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Publications 2023

Deng, M. ; Hinz, F. ; Harrabi, S. ; Sturm, D. ; Sill, M. ; Korshunov, A. ; Eichkorn, T. ; Hörner-Rieber, J. ; Herfarth, K. ; Jungk, C. ; Unterberg, A. ; Pfister, S. ; Wick, W. ; von Deimling, A. ; Jones, D. ; Debus, J. ; Sahm, F. ; König, L.
Clinical outcome following surgical resection and radiotherapy in adult patients with pleomorphic xanthoastrocytoma as defined by DNA methylation profiling.
Neuro-oncology practice 10(3), 307 - 314 (2023) [10.1093/nop/npad004]2023 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Valinciute, G. (First author) ; Ecker, J. ; Selt, F. ; Hielscher, T. ; Sigaud, R. ; Ridinger, J. ; Thatikonda, V. ; Gatzweiler, C. ; Robinson, S. ; Talbot, J. ; Bernardi, F. ; Picard, D. ; Blattner-Johnson, M. ; Schmid, S. ; Jones, D. T. ; van Tilburg, C. M. ; Capper, D. ; Kool, M. ; Remke, M. ; Oehme, I. ; Pfister, S. M. ; Roussel, M. F. ; Ayrault, O. ; Witt, O. ; Milde, T. (Last author)
Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.
Journal of neuro-oncology nn, nn (2023) [10.1007/s11060-023-04319-1]2023 BibTeX | EndNote: XML, Text | RIS

Cortés-Ciriano, I. ; Lee, J. J. ; Xi, R. ; et al
Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Nature genetics nn, nn (2023) [10.1038/s41588-023-01315-z]2023 BibTeX | EndNote: XML, Text | RIS

Akdemir, K. C. ; Le, V. T. ; Chandran, S. ; et al
Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer
Nature genetics nn, nn (2023) [10.1038/s41588-023-01318-w]2023 BibTeX | EndNote: XML, Text | RIS

Rodriguez-Martin, B. ; Alvarez, E. G. ; Baez-Ortega, A. ; et al
Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
Nature genetics nn, nn (2023) [10.1038/s41588-023-01319-9]2023 BibTeX | EndNote: XML, Text | RIS

Korshunov, A. (First author) ; Okonechnikov, K. ; Schrimpf, D. ; Tonn, S. ; Mynarek, M. ; Koster, J. ; Sievers, P. ; Milde, T. ; Sahm, F. ; Jones, D. ; von Deimling, A. ; Pfister, S. ; Kool, M. (Last author)
Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes.
Acta neuropathologica 145(6), 829-842 (2023) [10.1007/s00401-023-02575-z]2023 BibTeX | EndNote: XML, Text | RIS

Jones, C. ; Straathof, K. ; Fouladi, M. ; Hargrave, D. ; Prados, M. ; Resnick, A. ; Doz, F. ; Jones, D. T. W. ; Mueller, S.
Evaluating preclinical evidence for clinical translation in childhood brain tumours: Guidelines from the CONNECT, PNOC, and ITCC brain networks.
Frontiers in oncology 13, 1167082 (2023) [10.3389/fonc.2023.1167082]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Hardin, E. C. (First author) ; Schmid, S. ; Sommerkamp, A. ; Bodden, C. ; Heipertz, A.-E. ; Sievers, P. ; Wittmann, A. ; Milde, T. ; Pfister, S. ; von Deimling, A. ; Horn, S. ; Herz, N. A. ; Simon, M. ; Perera, A. A. ; Azizi, A. ; Cruz, O. ; Curry, S. ; Van Damme, A. ; Garami, M. ; Hargrave, D. ; Kattamis, A. ; Kotnik, B. F. ; Lähteenmäki, P. ; Scheinemann, K. ; Schouten-van Meeteren, A. Y. N. ; Sehested, A. ; Viscardi, E. ; Wormdal, O. M. ; Zapotocky, M. ; Ziegler, D. S. ; Koch, A. ; Driever, P. H. ; Witt, O. ; Capper, D. ; Sahm, F. ; Jones, D. ; van Tilburg, C. M. (Last author)
LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients.
Neuro-Oncology nn, nn (2023) [10.1093/neuonc/noad078]2023 BibTeX | EndNote: XML, Text | RIS

Moreno, L. ; DuBois, S. G. ; Glade Bender, J. ; Mauguen, A. ; Bird, N. ; Buenger, V. ; Casanova, M. ; Doz, F. ; Fox, E. ; Gore, L. ; Hawkins, D. S. ; Izraeli, S. ; Jones, D. ; Kearns, P. R. ; Molenaar, J. J. ; Nysom, K. ; Pfister, S. ; Reaman, G. ; Smith, M. ; Weigel, B. ; Vassal, G. ; Zwaan, C. M. ; Paoletti, X. ; Iasonos, A. ; Pearson, A. D. J.
Combination Early-Phase Trials of Anticancer Agents in Children and Adolescents.
Journal of clinical oncology nn, nn (2023) [10.1200/JCO.22.02430]2023 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Sill, M. ; Schrimpf, D. ; Abdullaev, Z. ; Donson, A. M. ; Lake, J. A. ; Friedel, D. ; Scheie, D. ; Tynninen, O. ; Rauramaa, T. ; Vepsäläinen, K. L. ; Samuel, D. ; Chapman, R. ; Grundy, R. G. ; Pajtler, K. W. ; Tauziède-Espariat, A. ; Métais, A. ; Varlet, P. ; Snuderl, M. ; Jacques, T. S. ; Aldape, K. ; Reuss, D. E. ; Korshunov, A. ; Wick, W. ; Pfister, S. M. ; von Deimling, A. ; Sahm, F. (Last author) ; Jones, D. (Last author)
Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature.
npj precision oncology 7(1), 30 (2023) [10.1038/s41698-023-00372-1]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Kommoss, F. K. F. ; Chong, A.-S. ; Chong, A.-L. ; Pfaff, E. ; Jones, D. ; Hiemcke-Jiwa, L. S. ; Kester, L. A. ; Flucke, U. ; Gessler, M. ; Schrimpf, D. ; Sahm, F. ; Clarke, B. A. ; Stewart, C. J. R. ; Wang, Y. ; Gilks, C. B. ; Kommoss, F. ; Huntsman, D. G. ; Schüller, U. ; Koelsche, C. ; Glenn McCluggage, W. ; von Deimling, A. (Last author) ; Foulkes, W. D.
Genomic characterization of DICER1-associated neoplasms uncovers molecular classes.
Nature Communications 14(1), 1677 (2023) [10.1038/s41467-023-37092-w]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Ecker, J. (First author) ; Selt, F. ; Sturm, D. ; Sill, M. ; Korshunov, A. ; Hirsch, S. ; Capper, D. ; Dikow, N. ; Sutter, C. ; Müller, C. ; Sigaud, R. ; Eggert, A. ; Simon, T. ; Niehues, T. ; von Deimling, A. ; Pajtler, K. ; van Tilburg, C. M. ; Jones, D. ; Sahm, F. ; Pfister, S. ; Witt, O. ; Milde, T. (Last author)
Corrigendum to 'Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry' [Eur J Cancer 180 (2023) 71-84].
European journal of cancer nn, nn (2023) [10.1016/j.ejca.2023.02.024]2023 BibTeX | EndNote: XML, Text | RIS

Bogumil, H. (First author) ; Sill, M. ; Schrimpf, D. ; et al
Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions.
Acta neuropathologica nn, nn (2023) [10.1007/s00401-023-02558-0]2023 BibTeX | EndNote: XML, Text | RIS

Sturm, D. (First author) ; Capper, D. ; Andreiuolo, F. ; et al
Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.
Nature medicine nn, nn (2023) [10.1038/s41591-023-02255-1]2023 BibTeX | EndNote: XML, Text | RIS

Rosswog, C. ; Fassunke, J. ; Ernst, A. ; Schömig-Markiefka, B. ; Merkelbach-Bruse, S. ; Bartenhagen, C. ; Cartolano, M. ; Ackermann, S. ; Theissen, J. ; Blattner-Johnson, M. ; Jones, B. ; Schramm, K. ; Altmüller, J. ; Nürnberg, P. ; Ortmann, M. ; Berthold, F. ; Peifer, M. ; Büttner, R. ; Westermann, F. ; Schulte, J. H. ; Simon, T. ; Hero, B. ; Fischer, M.
Genomic ALK alterations in primary and relapsed neuroblastoma.
British journal of cancer nn, nn (2023) [10.1038/s41416-023-02208-y]2023 BibTeX | EndNote: XML, Text | RIS

Keck, M.-K. (First author) ; Sill, M. ; Wittmann, A. ; et al
Correction to: Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.
Acta neuropathologica 145(4), 511-514 (2023) [10.1007/s00401-023-02538-4]2023 BibTeX | EndNote: XML, Text | RIS

Aaltonen, L. A. ; Abascal, F. ; Abeshouse, A. ; et al
Author Correction: Pan-cancer analysis of whole genomes
Nature <London> 614, E39 (2023) [10.1038/s41586-022-05598-w]2023 BibTeX | EndNote: XML, Text | RIS

Li, Y. ; Roberts, N. D. ; Wala, J. A. ; et al
Author Correction: Patterns of somatic structural variation in human cancer genomes
Nature <London> 614, E38 (2023) [10.1038/s41586-022-05597-x]2023 BibTeX | EndNote: XML, Text | RIS

Alexandrov, L. B. ; Kim, J. ; Haradhvala, N. J. ; et al
Author Correction: The repertoire of mutational signatures in human cancer
Nature <London> 614, E41 (2023) [10.1038/s41586-022-05600-5]2023 BibTeX | EndNote: XML, Text | RIS

Tonn, S. ; Korshunov, A. ; Obrecht, D. ; Sill, M. ; Spohn, M. ; von Hoff, K. ; Milde, T. ; Pietsch, T. ; Goschzik, T. ; Bison, B. ; Juhnke, B.-O. ; Struve, N. ; Sturm, D. ; Sahm, F. ; Bockmayr, M. ; Friedrich, C. ; von Bueren, A. O. ; Gerber, N. U. ; Benesch, M. ; Jones, D. ; Kool, M. ; Wefers, A. K. ; Schüller, U. ; Pfister, S. ; Rutkowski, S. ; Mynarek, M.
Risk prediction in early childhood SHH medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than two subgroups.
Neuro-Oncology nn, nn (2023) [10.1093/neuonc/noad027]2023 BibTeX | EndNote: XML, Text | RIS

Thatikonda, V. (First author) ; Islam, S. M. A. ; Autry, R. ; Jones, B. ; Gröbner, S. ; Warsow, G. ; Hutter, B. ; Hübschmann, D. ; Fröhling, S. ; Kool, M. ; Blattner-Johnson, M. ; Jones, D. ; Alexandrov, L. B. ; Pfister, S. ; Jäger, N. (Last author)
Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers.
Nature cancer 4(2), 276-289 (2023) [10.1038/s43018-022-00509-4]2023 BibTeX | EndNote: XML, Text | RIS

Calabrese, C. ; Davidson, N. R. ; Demircio?lu, D. ; et al
Author Correction: Genomic basis for RNA alterations in cancer
Nature <London> 614(7948), p. E37 (2023) [10.1038/s41586-022-05596-y]2023 BibTeX | EndNote: XML, Text | RIS

Rheinbay, E. ; Nielsen, M. M. ; Abascal, F. ; et al
Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
Nature <London> 614(7948), p. E40 (2023) [10.1038/s41586-022-05599-9]2023 BibTeX | EndNote: XML, Text | RIS

Gerstung, M. ; Jolly, C. ; Leshchiner, I. ; et al
Author Correction: The evolutionary history of 2,658 cancers
Nature <London> 614(7948), p. E42 (2023) [10.1038/s41586-022-05601-4]2023 BibTeX | EndNote: XML, Text | RIS

Okonechnikov, K. (First author) ; Federico, A. ; Schrimpf, D. ; Sievers, P. ; Sahm, F. ; Koster, J. ; Jones, D. ; von Deimling, A. ; Pfister, S. ; Kool, M. ; Korshunov, A. (Last author)
Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses.
Acta Neuropathologica Communications 11(1), 7 (2023) [10.1186/s40478-023-01504-1]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Ecker, J. (First author) ; Selt, F. ; Sturm, D. ; Sill, M. ; Korshunov, A. ; Hirsch, S. ; Capper, D. ; Dikow, N. ; Sutter, C. ; Müller, C. ; Sigaud, R. ; Eggert, A. ; Simon, T. ; Niehues, T. ; von Deimling, A. ; Pajtler, K. W. ; van Tilburg, C. M. ; Jones, D. T. W. ; Sahm, F. ; Pfister, S. M. ; Witt, O. ; Milde, T. (Last author)
Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry.
European journal of cancer 180, 71 - 84 (2023) [10.1016/j.ejca.2022.11.015]2023 BibTeX | EndNote: XML, Text | RIS

Mynarek, M. ; Obrecht, D. ; Sill, M. ; Sturm, D. ; Kloth-Stachnau, K. ; Selt, F. ; Ecker, J. ; von Hoff, K. ; Juhnke, B.-O. ; Goschzik, T. ; Pietsch, T. ; Bockmayr, M. ; Kool, M. ; von Deimling, A. ; Witt, O. ; Schüller, U. ; Benesch, M. ; Gerber, N. U. ; Sahm, F. ; Jones, D. ; Korshunov, A. ; Pfister, S. ; Rutkowski, S. ; Milde, T. (Last author)
Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.
Acta neuropathologica 145(1), 97-112 (2023) [10.1007/s00401-022-02522-4]2023 BibTeX | EndNote: XML, Text | RIS

Keck, M.-K. (First author) ; Sill, M. ; Wittmann, A. ; et al
Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.
Acta neuropathologica 145(1), 49-69 (2023) [10.1007/s00401-022-02516-2]2023 BibTeX | EndNote: XML, Text | RIS

Hielscher, T. (First author) ; Sill, M. ; Sievers, P. ; Stichel, D. ; Brandner, S. ; Jones, D. ; von Deimling, A. ; Sahm, F. (Last author) ; Maas, S. L. N.
Clinical implementation of integrated molecular-morphologic risk prediction for meningioma.
Brain pathology 33(3), e13132 (2023) [10.1111/bpa.13132]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Rösch, L. (First author) ; Herter, S. ; Najafi, S. ; Ridinger, J. ; Peterziel, H. ; Cinatl, J. ; Jones, D. T. W. ; Michaelis, M. ; Witt, O. ; Oehme, I. (Last author)
ERBB and P-glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P-glycoprotein.
Molecular oncology 17(1), 37-58 (2023) [10.1002/1878-0261.13318]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Selt, F. (First author) ; Sigaud, R. ; Valinciute, G. ; Sievers, P. ; Zaman, J. ; Alco, C. ; Schmid, S. ; Peterziel, H. ; Tsai, J. W. ; Guiho, R. ; Martínez-Barbera, J. P. ; Pusch, S. ; Deng, J. ; Zhai, Y. ; van Tilburg, C. M. ; Schuhman, M. U. ; Damaty, A. E. L. ; Bandopadhayay, P. ; Herold-Mende, C. ; von Deimling, A. ; Pfister, S. ; Montero, J. ; Capper, D. ; Oehme, I. ; Sahm, F. ; Jones, D. ; Witt, O. ; Milde, T. (Last author)
BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.
Neuro-Oncology 25(4), 735-747 (2023) [10.1093/neuonc/noac199]2023 BibTeX | EndNote: XML, Text | RIS

Sigaud, R. (First author) ; Rösch, L. (First author) ; Gatzweiler, C. (First author) ; Benzel, J. (First author) ; von Soosten, L. (First author) ; Peterziel, H. ; Selt, F. ; Najafi, S. ; Ayhan, S. ; Gerloff, X. ; Hofmann, N. ; Büdenbender, I. ; Schmitt, L. ; Foerster, K. I. ; Burhenne, J. ; Haefeli, W. E. ; Korshunov, A. ; Sahm, F. ; van Tilburg, C. M. ; Jones, D. ; Pfister, S. ; Knoerzer, D. ; Kreider, B. L. ; Sauter, M. ; Pajtler, K. (Last author) ; Zuckermann, M. (Last author) ; Oehme, I. (Last author) ; Witt, O. (Last author) ; Milde, T. (Last author)
The first-in-class ERK inhibitor ulixertinib shows promising activity in MAPK-driven pediatric low-grade glioma models.
Neuro-Oncology 25(3), 566-579 (2023) [10.1093/neuonc/noac183]2023 BibTeX | EndNote: XML, Text | RIS

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