Epigenomics of hormone-driven cancers
Major Research Direction
In the Cancer Chemoprevention and Epigenomcs group, current projects focus on
- The role of 5-hydroxymethylation in human adipogenesis
- Profiling DNA hydroxy-/methylation and chromatin accessibility in human intervention studies
- Epigenetic mechanisms in cancer and metastasis development, with a focus on breast and prostate cancer
- Developing biomarkers for endogenous endocrine resistance in breast cancer
- Characterizing the enhancer methylome in prostate cancer
- The pan-prostate cancer methylome landscape