. BMC Bioinformatics 8: 386. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17937790
  • Frohlich H, Speer N, Poustka A, Beissbarth T (2007) GOSim--an R-package for computation of information theoretic GO similarities between terms and gene products. BMC Bioinformatics 8: 166. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17519018
  • Geldyyev A, Koleganova N, Piecha G, Sueltmann H, Finis K, Ruschaupt M, Poustka A, Gross ML, Berger I (2007) High expression level of bone degrading proteins as a possible inducer of osteolytic features in pigmented villonodular synovitis. Cancer Lett 255: 275-283. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17601661
  • Henrich KO, Claas A, Praml C, Benner A, Mollenhauer J, Poustka A, Schwab M, Westermann F (2007) Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma. Eur J Cancer 43: 607-616. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17222547
  • Kissling C, Retz W, Wiemann S, Coogan AN, Clement RM, Hunnerkopf R, Conner AC, Freitag CM, Rosler M, Thome J (2007) A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17948273
  • Klauck SM, Poustka F, Poustka A (2007) Autismus mit einem Spektrum an Verhaltensstörungen. Ursachenforschung zwischen Phänotyp und Genotyp im internationalen Netzwerk. GenomXPress 3: 19-22. Pubmed:
  • Kuner R, Vogt M, Sultmann H, Buness A, Dymalla S, Bulkescher J, Fellmann M, Butz K, Poustka A, Hoppe-Seyler F (2007) Identification of cellular targets for the human papillomavirus E6 and E7 oncogenes by RNA interference and transcriptome analyses. J Mol Med. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17589817
  • Laketa V, Simpson JC, Bechtel S, Wiemann S, Pepperkok R (2007) High-content microscopy identifies new neurite outgrowth regulators. Mol Biol Cell 18: 242-252. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17093056
  • Ligtenberg AJ, Veerman EC, Nieuw Amerongen AV, Mollenhauer J (2007) Salivary agglutinin/glycoprotein-340/DMBT1: a single molecule with variable composition and with different functions in infection, inflammation and cancer. Biol Chem 388: 1275-1289. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18020944
  • Loebke C, Sueltmann H, Schmidt C, Henjes F, Wiemann S, Poustka A, Korf U (2007) Infrared-based protein detection arrays for quantitative proteomics. Proteomics 7: 558-564. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17309101
  • Muller H, End C, Renner M, Helmke BM, Gassler N, Weiss C, Hartl D, Griese M, Hafner M, Poustka A, Mollenhauer J, Poeschl J (2007) Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant. Respir Res 8: 69. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17908325
  • Renner M, Bergmann G, Krebs I, End C, Lyer S, Hilberg F, Helmke B, Gassler N, Autschbach F, Bikker F, Strobel-Freidekind O, Gronert-Sum S, Benner A, Blaich S, Wittig R, Hudler M, Ligtenberg AJ, Madsen J, Holmskov U, Annese V, Latiano A, Schirmacher P, Amerongen AV, D'Amato M, Kioschis P, Hafner M, Poustka A, Mollenhauer J (2007) DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease. Gastroenterology 133: 1499-1509. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17983803
  • Rosenstiel P, Sina C, End C, Renner M, Lyer S, Till A, Hellmig S, Nikolaus S, Folsch UR, Helmke B, Autschbach F, Schirmacher P, Kioschis P, Hafner M, Poustka A, Mollenhauer J, Schreiber S (2007) Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion. J Immunol 178: 8203-8211. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17548659
  • Sahin O, Lobke C, Korf U, Appelhans H, Sultmann H, Poustka A, Wiemann S, Arlt D (2007) Combinatorial RNAi for quantitative protein network analysis. Proc Natl Acad Sci U S A 104: 6579-6584. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17420474
  • Sauermann M, Hahne F, Schmidt C, Majety M, Rosenfelder H, Bechtel S, Huber W, Poustka A, Arlt D, Wiemann S (2007) High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins. J Biomol Screen 12: 510-520. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17478479
  • Schlomm T, Sultmann H, Poustka A, Sauter G, Hellwinkel OJ, Huland H (2007) Molekulare Hochdurchsatzforschung beim Prostatakarzinom. Urologe A 46: 1097-1100. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17628772
  • Szatmari P, Paterson AD, Zwaigenbaum L, Roberts W, Brian J, Liu XQ, Vincent JB, Skaug JL, Thompson AP, Senman L, Feuk L, Qian C, Bryson SE, Jones MB, Marshall CR, Scherer SW, Vieland VJ, Bartlett C, Mangin LV, Goedken R, Segre A, Pericak-Vance MA, Cuccaro ML, Gilbert JR, Wright HH, Abramson RK, Betancur C, Bourgeron T, Gillberg C, Leboyer M, Buxbaum JD, Davis KL, Hollander E, Silverman JM, Hallmayer J, Lotspeich L, Sutcliffe JS, Haines JL, Folstein SE, Piven J, Wassink TH, Sheffield V, Geschwind DH, Bucan M, Brown WT, Cantor RM, Constantino JN, Gilliam TC, Herbert M, Lajonchere C, Ledbetter DH, Lese-Martin C, Miller J, Nelson S, Samango-Sprouse CA, Spence S, State M, Tanzi RE, Coon H, Dawson G, Devlin B, Estes A, Flodman P, Klei L, McMahon WM, Minshew N, Munson J, Korvatska E, Rodier PM, Schellenberg GD, Smith M, Spence MA, Stodgell C, Tepper PG, Wijsman EM, Yu CE, Roge B, Mantoulan C, Wittemeyer K, Poustka A, Felder B, Klauck SM, Schuster C, Poustka F, Bolte S, Feineis-Matthews S, Herbrecht E, Schmotzer G, Tsiantis J, Papanikolaou K, Maestrini E, Bacchelli E, Blasi F, Carone S, Toma C, Van Engeland H, de Jonge M, Kemner C, Koop F, Langemeijer M, Hijmans C, Staal WG, Baird G, Bolton PF, Rutter ML, Weisblatt E, Green J, Aldred C, Wilkinson JA, Pickles A, Le Couteur A, Berney T, McConachie H, Bailey AJ, Francis K, Honeyman G, Hutchinson A, Parr JR, Wallace S, Monaco AP, Barnby G, Kobayashi K, Lamb JA, Sousa I, Sykes N, Cook EH, Guter SJ, Leventhal BL, Salt J, Lord C, Corsello C, Hus V, Weeks DE, Volkmar F, Tauber M, Fombonne E, Shih A, Meyer KJ (2007) Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet 39: 319-328. Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17322880
  • Tresch A, Beissbarth T, Sultmann H, Kuner R, Poustka A, Buness A (2007) Discrimination of direct and indirect interactions in a network of regulatory effects. J Comput Biol 14: 1217-1228. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17990974

2006

  • Arlt D, Sahin O, Korf U, Loebke C, Beissbarth T, Hahne F, Wiemann S, Poustka A (2006) Modeling breast cell cycle regulation - overcoming drug resistance. Conf Proc IEEE Eng Med Biol Soc 1: 40-43. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17946776
  • Barth AS, Kuner R, Buness A, Ruschhaupt M, Merk S, Zwermann L, Kaab S, Kreuzer E, Steinbeck G, Mansmann U, Poustka A, Nabauer M, Sultmann H (2006) Identification of a common gene expression signature in dilated cardiomyopathy across independent microarray studies. J Am Coll Cardiol 48: 1610-1617. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17045896
  • Blasi F, Bacchelli E, Carone S, Toma C, Monaco AP, Bailey AJ, Maestrini E (2006a) SLC25A12 and CMYA3 gene variants are not associated with autism in the IMGSAC multiplex family sample. Eur J Hum Genet 14: 123-126. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16205742
  • Blasi F, Bacchelli E, Pesaresi G, Carone S, Bailey AJ, Maestrini E (2006b) Absence of coding mutations in the X-linked genes neuroligin 3 and neuroligin 4 in individuals with autism from the IMGSAC collection. Am J Med Genet B Neuropsychiatr Genet 141: 220-221. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16508939
  • del Val C, Kuryshev VY, Glatting KH, Ernst P, Hotz-Wagenblatt A, Poustka A, Suhai S, Wiemann S (2006) CAFTAN: a tool for fast mapping, and quality assessment of cDNAs. BMC Bioinformatics 7: 473. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17064411
  • Finis K, Sultmann H, Ruschhaupt M, Buness A, Helmchen B, Kuner R, Gross ML, Fink B, Schirmacher P, Poustka A, Berger I (2006) Analysis of pigmented villonodular synovitis with genome-wide complementary DNA microarray and tissue array technology reveals insight into potential novel therapeutic approaches. Arthritis Rheum 54: 1009-1019. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16508983
  • Fleischer S, Wiemann S, Will H, Hofmann TG (2006) PML-associated repressor of transcription (PAROT), a novel KRAB-zinc finger repressor, is regulated through association with PML nuclear bodies. Exp Cell Res 312: 901-912. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16412420
  • Gassler N, Newrzella D, Bohm C, Lyer S, Li L, Sorgenfrei O, van Laer L, Sido B, Mollenhauer J, Poustka A, Schirmacher P, Gretz N (2006) Molecular characterisation of non-absorptive and absorptive enterocytes in human small intestine. Gut 55: 1084-1089. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16556670
  • Haase B, Humphray SJ, Lyer S, Renner M, Poustka A, Mollenhauer J, Leeb T (2006) Molecular characterization of the porcine deleted in malignant brain tumors 1 gene (DMBT1). Gene 376: 184-191. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16624504
  • Hahne F, Arlt D, Sauermann M, Majety M, Poustka A, Wiemann S, Huber W (2006) Statistical methods and software for the analysis of high throughput reverse genetic assays using flow cytometry readouts. Genome Biol 7: R77. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16916453
  • Klauck S, Poustka A (2006) Animal models of autism. Drug Discovery Today: Disease Models 3: 313-318. Pubmed: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B75D8-4MMFVTG-1&_user=100035&_coverDate=02%2F28%2F2007&_rdoc=3&_fmt=summary&_orig=browse&_srch=doc-info(%23toc%2313032%232006%23999969995%23643617%23FLA%23display%23Volume)&_cdi=13032&_sort=d&_docanchor=&_ct=18&_acct=C000007318&_version=1&_urlVersion=0&_userid=100035&md5=b09408cfd32b97c3bd7c927bcf09a59b
  • Klauck SM (2006) Genetics of autism spectrum disorder. Eur J Hum Genet 14: 714-720. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16721407
  • Klauck SM, Felder B, Kolb-Kokocinski A, Schuster C, Chiocchetti A, Schupp I, Wellenreuther R, Schmotzer G, Poustka F, Breitenbach-Koller L, Poustka A (2006) Mutations in the ribosomal protein gene RPL10 suggest a novel modulating disease mechanism for autism. Mol Psychiatry 11: 1073-1084. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16940977
  • Kolb-Kokocinski A, Mehrle A, Bechtel S, Simpson A, Kioschis P, Wiemann S, Wellenreuther R, Poustka A (2006) The systematic functional characterisation of Xq28 genes prioritises candidate disease genes. BMC Genomics 7: 29. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16503986&query_hl=3&itool=pubmed_docsum
  • Kuryshev VY, Vorobyov E, Zink D, Schmitz J, Rozhdestvensky TS, Munstermann E, Ernst U, Wellenreuther R, Moosmayer P, Bechtel S, Schupp I, Horst J, Korn B, Poustka A, Wiemann S (2006) An anthropoid-specific segmental duplication on human chromosome 1q22. Genomics 88: 143-151. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16545939
  • Mehrle A, Rosenfelder H, Schupp I, Del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (2006) The LIFEdb database in 2006. Nucleic Acids Res 34: D415-418. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16381901
  • Orchard S, Apweiler R, Barkovich R, Field D, Garavelli JS, Horn D, Jones A, Jones P, Julian R, McNally R, Nerothin J, Paton N, Pizarro A, Seymour S, Taylor C, Wiemann S, Hermjakob H (2006) Proteomics and Beyond: a report on the 3rd Annual Spring Workshop of the HUPO-PSI 21-23 April 2006, San Francisco, CA, USA. Proteomics 6: 4439-4443. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16897683
  • Schneider J, Ruschhaupt M, Buness A, Asslaber M, Regitnig P, Zatloukal K, Schippinger W, Ploner F, Poustka A, Sultmann H (2006) Identification and meta-analysis of a small gene expression signature for the diagnosis of estrogen receptor status in invasive ductal breast cancer. Int J Cancer 119: 2974-2979. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17019712
  • Seiler M, Mehrle A, Poustka A, Wiemann S (2006) The 3of5 web application for complex and comprehensive pattern matching in protein sequences. BMC Bioinformatics 7: 144. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16542452
  • Sultmann H, Poustka A (2006) [Microarrays for the identification of molecular markers in the diagnosis and therapy of renal cell carcinomas.]. Urologe A 45: 297-304. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16465525
  • Takeda J, Suzuki Y, Nakao M, Barrero RA, Koyanagi KO, Jin L, Motono C, Hata H, Isogai T, Nagai K, Otsuki T, Kuryshev V, Shionyu M, Yura K, Go M, Thierry-Mieg J, Thierry-Mieg D, Wiemann S, Nomura N, Sugano S, Gojobori T, Imanishi T (2006) Large-scale identification and characterization of alternative splicing variants of human gene transcripts using 56,419 completely sequenced and manually annotated full-length cDNAs. Nucleic Acids Res 34: 3917-3928. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16914452
  • Treutlein J, Kissling C, Frank J, Wiemann S, Dong L, Depner M, Saam C, Lascorz J, Soyka M, Preuss UW, Rujescu D, Skowronek MH, Rietschel M, Spanagel R, Heinz A, Laucht M, Mann K, Schumann G (2006) Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples. Mol Psychiatry 11: 594-602. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16550213

2005

  • Arlt D, Huber W, Liebel U, Schmidt C, Majety M, Sauermann M, Rosenfelder H, Bechtel S, Mehrle A, Bannasch D, Schupp I, Seiler M, Simpson JC, Hahne F, Moosmayer P, Ruschhaupt M, Guilleaume B, Wellenreuther R, Pepperkok R, Sultmann H, Poustka A, Wiemann S (2005) Functional Profiling: From Microarrays via Cell-Based Assays to Novel Tumor Relevant Modulators of the Cell Cycle. Cancer Res 65: 7733-7742. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16140941
  • Bonora E, Lamb JA, Barnby G, Sykes N, Moberly T, Beyer KS, Klauck SM, Poustka F, Bacchelli E, Blasi F, Maestrini E, Battaglia A, Haracopos D, Pedersen L, Isager T, Eriksen G, Viskum B, Sorensen EU, Brondum-Nielsen K, Cotterill R, Engeland H, Jonge M, Kemner C, Steggehuis K, Scherpenisse M, Rutter M, Bolton PF, Parr JR, Poustka A, Bailey AJ, Monaco AP (2005) Mutation screening and association analysis of six candidate genes for autism on chromosome 7q. Eur J Hum Genet 13: 198-207. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15523497
  • Buness A, Huber W, Steiner K, Sultmann H, Poustka A (2005) arrayMagic: two-colour cDNA microarray quality control and preprocessing. Bioinformatics 21: 554-556. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15454413
  • End C, Lyer S, Renner M, Stahl C, Ditzer J, Holloschi A, Kuhn HM, Flammann HT, Poustka A, Hafner M, Mollenhauer J, Kioschis P (2005) Generation of a vector system facilitating cloning of DMBT1 variants and recombinant expression of functional full-length DMBT1. Protein Expr Purif 41: 275-286. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15866713
  • Guilleaume B, Buness A, Schmidt C, Klimek F, Moldenhauer G, Huber W, Arlt D, Korf U, Wiemann S, Poustka A (2005) Systematic comparison of surface coatings for protein microarrays. Proteomics 5: 4705-4712. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16267812
  • Hawtin P, Hardern I, Wittig R, Mollenhauer J, Poustka A, Salowsky R, Wulff T, Rizzo C, Wilson B (2005) Utility of lab-on-a-chip technology for high-throughput nucleic acid and protein analysis. Electrophoresis 26: 3674-3681. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16136523
  • Karenko L, Hahtola S, Paivinen S, Karhu R, Syrja S, Kahkonen M, Nedoszytko B, Kytola S, Zhou Y, Blazevic V, Pesonen M, Nevala H, Nupponen N, Sihto H, Krebs I, Poustka A, Roszkiewicz J, Saksela K, Peterson P, Visakorpi T, Ranki A (2005) Primary cutaneous T-cell lymphomas show a deletion or translocation affecting NAV3, the human UNC-53 homologue. Cancer Res 65: 8101-8110. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16166283
  • Korf U, Kohl T, van der Zandt H, Zahn R, Schleeger S, Ueberle B, Wandschneider S, Bechtel S, Schnolzer M, Ottleben H, Wiemann S, Poustka A (2005) Large-scale protein expression for proteome research. Proteomics. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16127724
  • Korf U, Wiemann S (2005) Protein microarrays as a discovery tool for studying protein-protein interactions. Expert Rev Proteomics 2: 13-26. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15966849
  • Michaelovsky E, Frisch A, Leor S, Stein D, Danziger Y, Carel C, Fennig S, Mimouni M, Klauck SM, Benner A, Poustka A, Apter A, Weizman A (2005) Haplotype analysis of the COMT-ARVCF gene region in Israeli anorexia nervosa family trios. Am J Med Genet B Neuropsychiatr Genet. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16118784
  • Neubrand VE, Will RD, Mobius W, Poustka A, Wiemann S, Schu P, Dotti CG, Pepperkok R, Simpson AJ (2005) gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking. EMBO Journal 24: 1122-1133. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15775984
  • Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RI, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Glockner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl P, Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, Muller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell C N, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J, Bentley DR (2005) The DNA sequence of the human X chromosome. Nature 434: 325-337. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15772651
  • Schlomm T, Luebke AM, Sultmann H, Hellwinkel OJ, Sauer U, Poustka A, David KA, Chun FK, Haese A, Graefen M, Erbersdobler A, Huland H (2005) Extraction and processing of high quality RNA from impalpable and macroscopically invisible prostate cancer for microarray gene expression analysis. Int J Oncol 27: 713-720. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16077921
  • Sultmann H, von Heydebreck A, Huber W, Kuner R, Buness A, Vogt M, Gunawan B, Vingron M, Fuzesi L, Poustka A (2005) Gene expression in kidney cancer is associated with cytogenetic abnormalities, metastasis formation, and patient survival. Clin Cancer Res 11: 646-655. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15701852
  • Wiemann S, Kolb-Kokocinski A, Poustka A (2005) Alternative pre-mRNA processing regulates cell-type specific expression of the IL4l1 and NUP62 genes. BMC Biol 3: 16. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16029492
  • Wittig R, Salowsky R, Blaich S, Lyer S, Maa JS, Muller O, Mollenhauer J, Poustka A (2005) Multiplex reverse transcription-polymerase chain reaction combined with on-chip electrophoresis as a rapid screening tool for candidate gene sets. Electrophoresis 26: 1687-1691. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15812845

2004

  • Bannasch D, Mehrle A, Glatting KH, Pepperkok R, Poustka A, Wiemann S (2004) LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system. Nucleic Acids Res 32 Database issue: D505-508. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14681468
  • Bikker FJ, Ligtenberg AJ, End C, Renner M, Blaich S, Lyer S, Wittig R, Van 't Hof W, Veerman EC, Nazmi K, De Blieck-Hogervorst JM, Kioschis P, Nieuw Amerongen AV, Poustka A, Mollenhauer J (2004a) Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains. J Biol Chem. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15355985
  • Bikker FJ, Van Der Wal JE, Ligtenberg AJ, Mollenhauer J, De Blieck-Hogervorst JM, Van Der Waal I, Poustka A, Nieuw Amerongen AV (2004b) Salivary Agglutinin/DMBT1(SAG) Expression is Up-regulated in the Presence of Salivary Gland Tumors. J Dent Res 83: 567-571. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15218048
  • Braidotti P, Nuciforo PG, Mollenhauer J, Poustka A, Pellegrini C, Moro A, Bulfamante G, Coggi G, Bosari S, Pietra GG (2004) DMBT1 expression is down-regulated in breast cancer. BMC Cancer 4: 46. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15301691
  • D'Adamo P, Bacchelli E, Blasi F, Lipp HP, Toniolo D, Maestrini E, (IMGSAC) atMGSoAC (2004) DNA variants in the human RAB3A gene are not associated with autism. Genes Brain Behav 3: 123-124. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15005721
  • del Val C, Mehrle A, Falkenhahn M, Seiler M, Glatting KH, Poustka A, Suhai S, Wiemann S (2004) High-throughput protein analysis integrating bioinformatics and experimental assays. Nucleic Acids Res 32: 742-748. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14762202
  • Gassler N, Kopitz J, Tehrani A, Ottenwalder B, Schnolzer M, Kartenbeck J, Lyer S, Autschbach F, Poustka A, Otto HF, Mollenhauer J (2004) Expression of acyl-CoA synthetase 5 reflects the state of villus architecture in human small intestine. J Pathol 202: 188-196. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14743501
  • Haller F, Kulle B, Schwager S, Gunawan B, von Heydebreck A, Sultmann H, Fuzesi L (2004) Equivalence test in quantitative reverse transcription polymerase chain reaction: confirmation of reference genes suitable for normalization. Anal Biochem 335: 1-9. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15519565
  • Helmke BM, Mollenhauer J, Herold-Mende C, Benner A, Thome M, Gassler N, Wahl W, Lyer S, Poustka A, Otto HF, Deichmann M (2004) BRAF mutations distinguish anorectal from cutaneous melanoma at the molecular level. Gastroenterology 127: 1815-1820. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15578519
  • Huber W, Gentleman R (2004) matchprobes: a Bioconductor package for the sequence-matching of microarray probe elements. Bioinformatics 20: 1651-1652. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14988118
  • Imanishi T, Itoh T, Suzuki Y, O'Donovan C, Fukuchi S, Koyanagi KO, Barrero RA, Tamura T, Yamaguchi-Kabata Y, Tanino M, Yura K, Miyazaki S, Ikeo K, Homma K, Kasprzyk A, Nishikawa T, Hirakawa M, Thierry-Mieg J, Thierry-Mieg D, Ashurst J, Jia L, Nakao M, Thomas MA, Mulder N, Karavidopoulou Y, Jin L, Kim S, Yasuda T, Lenhard B, Eveno E, Yamasaki C, Takeda J, Gough C, Hilton P, Fujii Y, Sakai H, Tanaka S, Amid C, Bellgard M, Bonaldo Md Mde F, Bono H, Bromberg SK, Brookes AJ, Bruford E, Carninci P, Chelala C, Couillault C, Souza SJ, Debily MA, Devignes MD, Dubchak I, Endo T, Estreicher A, Eyras E, Fukami-Kobayashi K, G RG, Graudens E, Hahn Y, Han M, Han ZG, Hanada K, Hanaoka H, Harada E, Hashimoto K, Hinz U, Hirai M, Hishiki T, Hopkinson I, Imbeaud S, Inoko H, Kanapin A, Kaneko Y, Kasukawa T, Kelso J, Kersey P, Kikuno R, Kimura K, Korn B, Kuryshev V, Makalowska I, Makino T, Mano S, Mariage-Samson R, Mashima J, Matsuda H, Mewes HW, Minoshima S, Nagai K, Nagasaki H, Nagata N, Nigam R, Ogasawara O, Ohara O, Ohtsubo M, Okada N, Okido T, Oota S, Ota M, Ota T, Otsuki T, Piatier-Tonneau D, Poustka A, Ren SX, Saitou N, Sakai K, Sakamoto S, Sakate R, Schupp I, Servant F, Sherry S, Shiba R, Shimizu N, Shimoyama M, Simpson AJ, Soares B, Steward C, Suwa M, Suzuki M, Takahashi A, Tamiya G, Tanaka H, Taylor T, Terwilliger JD, Unneberg P, Veeramachaneni V, Watanabe S, Wilming L, Yasuda N, Yoo HS, Stodolsky M, Makalowski W, Go M, Nakai K, Takagi T, Kanehisa M, Sakaki Y, Quackenbush J, Okazaki Y, Hayashizaki Y, Hide W, Chakraborty R, Nishikawa K, Sugawara H, Tateno Y, Chen Z, Oishi M, Tonellato P, Apweiler R, Okubo K, Wagner L, Wiemann S, Strausberg RL, Isogai T, Auffray C, Nomura N, Gojobori T, Sugano S (2004) Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol 2: 856-875. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15103394
  • Kontou M, Will RD, Adelfalk C, Wittig R, Poustka A, Hirsch-Kauffmann M, Schweiger M (2004) Thioredoxin, a regulator of gene expression. Oncogene 23: 2146-2152. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14730345
  • Mollenhauer J, Helmke B, Medina D, Bergmann G, Gassler N, Muller H, Lyer S, Diedrichs L, Renner M, Wittig R, Blaich S, Hamann U, Madsen J, Holmskov U, Bikker F, Ligtenberg A, Carlen A, Olsson J, Otto HF, O'Malley B, Poustka A (2004) Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis. Genes Chromosomes Cancer 39: 185-194. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14732920
  • Poustka AJ, Kuhn A, Radosavljevic V, Wellenreuther R, Lehrach H, Panopoulou G (2004) On the origin of the chordate central nervous system: expression of onecut in the sea urchin embryo. Evol Dev 6: 227-236. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15230963
  • Ruschhaupt M, Huber W, Poustka A, Mansmann U (2004) A Compendium to Ensure Computational Reproducibility in High-Dimensional Classification Tasks. Statistical Applications in Genetics and Molecular Biology 3: Article 37. Pubmed: http://www.bepress.com/sagmb/vol3/iss1/art37
  • Sasaki M, Tsuneyama K, Saito T, Kataoka H, Mollenhauer J, Poustka A, Nakanuma Y (2004) Site-characteristic expression and induction of trefoil factor family 1, 2 and 3 and malignant brain tumor-1 in normal and diseased intrahepatic bile ducts relates to biliary pathophysiology. Liver Int 24: 29-37. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15101998
  • Schneider J, Buness A, Huber W, Volz J, Kioschis P, Hafner M, Poustka A, Sultmann H (2004) Systematic analysis of T7 RNA polymerase based in vitro linear RNA amplification for use in microarray experiments. BMC Genomics 5: 29. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15119961
  • Starkuviene V, Liebel U, Simpson JC, Erfle H, Poustka A, Wiemann S, Pepperkok R (2004) High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic. Genome Res 14: 1948-1956. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15466293
  • Sultmann H, Poustka A (2004) Recent advances in transcription profiling of human cancer. Curr Opin Mol Ther 6: 593-599. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15663323
  • Wellenreuther R, Schupp I, Consortium TGc, Poustka A, Wiemann S (2004) SMART amplification combined with cDNA size fractionation in order to obtain large full-length clones. BMC Genomics 5: 36. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15198809
  • Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sultmann H, Poustka A (2004) From ORFeome to Biology: A Functional Genomics Pipeline. Genome Res 14: 2136-2144. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15489336

2003

  • Apic G, Huber W, Teichmann SA (2003) Multi-domain protein families and domain pairs: comparison with known structures and a random model of domain recombination. J Struct Funct Genom 4: 67-78. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14649290&dopt=Abstract
  • Bacchelli E, Blasi F, Biondolillo M, Lamb JA, Bonora E, Barnby G, Parr J, Beyer KS, Klauck SM, Poustka A, Bailey A, Monaco AP, Maestrini E, IMGSAC (2003) Screening of nine candidate genes for autism on chromosome 2q reveals rare non-sysnonymous variants in the cAMP-GEFII gene. Mol Psychiatry 8: 916 -924. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14593429&dopt=Abstract
  • Bonora E, Beyer KS, Lamb JA, Parr JR, Klauck SM, Benner A, Paolucci M, Abbot A, Ragoussis I, Poustka A, Bailey A, Monaco AP, IMGSAC (2003) Analysis of reelin as a candidate gene for autism. Mol Psychiatry 8: 885-892. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14515139&dopt=Abstract
  • Broders O, Breitling F, Dubel S (2003) Hyperphage. Improving antibody presentation in phage display. Methods Mol Biol 205: 295-302. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12491895
  • Gunawan B, von Heydebreck A, Huber W, Vingron M, Füzesi L (2003) Cytogenetic and Morphologic Typing of 58 Papillary Renal Cell Carcinomas: Evidence for a Cytogeneitc Evolution of Type 2 from Type 1 Tumors. Cancer Res 63: 6200-6205. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14559804&dopt=Abstract
  • Heiss NS, Poustka A (2003) Dyskeratosis Congenita. In: Chromosomal instability and aging: basic science and clinical implication. Pubmed:
  • Huber W, von Heydebreck A, Sultmann H, Poustka A, Vingron M (2003a) Parameter estimation for the calibration and variance stabilization of microarray data. Stat Appl Genet Mol Biol 2: Article 3. Pubmed:
  • Huber W, von Heydebreck A, Vingron M (2003b) Analysis of microarray gene expression data. In: Handbook of Statistical Genetics: 162-187. Pubmed:
  • Langer C, Gunawan B, Schuler P, Huber W, Füzesi L, Becker H (2003) Prognostic factors influencing surgical management and outcome of gastrointestinal stromal tumors. Br J Surg 90: 332-339. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12594669&dopt=Abstract
  • Liebel U, Starkuviene V, Erfle H, Simpson JC, Poustka A, Wiemann S, Pepperkok R (2003) A microscope-based screening platform for large-scale functional protein analysis in intact cells. FEBS Lett 554: 394-398. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14623100&dopt=Abstract
  • Madsen J, Tornoe I, Nielsen O, Lausen M, Krebs I, Mollenhauer J, Kollender G, Poustka A, Skjodt K, Holmskov U (2003) CRP-ductin, the mouse homologue of gp-340/deleted in malignant brain tumors 1 (DMBT1), binds gram-positive and gram-negative bacteria and interacts with lung surfactant protein D. Eur J Immunol 33: 2327-2336. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12884308
  • Mollenhauer J, Deichmann M, Helmke B, Muller H, Kollender G, Holmskov U, Ligtenberg T, Krebs I, Wiemann S, Bantel-Schaal U, Madsen J, Bikker F, Klauck SM, Otto HF, Moldenhauer G, Poustka A (2003) Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer. Int J Cancer 105: 149-157. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12673672
  • Sasaki M, Huang SF, Chen MF, Jan YY, Yeh TS, Ishikawa A, Mollenhauer J, Poustka A, Tsuneyama K, Nimura Y, Oda K, Nakanuma Y (2003a) Decrease of deleted in malignant brain tumour-1 (DMBT-1) expression is a crucial late event in intrahepatic cholangiocarcinoma. Histopathology 43: 340-346. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14511252&dopt=Abstract
  • Sasaki M, Huang SF, Chen MF, Jan YY, Yeh TS, Ishikawa A, Mollenhauer J, Poustka A, Tsuneyama K, Nimura Y, Oda K, Nakanuma Y (2003b) Expression of deleted in malignant brain tumor-1 (DMBT1) molecule in biliary epithelium is augmented in hepatolithiasis: possible participation in lithogenesis. Dig Dis Sci 48: 1234-1240. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12870778
  • Schumann G, Rujescu D, Kissling C, Soyka M, Dahmen N, Preuss UW, Wiemann S, Müller A, Wellek S, Lascorz J, Bondy B, Giegling I, Anghelescu I, Cowen MS, Poustka A, Spanagel R, Mann K, Henn FA, Szegedi A (2003a) Analysis of genetic variations of Protein Tyrosine Kinase fyn and their as-sociation with alcohol dependence in two independent cohorts. Biol Psychiatry 54: 1422-1426. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14675807&dopt=Abstract
  • Schumann G, Rujescu D, Szegedi A, Singer P, Wiemann S, Wellek S, Giegling I, Klawe C, Anghelescu I, Heinz A, Spanagel R, Mann K, Henn FA, Dahmen N (2003b) No association of alcohol dependence with a NMDA-receptor 2B gene variant. Mol Psychiatry 8: 11-12. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12556902
  • Straub BK, Boda J, Kuhn C, Schnoelzer M, Korf U, Kempf T, Spring H, Hatzfeld M, Franke WW (2003) A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells. J Cell Sci 116: 4985-4995. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14625392&dopt=Abstract
  • Wellenreuther R, Bechtel S (2003) Identifying transcribed sequences and beyond. Genome Biol 4: 306. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12620115
  • Wiemann S, Bechtel S, Bannasch D, Pepperkok R, Poustka A, Network TGc (2003a) The German cDNA Network: cDNAs, functional genomics and proteomics. J Struct Funct Genom 4: 87-96. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14649292&dopt=Abstract
  • Wiemann S, Mehrle A, Bechtel S, Wellenreuther R, Pepperkok R, Poustka A, Consortium TGc (2003b) cDNAs in functional genomics and proteomics: The German cDNA Consortium. CRBiologies 326: 1003-1009. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14744107&dopt=Abstract

2002

  • Aradhya S, Woffendin H, Bonnen P, Heiss NS, Yamagata T, Esposito T, Bardaro T, Poustka A, D'Urso M, Kenwrick S, Nelson DL (2002) Physical and genetic characterization reveals a pseudogene, an evolutionary junction, and unstable loci in distal Xq28. Genomics 79: 31-40. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11827455
  • Beyer KS, Blasi F, Bacchelli E, Klauck SM, Maestrini E, Poustka A (2002a) Mutation analysis of the coding sequence of the MECP2 gene in infantile autism. Hum Genet 111: 305-309. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12384770
  • Beyer KS, Klauck SM, Benner A, Poustka F, Poustka A (2002b) Association studies of the HOPA dodecamer duplication variant in different subtypes of autism. Am J Med Genet 114: 110-115. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11840515
  • Bikker FJ, Ligtenberg AJ, Nazmi K, Veerman EC, van't Hof W, Bolscher JG, Poustka A, Nieuw Amerongen AV, Mollenhauer J (2002) Identification of the bacteria-binding peptide domain on salivary agglutinin (gp-340/DMBT1), a member of the scavenger receptor cysteine-rich superfamily. J Biol Chem 277: 32109-32115. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12050164
  • Bonora E, Bacchelli E, Levy RE, Blasi F, Marlow A, Monaco AP, Maestrini E, IMGSAC (2002) Mutation screening and imprinting analysis of four candidate genes for autism in the 7q32 region. Mol Psychiatry 7: 289-301. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11920156&dopt=Abstract
  • Copley LM, Zhao WD, Kopacz K, Herman GE, Kioschis P, Poustka A, Taudien S, Platzer M (2002) Exclusion of mutations in the MTMR1 gene as a frequent cause of X-linked myotubular myopathy. Am J Med Genet 107: 256-258. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11807911
  • Coy JF, Wiemann S, Bechmann I, Bachner D, Nitsch R, Kretz O, Christiansen H, Poustka A (2002) Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. Gene 290: 73-94. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12062803
  • Deichmann M, Mollenhauer J, Helmke B, Thome M, Hartschuh W, Poustka A, Naher H (2002) Analysis of losses of heterozygosity of the candidate tumour suppressor gene DMBT1 in melanoma resection specimens. Oncology 63: 166-172. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12239452
  • Heiss NS, Poustka A, Gene) DD (2002) DKC1 Gene. In: Creighton T, Ed, editor. In: Encyclopedia of Molecular Medicine. Publisher: John Wiley & Sons Inc. New York. pp. 1121 - 1126.
  • Huber W, Boer JM, von Heydebreck A, Gunawan B, Vingron M, Fuzesi L, Poustka A, Sultmann H (2002a) Transcription profiling of renal cell carcinoma. Verh Dtsch Ges Pathol 86: 153-164. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12647365
  • Huber W, Von Heydebreck A, Sultmann H, Poustka A, Vingron M (2002b) Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 18 Suppl 1: S96-S104. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12169536
  • Klauck SM, Lindsay S, Beyer KS, Splitt M, Burn J, Poustka A (2002) A mutation hot spot for nonspecific X-linked mental retardation in the MECP2 gene causes the PPM-X syndrome. Am J Hum Genet 70: 1034-1037. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11885030
  • Mollenhauer J, Helmke B, Muller H, Kollender G, Krebs I, Wiemann S, Holmskov U, Madsen J, Otto HF, Poustka A (2002a) An integrative model on the role of DMBT1 in epithelial cancer. Cancer Detect Prev 26: 266-274. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12430631
  • Mollenhauer J, Helmke B, Muller H, Kollender G, Lyer S, Diedrichs L, Holmskov U, Ligtenberg T, Herbertz S, Krebs I, Wiemann S, Madsen J, Bikker F, Schmitt L, Otto HF, Poustka A (2002b) Sequential changes of the DMBT1 expression and location in normal lung tissue and lung carcinomas. Genes Chromosomes Cancer 35: 164-169. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12203780
  • Mollenhauer J, Muller H, Kollender G, Lyer S, Diedrichs L, Helmke B, Holmskov U, Ligtenberg T, Herbertz S, Krebs I, Madsen J, Bikker F, Schmitt L, Wiemann S, Scheurlen W, Otto HF, von Deimling A, Poustka A (2002c) The SRCR/SID region of DMBT1 defines a complex multi-allele system representing the major basis for its variability in cancer. Genes Chromosomes Cancer 35: 242-255. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12353266
  • Mueller W, Mollenhauer J, Stockhammer F, Poustka A, von Deimling A (2002) Rare mutations of the DMBT1 gene in human astrocytic gliomas. Oncogene 21: 5956-5959. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12185598
  • Newbury DF, Bonora E, Lamb JA, Fisher SE, Lai C, Baird G, Jannoun L, Solonims V, Stott CM, Merricks J, Bolton P F, A.J. B, Monaco AP, IMGSAC (2002) FOXP2 is not a major susceptibility gene for autism or specific language impairment. Am J Hum Genet 70: 1318-1327. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11894222&dopt=Abstract
  • Poland J, Sinha P, Siegert A, Schnolzer M, Korf U, Hauptmann S (2002) Comparison of protein expression profiles between monolayer and spheroid cell culture of HT-29 cells revealed fragmentation of CK18 in three-dimensional cell culture. Electrophoresis 23: 1174-1184. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11981867&dopt=Abstract
  • Salowsky R, Heiss NS, Benner A, Wittig R, Poustka A (2002) Basal transcription activity of the dyskeratosis congenita gene is mediated by Sp1 and Sp3 and a patient mutation in a Sp1 binding site is associated with decreased promoter activity. Gene 293: 9-19. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12137939
  • Schumann G, D. R, Szegedi A, Singer P, Wiemann S, Welek S, Giegling I, C. K, I. A, Heinz A, Spanagel R, Mann K, Henn FA, Dahmen N (2002) Alcohol dependence is associated with NMDN receptor 2B gene variant. Eur Psychiatry 17: 212. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12556902&dopt=Abstract
  • von Heydebreck A, Huber W, Poustka A, Vingron M (2002) Variance stabilization and robust normalization for microarray gene expression data. Proceeding in Computational Statistics: 623-628. Pubmed:
  • Wittig R, Nessling M, Will RD, Mollenhauer J, Salowsky R, Munstermann E, Schick M, Helmbach H, Gschwendt B, Korn B, Kioschis P, Lichter P, Schadendorf D, Poustka A (2002) Candidate genes for cross-resistance against DNA-damaging drugs. Cancer Res 62: 6698-6705. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12438269

2001

  • (IMGSAC) IMGSoAC, Palfermann S, Matthews N, Turner M, Moore J, Haervas A, Aubin A, Wallace S, Michelotti J, Wainhouse D, Paul A, Thompson E, Murin M, Gupta R, Garner C, Pickles A, Rutter M, Bailey A, Lamb JA, Marlow A, Scudder P, Barnby G, Monaco AP, Baird G, Cox A, Docherty Z, Warburton P, Green ED, Abbs SJ, Le Couteur A, McConachie HR, Klauck SM, Beyer KS, Epp S, Poustka A, Brenner A, al. e (2001) Further characterization of the autism susceptibility locus AUTS 1 on chromosome 7q. Hum Mol Genet 10: 973-982. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11392322&dopt=Abstract
  • Beyer KS, Klauck SM, Wiemann S, Poustka A (2001) Construction of a physical map of an autism susceptibility region in 7q32.3-q33. Gene 272: 85-91. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11470513
  • Boer JM, Huber WK, Sultmann H, Wilmer F, von Heydebreck A, Haas S, Korn B, Gunawan B, Vente A, Fuzesi L, Vingron M, Poustka A (2001) Identification and classification of differentially expressed genes in renal cell carcinoma by expression profiling on a global human 31,500-element cDNA array. Genome Res 11: 1861-1870. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11691851
  • Gotte K, Riedel F, Neubuer J, Schafer C, Coy J, Hormann K (2001) The relationship between allelic imbalance on 17p, p53 overexpression in head and neck cancer. Int J Oncology 19: 331-336. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11445847&dopt=Abstract
  • Gunawan B, Huber W, Holtrup M, von Heydebreck A, Efferth T, Poustka A, Ringert RH, Jakse G, Fuzesi L (2001) Prognostic impacts of cytogenetic findings in clear cell renal cell carcinoma: gain of 5q31-qter predicts a distinct clinical phenotype with favorable prognosis. Cancer Res 61: 7731-7738. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11691785
  • Heiss NS, Megarbane A, Klauck SM, Kreuz FR, Makhoul E, Majewski F, Poustka A (2001) One novel and two recurrent missense DKC1 mutations in patients with dyskeratosis congenita (DKC). Genet Couns 12: 129-136. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11491307
  • Hoff C, Mollenhauer J, Waldau B, Hamann U, Poustka A (2001) Allelic imbalance and fine mapping of the 17p13.3 subregion in sporadic breast carcinomas. Cancer Genet Cytogenet 129: 145-149. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11566345
  • Huber W, von Heydebreck A, Sültmann H, Poustka A, Vingron M (2001) Data preprocessing and quality control for DNA array expression profiling experiments. In: Mabrouk NE, Lengauer T, Sankoff D, Eds, editors. In: Currents in Computational Molecular Biology. Publisher: Les Publications CRM Montreal. pp. 181-182.
  • International Molecular Genetic Study of Autism Consortium (IMGSAC), Palfermann S, Matthews N, Turner M, J. M, Hervas A, Aubin A, S. W, Michelotti J, Wainhouse D, Paul A, Thompson E, Gupta R, Garner C, Murin M, Freitag C, Ryder N, Cottington E, Parr J, Pickles A, Rutter M, Bailey A, Barnby G, Lamb JA, Marlow A, Scudder P, Monaco AP, Baird G, Cox A, Docherty Z, Warburton P, S.M. K, Beyer KS, Epp S, Poustka A, Brenner A, al. e (2001) A genome wide screen for autism: Strong evidence for linkage to chromosomes 2q, 7q and 16p. Am J Hum Genet 69: 570-581. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11481586&dopt=Abstract
  • McPherson JD, Marra M, Hillier L, Waterston RH, Chinwalla A, Wallis J, Sekhon M, Wylie K, Mardis ER, Wilson RK, Fulton R, Kucaba TA, Wagner-McPherson C, Barbazuk WB, Gregory SG, Humphray SJ, French L, Evans RS, Bethel G, Whittaker A, Holden JL, McCann OT, Dunham A, Soderlund C, Scott CE, Bentley DR, Schuler G, Chen HC, Jang W, Green ED, Idol JR, Maduro VV, Montgomery KT, Lee E, Miller A, Emerling S, Kucherlapati, Gibbs R, Scherer S, Gorrell JH, Sodergren E, Clerc-Blankenburg K, Tabor P, Naylor S, Garcia D, de Jong PJ, Catanese JJ, Nowak N, Osoegawa K, Qin S, Rowen L, Madan A, Dors M, Hood L, Trask B, Friedman C, Massa H, Cheung VG, Kirsch IR, Reid T, Yonescu R, Weissenbach J, Bruls T, Heilig R, Branscomb E, Olsen A, Doggett N, Cheng JF, Hawkins T, Myers RM, Shang J, Ramirez L, Schmutz J, Velasquez O, Dixon K, Stone NE, Cox DR, Haussler D, Kent WJ, Furey T, Rogic S, Kennedy S, Jones S, Rosenthal A, Wen G, Schilhabel M, Gloeckner G, Nyakatura G, Siebert R, Schlegelberger B, Korenberg J, Chen XN, Fujiyama A, Hattori M, Toyoda A, Yada T, Park HS, Sakaki Y, Shimizu N, Asakawa S, Kawasaki K, Sasaki T, Shintani A, Shimizu A, Shibuya K, Kudoh J, Minoshima S, Ramser J, Seranski P, Hoff C, Poustka A, Reinhardt R, Lehrach H (2001) A physical map of the human genome. Nature 409: 934-941. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11237014
  • Mollenhauer J, Herbertz S, Helmke B, Kollender G, Krebs I, Madsen J, Holmskov U, Sorger K, Schmitt L, Wiemann S, Otto HF, Grone HJ, Poustka A (2001) Deleted in Malignant Brain Tumors 1 is a versatile mucin-like molecule likely to play a differential role in digestive tract cancer. Cancer Res 61: 8880-8886. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11751412
  • Nadeau JH, Balling R, Barsh G, Beier D, Brown SD, Bucan M, Camper S, Carlson G, Copeland N, Eppig J, Fletcher C, Frankel WN, Ganten D, Goldowitz D, Goodnow C, Guenet JL, Hicks G, de Angelis MH, Jackson I, Jacob HJ, Jenkins N, Johnson D, Justice M, Kay S, Kingsley D, Lehrach H, Magnuson T, Meisler M, Poustka A, Rinchik EM, Rossant J, Russell LB, Schimenti J, Shiroishi T, Skarnes WC, Soriano P, Stanford W, Takahashi JS, Wurst W, Zimmer A (2001) Sequence interpretation. Functional annotation of mouse genome sequences. Science 291: 1251-1255. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11233449
  • Pepperkok R, Simpson JC, Wiemann S (2001) Being in the right location at the right time. Genome Biol 2: REVIEWS1024. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11574061
  • Rondot S, Koch J, Breitling F, Dubel S (2001) A helper phage to improve single-chain antibody presentation in phage display. Nat Biotechnol 19: 75-78. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11135557
  • Seranski P, Hoff C, Radelof U, Hennig S, Reinhardt R, Schwartz CE, Heiss NS, Poustka A (2001) RAI1 is a novel polyglutamine encoding gene that is deleted in Smith-Magenis syndrome patients. Gene 270: 69-76. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11404004
  • Simpson JC, Neubrand VE, Wiemann S, Pepperkok R (2001) Illuminating the human genome. Histochem Cell Biol 115: 23-29. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11219604
  • von Heydebreck A, Huber W, Poustka A, Vingron M (2001) Identifying splits with clear separation: a new class discovery method for gene expression data. Bioinformatics 17 Suppl 1: S107-114. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11472999
  • Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (2001) Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. Genome Res 11: 422-435. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11230166
  • Wirth J, Back E, Hüttenhofer A, Nothwang HG, Lich C, Groß S, Menzel CS, A., Kioschis P, Tommerup N, Ropers HH, Horsthemke B, Buiting K (2001) A transcriptional breakpoint cluster disrupts the newly defined 3' end of the SNURF-SNRPN transcription unit on chromosome 15. Hum Mol Genet 10: 201-210. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11159938&dopt=Abstract

2000

  • Aradhya S, Ahobila P, Lewis RA, Nelson DL, Esposito T, Ciccodicola A, Bardaro T, D'Urso M, Woffendin H, Kenwrick S, Smahi A, Heuertz S, Munnich A, Heiss NS, Poustka A, Chishti AH (2000a) Filamin (FLN1), plexin (SEX), major palmitoylated protein p55 (MPP1), and von-Hippel Lindau binding protein (VBP1) are not involved in incontinentia pigmenti type 2. Am J Med Genet 94: 79-84. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10982489
  • Aradhya S, Nelson DL, Heiss NS, Poustka A, Woffendin H, Kenwrick S, Esposito T, Ciccodicola A, Bardaro T, D'Urso M, Smahi A, Munnich A, Herman GE, Lewis RA (2000b) Human homologue of the murine bare patches/striated gene is not mutated in incontinentia pigmenti type 2. Am J Med Genet 91: 241-244. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10756353
  • Beissbarth T, Fellenberg K, Brors B, Arribas-Prat R, Boer J, Hauser NC, Scheideler M, Hoheisel JD, Schutz G, Poustka A, Vingron M (2000) Processing and quality control of DNA array hybridization data. Bioinformatics 16: 1014-1022. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11159313
  • Breitling F, Schmiedl A, Winter CH, Queitsch I, Dübel S (2000) Effect of engineered cysteines on yield, solubility and activity in various recombinant antibody formats expressed in E. coli. Protein Eng 13: 725-734. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11112512&dopt=Abstract
  • Briault S, Villard L, Rogner U, Coy J, Odent S, Lucas J, Passage E, Zhu D, Shrimpton A, Pembrey M, Till M, Guichet A, Dessay S, Fontes M, Poustka A, Moraine C (2000) Mapping of X chromosome inversion breakpoints [inv(X)(q11q28)] associated with FG syndrome: a second FG locus [FGS2]? Am J Med Genet 95: 178-181. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11078572
  • Finzer P, Soto U, Delius H, Patzelt A, Coy JF, Poustka A, zur Hausen H, Rosl F (2000) Differential transcriptional regulation of the monocyte-chemoattractant protein-1 (MCP-1) gene in tumorigenic and non-tumorigenic HPV 18 positive cells: the role of the chromatin structure and AP-1 composition. Oncogene 19: 3235-3244. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10918580
  • Heiss NS, Bachner D, Salowsky R, Kolb A, Kioschis P, Poustka A (2000) Gene structure and expression of the mouse dyskeratosis congenita gene, dkc1. Genomics 67: 153-163. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10903840
  • Hoff C, Seranski P, Mollenhauer J, Korn B, Detzel T, Reinhardt R, Ramser J, Poustka A (2000) Physical and transcriptional mapping of the 17p13.3 region that is frequently deleted in human cancer. Genomics 70: 26-33. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11087658
  • Koch J, Breitling F, Dubel S (2000) Rapid titration of multiple samples of filamentous bacteriophage (M13) on nitrocellulose filters. Biotechniques 29: 1196-1198, 2002. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11126120
  • Los M, Neubuser D, Coy JF, Mozoluk M, Poustka A, Schulze-Osthoff K (2000) Functional characterization of DNase X, a novel endonuclease expressed in muscle cells. Biochemistry 39: 7365-7373. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10858283
  • Mallon AM, Platzer M, Bate R, Gloeckner G, Botcherby MR, Nordsiek G, Strivens MA, Kioschis P, Dangel A, Cunningham D, Straw RN, Weston P, Gilbert M, Fernando S, Goodall K, Hunter G, Greystrong JS, Clarke D, Kimberley C, Goerdes M, Blechschmidt K, Rump A, Hinzmann B, Mundy CR, Miller W, Poustka A, Herman GE, Rhodes M, Denny P, Rosenthal A, Brown SD (2000) Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. Genome Res 10: 758-775. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10854409
  • Mollenhauer J, Herbertz S, Holmskov U, Tolnay M, Krebs I, Merlo A, Schroder HD, Maier D, Breitling F, Wiemann S, Grone HJ, Poustka A (2000) DMBT1 encodes a protein involved in the immune defense and in epithelial differentiation and is highly unstable in cancer. Cancer Res 60: 1704-1710. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10749143
  • Reichwald K, Thiesen J, Wiehe T, Weitzel J, Poustka A, Rosenthal A, Platzer M, Stratling WH, Kioschis P (2000) Comparative sequence analysis of the MECP2ßlocus in man and mouse reveals novel transcribed regions. Mamm Genome 11: 182-190. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10723722&dopt=Abstract
  • Schmiedl A, Breitling F, Dubel S (2000a) Expression of a bispecific dsFv-dsFv' antibody fragment in Escherichia coli. Protein Eng 13: 725-734. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11112512
  • Schmiedl A, Breitling F, Winter CH, Queitsch I, Dubel S (2000b) Effects of unpaired cysteines on yield, solubility and activity of different recombinant antibody constructs expressed in E. coli. J Immunol Methods 242: 101-114. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10986393
  • Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (2000) Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. EMBO Rep 1: 287-292. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11256614
  • Smahi A, Courtois G, Vabres P, Yamaoka S, Heuertz S, Munnich A, Israel A, Heiss NS, Klauck SM, Kioschis P, Wiemann S, Poustka A, Esposito T, Bardaro T, Gianfrancesco F, Ciccodicola A, D'Urso M, Woffendin H, Jakins T, Donnai D, Stewart H, Kenwrick SJ, Aradhya S, Yamagata T, Levy M, Lewis RA, Nelson DL (2000) Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium. Nature 405: 466-472. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10839543
  • Thullner S, Gesellchen F, Wiemann S, Pyerin W, Kinzel V, Bossemeyer D (2000) The protein kinase A catalytic subunit Cbeta2: molecular characterization and distribution of the splice variant. Biochem J 351: 123-132. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10998354
  • von Deimling A, Fimmers R, Schmidt MC, Bender B, Fassbender F, Nagel J, Jahnke R, Kaskel P, Duerr EM, Koopmann J, Maintz D, Steinbeck S, Wick W, Platten M, Muller DJ, Przkora R, Waha A, Blumcke B, Wellenreuther R, Meyer-Puttlitz B, Schmidt O, Mollenhauer J, Poustka A, Stangl AP, Lenartz D, von Ammon K (2000) Comprehensive allelotype and genetic anaysis of 466 human nervous system tumors. J Neuropathol Exp Neurol 59: 544-558. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10850867
  • Yaghmai R, Kimyai-Asadi A, Rostamiani K, Heiss NS, Poustka A, Eyaid W, Bodurtha J, Nousari HC, Hamosh A, Metzenberg A (2000) Overlap of dyskeratosis congenita with the Hoyeraal-Hreidarsson syndrome. J Pediatr 136: 390-393. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10700698

1999

  • Coy JF, Sedlacek Z, Bachner D, Delius H, Poustka A (1999) A complex pattern of evolutionary conservation and alternative polyadenylation within the long 3"-untranslated region of the methyl-CpG-binding protein 2 gene (MeCP2) suggests a regulatory role in gene expression. Hum Mol Genet 8: 1253-1262. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10369871
  • Eickhoff B, Korn B, Schick M, Poustka A, van der Bosch J (1999) Normalization of array hybridization experiments in differential gene expression analysis. Nucleic Acids Res 27: e33. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10536166
  • Heiss NS, Girod A, Salowsky R, Wiemann S, Pepperkok R, Poustka A (1999a) Dyskerin localizes to the nucleolus and its mislocalization is unlikely to play a role in the pathogenesis of dyskeratosis congenita. Hum Mol Genet 8: 2515-2524. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10556300
  • Heiss NS, Poustka A, Knight SW, Aradhya S, Nelson DL, Lewis RA, Esposito T, Ciccodicola A, D'Urso M, Smahi A, Heuertz S, Munnich A, Vabres P, Woffendin H, Kenwrick S (1999b) Mutation analysis of the DKC1 gene in incontinentia pigmenti. J Med Genet 36: 860-862. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10636732
  • Holmskov U, Mollenhauer J, Madsen J, Vitved L, Gronlund J, Tornoe I, Kliem A, Reid KB, Poustka A, Skjodt K (1999) Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D. Proc Natl Acad Sci U S A 96: 10794-10799. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10485905
  • Knight SW, Heiss NS, Vulliamy TJ, Aalfs CM, McMahon C, Richmond P, Jones A, Hennekam RC, Poustka A, Mason PJ, Dokal I (1999a) Unexplained aplastic anaemia, immunodeficiency, and cerebellar hypoplasia (Hoyeraal-Hreidarsson syndrome) due to mutations in the dyskeratosis congenita gene, DKC1. Br J Haematol 107: 335-339. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10583221
  • Knight SW, Heiss NS, Vulliamy TJ, Greschner S, Stavrides G, Pai GS, Lestringant G, Varma N, Mason PJ, Dokal I, Poustka A (1999b) X-linked dyskeratosis congenita is predominantly caused by missense mutations in the DKC1 gene. Am J Hum Genet 65: 50-58. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10364516
  • Maestrini E, Lai C, Marlow A, Matthews N, Wallace S, Bailey A, Cook EH, Weeks DE, Monaco AP, The international Molecular Genetic Study of Autism (IMGSA) Consortium (Klauck SMB, K.S.; Spieler, A.; Poustka, A.Ö Poustka, F.; Rühl, D.; Schmötzer, G.; Bölte, S.;) (1999) Serotonin transporter (5-HTT) and gamma-aminobutyric acid receptor subunit beta3 (GABRB3) gene polymorphisms are not associated with autism in the IMGSA families. Am J Hum Genet 88: 492-496. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10490705&dopt=Abstract
  • Mollenhauer J, Holmskov U, Wiemann S, Krebs I, Herbertz S, Madsen J, Kioschis P, Coy JF, Poustka A (1999) The genomic structure of the DMBT1 gene: evidence for a region with susceptibility to genomic instability. Oncogene 18: 6233-6240. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10597221
  • Monaghan AP, Kioschis P, Wu W, Zuniga A, Bock D, Poustka A, Delius H, Niehrs C (1999) Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev 87: 45-56. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10495270
  • Peters N, Waha A, Wellenreuther R, Friedrich RE, Mautner VF, Hoffmeyer S, Lenartz D, Schramm J, Wiestler OD, von Deimling A (1999) Quantitative analysis of NF1 and OMGP gene transcripts in sporadic gkiomas, sporadic meningiomas and neurofibromatiois type 1 - associated plexiform neurofibromas. Acta Neuropathol 97: 547-551. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10378372&dopt=Abstract
  • Scheurlen WG, Schwabe GC, Seranski P, Joos S, Harbott J, Metzke S, Dohner H, Poustka A, Wilgenbus K, Haas OA (1999) Mapping of the breakpoints on the short arm of chromosome 17 in neoplasms with an i(17q). Genes Chromosomes Cancer 25: 230-240. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10379869
  • Sedlacek Z, Munstermann E, Dhorne-Pollet S, Otto C, Bock D, Schutz G, Poustka A (1999a) Human and mouse XAP-5 and XAP-5-like (X5L) genes: identification of an ancient functional retroposon differentially expressed in testis. Genomics 61: 125-132. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10534398
  • Sedlacek Z, Shimeld SM, Munstermann E, Poustka A (1999b) The amphioxus rab GDP-dissociation inhibitor (GDI) gene is neural-specific: implications for the evolution of chordate rab GDI genes. Mol Biol Evol 16: 1231-1237. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10486978
  • Seranski P, Heiss NS, Dhorne-Pollet S, Radelof U, Korn B, Hennig S, Backes E, Schmidt S, Wiemann S, Schwarz CE, Lehrach H, Poustka A (1999) Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes. Genomics 56: 1-11. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10036180
  • Vente A, Korn B, Zehetner G, Poustka A, Lehrach H (1999) Distribution and early development of microarray technology in Europe. Nat Genet 22: 22. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10319856
  • von Deimling A, Larson J, Wellenreuther R, Stangl AP, van Velthoven V, Warnick R, Tew J, Balko G, Menon AG (1999) Clonal origin of recurrent meningiomas. Brain Pathol 9: 645-650. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10517503&dopt=Abstract
  • Vulliamy TJ, Knight SW, Heiss NS, Smith OP, Poustka A, Dokal I, Mason PJ (1999) Dyskeratosis congenita caused by a 3' deletion: germline and somatic mosaicism in a female carrier. Blood 94: 1254-1260. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10438713
  • Wolf S, Sharpe LT, Schmidt HJ, Knau H, Weitz S, Kioschis P, Poustka A, Zrenner E, Lichter P, Wissinger B (1999) Direct visual resolution of gene copy number in the human photopigment gene array. Invest Ophthalmol Vis Sci 40: 1585-1589. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10359341

1998

  • Dahamne N, Ghezala GA, Gosset P, Chamoun Z, Dufresne-Yacharia MC, Lopes C, Rabatel N, Gassanova-Maugenre S, Chettouh Z, Abramowski V, Fayet E, Yaspo ML, Korn B, Blouin JL, Lehrach H, Poustka A, Antonarakis SE, Sinet, P.M., Créau N, Delabar JM (1998) Transcriptional map of the 2.5 Mb CBR-ERG region of chromosome 21 involved in Down syndrome. Genomics 48: 12-23. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9503011&dopt=Abstract
  • Haas S, Vingron M, Poustka A, Wiemann S (1998) Primer design for large scale sequencing. Nucleic Acids Res 26: 3006-3012. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9611248
  • Heiss NS, Knight SW, Vulliamy TJ, Klauck SM, Wiemann S, Mason PJ, Poustka A, Dokal I (1998) X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions. Nat Genet 19: 32-38. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9590285
  • Kioschis P, Wiemann S, Heiss NS, Francis F, Gotz C, Poustka A, Taudien S, Platzer M, Wiehe T, Beckmann G, Weber J, Nordsiek G, Rosenthal A (1998) Genomic organization of a 225-kb region in Xq28 containing the gene for X-linked myotubular myopathy (MTM1) and a related gene (MTMR1). Genomics 54: 256-266. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9828128
  • Kischkel FC, Kioschis P, Weitz S, Poustka A, Lichter P, Krammer PH (1998) Assignment of CASP8 to human chromosome band 2q33-->q34 and Casp8 to the murine syntenic region on chromosome 1B-proximal C by in situ hybridization. Cytogenet Cell Genet 82: 95-96. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9763668
  • Klauck SM, Poustka A, Poustka F (1998) Genetik des Autismus. Med Genet 19: 409-411. Pubmed:
  • Knight SW, Vulliamy TJ, Heiss NS, Matthijs G, Devriendt K, Connor JM, D'Urso M, Poustka A, Mason PJ, Dokal I (1998) 1.4 Mb candidate gene region for X linked dyskeratosis congenita defined by combined haplotype and X chromosome inactivation analysis. J Med Genet 35: 993-996. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9863595
  • Milani N, Mülhardt C, Weber RG, Lichter P, Kioschis P, Poustka A, Becker CM (1998) The human glycine receptor b subunit gene (GLRB): structure, refined chromosomal localization and population polymorphism. Genomics 50: 341-345. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9676428&dopt=Abstract
  • Nikolic Z, Laube B, Weber RG, Lichter P, Kioschis P, Poustka A, Mulhardt C, Becker CM (1998) The human glycine receptor subunit a3: Structure of the GLRA3 gene, localization to the distal chromosome 4q, and functional characterization of alternative transcripts. J Biol Chem 273: 19708-19714. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9677400&dopt=Abstract
  • Radelof U, Hennig S, Seranski P, Steinfath M, Ramser J, Reinhardt R, Poustka A, Francis F, Lehrach H (1998) Preselection of shotgun clones by oligonucleotide fingerprinting: an efficient and high throughput strategy to reduce redundancy in large-scale sequencing projects. Nucleic Acids Res 26: 5358-5364. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9826759
  • Rondot S, Anthony KG, Dubel S, Ida N, Wiemann S, Beyreuther K, Frost LS, Little M, Breitling F (1998) Epitopes fused to F-pilin are incorporated into functional recombinant pili. J Mol Biol 279: 589-603. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9641980
  • Scheurlen W, Schwabe GC, Joos S, Mollenhauer J, Sorensen N, Kuhl J (1998) Molecular analysis of childhood primitive neuroectodermal tumours defines markers associated with poor outcome. J Clin Oncol 16: 2478-2485. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9667267&dopt=Abstract
  • Sedlacek Z, Kodet R, Poustka A, Goetz P (1998a) A database of germline p53 mutations in cancer-prone families. Nucleic Acids Res 26: 214-215. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9399838
  • Sedlacek Z, Kodet R, Seemanova E, Vodvarka P, Wilgenbus P, Mares J, Poustka A, Goetz P (1998b) Two Li-Fraumeni syndrome families with novel germline p53 mutations: loss of the wild-type p53 allele in only 50% of tumours. Br J Cancer 77: 1034-1039. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9569035
  • Sedlacek Z, Munstermann E, Mincheva A, Lichter P, Poustka A (1998c) The human rab GDI beta gene with long retroposon-rich introns maps to 10p15 and its pseudogene to 7p11-p13. Mamm Genome 9: 78-80. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9434952
  • The International Molecular Genetic Study of Autism Consortium (1998) A full genome screen for autism with evidence for linkage to a region on chromosome 7q. Hum Mol Genet 7: 571-578. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9546821&dopt=Abstract

1997

  • Albig W, Kioschis P, Poustka A, Meergans K, Doenecke D (1997) Human histone gene organisation: non-regular arrangement within a large cluster. Genomics 40: 314-322. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9119399&dopt=Abstract
  • Briault S, Hill R, Shrimpton A, Zhu D, Till M, Ronce N, Margaritte-Jeannin P, Baraitser M, Middleton-Price H, Malcolm S, Thompson E, Hoo J, Wilson G, Romano C, Guichet A, Pembrey M, Fontes M, Poustka A, Moraine C (1997) A gene for FG syndrome maps in the Xq12-q21.31 region. Am J Med Genet 73: 87-90. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9375929
  • Heiss NS, Gloeckner G, Bachner D, Kioschis P, Klauck SM, Hinzmann B, Rosenthal A, Herman GE, Poustka A (1997) Genomic structure of a novel LIM domain gene (ZNF185) in Xq28 and comparisons with the orthologous murine transcript. Genomics 43: 329-338. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9268636
  • Heiss NS, Poustka A (1997) Genomic structure of a novel chloride channel gene, CLIC2, in Xq28. Genomics 45: 224-228. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9339381
  • Klauck SM, Munstermann E, Bieber-Martig B, Ruhl D, Lisch S, Schmotzer G, Poustka A, Poustka F (1997a) Molecular genetic analysis of the FMR-1 gene in a large collection of autistic patients. Hum Genet 100: 224-229. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9254854
  • Klauck SM, Poustka F, Benner A, Lesch KP, Poustka A (1997b) Serotonin transporter (5-HTT) gene variants associated with autism? Hum Mol Genet 6: 2233-2238. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9361027
  • Laporte J, Kioschis P, Hu LJ, Kretz C, Carlsson B, Poustka A, Mandel JL, Dahl N (1997) Cloning and characterization of an alternatively spliced gene in proximal Xq28 deleted in two patients with intersexual genitalia and myotubular myopathy. Genomics 41: 458-462. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9169146
  • Lesch KP, Meyer J, Glatz K, Flugge G, Hinney A, Hebebrand J, Klauck SM, Poustka A, Poustka F, Bengel D, Mossner R, Riederer P, Heils A (1997) The 5-HT transporter gene-linked polymorphic region (5-HTTLPR) in evolutionary perspective: alternative biallelic variation in rhesus monkeys. Rapid communication. J Neural Transm 104: 1259-1266. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9503271
  • Mollenhauer J, Wiemann S, Scheurlen W, Korn B, Hayashi Y, Wilgenbus KK, von Deimling A, Poustka A (1997) DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours. Nat Genet 17: 32-39. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9288095
  • Scheurlen WG, Seranski P, Mincheva A, Kuhl J, Sorensen N, Krauss J, Lichter P, Poustka A, Wilgenbus KK (1997) High-resolution deletion mapping of chromosome arm 17p in childhood primitive neuroectodermal tumors reveals a common chromosomal disruption within the Smith-Magenis region, an unstable region in chromosome band 17p11.2. Genes Chromosomes Cancer 18: 50-58. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8993980
  • Seither P, Coy J, Poustka A, Grummt I (1997) Molecular cloning and characterisation of the cDNA encoding the largest subunit of mouse RNA polymerase I. Mol Gen Genet 255: 180-186. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9236775&dopt=Abstract
  • Wilgenbus K, Seranski P, Brown A, Leuchs B, Mincheva A, Lichter P, Poustka A (1997) Molecular characterisation of a genetically unstable region containing the SMSßcritical area and a breakpoint cluster for human PNET's. Genomics 42: 1-10. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9177769&dopt=Abstract
  • Wilke K, Gaul R, Klauck SM, Poustka A (1997a) A gene in human chromosome band Xq28 (GABRE) defines a putative new subunit class of the GABAA neurotransmitter receptor. Genomics 45: 1-10. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9339354
  • Wilke K, Wiemann S, Gaul R, Gong W, Poustka A (1997b) Isolation of human and mouse HMG2a cDNAs: evidence for an HMG2a-specific 3' untranslated region. Gene 198: 269-274. Pubmed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9370291

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