Research
- Research Topics
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- Epigenetics
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- Signal Transduction in Cancer and Metabolism
- RNA Biology and Cancer
- Systems Biology of Signal Transduction
- Molecular thoracic Oncology
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- Soft-Tissue Sarcoma
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- Brain Mosaicism and Tumorigenesis
- Mechanisms of Genome Control
- Translational Gastrointestinal Oncology and Preclinical Models
- Translational Lymphoma Research
- Mechanisms of Leukemogenesis
- Genome Instability in Tumors
- Developmental Origins of Pediatric Cancer
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- Medical Physics in Radiology
- X-Ray Imaging and Computed Tomography
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- Medical Physics in Radiation Oncology
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- Cell Plasticity and Epigenetic Remodeling
- Experimental Hepatology, Inflammation and Cancer
- Infections and Cancer Epidemiology
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- Cell Biology and Tumor Biology
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Biographical Sketch
Prof. Dr. Marc Kachelrieß
Marc Kachelrieß was born in 1969 in Nürnberg, Germany. In 1989 he began to study physics with a focus on theoretical particle physics. His diploma thesis was entitled 'Meson exchange currents in light nuclei. He received his diploma at the Friedrich-Alexander-University of Erlangen-Nürnberg in 1995.
Then, Marc Kachelrieß started his dissertation at the Institute of Medical Physics (IMP). He developed reconstruction algorithms to reduce metal artifacts in x-ray computed tomography (CT). In parallel, Marc Kachelrieß introduced a new method that allows to generate motion-free images of the human heart using standard CT data. Thereby the clinical feasibility of retrospective electrocardiogram-correlated image reconstruction from CT data was proven. This method is now in world-wide use in clinical CT scanners. Marc Kachelrieß received his Ph.D. at the IMP in 1998.
Since then, he focuses on cardiac imaging and extended the approaches to future scanner generations, his research covers image reconstruction of cone-beam CT data, iterative image reconstruction, image reconstruction algorithms in general, and sophisticated calibration techniques. Marc Kachelrieß is involved in developing algorithms for automatic exposure control (AEC) for CT, algorithms for dual and multi-energy CT imaging, methods to reduce CT artifacts and patient dose reduction techniques. His work also includes the design and development of micro-CT scanner hard- and software, micro-CT pre- and post processing software and image quality opti-mization techniques. An additional focus is high performance medical imaging, using standard PC hardware, graphics processing units, cell processors and FPGA hardware, which enables real-time imaging even for highly complex algorithms in clinical routine. Marc Kachelrieß is not only active in the medical imaging field, where clinical CT scanners and C-arm CT scanners are dominating, but also in the field of non-destructive testing, luggage screening, electron beam CT, industrial CT, CT metrology, and dimensional CT.
In 2002 Marc Kachelrieß completed all post doctoral lecturing qualifications (habilitation) for Medical Physics and in 2005 he was appointed Professor of Medical Imaging at the Friedrich-Alexander-University Erlangen-Nürnberg, Germany. On the basis of his university teaching position he lectures in medical imaging technology, physics and algorithms. Since 2009 Marc Kachelrieß additionally holds an Adjunct Associate Professor position at the Department of Radiology at the University of Utah, USA. Since 2011 Marc Kachelrieß is also chairing the work group X-Ray Imaging and Computed Tomography in the department of Medical Physics in Radiology of the German Cancer Research Center (DKFZ) in Heidelberg, Germany.
Marc Kachelrieß is author or coauthor of more than 350 publications, and he is organizer of several conferences and workshops in the field of tomographic and high performance imaging.