We use cookies to optimize our website. These include cookies that are necessary for the operation of the site, as well as those that are only used for anonymous statistic. You can decide for yourself which categories you want to allow. Further information can be found in our data privacy protection .

Essential enable/disable

These cookies are necessary to run the core functionalities of this website and cannot be disabled.

Name	Webedition CMS
Purpose	This cookie is required by the CMS (Content Management System) Webedition for the system to function correctly. Typically, this cookie is deleted when the browser is closed.
Name	econda
Purpose	Session cookie emos_jcsid for the web analysis software econda. This runs in the “anonymized measurement” mode. There is no personal reference. As soon as the user leaves the site, tracking is ended and all data in the browser are automatically deleted.

Statistics enable/disable

These cookies help us understand how visitors interact with our website by collecting and analyzing information anonymously. Depending on the tool, one or more cookies are set by the provider.

Name	econda
Purpose	Statistics

External media enable/disable

Content from external media platforms is blocked by default. If cookies from external media are accepted, access to this content no longer requires manual consent.

Name	YouTube
Purpose	Show YouTube content
Name	Twitter
Purpose	activate Twitter Feeds

Research

Publications of Pediatric Neurooncology

2020

Hasselblatt, M. ; Thomas, C. ; Nemes, K. ; Monoranu, C.-M. ; Riemenschneider, M. J. ; Koch, A. ; Sumerauer, D. ; Hauser, P. ; Paulus, W. ; Johann, P. ; Kool, M. ; Frühwald, M. C.
Tyrosinase immunohistochemistry can be employed for the diagnosis of atypical teratoid/rhabdoid tumours of the tyrosinase subgroup (ATRT-TYR).
Neuropathology & applied neurobiology 46(2), 186-189 (2020) [10.1111/nan.12560]2020 BibTeX | EndNote: XML, Text | RIS

Reisinger, D. ; Gojo, J. ; Kasprian, G. ; Haberler, C. ; Peyrl, A. ; Azizi, A. A. ; Mayr, L. ; Chocholous, M. ; Kool, M. ; Czech, T. ; Slavc, I.
Predisposition of Wingless Subgroup Medulloblastoma for Primary Tumor Hemorrhage.
Neurosurgery 86(4), 478-484 (2020) [10.1093/neuros/nyz148]2020 BibTeX | EndNote: XML, Text | RIS

de Rojas, T. ; Kasper, B. ; Van der Graaf, W. ; Pfister, S. M. ; Bielle, F. ; Ribalta, T. ; Shenjere, P. ; Preusser, M. ; Fröhling, S. ; Golfinopoulos, V. ; Morfouace, M. ; McCabe, M. G.
EORTC SPECTA-AYA: A unique molecular profiling platform for adolescents and young adults with cancer in Europe.
International journal of cancer 147(4), 1180-1184 (2020) [10.1002/ijc.32651]2020 BibTeX | EndNote: XML, Text | RIS

Jabarkheel, R. ; Amayiri, N. ; Yecies, D. ; Huang, Y. ; Toescu, S. ; Nobre, L. ; Mabbott, D. J. ; Sudhakar, S. V. ; Malik, P. ; Laughlin, S. ; Swaidan, M. ; Al Hussaini, M. ; Musharbash, A. ; Chacko, G. ; Mathew, L. G. ; Fisher, P. G. ; Hargrave, D. ; Bartels, U. ; Tabori, U. ; Pfister, S. M. ; Aquilina, K. ; Taylor, M. D. ; Grant, G. A. ; Bouffet, E. ; Mankad, K. ; Yeom, K. W. ; Ramaswamy, V.
Molecular correlates of cerebellar mutism syndrome in medulloblastoma.
Neuro-Oncology 22(2), 290-297 (2020) [10.1093/neuonc/noz158]2020 BibTeX | EndNote: XML, Text | RIS

Wefers, A. (First author) ; Stichel, D. ; Schrimpf, D. ; et al
Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.
Acta neuropathologica 139(1), 193-209 (2020) [10.1007/s00401-019-02078-w]2020 BibTeX | EndNote: XML, Text | RIS

Benesch, M. ; Nemes, K. ; Neumayer, P. ; Hasselblatt, M. ; Timmermann, B. ; Bison, B. ; Ebetsberger-Dachs, G. ; Bourdeaut, F. ; Dufour, C. ; Biassoni, V. ; Morales La Madrid, A. ; Entz-Werle, N. ; Laithier, V. ; Quehenberger, F. ; Weis, S. ; Sumerauer, D. ; Siebert, R. ; Bens, S. ; Schneppenheim, R. ; Kool, M. ; Modena, P. ; Fouyssac, F. ; C Frühwald, M.
Spinal cord atypical teratoid/rhabdoid tumors in children: Clinical, genetic, and outcome characteristics in a representative European cohort.
Pediatric blood & cancer 67(1), e28022 (2020) [10.1002/pbc.28022]2020 BibTeX | EndNote: XML, Text | RIS

Begemann, M. ; Waszak, S. M. ; Robinson, G. W. ; Jäger, N. ; Sharma, T. ; Knopp, C. ; Kraft, F. ; Moser, O. ; Mynarek, M. ; Guerrini-Rousseau, L. ; Brugieres, L. ; Varlet, P. ; Pietsch, T. ; Bowers, D. C. ; Chintagumpala, M. ; Sahm, F. ; Korbel, J. O. ; Rutkowski, S. ; Eggermann, T. ; Gajjar, A. ; Northcott, P. ; Elbracht, M. ; Pfister, S. M. ; Kontny, U. ; Kurth, I.
Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma.
Journal of clinical oncology 38(1), 43-50 (2020) [10.1200/JCO.19.00577]2020 BibTeX | EndNote: XML, Text | RIS

Neumann, J. E. ; Spohn, M. ; Obrecht, D. ; Mynarek, M. ; Thomas, C. ; Hasselblatt, M. ; Dorostkar, M. M. ; Wefers, A. K. ; Frank, S. ; Monoranu, C.-M. ; Koch, A. ; Witt, H. ; Kool, M. ; Pajtler, K. W. ; Rutkowski, S. ; Glatzel, M. ; Schüller, U.
Molecular characterization of histopathological ependymoma variants.
Acta neuropathologica 139(2), 305-318 (2020) [10.1007/s00401-019-02090-0]2020 BibTeX | EndNote: XML, Text | RIS

Chattopadhyay, S. (First author) ; Thomsen, H. ; Weinhold, N. ; Meziane, I. ; Huhn, S. ; da Silva Filho, M. I. ; Vodicka, P. ; Vodickova, L. ; Hoffmann, P. ; Nöthen, M. M. ; Jöckel, K.-H. ; Schmidt, B. ; Landi, S. ; Hajek, R. ; Hallmans, G. ; Pettersson-Kymmer, U. ; Ohlsson, C. ; Milani, P. ; Merlini, G. ; Rowcieno, D. ; Hawkins, P. ; Hegenbart, U. ; Palladini, G. ; Wechalekar, A. ; Schönland, S. O. ; Houlston, R. ; Goldschmidt, H. ; Hemminki, K. ; Försti, A. (Last author)
Eight novel loci implicate shared genetic etiology in multiple myeloma, AL amyloidosis, and monoclonal gammopathy of unknown significance.
Leukemia 34(4), 1187-1191 (2020) [10.1038/s41375-019-0619-1]2020 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Schrimpf, D. ; Stichel, D. ; Reuss, D. E. ; Hasselblatt, M. ; Hagel, C. ; Staszewski, O. ; Hench, J. ; Frank, S. ; Brandner, S. ; Korshunov, A. ; Wick, W. ; Pfister, S. M. ; Reifenberger, G. ; von Deimling, A. ; Sahm, F. (Last author) ; Jones, D. (Last author)
Posterior fossa pilocytic astrocytomas with oligodendroglial features show frequent FGFR1 activation via fusion or mutation.
Acta neuropathologica 139(2), 403-406 (2020) [10.1007/s00401-019-02097-7]2020 BibTeX | EndNote: XML, Text | RIS

Thomas, C. ; Wefers, A. ; Bens, S. ; Nemes, K. ; Agaimy, A. ; Oyen, F. ; Vogelgesang, S. ; Rodriguez, F. J. ; Brett, F. M. ; McLendon, R. ; Bodi, I. ; Burel-Vandenbos, F. ; Keyvani, K. ; Tippelt, S. ; Poulsen, F. R. ; Lipp, E. S. ; Giannini, C. ; Reifenberger, G. ; Kuchelmeister, K. ; Pietsch, T. ; Kordes, U. ; Siebert, R. ; Frühwald, M. C. ; Johann, P. D. ; Sill, M. ; Kool, M. ; von Deimling, A. ; Paulus, W. ; Hasselblatt, M.
Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults.
Acta neuropathologica 139(2), 277-286 (2020) [10.1007/s00401-019-02094-w]2020 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Chiang, J. ; Schrimpf, D. ; Stichel, D. ; Paramasivam, N. ; Sill, M. ; Gayden, T. ; Casalini, B. ; Reuss, D. E. ; Dalton, J. ; Pajtler, K. W. ; Hänggi, D. ; Herold-Mende, C. ; Rushing, E. ; Korshunov, A. ; Mawrin, C. ; Weller, M. ; Schlesner, M. ; Wick, W. ; Jabado, N. ; Jones, D. T. W. ; Pfister, S. M. ; von Deimling, A. ; Ellison, D. W. ; Sahm, F. (Last author)
YAP1-fusions in pediatric NF2-wildtype meningioma.
Acta neuropathologica 139(1), 215-218 (2020) [10.1007/s00401-019-02095-9]2020 BibTeX | EndNote: XML, Text | RIS

Bleeke, M. ; Johann, P. ; Gröbner, S. ; Alten, J. ; Cario, G. ; Schäfer, H. ; Klapper, W. ; Khoury, J. ; Pfister, S. ; Müller, I.
Genome-wide analysis of acute leukemia and clonally related histiocytic sarcoma in a series of three pediatric patients.
Pediatric blood & cancer 67(2), e28074 (2020) [10.1002/pbc.28074]2020 BibTeX | EndNote: XML, Text | RIS

Pfaff, E. (First author) ; Aichmüller, C. ; Sill, M. ; Stichel, D. ; Snuderl, M. ; Karajannis, M. A. ; Schuhmann, M. U. ; Schittenhelm, J. ; Hasselblatt, M. ; Thomas, C. ; Korshunov, A. ; Rhizova, M. ; Wittmann, A. ; Kaufhold, A. ; Iskar, M. ; Ketteler, P. ; Lohmann, D. ; Orr, B. A. ; Ellison, D. W. ; von Hoff, K. ; Mynarek, M. ; Rutkowski, S. ; Sahm, F. ; von Deimling, A. ; Lichter, P. ; Kool, M. ; Zapatka, M. ; Pfister, S. M. ; Jones, D. (Last author)
Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations.
Acta neuropathologica 139(2), 243-257 (2020) [10.1007/s00401-019-02101-0]2020 BibTeX | EndNote: XML, Text | RIS

Korshunov, A. (First author) ; Okonechnikov, K. ; Sahm, F. ; Ryzhova, M. ; Stichel, D. ; Schrimpf, D. ; Ghasemi, D. R. ; Pajtler, K. W. ; Antonelli, M. ; Donofrio, V. ; Mastronuzzi, A. ; Rossi, S. ; Camassei, F. D. ; Buccoliero, A. M. ; Haberler, C. ; Slavc, I. ; Dahiya, S. ; Casalini, B. ; Sievers, P. ; Meyer, J. ; Kumirova, E. ; Zheludkova, O. ; Golanov, A. ; Jones, D. T. W. ; Pfister, S. M. ; Kool, M. ; von Deimling, A. (Last author)
Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker.
Acta neuropathologica 139(3), 583-596 (2020) [10.1007/s00401-019-02102-z]2020 BibTeX | EndNote: XML, Text | RIS

Pickles, J. C. ; Fairchild, A. R. ; Stone, T. J. ; Brownlee, L. ; Merve, A. ; Yasin, S. A. ; Avery, A. ; Ahmed, S. W. ; Ogunbiyi, O. ; Gonzalez Zapata, J. ; Peary, A. F. ; Edwards, M. ; Wilkhu, L. ; Dryden, C. ; Ladon, D. ; Kristiansen, M. ; Rowe, C. ; Kurian, K. M. ; Nicoll, J. A. R. ; Mitchell, C. ; Bloom, T. ; Hilton, D. A. ; Al-Sarraj, S. ; Doey, L. ; Johns, P. N. ; Bridges, L. R. ; Chakrabarty, A. ; Ismail, A. ; Rathi, N. ; Syed, K. ; Lammie, G. A. ; Limback-Stanic, C. ; Smith, C. ; Torgersen, A. ; Rae, F. ; Hill, R. M. ; Clifford, S. C. ; Grabovska, Y. ; Williamson, D. ; Clarke, M. ; Jones, C. ; Capper, D. ; Sill, M. ; von Deimling, A. ; Pfister, S. M. ; Jones, D. T. W. ; Hargrave, D. ; Chalker, J. ; Jacques, T. S.
DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study.
The lancet child & adolescent health 4(2), 121-130 (2020) [10.1016/S2352-4642(19)30342-6]2020 BibTeX | EndNote: XML, Text | RIS

Kommoss, F. K. F. ; Stichel, D. ; Schrimpf, D. ; Kriegsmann, M. ; Tessier-Cloutier, B. ; Talhouk, A. ; McAlpine, J. N. ; Chang, K. T. E. ; Sturm, D. ; Pfister, S. M. ; Romero-Pérez, L. ; Kirchner, T. ; Grünewald, T. G. P. ; Buslei, R. ; Sinn, H.-P. ; Mechtersheimer, G. ; Schirmacher, P. ; Schmidt, D. ; Lehr, H.-A. ; Sahm, F. ; Huntsman, D. G. ; Gilks, C. B. ; Kommoss, F. ; von Deimling, A. (Last author) ; Koelsche, C.
DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics.213
Journal of cancer research and clinical oncology 146(1), 97-104 (2020) [10.1007/s00432-019-03093-w]2020 BibTeX | EndNote: XML, Text | RIS

Chattopadhyay, S. (First author) ; Zheng, G. ; Hemminki, A. ; Försti, A. ; Sundquist, K. ; Sundquist, J. ; Hemminki, K. (Last author)
Influence of family history on risk of second primary cancers and survival in squamous cell skin cancer patients.
British journal of dermatology 183(3), 488-494 (2020) [10.1111/bjd.18809]2020 BibTeX | EndNote: XML, Text | RIS

Hovestadt, V. ; Ayrault, O. ; Swartling, F. J. ; Robinson, G. W. ; Pfister, S. ; Northcott, P. A.
Medulloblastomics revisited: biological and clinical insights from thousands of patients.
Nature reviews / Cancer Cancer [...] 20(1), 42 - 56 (2020) [10.1038/s41568-019-0223-8]2020 BibTeX | EndNote: XML, Text | RIS

Catalano, C. (First author) ; da Silva Filho, M. I. ; Frank, C. ; Lu, S. ; Jiraskova, K. ; Vymetalkova, V. ; Levy, M. ; Liska, V. ; Vycital, O. ; Naccarati, A. ; Vodickova, L. ; Hemminki, K. ; Vodicka, P. ; Weber, A. N. R. ; Försti, A. (Last author)
Epistatic effect of TLR3 and cGAS-STING-IKK?-TBK1-IFN signaling variants on colorectal cancer risk.
Cancer medicine 9(4), 1473-1484 (2020) [10.1002/cam4.2804]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Deng, M. Y. (First author) ; Sill, M. ; Sturm, D. ; Stichel, D. ; Witt, H. ; Ecker, J. ; Wittmann, A. ; Schittenhelm, J. ; Ebinger, M. ; Schuhmann, M. U. ; Figarella-Branger, D. ; Aronica, E. ; Staszewski, O. ; Preusser, M. ; Haberler, C. ; Lauten, M. ; Schüller, U. ; Hartmann, C. ; Snuderl, M. ; Dunham, C. ; Jabado, N. ; Wesseling, P. ; Deckert, M. ; Keyvani, K. ; Gottardo, N. ; Giangaspero, F. ; von Hoff, K. ; Ellison, D. W. ; Pietsch, T. ; Herold Mende, C. ; Milde, T. ; Witt, O. ; Kool, M. ; Korshunov, A. ; Wick, W. ; von Deimling, A. ; Pfister, S. M. ; Jones, D. T. W. ; Sahm, F. (Last author)
Diffuse Glioneuronal tumour with Oligodendroglioma-like features and Nuclear Clusters (DGONC) - a molecularly-defined glioneuronal CNS tumour class displaying recurrent monosomy 14.
Neuropathology & applied neurobiology 46(5), 422-430 (2020) [10.1111/nan.12590]2020 BibTeX | EndNote: XML, Text | RIS

Frühwald, M. C. ; Hasselblatt, M. ; Nemes, K. ; Bens, S. ; Steinbügl, M. ; Johann, P. D. ; Kerl, K. ; Hauser, P. ; Quiroga, E. ; Solano-Paez, P. ; Biassoni, V. ; Gil-da-Costa, M. J. ; Perek-Polnik, M. ; van de Wetering, M. ; Sumerauer, D. ; Pears, J. ; Stabell, N. ; Holm, S. ; Hengartner, H. ; Gerber, N. U. ; Grotzer, M. ; Boos, J. ; Ebinger, M. ; Tippelt, S. ; Paulus, W. ; Furtwängler, R. ; Hernáiz-Driever, P. ; Reinhard, H. ; Rutkowski, S. ; Schlegel, P.-G. ; Schmid, I. ; Kortmann, R.-D. ; Timmermann, B. ; Warmuth-Metz, M. ; Kordes, U. ; Gerss, J. ; Nysom, K. ; Schneppenheim, R. ; Siebert, R. ; Kool, M. (Last author) ; Graf, N.
Age and DNA-methylation subgroup as potential independent risk factors for treatment stratification in children with Atypical Teratoid/Rhabdoid Tumors (ATRT).
Neuro-Oncology 22(7), 1006-1017 (2020) [10.1093/neuonc/noz244]2020 BibTeX | EndNote: XML, Text | RIS

Ho, B. ; Johann, P. D. ; Grabovska, Y. ; Andrianteranagna, M. J. D. D. ; Yao, F. P. ; Frühwald, M. ; Hasselblatt, M. ; Bourdeaut, F. ; Williamson, D. ; Huang, A. ; Kool, M. (Last author)
Molecular subgrouping of Atypical Teratoid / Rhabdoid Tumors (ATRT) - a reinvestigation and current consensus.
Neuro-Oncology 22(5), 613-624 (2020) [10.1093/neuonc/noz235]2020 BibTeX | EndNote: XML, Text | RIS

Dyberg, C. ; Andonova, T. ; Olsen, T. K. ; Brodin, B. ; Kool, M. ; Kogner, P. ; Johnsen, J. I. ; Wickström, M.
Inhibition of Rho-Associated Kinase Suppresses Medulloblastoma Growth.
Cancers 12(1), 73 (2020) [10.3390/cancers12010073]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Sari?, N. ; Selby, M. ; Ramaswamy, V. ; Kool, M. ; Stockinger, B. ; Hogstrand, C. ; Williamson, D. ; Marino, S. ; Taylor, M. D. ; Clifford, S. C. ; Basson, M. A.
The AHR pathway represses TGF?-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma.
Scientific reports 10(1), 148 (2020) [10.1038/s41598-019-56876-z]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Maros, M. E. ; Capper, D. ; Jones, D. T. W. ; Hovestadt, V. ; von Deimling, A. ; Pfister, S. M. ; Benner, A. ; Zucknick, M. ; Sill, M. (Last author)
Machine learning workflows to estimate class probabilities for precision cancer diagnostics on DNA methylation microarray data.
Nature protocols 15(2), 479-512 (2020) [10.1038/s41596-019-0251-6]2020 BibTeX | EndNote: XML, Text | RIS

Fresnais, M. (First author) ; Muck, A. ; Majewsky, M. ; Statz, B. ; Krausert, S. ; Benzel, J. ; Castel, D. ; Le Dret, L. ; Pfister, S. ; Haefeli, W. E. ; Burhenne, J. ; Longuespée, R.
Rapid and Sensitive Drug Quantification in Tissue Sections Using Matrix Assisted Laser Desorption Ionization-Ion Mobility-Mass Spectrometry Profiling.
Journal of the American Society for Mass Spectrometry 31(3), 742-751 (2020) [ 10.1021/jasms.0c00005 ]2020 BibTeX | EndNote: XML, Text | RIS

Group, P. T. C. (Collaboration Author) ; Calabrese, C. ; Davidson, N. R. ; et al
Genomic basis for RNA alterations in cancer.
Nature <London> 578(7793), 129 - 136 (2020) [10.1038/s41586-020-1970-0]2020 BibTeX | EndNote: XML, Text | RIS

Gerstung, M. ; Jolly, C. ; Leshchiner, I. ; Dentro, S. ; Gonzalez, S. ; Rosebrock, D. ; Mitchell, T. J. ; Rubanova, Y. ; Anur, P. ; Yu, K. ; Tarabichi, M. ; Deshwar, A. ; Wintersinger, J. ; Kleinheinz, K. ; Vázquez-García, I. ; Haase, K. ; Jerman, L. ; Sengupta, S. ; Macintyre, G. ; Malikic, S. ; Donmez, N. ; Livitz, D. G. ; Cmero, M. ; Demeulemeester, J. ; Schumacher, S. ; Fan, Y. ; Yao, X. ; Lee, J. ; Schlesner, M. ; Boutros, P. C. ; Bowtell, D. D. ; Zhu, H. ; Getz, G. ; Imielinski, M. ; Beroukhim, R. ; Sahinalp, S. C. ; Ji, Y. ; Peifer, M. ; Markowetz, F. ; Mustonen, V. ; Yuan, K. ; Wang, W. ; Morris, Q. D. ; PCAWGEvolution&HeterogeneityWorkingGroup ; Spellman, P. T. ; Wedge, D. C. ; Van Loo, P. ; PCAWGConsortium
The evolutionary history of 2,658 cancers.
Nature <London> 578(7793), 122 - 128 (2020) [10.1038/s41586-019-1907-7]2020 BibTeX | EndNote: XML, Text | RIS

Sieverling, L. (First author) ; Hong, C. ; Koser, S. D. ; et al
Genomic footprints of activated telomere maintenance mechanisms in cancer.
Nature Communications 11(1), 733 (2020) [10.1038/s41467-019-13824-9]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Packer, R. J. ; Iavarone, A. ; Jones, D. T. W. ; Blakeley, J. O. ; Bouffet, E. ; Fisher, M. J. ; Hwang, E. ; Hawkins, C. ; Kilburn, L. ; MacDonald, T. ; Pfister, S. M. ; Rood, B. ; Rodriguez, F. J. ; Tabori, U. ; Ramaswamy, V. ; Zhu, Y. ; Fangusaro, J. ; Johnston, S. A. ; Gutmann, D. H.
Implications of New Understandings of Gliomas in Children and Adults with NF1: Report of a Consensus Conference.
Neuro-Oncology 22(6), 773-784 (2020) [10.1093/neuonc/noaa036]2020 BibTeX | EndNote: XML, Text | RIS

Tomasova, K. ; Kroupa, M. ; Forsti, A. ; Vodicka, P. ; Vodickova, L.
Telomere maintenance in interplay with DNA repair in pathogenesis and treatment of colorectal cancer.
Mutagenesis 35(3), 261-271 (2020) [10.1093/mutage/geaa005]2020 BibTeX | EndNote: XML, Text | RIS

Hong, D. S. ; DuBois, S. G. ; Kummar, S. ; Farago, A. F. ; Albert, C. M. ; Rohrberg, K. S. ; van Tilburg, C. M. ; Nagasubramanian, R. ; Berlin, J. D. ; Federman, N. ; Mascarenhas, L. ; Geoerger, B. ; Dowlati, A. ; Pappo, A. S. ; Bielack, S. ; Doz, F. ; McDermott, R. ; Patel, J. D. ; Schilder, R. J. ; Tahara, M. ; Pfister, S. M. ; Witt, O. ; Ladanyi, M. ; Rudzinski, E. R. ; Nanda, S. ; Childs, B. H. ; Laetsch, T. W. ; Hyman, D. M. ; Drilon, A.
Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials.
The lancet <London> / Oncology Oncology 21(4), 531-540 (2020) [10.1016/S1470-2045(19)30856-3]2020 BibTeX | EndNote: XML, Text | RIS

Horak, P. (First author) ; Uhrig, S. ; Witzel, M. ; Gil-Farina, I. ; Hutter, B. ; Rath, T. ; Gieldon, L. ; Balasubramanian, G. P. ; Pastor, X. ; Heilig, C. E. ; Richter, D. ; Schröck, E. ; Ball, C. R. ; Brors, B. ; Braun, C. J. ; Albert, M. H. ; Scholl, C. ; von Kalle, C. ; Schmidt, M. ; Fröhling, S. ; Klein, C. ; Glimm, H.
Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia.
Leukemia 34(10), 2785-2789 (2020) [10.1038/s41375-020-0779-z]2020 BibTeX | EndNote: XML, Text | RIS

Calandrini, C. ; Schutgens, F. ; Oka, R. ; Margaritis, T. ; Candelli, T. ; Mathijsen, L. ; Ammerlaan, C. ; van Ineveld, R. L. ; Derakhshan, S. ; de Haan, S. ; Dolman, E. ; Lijnzaad, P. ; Custers, L. ; Begthel, H. ; Kerstens, H. H. D. ; Visser, L. L. ; Rookmaaker, M. ; Verhaar, M. ; Tytgat, G. A. M. ; Kemmeren, P. ; de Krijger, R. R. ; Al-Saadi, R. ; Pritchard-Jones, K. ; Kool, M. ; Rios, A. C. ; van den Heuvel-Eibrink, M. M. ; Molenaar, J. J. ; van Boxtel, R. ; Holstege, F. C. P. ; Clevers, H. ; Drost, J.
An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity.
Nature Communications 11(1), 1310 (2020) [10.1038/s41467-020-15155-6]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Aichmüller, C. (First author) ; Iskar, M. ; Jones, D. T. W. ; Korshunov, A. ; Radlwimmer, B. ; Kool, M. ; Ernst, A. ; Pfister, S. M. ; Lichter, P. ; Zapatka, M. (Last author)
Pilocytic Astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response.
Neuro-Oncology 22(9), 1327-1338 (2020) [10.1093/neuonc/noaa035]2020 BibTeX | EndNote: XML, Text | RIS

Castel, D. ; Kergrohen, T. ; Tauziède-Espariat, A. ; Mackay, A. ; Ghermaoui, S. ; Lechapt, E. ; Pfister, S. M. ; Kramm, C. M. ; Boddaert, N. ; Blauwblomme, T. ; Puget, S. ; Beccaria, K. ; Jones, C. ; Jones, D. T. W. ; Varlet, P. ; Grill, J. ; Debily, M.-A.
Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation.
Acta neuropathologica 139(5), 1109-1113 (2020) [10.1007/s00401-020-02142-w]2020 BibTeX | EndNote: XML, Text | RIS

Schubert, N. A. ; Lowery, C. D. ; Bergthold, G. ; Koster, J. ; Eleveld, T. F. ; Rodríguez, A. ; Jones, D. T. W. ; German Cancer Research Center , H. (DKFZ) ; Vassal, G. ; Stancato, L. F. ; Pfister, S. M. ; German Cancer Research Center , H. (DKFZ) ; Heidelberg University Hospital, H. ; Caron, H. N. ; Molenaar, J. J.
Systematic target actionability reviews of preclinical proof-of-concept papers to match targeted drugs to paediatric cancers.
European journal of cancer 130, 168 - 181 (2020) [10.1016/j.ejca.2020.01.027]2020 Files BibTeX | EndNote: XML, Text | RIS

Clarke, M. ; Mackay, A. ; Ismer, B. ; et al
Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes.
Cancer discovery 10(7), 942-963 (2020) [10.1158/2159-8290.CD-19-1030]2020 BibTeX | EndNote: XML, Text | RIS

Waszak, S. ; Robinson, G. ; Gudenas, B. L. ; et al
Germline Elongator mutations in Sonic Hedgehog medulloblastoma
Nature <London> 580(7803), 396 - 401 (2020) [10.1038/s41586-020-2164-5]2020 BibTeX | EndNote: XML, Text | RIS

Johann, P. D. (Last author)
Invited Review: Dysregulation of chromatin remodellers in paediatric brain tumours - SMARCB1 and beyond.
Neuropathology & applied neurobiology 46(1), 57 - 72 (2020) [10.1111/nan.12616]2020 BibTeX | EndNote: XML, Text | RIS

Srivastava, A. (First author) ; Giangiobbe, S. (First author) ; Kumar, A. ; Paramasivam, N. ; Dymerska, D. ; Behnisch, W. ; Witzens-Harig, M. ; Lubinski, J. ; Hemminki, K. ; Försti, A. ; Bandapalli, O. R. (Last author)
Identification of Familial Hodgkin Lymphoma Predisposing Genes Using Whole Genome Sequencing.
Frontiers in Bioengineering and Biotechnology 8, 179 (2020) [10.3389/fbioe.2020.00179]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Mynarek, M. ; von Hoff, K. ; Pietsch, T. ; Ottensmeier, H. ; Warmuth-Metz, M. ; Bison, B. ; Pfister, S. ; Korshunov, A. ; Sharma, T. ; Jaeger, N. ; Ryzhova, M. ; Zheludkova, O. ; Golanov, A. ; Rushing, E. J. ; Hasselblatt, M. ; Koch, A. ; Schüller, U. ; von Deimling, A. ; Sahm, F. ; Sill, M. ; Riemenschneider, M. J. ; Dohmen, H. ; Monoranu, C. M. ; Sommer, C. ; Staszewski, O. ; Mawrin, C. ; Schittenhelm, J. ; Brück, W. ; Filipski, K. ; Hartmann, C. ; Meinhardt, M. ; Pietschmann, K. ; Haberler, C. ; Slavc, I. ; Gerber, N. U. ; Grotzer, M. ; Benesch, M. ; Schlegel, P. G. ; Deinlein, F. ; von Bueren, A. O. ; Friedrich, C. ; Juhnke, B.-O. ; Obrecht, D. ; Fleischhack, G. ; Kwiecien, R. ; Faldum, A. ; Kortmann, R. D. ; Kool, M. ; Rutkowski, S.
Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort.
Journal of clinical oncology 38(18), 2028-2040 (2020) [10.1200/JCO.19.03057]2020 BibTeX | EndNote: XML, Text | RIS

Theruvath, J. ; Sotillo, E. ; Mount, C. W. ; Graef, C. M. ; Delaidelli, A. ; Heitzeneder, S. ; Labanieh, L. ; Dhingra, S. ; Leruste, A. ; Majzner, R. G. ; Xu, P. ; Mueller, S. ; Yecies, D. W. ; Finetti, M. A. ; Williamson, D. ; Johann, P. D. ; Kool, M. ; Pfister, S. ; Hasselblatt, M. ; Frühwald, M. C. ; Delattre, O. ; Surdez, D. ; Bourdeaut, F. ; Puget, S. ; Zaidi, S. ; Mitra, S. S. ; Cheshier, S. ; Sorensen, P. H. ; Monje, M. ; Mackall, C. L.
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.
Nature medicine 26(5), 712-719 (2020) [10.1038/s41591-020-0821-8]2020 BibTeX | EndNote: XML, Text | RIS

Bremer, J. ; Kottke, R. ; Johann, P. D. ; von Hoff, K. ; Brazzola, P. ; Grotzer, M. A. ; Kool, M. ; Rushing, E. ; Gerber, N. U.
A single supratentorial high-grade neuroepithelial tumor with two distinct BCOR mutations, exceptionally long complete remission and survival.
Pediatric blood & cancer 67(7), e28384 (2020) [10.1002/pbc.28384]2020 BibTeX | EndNote: XML, Text | RIS

van Tilburg, C. M. (First author) ; Witt, R. ; Heiss, M. ; Pajtler, K. W. ; Plass, C. ; Poschke, I. ; Platten, M. ; Harting, I. ; Sedlaczek, O. ; Freitag, A. ; Meyrath, D. ; Taylor, L. ; Balasubramanian, G. P. ; Jäger, N. ; Pfaff, E. ; Jones, B. C. ; Milde, T. ; Pfister, S. M. ; Jones, D. T. W. ; Kopp-Schneider, A. ; Witt, O. (Last author)
INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies
BMC cancer 20(1), 523 (2020) [10.1186/s12885-020-07008-8]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

ICGC/TCGAPan-CancerAnalysisofWholeGenomesConsortium
Pan-cancer analysis of whole genomes.
Nature <London> 578(7793), 82 - 93 (2020) [10.1038/s41586-020-1969-6]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Ellison, D. W. ; Aldape, K. D. ; Capper, D. ; Fouladi, M. ; Gilbert, M. R. ; Gilbertson, R. J. ; Hawkins, C. ; Merchant, T. ; Pajtler, K. ; Venneti, S. ; Louis, D. N.
cIMPACT-NOW update 7: advancing the molecular classification of ependymal tumors.
Brain pathology 30(5), 863-866 (2020) [10.1111/bpa.12866]2020 BibTeX | EndNote: XML, Text | RIS

Srivastava, A. (First author) ; Miao, B. (First author) ; Skopelitou, D. ; Kumar, V. ; Kumar, A. ; Paramasivam, N. ; Bonora, E. ; Hemminki, K. ; Försti, A. (Last author) ; Bandapalli, O. R. (Last author)
A Germline Mutation in the POT1 Gene Is a Candidate for Familial Non-Medullary Thyroid Cancer.
Cancers 12(6), 1441 (2020) [10.3390/cancers12061441]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Weber, J. ; Braun, C. J. ; Saur, D. ; Rad, R.
In vivo functional screening for systems-level integrative cancer genomics.
Nature reviews / Cancer Cancer 20(10), 573-593 (2020) [10.1038/s41568-020-0275-9]2020 BibTeX | EndNote: XML, Text | RIS

Usta, D. (First author) ; Sigaud, R. ; Buhl, J. L. ; Selt, F. ; Marquardt, V. ; Pauck, D. ; Jansen, J. ; Pusch, S. ; Ecker, J. ; Hielscher, T. ; Vollmer, J. ; Sommerkamp, A. C. ; Rubner, T. ; Hargrave, D. ; van Tilburg, C. M. ; Pfister, S. M. ; Jones, D. T. W. ; Remke, M. ; Brummer, T. ; Witt, O. ; Milde, T. (Last author)
A cell-based MAPK reporter assay reveals synergistic MAPK pathway activity suppression by MAPK inhibitor combination in BRAF-driven pediatric low-grade glioma cells.
Molecular cancer therapeutics 19(8), 1736-1750 (2020) [10.1158/1535-7163.MCT-19-1021]2020 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Hielscher, T. ; Schrimpf, D. ; Stichel, D. ; Reuss, D. E. ; Berghoff, A. S. ; Neidert, M. C. ; Wirsching, H.-G. ; Mawrin, C. ; Ketter, R. ; Paulus, W. ; Reifenberger, G. ; Lamszus, K. ; Westphal, M. ; Etminan, N. ; Ratliff, M. ; Herold-Mende, C. ; Pfister, S. M. ; Jones, D. T. W. ; Weller, M. ; Harter, P. N. ; Wick, W. ; Preusser, M. ; von Deimling, A. ; Sahm, F. (Last author)
CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas.
Acta neuropathologica 140(3), 409-413 (2020) [10.1007/s00401-020-02188-w]2020 BibTeX | EndNote: XML, Text | RIS

Sommerkamp, A. (First author) ; Uhrig, S. ; Stichel, D. ; St-Onge, P. ; Sun, P. ; Jäger, N. ; von Deimling, A. ; Sahm, F. ; Pfister, S. M. ; Korshunov, A. ; Sinnett, D. ; Jabado, N. ; Wefers, A. K. ; Jones, D. (Last author)
An optimized workflow to improve reliability of detection of KIAA1549:BRAF fusions from RNA sequencing data.
Acta neuropathologica 140(2), 237-239 (2020) [10.1007/s00401-020-02167-1]2020 BibTeX | EndNote: XML, Text | RIS

Went, M. ; Cornish, A. J. ; Law, P. J. ; Kinnersley, B. ; van Duin, M. ; Weinhold, N. ; Försti, A. ; Hansson, M. ; Sonneveld, P. ; Goldschmidt, H. ; Morgan, G. J. ; Hemminki, K. ; Nilsson, B. ; Kaiser, M. ; Houlston, R. S.
Search for multiple myeloma risk factors using Mendelian randomization.
Blood advances 4(10), 2172 - 2179 (2020) [10.1182/bloodadvances.2020001502]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Sill, M. (First author) ; Plass, C. ; Pfister, S. M. ; Lipka, D. (Last author)
Molecular tumor classification using DNA methylome analysis.
Human molecular genetics 29(R2), R205-R213 (2020) [10.1093/hmg/ddaa147]2020 BibTeX | EndNote: XML, Text | RIS

Blunk, I. ; Thomsen, H. ; Reinsch, N. ; Mayer, M. ; Försti, A. ; Sundquist, J. ; Sundquist, K. ; Hemminki, K. (Last author)
Genomic imprinting analyses identify maternal effects as a cause of phenotypic variability in type 1 diabetes and rheumatoid arthritis.
Scientific reports 10(1), 11562 (2020) [10.1038/s41598-020-68212-x]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Gojo, J. ; Englinger, B. ; Jiang, L. ; Hübner, J. M. ; Shaw, M. L. ; Hack, O. A. ; Madlener, S. ; Kirchhofer, D. ; Liu, I. ; Pyrdol, J. ; Hovestadt, V. ; Mazzola, E. ; Mathewson, N. D. ; Trissal, M. ; Lötsch, D. ; Dorfer, C. ; Haberler, C. ; Halfmann, A. ; Mayr, L. ; Peyrl, A. ; Geyeregger, R. ; Schwalm, B. ; Mauermann, M. ; Pajtler, K. W. ; Milde, T. ; Shore, M. E. ; Geduldig, J. E. ; Pelton, K. ; Czech, T. ; Ashenberg, O. ; Wucherpfennig, K. W. ; Rozenblatt-Rosen, O. ; Alexandrescu, S. ; Ligon, K. L. ; Pfister, S. M. ; Regev, A. ; Slavc, I. ; Berger, W. ; Suvà, M. L. ; Kool, M. (Last author) ; Filbin, M. G.
Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma.
Cancer cell 38(1), 44 - 59.e9 (2020) [10.1016/j.ccell.2020.06.004]2020 Files BibTeX | EndNote: XML, Text | RIS

Sánchez-Maldonado, J. M. ; Campa, D. ; Springer, J. ; Badiola, J. ; Niazi, Y. ; Moñiz-Díez, A. ; Hernández-Mohedo, F. ; González-Sierra, P. ; Ter Horst, R. ; Macauda, A. ; Brezina, S. ; Cunha, C. ; Lackner, M. ; López-Nevot, M. A. ; Fianchi, L. ; Pagano, L. ; López-Fernández, E. ; Potenza, L. ; Luppi, M. ; Moratalla, L. ; Rodríguez-Sevilla, J. J. ; Fonseca, J. E. ; Tormo, M. ; Solano, C. ; Clavero, E. ; Romero, A. ; Li, Y. ; Lass-Flörl, C. ; Einsele, H. ; Vazquez, L. ; Loeffler, J. ; Hemminki, K. ; Carvalho, A. ; Netea, M. G. ; Gsur, A. ; Dumontet, C. ; Canzian, F. ; Försti, A. ; Jurado, M. ; Sainz, J.
Host immune genetic variations influence the risk of developing acute myeloid leukaemia: results from the NuCLEAR consortium.
Blood cancer journal 10(7), 75 (2020) [10.1038/s41408-020-00341-y]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Szulzewsky, F. ; Arora, S. ; Hoellerbauer, P. ; King, C. ; Nathan, E. ; Chan, M. ; Cimino, P. J. ; Ozawa, T. ; Kawauchi, D. ; Pajtler, K. W. ; Gilbertson, R. J. ; Paddison, P. J. ; Vasioukhin, V. ; Gujral, T. S. ; Holland, E. C.
Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.
Genes & development 34(15-16), 1051-1064 (2020) [10.1101/gad.338681.120]2020 BibTeX | EndNote: XML, Text | RIS

Fresnais, M. ; Roth, A. ; Foerster, K. I. ; Jäger, D. ; Pfister, S. M. ; Haefeli, W. E. ; Burhenne, J. ; Longuespée, R.
Rapid and Sensitive Quantification of Osimertinib in Human Plasma Using a Fully Validated MALDI-IM-MS/MS Assay.
Cancers 12(7), E1897 (2020) [10.3390/cancers12071897]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Lambo, S. (First author) ; von Hoff, K. ; Korshunov, A. ; Pfister, S. M. ; Kool, M. (Last author)
ETMR: a tumor entity in its infancy
Acta neuropathologica 140(3), 249-266 (2020) [10.1007/s00401-020-02182-2]2020 BibTeX | EndNote: XML, Text | RIS

Thomsen, H. (First author) ; Li, X. ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, K. (Last author)
Familial risks between Graves disease and Hashimoto thyroiditis and other autoimmune diseases in the population of Sweden.
Journal of translational autoimmunity 3, 100058 (2020) [10.1016/j.jtauto.2020.100058]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Susanto, E. ; Marin Navarro, A. ; Zhou, L. ; Sundström, A. ; van Bree, N. ; Stantic, M. ; Moslem, M. ; Tailor, J. ; Rietdijk, J. ; Zubillaga, V. ; Hübner, J.-M. ; Weishaupt, H. ; Wolfsberger, J. ; Alafuzoff, I. ; Nordgren, A. ; Magnaldo, T. ; Siesjö, P. ; Johnsen, J. I. ; Kool, M. ; Tammimies, K. ; Darabi, A. ; Swartling, F. J. ; Falk, A. ; Wilhelm, M.
Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America 117(33), 20127-20138 (2020) [10.1073/pnas.1920521117]2020 BibTeX | EndNote: XML, Text | RIS

Hemminki, K. (First author) ; Srivastava, A. ; Rachakonda, S. ; Bandapalli, O. ; Nagore, E. ; Hemminki, A. ; Kumar, R. (Last author)
Informing patients about their mutation tests: CDKN2A c.256G>A in melanoma as an example.
Hereditary cancer in clinical practice 18(1), 15 (2020) [10.1186/s13053-020-00146-x]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Becker, M. ; Noll-Puchta, H. ; Amend, D. ; Nolte, F. ; Fuchs, C. ; Jeremias, I. ; Braun, C. J. (Last author)
CLUE: a bioinformatic and wet-lab pipeline for multiplexed cloning of custom sgRNA libraries.
Nucleic acids research 48(13), e78 (2020) [10.1093/nar/gkaa459]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Banan, R. ; Stichel, D. ; Bleck, A. ; Hong, B. ; Lehmann, U. ; Suwala, A. ; Reinhardt, A. ; Schrimpf, D. ; Buslei, R. ; Stadelmann, C. ; Ehlert, K. ; Prinz, M. ; Acker, T. ; Schittenhelm, J. ; Kaul, D. ; Schweizer, L. ; Capper, D. ; Harter, P. ; Etminan, N. ; Jones, D. T. W. ; Pfister, S. M. ; Herold-Mende, C. ; Wick, W. ; Sahm, F. ; von Deimling, A. ; Hartmann, C. ; Reuß, D. (Last author)
Infratentorial IDH-mutant astrocytoma is a distinct subtype.
Acta neuropathologica 140(4), 569-581 (2020) [10.1007/s00401-020-02194-y]2020 BibTeX | EndNote: XML, Text | RIS

Kutscher, L. (First author) ; Okonechnikov, K. (First author) ; Batora, N. (First author) ; Clark, J. ; Silva, P. B. G. ; Vouri, M. ; van Rijn, S. ; Sieber, L. ; Statz, B. ; Gearhart, M. D. ; Shiraishi, R. ; Mack, N. ; Orr, B. A. ; Korshunov, A. ; Gudenas, B. L. ; Smith, K. S. ; Mercier, A. L. ; Ayrault, O. ; Hoshino, M. ; Kool, M. ; von Hoff, K. ; Graf, N. ; Fleishhack, G. ; Bardwell, V. J. ; Pfister, S. M. ; Northcott, P. A. ; Kawauchi, D. (Last author)
Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation.
Genes & development 34(17-18), 1161-1176 (2020) [10.1101/gad.337584.120]2020 BibTeX | EndNote: XML, Text | RIS

Zheng, G. (First author) ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, A. ; Hemminki, K. (Last author)
Incidence Differences Between First Primary Cancers and Second Primary Cancers Following Skin Squamous Cell Carcinoma as Etiological Clues.
Clinical epidemiology 12, 857 - 864 (2020) [10.2147/CLEP.S256662]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Fittall, M. W. ; Lyskjaer, I. ; Ellery, P. ; Lombard, P. ; Ijaz, J. ; Strobl, A.-C. ; Oukrif, D. ; Tarabichi, M. ; Sill, M. ; Koelsche, C. ; Mechtersheimer, G. ; Demeulemeester, J. ; Tirabosco, R. ; Amary, F. ; Campbell, P. J. ; Pfister, S. ; Jones, D. T. W. ; Pillay, N. ; Van Loo, P. ; Behjati, S. ; Flanagan, A. M.
Drivers underpinning the malignant transformation of giant cell tumour of bone.
The journal of pathology 252(4), 433-440 (2020) [10.1002/path.5537]2020 BibTeX | EndNote: XML, Text | RIS

Parisian, A. D. ; Koga, T. ; Miki, S. ; Johann, P. D. ; Kool, M. ; Crawford, J. R. ; Furnari, F. B.
SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability.
Genes & development 34(19-20), 1316-1329 (2020) [10.1101/gad.339978.120]2020 BibTeX | EndNote: XML, Text | RIS

Zheng, G. (First author) ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, A. ; Hemminki, K. (Last author)
Rate differences between first and second primary cancers may outline immune dysfunction as a key risk factor.
Cancer medicine 9(21), 8258-8265 (2020) [10.1002/cam4.3454]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Li, Y. ; Roberts, N. D. ; Wala, J. A. ; Shapira, O. ; Schumacher, S. E. ; Kumar, K. ; Khurana, E. ; Waszak, S. ; Korbel, J. O. ; Haber, J. E. ; Imielinski, M. ; PCAWGStructuralVariationWorkingGroup ; Weischenfeldt, J. ; Beroukhim, R. ; Campbell, P. J. ; PCAWGConsortium
Patterns of somatic structural variation in human cancer genomes.
Nature <London> 578(7793), 112 - 121 (2020) [10.1038/s41586-019-1913-9]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Zheng, G. (First author) ; Catalano, C. (First author) ; Bandapalli, O. R. ; Paramasivam, N. ; Chattopadhyay, S. ; Schlesner, M. ; Sijmons, R. ; Hemminki, A. ; Dymerska, D. ; Lubinski, J. ; Hemminki, K. (Last author) ; Försti, A. (Last author)
Cancer Predisposition Genes in Cancer-Free Families.
Cancers 12(10), 2770 (2020) [10.3390/cancers12102770]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Niazi, Y. (First author) ; Thomsen, H. ; Smolkova, B. ; Vodickova, L. ; Vodenkova, S. ; Kroupa, M. ; Vymetalkova, V. ; Kazimirova, A. ; Barancokova, M. ; Volkovova, K. ; Staruchova, M. ; Hoffmann, P. ; Nöthen, M. M. ; Dusinska, M. ; Musak, L. ; Vodicka, P. ; Hemminki, K. ; Försti, A. (Last author)
Impact of genetic polymorphisms in kinetochore and spindle assembly genes on chromosomal aberration frequency in healthy humans
Mutation research / Genetic toxicology and environmental mutagenesis 858-860, 503253 (2020) [10.1016/j.mrgentox.2020.503253]2020 BibTeX | EndNote: XML, Text | RIS

Selt, F. (First author) ; van Tilburg, C. M. ; Bison, B. ; Sievers, P. ; Harting, I. ; Ecker, J. ; Pajtler, K. W. ; Sahm, F. ; Bahr, A. ; Simon, M. ; Jones, D. T. W. ; Well, L. ; Mautner, V.-F. ; Capper, D. ; Hernáiz Driever, P. ; Gnekow, A. ; Pfister, S. M. ; Witt, O. ; Milde, T. (Last author)
Response to trametinib treatment in progressive pediatric low-grade glioma patients.
Journal of neuro-oncology 149(3), 499-510 (2020) [10.1007/s11060-020-03640-3]2020 BibTeX | EndNote: XML, Text | RIS

Zhang, Z. ; Bartsch, J. W. ; Benzel, J. ; Lei, T. ; Nimsky, C. ; Voellger, B.
Selective estrogen receptor modulators decrease invasiveness in pituitary adenoma cell lines AtT-20 and TtT/GF by affecting expression of MMP-14 and ADAM12.
FEBS Open Bio 10(11), 2489-2498 (2020) [10.1002/2211-5463.12999]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Rusert, J. M. ; Juarez, E. F. ; Brabetz, S. ; Jensen, J. ; Garancher, A. ; Chau, L. Q. ; Tacheva-Grigorova, S. K. ; Wahab, S. ; Udaka, Y. T. ; Finlay, D. ; Seker-Cin, H. ; Reardon, B. ; Gröbner, S. ; Serrano, J. ; Ecker, J. ; Qi, L. ; Kogiso, M. ; Du, Y. ; Baxter, P. A. ; Henderson, J. J. ; Berens, M. E. ; Vuori, K. ; Milde, T. ; Cho, Y.-J. ; Li, X.-N. ; Olson, J. M. ; Reyes, I. ; Snuderl, M. ; Wong, T. C. ; Dimmock, D. P. ; Nahas, S. A. ; Malicki, D. ; Crawford, J. R. ; Levy, M. L. ; Van Allen, E. M. ; Pfister, S. ; Tamayo, P. ; Kool, M. ; Mesirov, J. P. ; Wechsler-Reya, R. J.
Functional precision medicine identifies new therapeutic candidates for medulloblastoma.
Cancer research 80(23), 5393-5407 (2020) [10.1158/0008-5472.CAN-20-1655]2020 BibTeX | EndNote: XML, Text | RIS

Thomsen, H. (First author) ; Li, X. ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, K. (Last author)
Familial associations between autoimmune hepatitis and primary biliary cholangitis and other autoimmune diseases.
PLOS ONE 15(10), e0240794 - (2020) [10.1371/journal.pone.0240794]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Thomsen, H. ; Li, X. ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, K. (Last author)
Familial associations for Addison disease and between Addison disease and other autoimmune diseases.
Endocrine Connections 9(11), 1114-1120 (2020) [10.1530/EC-20-0328]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Malik, G. ; Agarwal, T. ; Raj, U. ; Sundararajan, V. S. ; Bandapalli, O. R. ; Suravajhala, P.
Hypothetical Proteins as Predecessors of Long Non-coding RNAs
Current genomics 21(7), 531 - 535 (2020) [10.2174/1389202921999200611155418]2020 BibTeX | EndNote: XML, Text | RIS

Mata, D. A. ; Benhamida, J. K. ; Lin, A. L. ; Vanderbilt, C. M. ; Yang, S.-R. ; Villafania, L. B. ; Ferguson, D. C. ; Jonsson, P. ; Miller, A. M. ; Tabar, V. ; Brennan, C. W. ; Moss, N. S. ; Sill, M. ; Benayed, R. ; Mellinghoff, I. K. ; Rosenblum, M. K. ; Arcila, M. E. ; Ladanyi, M. ; Bale, T. A.
Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions.
Acta Neuropathologica Communications 8(1), 186 (2020) [10.1186/s40478-020-01058-6]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Dietzsch, S. ; Placzek, F. ; Pietschmann, K. ; von Bueren, A. O. ; Matuschek, C. ; Glück, A. ; Guckenberger, M. ; Budach, V. ; Welzel, J. ; Pöttgen, C. ; Schmidberger, H. ; Heinzelmann, F. ; Paulsen, F. ; Escudero, M. P. ; Schwarz, R. ; Hornung, D. ; Martini, C. ; Grosu, A. L. ; Stueben, G. ; Jablonska, K. ; Dunst, J. ; Stranzl-Lawatsch, H. ; Dieckmann, K. ; Timmermann, B. ; Pietsch, T. ; Warmuth-Metz, M. ; Bison, B. ; Kwiecien, R. ; Benesch, M. ; Gerber, N. U. ; Grotzer, M. A. ; Pfister, S. M. ; Clifford, S. C. ; von Hoff, K. ; Klagges, S. ; Rutkowski, S. ; Kortmann, R.-D. ; Mynarek, M.
Evaluation of Prognostic Factors and Role of Participation in a Randomized Trial or a Prospective Registry in Pediatric and Adolescent Nonmetastatic Medulloblastoma ? A Report From the HIT 2000 Trial
Advances in radiation oncology 5(6), 1158-1169 (2020) [10.1016/j.adro.2020.09.018]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Bailey, M. H. ; Meyerson, W. U. ; Dursi, L. J. ; et al
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Nature Communications 11(1), 4748 (2020) [10.1038/s41467-020-18151-y]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Thomsen, H. (First author) ; Li, X. ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, K. (Last author)
Familial associations for rheumatoid autoimmune diseases.
Rheumatology advances in practice 4(2), rkaa048 (2020) [10.1093/rap/rkaa048]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Chen, C. C. L. ; Deshmukh, S. ; Jessa, S. ; et al
Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
Cell 183(6), 1617-1633.e22 (2020) [10.1016/j.cell.2020.11.012]2020 BibTeX | EndNote: XML, Text | RIS

Thomsen, H. (First author) ; Li, X. ; Sundquist, K. ; Sundquist, J. ; Försti, A. ; Hemminki, K. (Last author)
Familial risks between giant cell arteritis and Takayasu arteritis and other autoimmune diseases in the population of Sweden.
Scientific reports 10(1), 20887 (2020) [10.1038/s41598-020-77857-7]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Colmenero-Repiso, A. ; Gómez-Muñoz, M. A. ; Rodríguez-Prieto, I. ; Amador-Álvarez, A. ; Henrich, K.-O. ; Pascual-Vaca, D. ; Okonechnikov, K. ; Rivas, E. ; Westermann, F. ; Pardal, R. ; Vega, F. M.
Identification of VRK1 as a New Neuroblastoma Tumor Progression Marker Regulating Cell Proliferation.
Cancers 12(11), 3465 (2020) [10.3390/cancers12113465]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Hawkins, C. ; Pfister, S. ; Jones, D. T. W. ; Shah, N. N. ; Gilbertson, R. J. ; Sweet-Cordero, E. A. ; Dyer, M. A. ; Mossé, Y. P. ; Haber, M. ; DuBois, S. G.
Advances and Challenges in Pediatric and Childhood Cancers.
Cancer cell 38(4), 429 - 432 (2020) [10.1016/j.ccell.2020.09.013]2020 BibTeX | EndNote: XML, Text | RIS

Kumar, V. ; Agrawal, R. ; Pandey, A. ; Kopf, S. ; Hoeffgen, M. ; Kaymak, S. ; Bandapalli, O. R. ; Gorbunova, V. ; Seluanov, A. ; Mall, M. A. ; Herzig, S. ; Nawroth, P. P.
Compromised DNA repair is responsible for diabetes-associated fibrosis.
The EMBO journal 39(11), e103477 (2020) [10.15252/embj.2019103477]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Joshi, P. K. (First author) ; Skromne, I.
A theoretical model of neural maturation in the developing chick spinal cord.
PLOS ONE 15(12), e0244219 - (2020) [10.1371/journal.pone.0244219]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Mayr, L. ; Guntner, A. S. ; Madlener, S. ; Schmook, M. T. ; Peyrl, A. ; Azizi, A. A. ; Dieckmann, K. ; Reisinger, D. ; Stepien, N. M. ; Schramm, K. ; Laemmerer, A. ; Jones, D. T. W. ; Ecker, J. ; Sahm, F. ; Milde, T. ; Pajtler, K. W. ; Blattner-Johnson, M. ; Strbac, M. ; Dorfer, C. ; Czech, T. ; Kirchhofer, D. ; Gabler, L. ; Berger, W. ; Haberler, C. ; Müllauer, L. ; Buchberger, W. ; Slavc, I. ; Lötsch-Gojo, D. ; Gojo, J. (Last author)
Cerebrospinal Fluid Penetration and Combination Therapy of Entrectinib for Disseminated ROS1/NTRK-Fusion Positive Pediatric High-Grade Glioma
Journal of Personalized Medicine 10(4), 290 (2020) [10.3390/jpm10040290]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Mayr, L. ; Gojo, J. ; Peyrl, A. ; Azizi, A. A. ; Stepien, N. M. ; Pletschko, T. ; Czech, T. ; Dorfer, C. ; Lambo, S. ; Dieckmann, K. ; Haberler, C. ; Kool, M. ; Slavc, I.
Potential Importance of Early Focal Radiotherapy Following Gross Total Resection for Long-Term Survival in Children With Embryonal Tumors With Multilayered Rosettes.
Frontiers in oncology 10, 584681 (2020) [10.3389/fonc.2020.584681.]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Zhang, Y. ; Chen, F. ; Fonseca, N. A. ; He, Y. ; Fujita, M. ; Nakagawa, H. ; Zhang, Z. ; Brazma, A. ; PCAWGTranscriptomeWorkingGroup ; PCAWGStructuralVariationWorkingGroup ; Creighton, C. J. ; PCAWGConsortium
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Nature Communications 11(1), 736 (2020) [10.1038/s41467-019-13885-w]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Alexandrov, L. B. ; Kim, J. ; Haradhvala, N. J. ; Huang, M. N. ; Tian Ng, A. W. ; Wu, Y. ; Boot, A. ; Covington, K. R. ; Gordenin, D. A. ; Bergstrom, E. N. ; Islam, S. M. A. ; Lopez-Bigas, N. ; Klimczak, L. J. ; McPherson, J. R. ; Morganella, S. ; Sabarinathan, R. ; Wheeler, D. A. ; Mustonen, V. ; PCAWGMutationalSignaturesWorkingGroup ; Getz, G. ; Rozen, S. G. ; Stratton, M. R. ; PCAWGConsortium
The repertoire of mutational signatures in human cancer.
Nature <London> 578(7793), 94 - 101 (2020) [10.1038/s41586-020-1943-3]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Paczkowska, M. ; Barenboim, J. ; Sintupisut, N. ; Fox, N. S. ; Zhu, H. ; Abd-Rabbo, D. ; Mee, M. W. ; Boutros, P. C. ; Drivers, P. ; FunctionalInterpretationWorkingGroup ; Reimand, J. ; PCAWGConsortium
Integrative pathway enrichment analysis of multivariate omics data.
Nature Communications 11(1), 735 (2020) [10.1038/s41467-019-13983-9]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Shuai, S. ; PCAWGDrivers ; FunctionalInterpretationWorkingGroup ; Gallinger, S. ; Stein, L. ; PCAWGConsortium
Combined burden and functional impact tests for cancer driver discovery using DriverPower.
Nature Communications 11(1), 734 (2020) [10.1038/s41467-019-13929-1]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Bhandari, V. ; Li, C. H. ; Bristow, R. G. ; Boutros, P. C. ; PCAWGConsortium
Divergent mutational processes distinguish hypoxic and normoxic tumours.
Nature Communications 11(1), 737 (2020) [10.1038/s41467-019-14052-x]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Rubanova, Y. ; Shi, R. ; Harrigan, C. F. ; Li, R. ; Wintersinger, J. ; Sahin, N. ; Deshwar, A. ; PCAWGEvolution ; Group, H. W. ; Morris, Q. ; PCAWGConsortium
Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig.
Nature Communications 11(1), 731 (2020) [10.1038/s41467-020-14352-7]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Reyna, M. A. ; Haan, D. ; Paczkowska, M. ; Verbeke, L. P. C. ; Vazquez, M. ; Kahraman, A. ; Pulido-Tamayo, S. ; Barenboim, J. ; Wadi, L. ; Dhingra, P. ; Shrestha, R. ; Getz, G. ; Lawrence, M. S. ; Pedersen, J. S. ; Rubin, M. A. ; Wheeler, D. A. ; Brunak, S. ; Izarzugaza, J. M. G. ; Khurana, E. ; Marchal, K. ; von Mering, C. ; Sahinalp, S. C. ; Valencia, A. ; Drivers, P. ; FunctionalInterpretationWorkingGroup ; Reimand, J. ; Stuart, J. M. ; Raphael, B. J. ; PCAWGConsortium
Pathway and network analysis of more than 2500 whole cancer genomes.
Nature Communications 11(1), 729 (2020) [10.1038/s41467-020-14367-0]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Jiao, W. ; Atwal, G. ; Polak, P. ; Karlic, R. ; Cuppen, E. ; PCAWGTumorSubtypesClinicalTranslationWorkingGroup ; Danyi, A. ; de Ridder, J. ; van Herpen, C. ; Lolkema, M. P. ; Steeghs, N. ; Getz, G. ; Morris, Q. ; Stein, L. D. ; PCAWGConsortium
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.
Nature Communications 11(1), 728 (2020) [10.1038/s41467-019-13825-8]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Cmero, M. ; Yuan, K. ; Ong, C. S. ; Schröder, J. ; PCAWG, E. ; Heterogeneity Working, G. ; Corcoran, N. M. ; Papenfuss, T. ; Hovens, C. M. ; Markowetz, F. ; Macintyre, G. ; PCAWGConsortium
Inferring structural variant cancer cell fraction.
Nature Communications 11(1), 730 (2020) [10.1038/s41467-020-14351-8]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Rheinbay, E. ; Nielsen, M. M. ; Abascal, F. ; et al
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
Nature <London> 578(7793), 102 - 111 (2020) [10.1038/s41586-020-1965-x]2020 BibTeX | EndNote: XML, Text | RIS

powered by webEdition CMS