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Research

Dr. David Brocks

Position:

Postdoc

German-Israeli Helmholtz Research School in Cancer Biology

Thesis topic: Tumor heterogeneity

Publication list:

Lipka DB, Wang Q, ... Brocks D, ... Trumpp A, Milsom MD, Plass C. Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing. Cell Cycle. 2014; 13(22): 3476-87. Abstract
Oakes CC, Claus R, Gu L, ... Brocks D, ... Zenz T, Plass C. Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia. Cancer Discov. 2014; 4(3): 348-61. Abstract
Bierhoff H, Dammert MA, Brocks D, Dambacher S, Schotta G, Grummt I. Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencing. Mol Cell. 2014; 54(4): 675-82. Abstract
Brocks D, Assenov Y, ... Gerhäuser C, Plass C; ICGC Early Onset Prostate Cancer Project. Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer. Cell Rep. 2014; 8(3): 798-806. Abstract
Cabezas-Wallscheid N, ... Brocks D, ... Milsom MD, Plass C, Krijgsveld J, Trumpp A. Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis. Cell Stem Cell. 2014;15(4): 507-22. Abstract
Brocks D. Musical patterns for comparative epigenomics. Clin Epigenetics. 2015; 7(1): 94. Abstract
Walter D, ... Brocks D, ... Trumpp A, Milsom MD. Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells. Nature. 2015; 520(7548): 549-52. Abstract