PD Dr. Stefan Wiemann

© dkfz.de

To an increasing extent, biomedical research is progressing from focusing on a small number of molecules or cellular events to global functional analysis and systems observations. With this course of action, whole genome or proteome analysis are often needed to study fundamental processes in cancer. The idea is to identify all molecules in a system in order to explain how it functions and to gain insight into a global view of mechanisms of disease development and progression, and to understand the processes distorted in disease and their potential cure.
These changes in the investigative approach result in a need for modified central services, some of which require high throughput technologies.
The core facilities at DKFZ are undergoing a restructuring and consolidating phase to adopt the new requirements and to provide high quality, up-to-date service. The focus is upon steadily improving service offers and the establishment of novel technologies to enable investigators to address the scientific questions in cancer. In order to answer the needs of DKFZ groups, we are very interested in learning about services and technologies you would like to see implemented in the GPCF, either in the form of full service availability or as assisted access to technologies and instruments.
In addition, the GPCF provide training in key methods for students and in-house staff.
We are happy to supply you with more information or to discuss technical matters concerning your research project.

Many different services are integrated within the individual groups listed above. The Microarray Unit provides expression profiling of mRNA and miRNA, Genotyping , genome-wide methylation analysis , next generation sequencing and a clone and vector repository .
Moreover, you may find an opportunities to test your cultured cells for potential contaminants: contamination control , or to book central GPCF equipment like Real Time PCR machine, sample preparation robot or SilverQuant scanning system. Finally, the wetlab wiki system (ww@DKFZ) allows you to share and discuss protocols with your colleagues at DKFZ.