Research for a life without cancer

Sarcomas in soft tissue usually occur in young people and are particularly difficult to treat. Due to a lack of laboratory models, the causes of their development are still poorly understood. A team of researchers from the Hopp Children's Cancer Centre Heidelberg (KiTZ), the German Cancer Research Centre (DKFZ) and Heidelberg University Hospital (UKHD) has now succeeded in creating mouse models with a functioning immune system that replicate a variety of sarcoma types that remain unstudied. The method opens up new avenues for the targeted development of immunotherapies for children and adolescents with sarcomas. The Hopp Children’s Cancer Center Heidelberg (KiTZ) is a joint institution of the German Cancer Research Center (DKFZ), Heidelberg University Hospital (UKHD) and the University of Heidelberg (Uni HD).