Original- und Übersichtsarbeiten im Jahr 2020 und im Druck

Balavarca Y, Weigl K, Thomsen H, Brenner H.
Performance of individual and joint risk stratification by an environmental risk score and a genetic risk score in a colorectal cancer screening setting.
International Journal of Cancer 2020; 146:627-634.

McNabb S, Harrison TA, Albanes D, Berndt SI, Brenner H,…, Hoffmeister M,…, Wolk A, Woods MO, Phipps AI, Peters U.
Meta-analysis of 16 studies of the association of alcohol with colorectal cancer.
International Journal of Cancer 2020; 146:861-873.

Hilvo M, Meikle PJ, Pedersen ER, Tell GS, Dhar I, Brenner H, Schöttker B, Lääperi M, Kauhanen D, Koistinen KM, Jylhä A, Huynh K, Mellett NA, Tonkin AM, Sullivan DR, Simes J, Nestel P, Koenig W, Rothenbacher D, Nygard O, Laaksonen R.
Development and validation of ceramide and phospholipid based cardiovascular risk estimation score for coronary artery disease patients.
European Heart Journal 2020; 41:371-380.

Gào X, Wilsgaard T, Jansen EHJM, Yang X, Anusruti A, Brenner H, Schöttker B.
Serum total thiol levels and the risk of lung, colorectal, breast and prostate cancer: A prospective case-cohort study.
International Journal of Cancer 2020; 146:1261-1267.

Boakye D, Walter V, Jansen L, Martens U, Chang-Claude J, Hoffmeister M, Brenner H.
Magnitude of the age advancement effect of comorbidites in colorectal cancer prognosis.
Journal of the National Comprehensive Cancer Network 2020; 18:59-68.

Stocker H, Nabers A, Perna L, Möllers T, Rujescu D, Hartmann A, Holleczek B, Schöttker B, Gerwert K, Brenner H.
Prediction of Alzheimer’s disease diagnosis within 14 years through Aβ misfolding in blood plasma compared to APOE4 status, and other risk factors.
Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 2020; 16:283-291.

Cornish AJ, Law PJ, Timofeeva M, Palin K, Farrington SM, Palles C, Jenkins MA, Casey G, Brenner H, Chang-Claude J, Hoffmeister M, Kirac I, Maughan T, Brezina S, Gsur A, Cheadle JP, Aaltonen LA, Tomlinson I, Dunlop MG, Houlston RS.
Modifiable pathways for colorectal cancer: a Mendelian randomisation analysis.
The Lancet Gastroenterology & Hepatology 2020; 5:55-62.

Niersmann C, Carstensen-Kirberg M, Maalmi H, Holleczek B, Roden M, Brenner H, Herder C, Schöttker B.
Higher circulating omentin is associated with increased risk of primary cardiovascular events in individuals with diabetes.
Diabetologia 2020; 63:410-418.

Guan Z, Raut JR, Weigl K, Schöttker B, Holleczek B, Zhang Y, Brenner H.
Individual and joint performance of DNA methylation profiles, genetic risk scores and environmental risk scores for predicting breast cancer risk.
Molecular Oncology 2020; 14:42-53.

Mukama T, Fallah M, Tian Y, Sundquist K, Sundquist J, Brenner H, Kharazmi E.
Risk-tailored starting age of breast cancer screening based on women’s reproductive profile: nationwide cohort study.
European Journal of Cancer 2020; 124:207-213.

Niedermaier T, Balavarca Y, Brenner H.
Stage specific sensitivity of fecal immunochemical tests for detecting colorectal cancer: systematic review and meta-analysis.
American Journal of Gastroenterology 2020; 115:56-69.

Möllers T, Perna L, Stocker H, Ihle P, Schubert I, Schöttker B, Frölich L, Bauer J, Brenner H.
Alzheimer’s disease medication and outcomes of hospitalization among patients with dementia.
Epidemiology and Psychiatric Sciences 2020; 29:e73, 1-9.

Bhardwaj M, Weigl K, Tikk K, Benner A, Schrotz-King P, Brenner H.
Multiplex screening of 275 plasma protein biomarkers for identifying a signature for early detection of colorectal cancer.
Molecular Oncology 2020; 14:8-21.

Gies A, Niedermaier T, Weigl K, Schrotz-King P, Hoffmeister M, Brenner H.
Effect of long-term frozen storage and thawing of stool samples on faecal haemoglobin concentration and diagnostic performance of faecal immunochemical tests.
Clinical Chemistry and Laboratory Medicine 2020; 58:390-398.

Schöttker B, Xuan Y, Gào X, Anusruti A, Brenner H.
Oxidatively damaged DNA/RNA and 8-isoprostane levels are associated with the development of type 2 diabetes mellitus at older age: results from a large cohort study.
Diabetes Care 2020; 43:130-136.

Bielska-Lasota M, Rossi S, Krzyzak M, Haelens A, Domenic A, De Angelis R, Maciejczyk A, Rodriguez-Barranco M, Zadnik V, Minicozzi P, EUROCARE-5 Working Group*.
Reasons for low cervical cancer survival in new accession European Union countries: a EUROCARE-5 study.
Archives of Gynecology and Obstetrics 2020; 301:591-602.
*Collaborator from DKFZ: Brenner H

Fachal L, Aschard H, Beesley J, Barnes DR, Allen J,..., Brenner H,..., Schöttker B,..., Simard J, Easton DF, Kraft P, Dunning AM.
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.
Nature Genetics 2020; 52:56-73.

Barahona Ponce C, Scherer D, Boekstegers F, Garate-Calderon V, Jenab M, Aleksandrova K, Katzke V, Weiderpass E, Bonet C, Moradi T, Fischer K, Bossers W, Brenner H, Schöttker B, Holleczek B, Hveem K, Eklund N, Völker U, Waldenberger M, Lorenzo Bermejo J.
Arsenic and gallbladder cancer risk: Mendelian randomization analysis of European prospective data.
International Journal of Cancer 2020; 146:2648-2650.

Guo F, Chen C, Schöttker B, Holleczek B, Hoffmeister M, Brenner H.
Changes in colorectal cancer screening use after introduction of alternative screening offer in Germany: Prospective cohort study.
International Journal of Cancer 2020; 146:2423-2432.

Anusruti A, Xuan Y, Gào X, Jansen E, Laetsch DC, Brenner H, Schöttker B.
Factors associated with high oxidative stress in type 2 diabetes patients: a meta-analysis of two cohort studies.
BMJ Open Diabetes Research & Care 2020; 8:e000933.

Anusruti A, Jansen EHJM, Gào X, Xuan Y, Brenner H, Schöttker B.
Longitudinal associations of body mass index, waist circumference and waist to hip ratio with biomarkers of oxidative stress in older adults: Results of a large cohort study.
Obesity Facts 2020; 13:66-76.

Boekstegers F, Marcelain K, Ponce CB, Baez Benavides PF, Müller B, de Toro G, Retamales J, Barajas O, Ahumada M, Morales E, Rojas A, Sanhueza V, Loader D, Rivera MT, Gutiérrez L, Bernal G, Ortega A, Montalvo D, Portino S, Bertrán ME, Gabler F, Spencer L, Olloquequi J, Silos RG, Fischer C, Scherer D, Jenab M, Aleksandrova K, Katzke V, Weiderpass E, Moradi T, Fischer K, Bossers W, Brenner H, Hveem K, Eklund N, Völker U, Waldenberger M, Guajardo MF, Gonzalez-Jose R, Bedoya G, Bortolini MC, Canizales S, Gallo C, Linares AR, Rothhammer F, Bermejo JL.
ABCB1/4 Gallbladder cancer risk variants identified in India also show strong effects in Chileans.
Cancer Epidemiology 2020; 65:101643.

Alwers E, Jansen L, Bläker H, Kloor M, Tagscherer K, Roth W, Boakye D, Herpel E, Grüllich C, Chang-Claude J, Brenner H, Hoffmeister M.
Microsatellite instability and survival after adjuvant chemotherapy among stage II and III colon cancer patients: Results from a population-based study.
Molecular Oncology 2020; 14:363-372.

Carr PR, Amitay E, Jansen L, Alwers E, Roth W, Herpel E, Kloor M, Schneider M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.
Association of body mass index and major molecular pathological markers of colorectal cancer among men and women.
American Journal of Clinical Nutrition 2020; 111:562-569.

Beyerle J, Holowatyj AN, Haffa M, Frei E, Gigic B, Schrotz-King P, Böhm J, Habermann N, Stiborova M, Scherer D, Koelsch T, Skender S, Becker N, Herpel E, Schneider M, Ulrich A, Schirmacher P, Chang-Claude J, Brenner H, Hoffmeister M, Haug U, Owen RW, Ulrich CM.
Expression patterns of xenobiotic metabolizing enzymes in tumor and adjacent normal mucosa tissues among patients with colorectal cancer: The ColoCare study.
Cancer Epidemiology, Biomarkers & Prevention 2020; 29:460-469.

Jaeschke L, Steinbrecher A, Boeing H, Gastell S, Ahrens W,..., Brenner H,..., Schipf S, Schmidt B, Zinkhan M, Pischon T.
Factors associated with habitual time spent in different physical activity intensities using multiday accelerometry.
Scientific Reports 2020; 10:774.

Riegger J, Rehm M, Büchele G, Brenner H, Günther KP, Rothenbacher D, Brenner RE.
Serum cartilage oligomeric matrix protein in late-stage osteoarthritis: Association with clinical features, renal function and cardiovascular biomarkers.
Journal of Clinical Medicine 2020; 9:268.

Papadimitriou N, Dimou N, Tsilidis K, Banbury B, Martin R,..., Brenner H,..., Hoffmeister M,..., Wu A, Peters U, Gunter M, Murphy N.
Physical activity and risks of breast and colorectal cancer: a Mendelian randomization analysis.
Nature Communications 2020; 11:597.

Escala-Garcia M, Abraham J, Andrulis IL, Anton-Culver H, Arndt V,..., Brenner H,..., Dörk T, Easton D, Canisius S, Schmidt M.
A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.
Nature Communications 2020; 11:312.

Bhardwaj M, Weigl K, Tikk K, Holland-Letz T, Schrotz-King P, Borchers CH, Brenner H.
Multiplex quantitation of 270 plasma protein markers to identify a signature for early detection of colorectal cancer.
European Journal of Cancer 2020; 127:30-40.

Boehlen FH, Herzog W, Schellberg D, Maatouk I, Schöttker B, Brenner H, Wild B.
Gender-specific predictors of generalized anxiety disorder symptoms in older adults: results of a large population-based study.
Journal of Affective Disorders 2020; 262:174-181.

Schipf S, Schöne G, Schmidt B, Günther K, Stübs G,..., Brenner H,..., Holleczek B,..., Wirkner K, Völzke H, Pischon T, Ahrens W.
Die Basiserhebung der NAKO Gesundheitsstudie: Teilnahme an den Untersuchungsmodulen, Qualitätssicherung und Nutzung von Sekundärdaten.
Bundesgesundheitsblatt 2020; 63:254-266.

Dragano N, Reuter M, Greiser KH, Becher H, Zeeb H,..., Holleczek B, Brenner H,..., Legath N, Ahrens W, Lampert T, Schmidt B.
Soziodemografische und erwerbsbezogene Merkmale in der NAKO Gesundheitsstudie.
Bundesgesungsheitsblatt 2020; 63:267-278.

Leitzmann M, Gastell S, Hillreiner A, Herbolsheimer F, Baumeister SE,..., Brenner H,..., Holleczek B,..., Thierry S, Völzke H, Wirkner K, Steindorf K.
Körperliche Aktivität in der NAKO Gesundheitsstudie: erste Ergebnisse des multimodalen Erhebungskonzepts.
Bundesgesundheitsblatt 2020; 63:301-311.

Karrasch S, Peters A, Meisinger C, Ferland M, Jaeschke L,..., Leitzmann M, Brenner H, Holleczek B, Schulz H.
Lungenfunktion in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse.
Bundesgesundheitsblatt 2020; 63:322-331.

Wolf K, Kraus U, Dzolan M, Bolte G, Lakes T,..., Brenner H,..., Holleczek B,..., Wirkner K, Zschocke J, Peters A, Schneider A.
Nächtliche Vekehrslärmbelästigung in Deutschland: individuelle und regionale Unterschiede in der NAKO Gesundheitsstudie.
Bundesgesundheitsblatt 2020; 63:332-343.

Wiessner C, Keil T, Krist L, Zeeb H, Dragano N,..., Koch-Gallenkamp L,..., Waniek S, Wigmann C, Willich SN, Becher H.
Personen mit Migrationshintergrund in der NAKO Gesundheitsstudie – soziodemografische Merkmale und Vergleiche mit der autochthonen deutschen Bevölkerung.
Bundesgesundheitsblatt 2020; 63:279-289.

Fischer B, Sedlmeier AM, Hartwig S, Schlett CL, Ahrens W,..., Carr PR,..., Niedermaier T,..., Tiller D, Völzke H, Waniek S, Leitzmann MF.
Anthropometrische Messungen in der NAKO Gesundheitsstudie – mehr als nur Größe und Gewicht.
Bundesgesundheitsblatt 2020; 63:290-300.

Kluttig A, Zschocke J, Haerting J, Schmermund A, Gastell S,..., Hoffmeister M,..., Mikolajczyk R, Fischer B, Leitzmann M, Brandes M.
Messung der körperlichen Fitness in der NAKO Gesundheitsstudie – Methoden, Qualitätssicherung und erste deskriptive Ergebnisse.
Bundesgesundheitsblatt 2020; 63:312-321.

Gruner LF, Hoffmeister M, Ludwig L, Brenner H.
Effect of various invitation schemes on use of fecal immunochemical tests (FITs) for colorectal cancer screening: Protocol for a randomized controlled
trial.
JMIR Research Protocols 2020; 9: e16413.

Trares K*, Gào X*, Perna L, Rujescu D, Stocker H, Möllers T, Beyreuther K, Brenner H, Schöttker B.
Associations of urinary 8-iso-prostaglandin F2α levels with all-cause dementia, Alzheimer's disease and vascular dementia incidence: results from a prospective cohort study.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2020; 16:804-813.
*geteilte Erstautorenschaft

Gigic B, Nattenmüller J, Schneider M, Kulu Y, Syrjala K, Böhm J, Schrotz-King P, Brenner H, Colditz GA, Figueiredo JC, Grady WM, Li CI, Shibata D, Siegel EM, Toriola AT, Kauczor HU, Ulrich A, Ulrich C.
The role of CT-quantified body composition on longitudinal health-related quality of life in colorectal cancer patients: the ColoCare study.
Nutrients 2020; 12:1247.

Brunssen A, Jansen L, Eisemann N, Waldmann A, Weberpals J, Kraywinkel K, Eberle A, Holleczek B, Zeissig SR, Brenner H, Katalinic A, for the GEKID Cancer Survival Working Group.
Long-term relative survival from melanoma in Germany 1997-2013.
Melanoma Research (im Druck).

Gunter MJ, Alhomoud S, Arnold M, Brenner H, Burn J, Casey G, Chan AT, Cross AJ, Giovannucci E, Hoover R, Houlston R, Jenkins M, Laurent-Puig P, Peters U, Ransohoff D, Riboli E, Sinha R, Stadler ZK, Brennan P, Chanock SJ.
International cancer seminars: a focus on colorectal cancer.
Annals of Oncology (im Druck).

Yu H, Guan Z, Cuk K, Zhang Y, Brenner H.
Circulating microRNA biomarkers for lung cancer detection in East Asian populations.
Cancers (im Druck).

Yang Y, Wu L, Shu XO, Cai Q, Shu X, Li B, Guo X, Ye F, Michailidou K, Bolla MK, Wang Q, Dennis J, Andrulis IL, Brenner H, Chenevix-Trench G, Campa D, Castelao JE, Gago-Dominguez M, Dörk T, Hollestelle A, Lophatananon A, Muir K, Neuhausen SL, Olsson H, Sandler DP, Simard J, Kraft P, Pharoah PDP, Easton DF, Zheng W, Long J.
Genetically predicted levels of DNA methylation biomarkers and breast cancer risk: data from 228,951 women of European descent.
Journal of the National Cancer Institute (im Druck).

NCD Risk Factor Collaboration (NCD-RisC).*
National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: an analysis of trends in Asian and Western countries.
International Journal of Epidemiology (im Druck).
*Collaborators on behalf of the ESTHER study: Brenner H, Saum KU, Schöttker B

Huang L, Jansen L, Balavarca Y, van der Geest L, Lemmens V, Groot Koerkamp B, van Santvoort HC, Grützmann R, Besselink MG, Schrotz-King P, Brenner H.
Significance of exmined lymp node number in accurate staging and long-term survival in resected stage I-II pancreatic cancer-more is better? A large international population-based cohort study.
Annals of Surgery (im Druck).

Mukama T, Kharazmi E, Xing X, Sundquist K, Sundquist J, Brenner H, Fallah M.
Risk-adapted starting age of screening for relatives of breast cancer patients: Evidence to supplement current screening guidelines.
JAMA Oncology (im Druck).

Holleczek B, Schöttker B, Brenner H.
Helicobacter pylori infection, chronic atrophic gastritis and risk of stomach and esophagus cancer: results from the prospective population-based ESTHER cohort study.
International Journal of Cancer (im Druck).

Raut J, Guan Z, Schrotz-King P, Brenner H.
Whole-blood DNA methylation markers for risk stratification in colorectal cancer screening: A systematic review.
Cancers (im Druck).

Geijsen AJMR, van Roekel EH, van Duijnhoven FJB, Achaintre D, Bachleitner-Hofmann T,…, Brenner H,…, Hoffmeister M,…, Schrotz-King P,…, Ulrich AB, Ulrich CM, Weijenberg MP, Kok DE.
Plasma metabolites associated with colorectal cancer stage: findings from an international consortium.
International Journal of Cancer (im Druck).

Kapoor PM, Lindström S, Behrens S, Wang X, Michailidou K, Bolla MK, Wang Q, Dennis J, Dunning AM, Pharoah PDP, Schmidt MK, Kraft P, Garcia-Closas M, Easton DF, Milne RL, Chang-Claude J, on behalf of the Breast Cancer Association Consortium.*
Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk in the Breast Cancer Association Consortium.
International Journal of Epidemiology (im Druck).
*Co-authors on behalf of ESTHER study: Arndt V, Brenner H, Schöttker B

Laetsch DC, Hoppe LK, Saum KU, Haefeli WE, Brenner H, Schöttker B.
Investigation of a possible association of potentially inappropriate medication for older adults and frailty in a prospective cohort study from Germany.
Age and Ageing (im Druck).

Adam S, Doege D, Koch-Gallenkamp L, Thong MSY, Bertram H, Eberle A, Holleczek B, Pritzkuleit R, Waldeyer-Sauerland M, Waldmann A, Zeissig SR, Jansen L, Rohrmann S, Brenner H, Arndt V.
Age-specific health-related quality of life in disease-free long-term prostate cancer survivors versus male population controls – results from a population-based study.
Supportive Care in Cancer (im Druck).

Khankari NK, Banbury BL, Borges MC, Haycock PC, Albanes D, Arndt V,…, Brenner H,…, Hoffmeister M,…, Murff HJ, Gruber SB, Peters U, Zheng W.
Mendelian randomization of circulating polyunsaturated fatty acids and colorectal cancer risk.
Cancer Epidemiology, Biomarkers and Prevention (im Druck).

Pulte D, Jansen L, Brenner H.
Changes in long term survival after diagnosis with common hematologic malignancies in the early 21st century.
Blood Cancer Journal (im Druck).

Boekstegers F, Marcelain K, Ponce CB, Baez Benavides PF, Müller B, de Toro G, Retamales J, Barajas O, Ahumada M, Morales E, Rojas A, Sanhueza V, Loader D, Rivera MT, Gutiérrez L, Bernal G, Ortega A, Montalvo D, Portino S, Bertrán ME, Gabler F, Spencer L, Olloquequi J, Silos RG, Fischer C, Scherer D, Jenab M, Aleksandrova K, Katzke V, Weiderpass E, Moradi T, Fischer K, Bossers W, Brenner H, Hveem K, Eklund N, Völker U, Waldenberger M, Guajardo MF, Gonzalez-Jose R, Bedoya G, Bortolini MC, Canizales S, Gallo C, Linares AR, Rothhammer F, Bermejo JL.
ABCB1/4 Gallbladder cancer risk variants identified in India also show strong effects in Chileans.
Cancer Epidemiology (im Druck).

Weigl K, Tikk K, Hoffmeister M, Hampe J, Igel S, Kolligs F, Klug SJ, Mansmann U, Müller O, Nagel JM, Pichler M, Schwab M, Schweigler D, Stephan AM, De Toni EN, Brenner H.
Prevalence of a first-degree relative with colorectal cancer and uptake of screening among persons 40 to 54 years old.
Clinical Gastroenterology and Hepatology (im Druck).

Jansen L, Schröder CC, Emrich K, Holleczek B, Pritzkuleit R, Brenner H.
Disclosing progress in cancer survival with less delay.
International Journal of Cancer (im Druck).

Gruner LF, Hoffmeister M, Ludwig L, Brenner H.
Effect of various invitation schemes on use of fecal immunochemical tests (FITs) for colorectal cancer screening: Protocol for a randomized controlled trial.
JMIR Research Protocols (im Druck).

Vishram-Nielsen JKK, Laurent S, Nilsson PM, Linneberg A, Sehested TSG, Greve SV, Pareek M, Palmieri L, Giampaoli S, Donfrancesco C, Kee F, Mancia G, Cesana G, Veronesi G, Kuulasmaa K, Salomaa V, Kontto J, Palosaari T, Sans S, Ferrieres J, Dallongeville J, Söderberg S, Moitry M, Drygas W, Tamosiunas A, Peters A, Brenner H, Njolstad I, Olsen MH.
Does estimated pulse wave velocity add prognostic information? The MORGAM prospective cohort project.
Hypertension (im Druck).

d’Errico M, Alwers E, Zhang Y, Edelmann D, Brenner H, Hoffmeister M.
Identification of prognostic DNA methylation biomarkers in patients with gastrointestinal adenocarcinomas: a systematic review of epigenome-wide studies.
Cancer Treatment Reviews (im Druck).

Global Burden of Disease Cancer Collaboration, Fitzmaurice C, Abate D,…, Brenner H,…, Schöttker B,…, Ziapour A, Zodpey S, Murray CJL.
Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2017: A systematic analysis for the Global Burden of Disease Study.
JAMA Oncology (im Druck).

Ochoa-Rosales C, Portilla-Fernandez E, Nano J, Wilson R, Lehne B, Mishra PP, Gao X, Ghanbari M, Rueda-Ochoa OL, Juvinao-Quintero D, Loh M, Zhang W, Kooner JS, Grabe HJ, Felix SB, Schöttker B, Zhang Y, Gieger C, Müller-Nurasyid M, Heier M, Peters A, Lehtimäki T, Teumer A, Brenner H, Waldenberger M, Ikram MA, van Meurs JBJ, Franco OH, Voortman T, Chambers J, Stricker BH, Muka T.
Cardiovascular and metabolic risk – epigenetic link between statin therapy and type 2 diabetes.
Diabetes Care (im Druck).

Dragano N, Reuter M, Greiser H, Becher H, Zeeb H,…, Brenner H,…, Legath N, Ahrens W, Lampert T, Schmidt B.
Soziodemografische und erwerbsbezogene Merkmale in der NAKO Gesundheitsstudie.
Bundesgesundheitsblatt (im Druck).

Thong MSY, Jansen L, Chang-Claude J, Hoffmeister M, Brenner H, Arndt V.
Association of Iaparoscopic colectomy versus open colectomy on the long-term health-related quality of life of colon cancer survivors.
Surgical Endoscopy (im Druck).

Murphy N, Carreras-Torres R, Song M, Chan AT, Martin RM,…, Brenner H,…, Hoffmeister M,…, Wu AH, Zheng W, Peters U, Gunter MJ.
Circulating levels of insulin-like growth factor 1 and insulin-linke growth factor binding protein 3 associate with risk of colorectal cancer based on serologic and Mendelian randomization analyses.
Gastroenterology (im Druck).

Amitay EL, Carr PR, Jansen L, Alwers E, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.
Postmenopausal hormone replacement therapy and colorectal cancer risk by molecular subtypes and pathways.
International Journal of Cancer (im Druck).

Archambault AN, Su YR, Jeon J, Thomas M, Lin Y,…, Brenner H,…, Hoffmeister M,…, Corley DA, Hsu L, Peters U, Hayes RB.
Cumulative burden of colorectal cancer-associated genetic variants is more strongly associated with early-onset vs late-onset cancer.
Gastroenterology (im Druck).

Peng L, Balavarca Y, Niedermaier T, Weigl K, Hoffmeister M, Brenner H.
Risk-adapted cutoffs in colorectal cancer screening by fecal immunochemical tests.
American Journal of Gastroenterology (im Druck).

Sirri E, Kieschke J, Vohmann C, Katalinic A, Nennecke A, Ressing M, Eberle A, Holleczek B, Jansen L, Brenner H, for the GEKID Cancer Survival Working Group.
Survival of malignant mesothelioma and other rare thoracic cancers in Germany and the United States.
Internal Journal of Cancer (im Druck).

Niedermaier T, Tikk K, Gies A, Bieck S, Brenner H.
Sensitivity of fecal immunochemical test for colorectal cancer detection differs strongly according to stage and location.
Clinical Gastroenterology and Hepatology (im Druck).

Finke I, Behrens G, Schwettmann L, Gerken M, Pritzkuleit R, Holleczek B, Brenner H, Jansen L, for the German Cancer Survival Working Group.
Socioeconomic differences and lung cancer survival in Germany: Investigation based on population-based clinical cancer registration.
Lung Cancer (im Druck).

Kar SP, Brenner H, Giles GG, Huo D, Milne RL, Rennert G, Simard J, Zheng W, Burgess S, Pharoah PDP.
Body mass index and the association between low-density lipoprotein cholesterol as predicted by HMGCR genetic variants and breast cancer risk.
International Journal of Epidemiology (im Druck).

Carr P, Weigl K, Edelmann D, Jansen L, Chang J, Brenner H, Hoffmeister M.
Estimation of absolute risk of colorectal cancer based on healthy lifestyle, genetic risk, and colonoscopy status in a population-based study.
Gastroenterology (im Druck).

Niedermaier T, Amitay E, Gies A, Weigl K, Hoffmeister M, Brenner H.
Impact of inadequate bowel cleansing on colonoscopic findings in routine screening practice.
Clinical and Translational Gastroenterology (im Druck).

Campa D, Gentiluomo M, Obazee O, Ballerini A, Vodickova L,..., Brenner H,..., Schöttker B,..., Kaaks R, Neoptolemos J, Lucchesi M, Canzian F.
Genome-wide association study identifies an early onset pancreatic cancer risk locus.
International Journal of Cancer (im Druck).

Trares K*, Gào X*, Perna L, Rujescu D, Stocker H, Möllers T, Beyreuther K, Brenner H, Schöttker B.
Associations of urinary 8-iso-prostaglandin F2α levels with all-cause dementia, Alzheimer's disease and vascular dementia incidence: results from a prospective cohort study.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association (im Druck).
*geteilte Erstautorenschaft

Neumeyer S, Butterbach K, Banbury BL, Berndt SI, Campbell PT, Chlebowski R, Chan AT, Giovannucci EL, Joshi AD, Ogino S, Song M, McCullough M, Manson JE, Sakoda LC, Schoen RE, Slattery ML, White E, Maalmi H, Win AK, Figueiredo JC, Hopper J, Macrae F, Peters U, Brenner H, Hoffmeister M, Newcomb PA, Chang-Claude J.
Genetic predictors of circulating 25-hydroxyvitamin D and prognosis after colorectal cancer.
Cancer Epidemiology, Biomarkers & Prevention (im Druck).

Amitay E, Carr P, Jansen L, Roth W, Alwers E, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.
Smoking, alcohol consumption and colorectal cancer risk by molecular pathological subtypes and pathways.
British Journal of Cancer (im Druck).

Mukama T, Kharazmi E, Sundquist K, Sundquist J, Brenner H, Fallah M.
Familial risk of breast cancer by dynamic, accumulative, and static definition of family history.
Cancer (im Druck).

Möllers T, Perna L, Stocker H, Ihle P, Schubert I, Schöttker B, Frölich L, Brenner H.
New use of psychotropic medication after hospitalization among people with dementia.
International Journal of Geriatric Psychiatry (im Druck).

Phipps AI*, Alwers E*, Harrison T*, Banbury B, Brenner H, Campbell PT, Chang-Claude J, Buchanan D, Chan AT, Farris AB, Figueiredo J, Gallinger S, Giles G, Hudson T, Newcomb PA, Slattery ML, Song M, Ogino S, Zaidi SH, Hoffmeister M†, Peters U†.
Association between molecular subtypes of colorectal tumors and patient survival, based on pooled analysis of 7 international studies.
Gastroenterology (im Druck).
*geteilte Erstautorenschaft
† geteilte Letztautorenschaft

Campbell PT, Lin Y, Bien SA, Figueiredo JC, Harrison TA, Guinter MJ, Berndt SI, Brenner H, Chan AT, Chang-Claude J, Gallinger SJ, Gapstur SM, Giles GG, Giovannucci E, Gruber SB, Gunter M, Hoffmeister M, Jacobs EJ, Jenkins MA, Le Marchand L, Li L, McLaughlin JR, Murphy N, Milne RL, Newcomb PA, Newton C, Ogino S, Potter JD, Rennert G, Rennert HS, Robinson J, Sakoda LC, Slattery ML, Song Y, White E, Woods MO, Casey G, Hsu L, Peters U.
Association of body mass index with colorectal cancer risk according to genome-wide variants.
Journal of the National Cancer Institute (im Druck).

Peter RS, Meyer ML, Mons U, Schöttker B, Keller F, Schmucker R, Koenig W, Brenner H, Rothenbacher D.
Long-term trajectories of anxiety and depression in patients with stable coronary heart diesase and risk of subsequent cardiovascular events.
Depression and Anxiety (im Druck).

Chen H, Lu M, Liu C, Zou S, Du L, Liao X, Dong D, Wei D, Gao Y, Zhu C, Zhu L, Zheng W, Xiao H, Kong Y, Yin H, Zhou H, Ying R, Wang B, Zhang J, Zhang X, Zhang Q, Zhang X, Zhang Y, Wang H, Guo L, Liu L, Ren J, Shi J, Miao X, Brenner H, Dai M.
Comparative evaluation of participation and diagnostic yield of colonoscopy vs fecal immunochemical test vs risk-adapted screening in colorectal cancer screening: interim analysis of a multicenter randomized controlled trial (TARGET-C).
American Journal of Gastroenterology (im Druck).

Feng H, Gusev A, Pasaniuc B, Wu L, Long J,..., Brenner H,..., Chenevix-Trench G, Zheng W, Kraft P, Jiang X.
Transcriptome-wide association study of breast cancer risk by estrogen-receptor status.
Genetic Epidemiology (im Druck).

Boakye D, Jansen L, Schöttker B, Jansen E, Schneideer M, Halama N, Gào X, Chang-Claude J, Hoffmeister M, Brenner H.
Blood markers of oxidative stress are strongly associated with poorer prognosis in colorectal cancer patients.
International Journal of Cancer (im Druck).

Ali Khan U, Fallah M, Tian Y, Sundquist K, Sundquist J, Brenner H, Kharazmi E.
Personal history of diabetes as important as family history of colorectal cancer for risk of colorectal cancer: A nationalwide cohort study.
American Journal of Gastroenterology (im Druck).

Eyl RE, Koch-Gallenkamp L, Jansen L, Walter V, Carr PR, Hoffmeister M, Chang-Claude J, Brenner H, Arndt V.
Physical activity and long-term quality of life among colorectal cancer survivors – a population-based prospective study.
Cancer Prevention Research (im Druck).

Ji X, Mukherjee S, Landi M, Bossé Y, Joubert P,..., Brenner H, Chanock S, Brennan P, McKay J, Amos C.
Protein-altering germline mutations implicate novel genes related to lung cancer development.
Nature Communications (im Druck).

Tian Y, Kharazmi E, Brenner H, Xu X, Sundquist K, Sundquist J, Fallah M.
Calculating starting age for screening in relatives of patients with colorectal cancer based on data from large nationwide datasets.
Gastroenterology (im Druck).

Gredner T, Niedermaier T, Brenner H, Mons U.
Impact of tobacco control policies on smoking-related cancer incidence in Germany 2020 to 2050 – a simulation study.
Cancer Epidemiology, Biomarkers & Prevention (im Druck).

Jansen L*, Merz M*, Engelhardt M, Weisel K, Scheid C, Straka C, Langer C, Salwender H, Einsele H, Kröger N, Beelen D, Dreger P, Goldschmidt H*, Brenner H*, German National Registry for Stem Cell Transplants (DRST).
Autologous stem cell transplantation in multiple myeloma patients: Utilization patterns and hospital effects.
Leukemia and Lymphoma (im Druck).
*geteilte Erstautorenschaft

Ma J, Rebholz CM, Braun KVE, Reynolds LM, Aslibekyan S,..., Zhang Y, Schöttker B, Brenner H,..., Hu FB, Fornage M, Voortman T, Levy D.
Whole blood DNA methylation signatures of diet are associated with cardiovascular disease risk factors and all-cause mortality.
Circulation: Genomic and Precision Medicine (im Druck).

Eyl RE, Thong MSY, Carr PR, Jansen L, Koch-Gallenkamp L, Hoffmeister M, Chang-Claude J, Brenner H, Arndt V.
Physical activity and long-term fatigue among colorectal cancer survivors – a population-based prospective study.
BMC Cancer (im Druck).

Jansen L, Behrens G, Finke I, Maier W, Gerken M, Pritzkuleit R, Holleczek B, Brenner H.
Area-based socioeconomic inequalities in colorectal cancer survival in Germany: Investigation based on population-based clinical cancer registration.
Frontiers in Oncology (im Druck).

Guo F, Weigl K, Carr PR, Heißer T, Jansen L, Knebel P, Chang-Claude J, Hoffmeister M, Brenner H.
Use of polygenic risk scores to select screening intervals after negative findings from colonoscopy.
Clinical Gastroenterology and Hepatology (im Druck).

Gigic B, Nattenmüller J, Schneider M, Kulu Y, Syrjala K, Böhm J, Schrotz-King P, Brenner H, Colditz GA, Figueiredo JC, Grady WM, Li CI, Shibata D, Siegel EM, Toriola AT, Kauczor HU, Ulrich A, Ulrich C.
The role of CT-quantified body composition on longitudinal health-related quality of life in colorectal cancer patients: the ColoCare study.
Nutrients (im Druck).

Liu J, Prager-van der Smissen WJC, Collée M, Bolla MK, Wang Q,..., Arndt V,..., Brenner H,..., Easton DF, Hooning MJ, Martens JWM, Hollestelle A.
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
Scientific Reports (im Druck).

Stocker H, Perna L, Weigl K, Möllers T, Schöttker B, Thomsen H, Holleczek B, Rujescu D, Brenner H.
Prediction of clinical diagnosis of Alzheimer's disease, vascular, mixed, and all-cause dementia by a polygenic riskscore and APOE status in a community-based prospectively followed over 17 years.
Molecular Psychiatry (im Druck).

Kather JN, Heij LR, Grabsch HI, Loeffler C, Echle A, Muti HS, Krause J, Niehues JM, Sommer KAJ, Bankhead P, Kooreman LFS, Schulte JJ, Cipriani NA, Buelow RD, Boor P, Ortiz-Brüchle N, Hanby AM, Speirs V, Kochanny S, Patnaik A, Srisuwananukorn A, Brenner H, Hoffmeister M, van den Brandt PA, Jäger D, Trautwein C, Pearson AT, Luedde T.
Pan-cancer image-based detection of clinically actionable genetic alterations.
Nature Cancer (im Druck).

Gruner LF, Ludwig L, Hoffmeister M, Meny S, Brenner H.
The effects of different invitation schemes on use of fecal immunochemical tests (FITs): Results from a randomized controlled trial.
Effekte verschiedener Einladungsmodelle auf die Inanspruchnahme immunologischer Tests auf Blut im Stuhl: Ergebnisse einer randomisierten kontrollierten Studie.
Deutsches Ärzteblatt (im Druck).

Kapoor PM, Mavaddat N, Choudhury PP, Wilcox AN, Lindström S,..., Arndt V,..., Brenner H,..., Holleczek B,..., Schöttker B,..., Easton DF, Milne RL, Garcia-Closas M, Chang-Claude J.
Combined associations of a polygenic risk score and classical risk factors with breast cancer risk.
Journal of the National Cancer Institute (im Druck).

Chen LJ, Trares K, Laetsch DC, Nguyen Thi Ngoc M, Brenner H, Schöttker B.
Systematic review and meta-analysis on the associations of polypharmacy and potentially inappropriate medication with adverse outcomes in older cancer patients.
Journal of Gerontology: Medical Sciences (im Druck).

NCD Risk Factor Collaboration (NCD-RisC).*
Repositioning of the global epicenter of non-optimal cholesterol.
Nature (im Druck).
*Collaborators on behalf of the ESTHER study: Brenner H, Saum KU, Schöttker B

Zhang Y, Bewerbunge-Hudler M, Schick M, Burwinkel B, Herpel E, Hoffmeister M, Brenner H.
Blood-derived DNA methylation predictors of mortality discriminate tumor and healthy tissue in multiple organs.
Molecular Oncology (im Druck).

Huynh-Le MP, Chieh Fan C, Karunamuni R, Walsh EI, Turner EL,..., Brenner H, Schöttker B, Holleczek B,..., Mills IG, Andreassen OA, Dale AM, Seibert TM.
A genetic risk score to personalize prostate cancer screening, applied to population data.
Cancer Epidemiology, Biomarkers & Prevention (im Druck).

Schrotz-King P, Hoffmeister M, Sauer P, Schaible A, Brenner H.
Protocol of the DARIO randomized trial: Effects of alternative offers of screening sigmoidoscopy and colonoscopy on utilization and yield of endoscopic screening for colorectal neoplasms.
JMIR Research (im Druck).

 

 

 

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