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Publications 2023

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Reference on copy number variations in pleomorphic xanthoastrocytoma: Implications for diagnostic approach.
Free Neuropathology 4, 4-19 () [10.17879/FREENEUROPATHOLOGY-2023-5156]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T: evaluation of a modeling workflow.
Journal of neuro-oncology 165(3), 467-478 () [10.1007/s11060-023-04500-6]  GO BibTeX | EndNote: XML, Text | RIS

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Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures.
Nature Communications 14(1), 7717 () [10.1038/s41467-023-43564-w]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Prognostic significance of molecular subgroups in survival outcome for children with medulloblastoma in Malaysia
Frontiers in oncology 13, 1278611 () [10.3389/fonc.2023.1278611]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations.
Acta neuropathologica 146(6), 849-852 () [10.1007/s00401-023-02640-7]  GO BibTeX | EndNote: XML, Text | RIS

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Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics.
Acta neuropathologica 146(6), 853-856 () [10.1007/s00401-023-02638-1]  GO BibTeX | EndNote: XML, Text | RIS

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Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours.
Genome medicine 15(1), 67 () [10.1186/s13073-023-01219-x]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Mapping pediatric brain tumors to their origins in the developing cerebellum.
Neuro-Oncology 25(10), 1895-1909 () [10.1093/neuonc/noad124]  GO BibTeX | EndNote: XML, Text | RIS

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Implementation of DNA methylation array profiling in pediatric central nervous system tumors - the AIM BRAIN Project: an Australian and New Zealand Children's Haematology and Oncology (ANZCHOG) Group study.
The journal of molecular diagnostics 25(10), 709-728 () [10.1016/j.jmoldx.2023.06.013]  GO BibTeX | EndNote: XML, Text | RIS

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MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas.
Nature Communications 14(1), 4533 () [10.1038/s41467-023-40235-8]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Mitochondrial DNA mutations in Medulloblastoma.
Acta Neuropathologica Communications 11(1), 124 () [10.1186/s40478-023-01602-0]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.
Neuro-Oncology 25(12), 2273-2286 () [10.1093/neuonc/noad114]  GO BibTeX | EndNote: XML, Text | RIS

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Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORM.
JCO precision oncology 7(7), e2300015 () [10.1200/PO.23.00015]  GO BibTeX | EndNote: XML, Text | RIS

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A multi-institutional retrospective pooled outcome analysis of molecularly annotated pediatric supratentorial ZFTA-fused ependymoma.
Neuro-oncology advances 5(1), vdad057 () [10.1093/noajnl/vdad057]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Analysis of recurrence probability following radiotherapy in patients with CNS WHO grade 2 meningioma using integrated molecular-morphologic classification.
Neuro-oncology advances 5(1), vdad059 () [10.1093/noajnl/vdad059]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Group-specific cellular metabolism in Medulloblastoma.
Journal of translational medicine 21(1), 363 () [10.1186/s12967-023-04211-6]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Clinical outcome following surgical resection and radiotherapy in adult patients with pleomorphic xanthoastrocytoma as defined by DNA methylation profiling.
Neuro-oncology practice 10(3), 307 - 314 () [10.1093/nop/npad004]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.
Journal of neuro-oncology 163(1), 143-158 () [10.1007/s11060-023-04319-1]  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Nature genetics 55, 1076 () [10.1038/s41588-023-01315-z]  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer
Nature genetics 55, 1079 () [10.1038/s41588-023-01318-w]  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
Nature genetics 55, 1080 () [10.1038/s41588-023-01319-9]  GO BibTeX | EndNote: XML, Text | RIS

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Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes.
Acta neuropathologica 145(6), 829-842 () [10.1007/s00401-023-02575-z]  GO BibTeX | EndNote: XML, Text | RIS

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Evaluating preclinical evidence for clinical translation in childhood brain tumours: Guidelines from the CONNECT, PNOC, and ITCC brain networks.
Frontiers in oncology 13, 1167082 () [10.3389/fonc.2023.1167082]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients.
Neuro-Oncology 25(11), 2087-2097 () [10.1093/neuonc/noad078]  GO BibTeX | EndNote: XML, Text | RIS

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Combination Early-Phase Trials of Anticancer Agents in Children and Adolescents.
Journal of clinical oncology 41(18), 3408-3422 () [10.1200/JCO.22.02430]  GO BibTeX | EndNote: XML, Text | RIS

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Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature.
npj precision oncology 7(1), 30 () [10.1038/s41698-023-00372-1]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Genomic characterization of DICER1-associated neoplasms uncovers molecular classes.
Nature Communications 14(1), 1677 () [10.1038/s41467-023-37092-w]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Corrigendum to 'Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry' [Eur J Cancer 180 (2023) 71-84].
European journal of cancer 184, 200-201 () [10.1016/j.ejca.2023.02.024]  GO BibTeX | EndNote: XML, Text | RIS

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Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions.
Acta neuropathologica 145(5), 667-680 () [10.1007/s00401-023-02558-0]  GO BibTeX | EndNote: XML, Text | RIS

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Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.
Nature medicine 29(4), 917-926 () [10.1038/s41591-023-02255-1]  GO BibTeX | EndNote: XML, Text | RIS

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Genomic ALK alterations in primary and relapsed neuroblastoma.
British journal of cancer 128(8), 1559-1571 () [10.1038/s41416-023-02208-y]  GO BibTeX | EndNote: XML, Text | RIS

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Correction to: Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.
Acta neuropathologica 145(4), 511-514 () [10.1007/s00401-023-02538-4]  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: Pan-cancer analysis of whole genomes
Nature <London> 614, E39 () [10.1038/s41586-022-05598-w]  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: Patterns of somatic structural variation in human cancer genomes
Nature <London> 614, E38 () [10.1038/s41586-022-05597-x]  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: The repertoire of mutational signatures in human cancer
Nature <London> 614, E41 () [10.1038/s41586-022-05600-5]  GO BibTeX | EndNote: XML, Text | RIS

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Risk prediction in early childhood SHH medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than two subgroups.
Neuro-Oncology 25(8), 1518-1529 () [10.1093/neuonc/noad027]  GO BibTeX | EndNote: XML, Text | RIS

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Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers.
Nature cancer 4(2), 276-289 () [10.1038/s43018-022-00509-4]  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: Genomic basis for RNA alterations in cancer
Nature <London> 614(7948), p. E37 () [10.1038/s41586-022-05596-y]  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
Nature <London> 614(7948), p. E40 () [10.1038/s41586-022-05599-9]  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: The evolutionary history of 2,658 cancers
Nature <London> 614(7948), p. E42 () [10.1038/s41586-022-05601-4]  GO BibTeX | EndNote: XML, Text | RIS

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Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses.
Acta Neuropathologica Communications 11(1), 7 () [10.1186/s40478-023-01504-1]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry.
European journal of cancer 180, 71 - 84 () [10.1016/j.ejca.2022.11.015]  GO BibTeX | EndNote: XML, Text | RIS

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Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.
Acta neuropathologica 145(1), 97-112 () [10.1007/s00401-022-02522-4]  GO BibTeX | EndNote: XML, Text | RIS

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Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.
Acta neuropathologica 145(1), 49-69 () [10.1007/s00401-022-02516-2]  GO BibTeX | EndNote: XML, Text | RIS

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Clinical implementation of integrated molecular-morphologic risk prediction for meningioma.
Brain pathology 33(3), e13132 () [10.1111/bpa.13132]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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ERBB and P-glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P-glycoprotein.
Molecular oncology 17(1), 37-58 () [10.1002/1878-0261.13318]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.
Neuro-Oncology 25(4), 735-747 () [10.1093/neuonc/noac199]  GO BibTeX | EndNote: XML, Text | RIS

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The first-in-class ERK inhibitor ulixertinib shows promising activity in MAPK-driven pediatric low-grade glioma models.
Neuro-Oncology 25(3), 566-579 () [10.1093/neuonc/noac183]  GO BibTeX | EndNote: XML, Text | RIS

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