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Selected Publications
2011
Schaich M, Röllig C, Soucek S, Kramer M, Thiede C, Mohr B, Oelschlaegel U, Schmitz N, Stuhlmann R, Wandt H, Schäfer-Eckart K, Aulitzky W, Kaufmann M, Bodenstein H, Tischler J, Ho AD, Krämer A, Bornhäuser M, Schetelig J, Ehninger G, for the Study Alliance Leukemia (SAL): Cytarabine dose of 36 g/m² versus 12 g/m² within first consolidation in acute myeloid leukemia: Results of 933 patients enrolled in the prospective randomized AML96 study. Journal of Clinical Oncology (in press), 2011.
Dietrich S, Hegenbart U, Andrulis M, Schmitt T, Bellos F, Martens U, Meissner J, Krämer A, Ho AD, Dreger P: Blastic plasmacytoid dendritic cell neoplasia (BPDC) in elderly patients: Results of a treatment algorithm employing allogeneic stem cell transplantation with moderately reduced conditioning intensity. Biology of Blood and Marrow Transplantation (accepted for publication), 2011.
Sertel S, Fu Y, Zu Y, Rebacz B, Konkimalla B, Plinkert PK, Krämer A, Gertsch J, Efferth T: Molecular docking and pharmacogenomics of Vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochemical Pharmacology (accepted for publication), 2011.
Löffler H*, Fechter A*, Matuszewska M, Saffrich R, Mistrik M, Marhold J, Hornung C, Westermann F, Bartek J, Krämer A: Cep63 Recruits Cdk1 to the Centrosome: Implications for Regulation of Mitotic Entry, Centrosome Amplification and Genome Maintenance. Cancer Research 71: 2129-2139, 2011. *These authors contributed equally to this work.
Shahmoradgoli M, Mannherz O, Engel F, Heck S, Krämer A, Seiffert M, Pscherer A, Lichter P: Anti-apoptotic function of Charged Multivesicular Body Protein 5 (CHMP5), a potentially relevant gene in acute myeloid leukemia. International Journal of Cancer, Aug 23 (epub ahead of print), 2010.
2010
Stein S, Ott MG, Schultze-Strasser S, Jauch A, Burwinkel B, Kinner A, Schmidt M, Krämer A, Schwäble J, Glimm H, Koehl U, Preiss C, Ball C, Martin H, Göhring G, Schwarzwaelder K, Hofmann WK, Karakaya K, Tchatchou S, Yang R, Reinecke P, Kühlcke K, Schlegelberger B, Thrasher AJ, Hoelzer D, Seger R, von Kalle C, Grez M. Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease. Nature Medicine 16: 198-204, 2010.
Leber B, Maier B, Fuchs F, Chi J, Riffel P, Anderhub S, Wagner L, Ho AD, Salisbury JL, Boutros M, Krämer A: Proteins required for centrosome clustering in cancer cells. Science Translational Medicine 26: 33ra38, 2010.
Sellner L, Capper D, Meyer J, Langhans C-D, Hartog C-M, Pfeifer H, Serve H, Ho AD, Okun JG*, Krämer A*, von Deimling A*: Increased levels of 2-hydroxyglutarate in AML patients with IDH1-R132H and IDH2-R140Q mutations. European Journal Haematology 2010. *shared corresponding authorship.
2009
Hose D, Moreaux J, Meißner T, Seckinger A, Lewis J, Benesch V, Benner A, Hundemer M, Hielscher T, Shaughnessy JD Jr., Barlogie B, Neben K, Krämer A, Reme T, Hillengass J, Bertsch U, Jauch A, De Vos J, Rossi JF, Möhler T, Blake J, Zimmermann J, Klein B, Goldschmidt H: Inhibition of aurora kinases as option for risk adapted tailored treatment in multiple myeloma. Blood 113: 4331-4340, 2009.
2008
Fabarius A, Giehl M, Rebacz B, Krämer A, Frank O, Haferlach C, Duesberg P, Hehlmann R, Seifarth W, Hochhaus A: Centrosome aberrations and G1 phase arrest after in vitro and in vivo treatment with the SRC/ABL inhibitor dasatinib. Haematologica 93: 1145-1154, 2008.
2007
Neben K, Ott G, Schweizer S, Kalla J, Tews B, Katzenberger T, Hahn M, Rosenwald A, Ho AD, Müller-Hermelink HK, Lichter P, Krämer A. Expression of centrosome-associated gene products is linked to tetraploidization in mantle cell lymphoma. Int J Cancer. 2007 Apr 15;120(8):1669-77.
2005
Bartkova J, Horejsi Z, Koed K, Krämer A, Tort F, Zieger K, Guldberg P, Sehested M, Nesland J, Lukas C, Ørntoft T, Lukas J, Bartek J: DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434: 864-870, 2005.
2004
Leo E, Scheuer L, Kerowgan M, Schmitt C, Leo A, Baumbach T, Parwaresch R, Krämer A, Ho AD: Severe thrombocytopenia associated with a combination of rituximab, fludarabine and cyclophosphamide in the treatment of relapsed follicular lymphoma. European Journal of Hematology 73: 251-257, 2004.
