Hasskarl, J., Butz, K., Whitaker, N., Ullmann, A., and Hoppe-Seyler, F. 2000.
Differential cell cycle response of non-tumorigenic and tumorigenic HPV-positive keratinocytes towards TGFbeta1.
J. Mol. Med., 78: 94-101.

Butz, K., Denk, C., Ullmann, A., Scheffner, M., and Hoppe-Seyler, F. 2000.
Induction of apoptosis in human papillomavirus-positive cancer cells by peptide aptamers targeting the viral E6 oncoprotein.
Proc. Natl. Acad. Sci. USA, 97: 6693-6697.

Hoppe-Seyler, F. and Butz, K. 2000.
Peptide aptamers: powerful new tools for molecular medicine.
J. Mol. Med., 78: 426-430.

Hoppe-Seyler, F., and Butz K. 2001.
Viral mechanisms of human carcinogenesis.
In: The Molecular Basis of Human Cancer (eds. W. B. Coleman, G. J. Tsongalies), The Humana Press Inc., Totowa, New Jersey, 2001: 233-247.

Denk, C., Butz, K., Schneider, A., Dürst, M., and F. Hoppe-Seyler. 2001.
p53 mutations are rare events in recurrent cervical cancer.
J. Mol. Med., 79: 283-288.

Beger, M., Butz K., Denk, C., Williams, T., Hurst, H. C., and F. Hoppe-Seyler. 2001.
Expression pattern of AP-2 transcription factors in cervical cancer cells and analysis of their influence on human papillomavirus oncogene transcription.
J. Mol. Med., 79: 314-320.

Hoppe-Seyler, F., Crnković-Mertens, I., Denk, C., Fitscher, B., Klevenz, B., Tomai, E., and Butz, K. 2001.
Peptide aptamers: new molecules to study protein interactions.
J. Steroid Biochem. Mol. Biol., 78: 105-111.

Butz, K., Denk, C., Fitscher, B., Crnković-Mertens, I., Ulmann, A., Schröder, C. H., and Hoppe-Seyler, F. 2001.
Peptide aptamers targeting the hepatitis B virus core protein: a new generation of molecules with antiviral activity.
Oncogene, 20: 6579-6586.

Klevenz, B., Butz, K., and Hoppe-Seyler, F. 2002.
Peptide aptamers: exchange of the thioredoxin-A scaffold by alternative platform proteins and its influence on target protein binding.
Cell. Mol. Life Sci., 59: 1993-1998.

Crnković-Mertens, I., Hoppe-Seyler, F., and Butz, K. 2003.
Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene.
Oncogene, 22: 8330-8336.

Bürger, C, Nagel-Wolfrum, K., Kunz, C., Wittig, I., Butz, K., Hoppe-Seyler, F., and Groner, B. 2003.
Sequence-specific peptide aptamers, which interact with the intracellular domain of the epidermal growth factor receptor, interfere with Stat3 activation and inhibit the growth of tumor cells.
J. Biol. Chem., 278: 37610-37621.

Butz, K., Ristriani, T., Hengstermann, A., Denk, C., Scheffner, M., and Hoppe-Seyler, F. 2003.
siRNA-targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells.
Oncogene, 22: 5938-5945.

Hoppe-Seyler, F., Crnković-Mertens, I., Tomai, E., and Butz, K. 2004.
Peptide aptamers: specific inhibitors of protein function.
Curr. Mol. Med., 4: 529-538.

Hoppe-Seyler, F. 2004.
Novel therapeutic perspectives: The targeted inhibition of genes and proteins.
Curr. Mol. Med., 4: i-ii.

Nagel-Wolfrum, K., Buerger, C., Wittig, I., Butz, K., Hoppe-Seyler, F., and Groner, B. 2004.
The interaction of specific peptide aptamers with the DNA binding domain and the dimerisation domain of the transcription factor Stat3 inhibits transactivation and induces apoptosis in tumor cells.
Mol. Cancer Res., 2: 170-182.

Hengstermann, A., D’silva, D.A., Kuballa, P., Butz, K., Hoppe-Seyler, F., and Scheffner, M. 2005.
Apoptosis induced by downregulation of E6-AP expression in HPV-positive cancer cell lines depends on p53.
J. Virol., 79: 9296-9300.

Crnković-Mertens, I., Semzow, J., Hoppe-Seyler, F., and Butz, K. 2006.
Isoform-specific silencing of the livin gene by RNA interference defines Livin β as key mediator of apoptosis inhibition in HeLa cells.
J. Mol. Med., 84: 232-240.

Vogt, M., Butz, K., Dymalla, S., Semzow, J., and Hoppe-Seyler, F. 2006.
Inhibition of bax activity is crucial for the anti-apoptotic function of the human papillomavirus E6 oncoprotein.
Oncogene, 25: 4009-4015.

Tomai, E., Butz, K., Lohrey, C., von Weizsäcker, F., Zentgraf, H., and Hoppe- Seyler, F. 2006.
Peptide aptamer-mediated inhibition of target proteins by sequestration into aggresomes.
J. Biol. Chem., 281: 21345-21352

Crnkovic-Mertens, I., Muley, T., Meister, M., Hartenstein, B., Semzow, J., Butz, K., and Hoppe-Seyler, F. 2006.
The anti-apoptotic livin gene is an important determinant for the apoptotic resistance of non-small cell lung cancer cells.
Lung Cancer, 54: 135-142.

Crnkovic-Mertens, I., Wagener, N., Semzow, J., Gröne, E.F., Haferkamp, A., Hohenfellner, M., Butz, K., and Hoppe-Seyler, F. 2007.
Targeted inhibition of Livin resensitizes renal cancer cells towards apoptosis.
Cell. Mol. Life Sci., 64: 1137-1144.

Kuner, R., Vogt, M., Sültmann, H., Buness, A., Dymalla, S., Bulkescher, J., Fellmann, M., Butz, K., Poustka, A., and Hoppe-Seyler, F. 2007.
Identification of cellular targets for the human papillomavirus E6 and E7 oncogenes by RNA interference and transcriptome analyses.
J. Mol. Med. 85: 1253-1262.

Wagener, N., Crnkovic-Mertens, I., Vetter, C., Macher-Göppinger, S., Bedke, J., Gröne, E.F., Zentgraf, H., Pritsch, M., Butz, K., Buse, S., Haferkamp, A., Autschbach, F., Hohenfellner, M., and Hoppe-Seyler, F. 2007.
Expression of inhibitor of apoptosis protein (IAP) Livin in renal cell carcinoma and non-tumorous adult kidney.
Br. J. Cancer 97: 1271-1276.

Amon-Omer, A., Levin, A., Hayouka, Z., Butz, K., Hoppe-Seyler, F., Loya, S., Hizi, A., Friedler, A., and Loyter, A. 2008.
Correlation between shiftide activity and HIV-1 integrase inhibition by a peptide selected from a combinatorial library.
J. Mol. Biol., 376: 971-982

Hoppe-Seyler, F., Dymalla, S., Moosmeier, M. A., and Hoppe-Seyler, K. 2008.
Induction of Apoptosis by Peptide Aptamers Targeting the Viral E6 Oncoprotein
In: Peptides as Drugs - Discovery and Development (ed. B. Groner). Wiley-VCH, in press

Wagener, N., Holland, D., Bulkescher, J., Crnković-Mertens, I., Hoppe-Seyler, K., Zentgraf, H., Pritsch, M., Buss, S., Pfitzenmaier, J., Haferkamp, A., Hohenfellner, M., and Hoppe-Seyler, F. 2008.
The enhancer of zeste homolog 2 (EZH2) gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells
Int. J. Cancer 123: 1545-1550.

Haferkamp, A., Bedke, J., Vetter, C., Pritsch, M., Wagener, N., Buse, S., Crnkovic-Mertens, I., Hoppe-Seyler, K., Macher-Göppinger, S., Hoppe-Seyler, F., Autschbach, F., and Hohenfellner, M. 2008.
Expression of the inhibitor of apoptosis protein Livin in renal cell carcinoma and its prognostic implication.
Br. J. Urol. Int., 102: 1700-1706

Holland, D., Maroldt, J., Dürst, M., Hoppe-Seyler, K., Hoppe-Seyler, F. 2008.
Activation of the Enhancer of Zeste Homolog-2 Gene by the Human Papillomavirus E7 Oncoprotein.
Cancer Res. 68: 9964-9972.

Hoppe-Seyler, K., Weigand, K., Hoppe-Seyler, F., Sauer, P. 2009.
Cellular growth inhibition by FK778 is linked to G1 arrest or S phase sccumulation, depending on the functional status of the retinoblastoma protein.
Int. J. Mol. Med., 23:415-420

Dymalla, S., Scheffner, M., Weber, E., Sehr, P., Lohrey, C., Hoppe-Seyler, F., Hoppe-Seyler, K. 2009.
A novel peptide motif binding to and blocking the intracellular activity of the human papillomavirus E6 oncoprotein
J. Mol. Med., 87: 3121-331

Cullmann, C., Hoppe-Seyler, K., Dymalla, S., Lohrey, C., Scheffner, M., Dürst, M., Hoppe-Seyler, F. 2009.
Oncogenic human papillomaviruses block expression of the B-cell translocation gene-2 (BTG2) tumor suppressor gene.
Int. J. Cancer 125: 2014-2020.

Moosmeier, M. A., Bulkescher, J., Hoppe-Seyler, K., Hoppe-Seyler, F. 2010.
Binding proteins internalized by PTD-fused ligands allow the intracellular sequestration of selected targets by ligand exchange.
Int. J. Mol. Med., 25:557-564.

Moosmeier, M. A., Bulkescher, J., Reed, J., Schnölzer, M., Heid, H., Hoppe-Seyler, K., Hoppe-Seyler, F. 2010.
Transtactin: a universal transmembrane delivery system for Strep-tag II-fused cargos.
J. Cell. Mol. Med., 14:1935-1945.

Mern, D. S., Hoppe-Seyler, K., Hoppe-Seyler, F., Hasskarl, J., Burwinkel, B. 2010.
Targeting Id1 and Id3 by a specific peptide aptamer induces E-box promoter activity, cell cycle arrest, and apoptosis in breast cancer cells.
Breast Cancer Res. Treat., 124: 623-633.

Crnkovic-Mertens, I., Bulkescher, J., Mensger, N., Hoppe-Seyler, F., Hoppe-Seyler, K. 2010.
Isolation of peptides blocking the function of the anti-apoptotic Livin protein.
Cell. Mol. Life Sci., 67:1895-1905.

Wagener, N., Macher-Goeppinger, S., Pritsch, M., Hüsing, J., Hoppe-Seyler, K., Schirmacher, P., Pfitzenmaier, J., Haferkamp, A., Hoppe-Seyler, F., Hohenfellner, F. 2010.
Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma.
BMC Cancer, 10: 524.

Laurenson, S., Pett, M. R., Hoppe-Seyler, K., Denk, C., Hoppe-Seyler, F., Coleman, N., Ko Ferrigno, P. 2011.
Development of peptide aptamer microarrays for detection of HPV16 oncoproteins in cell extracts.
Anal. Biochem. 410: 161-170.

Hoppe-Seyler, F. Hoppe-Seyler, K. 2011.
Emerging topics in tumor virology.
Int. J. Cancer 129: 1289-1299.

Fussbroich, B., Wagener, N., Macher-Goeppinger, S., Benner, A., Fälth, M., Sültmann. H., Holzer, A., Hoppe-Seyler, K., and Hoppe-Seyler, F. 2011
EZH2 depletion blocks the proliferation of colon cancer cells.
PLoS ONE 6: 6(7):e21651.

Hoppe-Seyler, K., Sauer, P., Lohrey, C., Hoppe-Seyler, F. 2012
The inhibitors of nucleotide biosynthesis leflunomide, FK778, and mycophenolic acid activate hepatitis B virus replication in vitro.
Hepatology, 56: 9-16.

Wagener, N., Bulkescher, J., Macher-Goeppinger, S., Karapanagiotou-Schenkel, I., Hatiboglu, G., Abdel-Rahim, M., Abol-Enein, H., Ghoneim, M.A., Bastian, P.J., Müller, S.C., Haferkamp, A., Hohenfellner, M., Hoppe-Seyler, F., Hoppe-Seyler. K. 2013.
Endogenous BTG2 expression stimulates migration of bladder cancer cells and correlates with poor clinical prognosis for bladder cancer patients.
Br. J. Cancer, in press.

Honegger, A., Leitz, J., Bulkescher, J., Hoppe-Seyler, K. and Hoppe-Seyler, F. 2013.
Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and amounts of extracellular microvesicles released from HPV-positive cancer cells.
Int. J. Cancer, in press.