MR image encoding

The limited lifetime of the hyperpolarized spin state requires special strategies when recording MRI data. In the CAVKA method, for example, the magnetization of the hyperpolarized spins is divided into segments of equal size and only used for the most necessary information of the image contrast. The measurement time can thus be reduced by a factor of 20.

The image presents a comparison of two sets of visual data: one showing fully sampled images with no averaging and the other with 16 averages of a reference image. It illustrates how increasing the signal enhances clarity while decreasing noise, highlighted through visual representations and a schematic diagram.
The image shows two MRI scans of a mouse's head. The left scan displays a standard hydrogen MRI, while the right reveals a color-enhanced continuous flow xenon MRI, indicating gas escaping from a ventilation mask. Labels provide technical details about the imaging parameters.

CAVKA stands for "Combined Approach of Varaible Flip Angle (VFA) and Keyhole Acquisition" and combines two approaches that are used in other contexts to make optimal use of the magnetization of hyperpolarized spins and to acquire MRI data more quickly. The methods will initially be tested for the Xe exchange behavior of various biosensors and will then be used in preclinical studies.

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