Epigenomics of hormone-driven cancers

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Dr. Clarissa Gerhäuser

Team Leader Epigenomics of hormone-driven Cancer

Major Research Direction

In the Epigenomics of hormone-driven cancers group, current projects focus on 

  • The role of 5-hydroxymethylation in cancer
  • Profiling DNA hydroxy-/methylation and chromatin accessibility
  • Epigenetic mechanisms in cancer and metastasis development, with a focus on breast and prostate cancer
  • Developing biomarkers for endogenous endocrine resistance in breast cancer
  • Characterizing the enhancer methylome in prostate cancer
  • The pan-prostate cancer methylome landscape
  • cfDNA and liquid biopsies for early cancer detection

Ongoing Projects

ICGC Project on Early Onset Prostate Cancer
The role of enhancer elements in prostate cancer
Molecular determinants of primary endocrine resistance in luminal breast cancer
EpiPROPER
Past Projects

Members

  • A woman with shoulder-length blonde hair smiles warmly at the camera. She wears glasses and is dressed in a light jacket over a white shirt with a colorful scarf. Lush green foliage serves as the background.

    Dr. Clarissa Gerhäuser

    Team Leader Epigenomics of hormone-driven Cancer

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    Nan Zhang

    PhD Student

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    Maxime de Vrieze

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    Stefan Altendorfer

    PhD student

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    Jessica Heilmann

    Technician

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A woman with shoulder-length blonde hair smiles warmly at the camera. She wears glasses and is dressed in a light jacket over a white shirt with a colorful scarf. Lush green foliage serves as the background.

Dr. Clarissa Gerhäuser

Team Leader Epigenomics of hormone-driven Cancer
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