Research
- Research Topics
- Cell Biology and Tumor Biology
- Stem Cells and Cancer
- Inflammatory Stress in Stem Cells
- Experimental Hematology
- Molecular Embryology
- Signal Transduction and Growth Control
- Epigenetics
- Redox Regulation
- Vascular Oncology and Metastasis
- Clinical Neurobiology
- Molecular Neurogenetics
- Chaperones and Proteases
- Vascular Signaling and Cancer
- Molecular Neurobiology
- Mechanisms Regulating Gene Expression
- Molecular Biology of Centrosomes and Cilia
- Dermato-Oncology
- Pediatric Leukemia
- Molecular Hematology - Oncology
- Cancer Progression and Metastasis
- Metastatic Niches
- Molecular Leukemogenesis
- DNA Repair Mechanisms and Cancer
- Neuronal Signaling and Morphogenesis
- Cell Signaling and Metabolism
- Cell Fate Engineering and Disease Modeling
- Cancer Drug Development
- Cell Morphogenesis and Signal Transduction
- Tumour Metabolism and Microenvironment
- Helmholtz Professorship Cell Biology
- Functional and Structural Genomics
- Molecular Genome Analysis
- Molecular Genetics
- Pediatric Neurooncology
- Cancer Genome Research
- Chromatin Networks
- Functional Genome Analysis
- Theoretical Systems Biology
- Neuroblastoma Genomics
- Signaling and Functional Genomics
- Signal Transduction in Cancer and Metabolism
- RNA Biology and Cancer
- Systems Biology of Signal Transduction
- Molecular thoracic Oncology
- Proteomics of Stem Cells and Cancer
- Computational Genomics and System Genetics
- Regulatory Genomics and Cancer Evolution
- Applied Functional Genomics
- Applied Bioinformatics
- Translational Medical Oncology
- Cancer Epigenomics
- Translational Pediatric Sarcoma Research
- Neuropathology
- Pediatric Oncology
- Neurooncology
- Somatic Evolution and Early Detection
- Translational Control and Metabolism
- Pediatric Glioma Research
- Soft-Tissue Sarcoma
- Precision Sarcoma Research
- Neural Stem Cell Genome Integrity in Brain Development and Diseases
- Mechanisms of Leukemogenesis
- Genome Instability in Tumors
- Developmental Origins of Pediatric Cancer
- Brain Tumor Translational Targets
- Brain Cancer Metabolism
- Translational Functional Cancer Genomics
- SPRINT
- Cancer Risk Factors and Prevention
- Cancer Epidemiology
- Biostatistics
- Clinical Epidemiology and Aging Research
- Health Economics
- Physical Activity, Prevention and Cancer
- Preventive Oncology
- Digital Biomarkers for Oncology
- Genomic Epidemiology
- Cancer Survivorship
- Molecular Epidemiology
- Immunology and Cancer
- Cellular Immunology
- Molecular Oncology of Gastrointestinal Tumors
- Translational Immunotherapy
- B Cell Immunology
- Immune Diversity
- Structural Biology of Infection and Immunity
- Applied Tumor-Immunity
- Neuroimmunology and Brain Tumor Immunology
- T Cell Metabolism
- Adaptive Immunity and Lymphoma
- Immune Regulation in Cancer
- GMP & T Cell Therapy
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- Radiology
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- Computational Radiology Research Group
- Contrast Agents In Radiology Research Group
- Neuro-Oncologic Imaging Research Group
- Radiological Early Response Assessment Of Modern Cancer Therapies
- Imaging In Monoclonal Plasma Cell Disorders
- 7 Tesla MRI - Novel Imaging Biomarkers
- Functional Imaging
- Visualization And Forensic Imaging
- PET/MRI
- Dual- and Multienergy CT
- Radiomics Research Group
- Prostate Research Group
- Breast Imaging Research Group
- Bone marrow
- Musculoskeletal Imaging
- Staff
- Patients
- Research
- Medical Physics in Radiology
- X-Ray Imaging and Computed Tomography
- Medical Informatics for Translational Oncology
- Federated Information Systems
- Medical Physics in Radiation Oncology
- Biomedical Physics in Radiation Oncology
- Computer Assisted Medical Interventions
- Medical Image Computing
- Radiooncology - Radiobiology
- Radiation Oncology
- Molecular Radiooncology
- Nuclear Medicine
- Medical Imaging and Radiology - Cancer Prevention
- Molecular Biology of Systemic Radiotherapy
- Translational Radiation Oncology
- Molecular Mechanisms of Head and Neck Tumors
- Radiology
- Infection, Inflammation and Cancer
- Tumor Virology
- Viral Transformation Mechanisms
- Pathogenesis of Virus-Associated Tumors
- Applied Tumor Biology
- Virotherapy
- Virus-associated Carcinogenesis
- Chronic Inflammation and Cancer
- Microbiome and Cancer
- Cell Plasticity and Epigenetic Remodeling
- Cellular Polarity and Viral Infection
- Noroviruses
- Laboratory of Oncolytic Virus Immuno-Therapeutics
- Infections and Cancer Epidemiology
- Tumorvirus-specific Vaccination Strategies
- Mammalian Cell Cycle Control Mechanisms
- Molecular Therapy of Virus-Associated Cancers
- Immunotherapy and Immunoprevention - Molecular Vaccine Design
- DNA Vectors
- Episomal-Persistent DNA in Cancer- and Chronic Diseases
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- Cell Biology and Tumor Biology
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- 20th Anniversary Publication
- Flyer - The Cancer Cooperation Program
- List Publications 1976-2004
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- Cooperations with industrial companies
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- Cross Program Topic RNA@DKFZ
- Cross Program Topic Epigenetics@dkfz
- Cross Program Topic Single Cell Sequencing
- WHO Collaborating Centers
- DKFZ Site Dresden
Nika Vučković
PhD Student

© dkfz.de
Phone: +49 6221 42 3822
Contact
Scientific CV
Since July 2020
PhD student, Immunotherapy and Immunoprevention / Molecular Vaccine Design, DKFZ & DZIF, Heidelberg
Mar 2018 – Dec 2018
Master´s thesis research at University of Toronto, Toronto, Canada
Aug 2017 – Jan 2018
Erasmus exchange to Chalmers University of Technology, Gothenburg, Sweden
2016 – 2019
MSc Molecular Biology, University of Zagreb, Croatia
2012 – 2016
BSc Molecular Biology, University of Zagreb, Croatia
Research project
Identification of HLA-presented HPV epitopes on cervical intraepithelial neoplasia (CIN) cells for therapeutic vaccine design
Cervical cancer is caused by persistent infection with high-risk human papillomaviruses (HPV). Virtually every sexually active individual contracts a high-risk HPV infection over their lifetime, with most infections eradicated by the immune system on the strength of an effective T-cell response. However, by dysregulating the antigen processing machinery (APM), HPV interferes with T-cell recognition of infected/transformed cells. The Riemer lab has shown that such dysregulation increases as the tumor stage progresses, therefore it is plausible that more HPV epitopes are HLA-presented on HPV-positive cells in precursor lesions (such as cervical intraepithelial neoplasia; CIN) than in fully developed cancer. Moreover, the microenvironment in CIN lesions is less immunosuppressive so therapeutic vaccination in this setting is promising. The aim of this project is to identify and validate HPV16-derived T-cell epitopes presented on CIN cells with the goal of defining a set of epitopes for an efficacious therapeutic HPV vaccine.