Publications 1999

Benner A. Ein Vergleich von SAS und S-Plus. In: Proceedings zur 3.KSFE 25./26.Febr. 1999. Univ.Heidelberg, (ed), Heidelberg: (1999).

Deichmann M., Benner A., Bock M., Jäckel A., Uhl K., Waldmann V., Näher H. S100-beta , melanoma-inhibiting activity, and lactate dehydrogenase discriminate progressive from non-progressive American Joint Committee on Cancer stage IV melanoma. J. Clin. Oncol. 17 (6): 1891-1896 (1999).

Edler L., Benner A., Rittgen W., Kopp-Schneider A. Biometrische Versuchsplanung und Fallzahlberechnung. Techn.Rep. Nr.99/1, ZE Biostatistik, Heidelberg: DKFZ (1999).

Edler L.Uncertainty in biomonitoring and kinetic modeling. In: Uncertainty in the risk assessment of environmental and occupational hazards. vol.895 Bailar J.C., Bailer A.J. (eds), Uncertainty in the risk assessment of environmental and occupational hazards. An international workshop. Bailer A.J., Maltoni C., Bailar J.C.I., Belpoggi F., Brazier J.V., Soffritti M. Ann.N.Y.Acad.Sci. pp.80-101 (1999).

Edler L.Discussion of the invited papers of session IPM 54: Optimal experimental design and computational methods in industrial applications. In: Bull.Int.Stat.Inst. ISI 52nd Session, Book 3. pp.151-154 (1999).

Edler L., Grassmann J. Protein fold class prediction is a new field for statistical classification and regression. In: Statistics in molecular biology and genetics. Seillier-Moiseiwitsch F. (ed), Lecture Notes-Monograph Series. Barbour A.A., Newton J., Ruppert D. Inst. Math. Stat. & Am. Math. Soc. pp.288-313 (1999).

Edler L., Pilz L., Pötschke-Langer M. On the prevalence of smoking among young school children and its association with risk behavior and health risks. In: Bull.Int.Stat.Inst. ISI 52nd Session Book 1. pp.293-294 (1999).

Frei E., Gilberg F., Schröder M., Breuer A., Edler L., Wiessler M. Analysis of the inhibition of n-nitroso-dimethylamine acitivation in the liver by n-nitro-dimethylamine using a new non-linear statistical method. Carcinogen. 20 (3): 459-464 (1999).

Friedrich G., Edler L.Die neue Version der Common Toxicity Criteria. Fortschritt in der Dokumentation unerwünschter Ereignisse in klinischen onkologischen Studien? In: Gesundheitspolitischer Strukturwandel: Herausforderung für die medizinische Dokumentation? 6. Fachtagung des Deutschen Verbandes Medizinischer Dokumentare, Ludwigshafen. Wurzinger S., Walter-Jung B. (eds), pp.161-166 (1999).

Frühauf S., Schmitt K., Veldwijk M.R., Topaly J., Benner A., Zeller W.J., Ho A.D., Haas R. Peripheral blood progenitor cell (PBPC) counts during steady-state haematopoiesis the estimation of the yield of mobilised PBPC after granulocyte colony-stimulating factor supported cytotoxic chemotherapy: An update on 100 patients. Brit. J. Haematol. 105: 786-794 (1999).

Gilberg F., Urfer W., Edler L. Heteroscedastic nonlinear regression models with random effects and their application to enzyme kinetic data. Biom. J. 41: 543-557 (1999).

Goldschmidt H., Hegenbart U., Hohaus S., Benner A., Wannenmacher M., Haas R., Ho A.D. High-dose Melphalan (HD-Mel) plus total-body irradiation (TBI) induces higher nonhematological toxicity without improving remission status. Bone Marrow Transplant. 23: 441(1999). (Abstract)

Grassmann J., Reczko M., Suhai S., Edler L.Protein fold class prediction. New methods of statistical classification. In: Proceedings of the ISMB99, Heidelberg, August 6-10, 1999. Menlo Park, California, USA: AAAI Press, pp.106-112 (1999).

Hartung G., Stehle G., Sinn H., Wunder A., Schrenk H.H., Heeger S., Kränzle M., Edler L., Frei E., Fiebig H.H., Heene D.L., Maier-Borst W., Queisser W. Phase I trial of methotrexate-albumin in a weekly intravenous bolus regimen in cancer patients. Clin. Cancer Res. 5: 753-759 (1999).

Kairat A., Beerheide W., Zhou G., Tang Z.Y., Edler L., Schröder C.H. Truncated hepatitis B virus RNA in human hepatocellular carcinoma: Its representation in patients with advancing age. Intervirol. 42 (4): 228-237 (1999).

Kiel K., Moos M., Cremer F.W., Ehrbrecht E., Benner A., Hegenbart U., Haas R., Ko Y., Ho A.D., Goldschmidt H. Pretreatment with alkylating agents predicts for tumor cell content and CD34+ stem cell yield in leukapheresis products of patients with multiple myeloma. Bone Marrow Transplant. 23: 443(1999). (Abstract)

Klaes R., Ridder R., Schäfer U., Benner A., Knebel-Doeberitz M.v. No evidence for p53 allele-specific predisposition in human papillomavirus-associated cervical cancer. J. Mol. Med. 77: 299-302 (1999).

Kone-Paut I., Geisler I., Wechsler B., Ozen S., Ozdogan H., Rozenbaum M., Touitou I. Familial aggregation in Behcet's disease: High frequency in siblings and parents of pediatric probands. J. Pediat. 135 (1): 89-93 (1999).

Kösters R., Ridder R., Kopp-Schneider A., Betts D., Adams V., Niggli F., Briner J., Knebel-Doeberitz M.v. Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumors. Cancer Res. 59 (16): 3880-3882 (1999).

Lutz W.K., Kopp-Schneider A. A threshold dose-response for tumor induction by genotoxic carcinogens modeled via cell-cycle delay. Toxicol. Sci. 49 (1): 110-115 (1999).

Mechtersheimer G., Otano-Joos M., Ohl S., Benner A., Lehnert T., Willeke F., Möller P., Otto H.F., Lichter P., Joos S. Analysis of chromosomal imbalances in sporadic and NF1-associated peripheral nerve sheath tumors by comparative genomic hybridization. Genes, Chromosomes & Cancer 25: 362-369 (1999).

Mross K.B., Scheulen M.E., Manegold C., Westerhausen M., Edler L., Becher R. Phase II Study with Interferon alpha-2a and 13-cis-retinoic acid in patients with metastatic renal cell carcinoma. Onkol. 22: 412-415 (1999).

Portier C.J., Edler L., Jung D., Needham L., Masten S.A., Parham F., Lucier G. Half-lives and body burdens for dioxin and dioxin-like compounds in humans estimated from an occupational cohort in Germany. Organohalogen Comp. 42: 129-137 (1999).

Rittgen W., Volm M. The identification of an optimal set of prognostic factors in cancer therapy. In: Proc. IASTED 18. Int.Symp. Hamza M.H. (ed), Anaheim: Acta Press, pp.601-604 (1999).

Rojas M., Cascorbi I., Alexandrov K., Kriek E., Auburtin G., Mayer L., Kopp-Schneider A., Roots I., Bartsch H. Polymorphism of CYP1A1, GSTM1 and GSTT1 modulates BPDE-DNA adduct levels in human WBC. J. Cancer Res. Clin. Oncol. 125: S34-(K30) (1999). (Abstract)

Schäfer K., Müller M., Faath S., Henn A., Osen W., Zentgraf H., Benner A., Gissmann L., Jochmus I. Immune response to human papillomavirus 16 L1E7 chimeric virus-like particles: Induction of cytotoxic T cells and specific tumor protection. Int. J. Cancer 81 (6): 881-888 (1999).

Schmezer P., Rajaee-Behbahani N., Risch A., Thiel S., Rittgen W., Drings P., Dienemann H., Kayser K., Schulz V., Bartsch H. Mutagen sensitivity and DNA repair capacity as risk factors for lung cancer. J. Cancer Res. Clin. Oncol. 125: S1-(ML2) (1999). (Abstract)

Stilgenbauer S., Bullinger L., Benner A., Wildenberger K., Bentz M., Döhner K., Ho A.D., Lichter P., Döhner H. Incidence and clinical significance of 6q deletions in B-cell chronic lymphocytic leukemia. Leukem. 13 (9): 1331-1334 (1999).

Victor N., Blettner M., Edler L., Haux R., Knaup-Gregori P., Pritsch M., Wahrendorf J., Windeler J., Ziegler S. Medical informatics, biostatistics and epidemiology for efficient health care and medical research. 85: Medizinische Informatik, Biometrie und Epidemiologie. Überla K., Rienhoff O., Victor N. München: Medizin&Wissen, (1999).