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Searchresult: Translational Neuroblastoma Research
Our Research Neuroblastoma (NB) is the most common pediatric single-entity solid cancer derived from primitive cells of the peripheral sympathetic nervous system. It is characterized by…
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Searchresult: Theoretical Systems Biology
Our Research Present research priorities Given that cancer-associated mutations occur continuously in renewing tissues, such as blood, these tissues are likely to have protective mechanisms in place…
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Searchresult: Brain Tumor Translational Targets
Our Research Glioblastoma stem-like cells (GSCs), which play a crucial role in tumor relapse, exhibit strong resistance to conventional chemo- and radiotherapy due to their robust self-renewal…
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Searchresult: Chromatin Networks
Our Research We integrate single-cell (epi)genomics with advanced fluorescence microscopy methods to understand how chromatin organization and nuclear architecture govern gene regulation and…
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Searchresult: Cancer Genome Research
Our Research Our research comprises the genome-wide analysis of molecular alterations in various cancer entities with an emphasis on lung and breast tumors. To this end, we apply high-throughput…
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Searchresult: Molecular Genome Analysis
Our Research The central objective of our division is to understand the complexity of molecular mechanisms in the regulation of signaling networks and how these impact cancer development,…
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Searchresult: Translational Control and Metabolism
Our Research The demand for building blocks in cancer cells differs greatly from the one of a normal cell. In order to divide, a cell must duplicate its protein content, a process that requires…
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Searchresult: Proteomics of Stem Cells and Cancer
Our Research Proteins are often referred to as the workhorses of the cell, to indicate that they carry out the biochemical processes that give cells their identity and that endow them with…
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Searchresult: Systems Biology of Signal Transduction
Our Research We combine quantitative technologies with mechanism-based mathematical modeling to enable early detection and personalized treatment of cancer to prevent tumor progression and improve…
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Searchresult: RNA-Protein Complexes and Cell Proliferation
PD Dr. Maïwen Caudron-Herger Cells have the wonderful ability to assemble a great variety of dynamic structures performing very complex and specific tasks. Our goal is to improve our understanding of…