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Last update: : 31.01.2025
The role of altered lipid metabolism in cancer A specific focus of the work of the division is the analysis of processes regulating lipid metabolism downstream of the sterol regulatory element…
Last update: : 31.01.2025
Identification of selective metabolic vulnerabilities A major activity of the division is the identification of metabolic vulnerabilities in cancer cells. Aerobic glycolysis, also known as the…
Last update: : 31.01.2025
Regulation of ferroptosis at the intersection of lipid metabolism and cell death Ferroptosis, a form of regulated cell death triggered by accumulation of toxic lipid hydroperoxides, is under…
Last update: : 31.01.2025
Metabolic cross-talk within the tumour microenvironment The metabolic microenvironment of tumours is also determined by the complex heterotypic interactions between different cell types within the…
Last update: : 31.01.2025
← Back to Team - Former Lab Members Research Project Development of an optimal vaccination approach for minimal epitope-based therapeutic vaccines against HPV-induced malignancies in a…
Last update: : 31.01.2025
← Back to Team - Former Lab Members Research Project Development of optimal formulation and delivery systems for epitope-based therapeutic HPV vaccines Therapeutic vaccination with…
Last update: : 31.01.2025
← Back to Team - Former Lab Members Research Project Identification of HPV16 T cell epitopes for HLA-A3, HLA-A11 and HLA-A24 The viral oncoproteins E6 and E7 are consistently expressed…
Last update: : 31.01.2025
← Back to Team - Former Lab Members Research Project Identification of promiscuous HLA class II-restricted human papillomavirus type 16 E2-, E5-, E6- and E7-derived CD4+ helper T cell…
Last update: : 31.01.2025
← Back to Team - Former Lab Members Research Project Mass spectrometry-based identification of HPV16 target epitopes for therapeutic vaccine design The overall aim of the group is to…
Last update: : 31.01.2025
Our Research Metabolic reprogramming is an emerging hallmark of cancer. Altered metabolic activity in cancer cells drives the production of macromolecules for rapid proliferation and allows cancer…