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Publications 2021

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Defining the Spectrum, Treatment and Outcome of Patients With Genetically Confirmed Gorlin Syndrome From the HIT-MED Cohort
Frontiers in oncology 11, 756025 () [10.3389/fonc.2021.756025]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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High-Resolution Cartography of the Transcriptome and Methylome Landscapes of Diffuse Gliomas.
Cancers 13(13), 3198 () [10.3390/cancers13133198]  GO DBCoverage   Download fulltextFulltext Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma.
PLoS Computational Biology 17(11), e1009562 - () [10.1371/journal.pcbi.1009562]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Spontaneous regression of a congenital high-grade glioma-a case report.
Neuro-oncology advances 3(1), vdab120 () [10.1093/noajnl/vdab120]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Genetic and epigenetic characterization of posterior pituitary tumors.
Acta neuropathologica 142(6), 1025-1043 () [10.1007/s00401-021-02377-1]  GO BibTeX | EndNote: XML, Text | RIS

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Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated.
Journal of clinical oncology 39(34), 3839-3852 () [10.1200/JCO.21.00784]  GO BibTeX | EndNote: XML, Text | RIS

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GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.
Acta neuropathologica 142(6), 1065-1069 () [10.1007/s00401-021-02369-1]  GO BibTeX | EndNote: XML, Text | RIS

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Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B.
Nature Communications 12(1), 5530 () [10.1038/s41467-021-25708-y]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma.
Cancers 13(17), 4476 () [10.3390/cancers13174476]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum.
Acta neuropathologica 142(5), 841-857 () [10.1007/s00401-021-02354-8]  GO BibTeX | EndNote: XML, Text | RIS

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The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets.
Cancer discovery 11(11), 2764-2779 () [10.1158/2159-8290.CD-21-0094]  GO BibTeX | EndNote: XML, Text | RIS

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Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.
Acta neuropathologica 142(5), 827-839 () [10.1007/s00401-021-02356-6]  GO BibTeX | EndNote: XML, Text | RIS

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Intimal sarcomas and undifferentiated cardiac sarcomas carry mutually exclusive MDM2, MDM4, and CDK6 amplifications and share a common DNA methylation signature.
Modern pathology 34(12), 2122-2129 () [10.1038/s41379-021-00874-y]  GO BibTeX | EndNote: XML, Text | RIS

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Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion-positive supratentorial ependymomas.
Cancer discovery 11(9), 2230-2247 () [10.1158/2159-8290.CD-20-0963]  GO BibTeX | EndNote: XML, Text | RIS

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Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1.
Acta neuropathologica 142(1), 179-189 () [10.1007/s00401-021-02302-6]  GO BibTeX | EndNote: XML, Text | RIS

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Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma
Journal of clinical oncology 39(7), 807 - 821 () [10.1200/JCO.20.01359]  GO BibTeX | EndNote: XML, Text | RIS

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Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup.
Modern pathology 34(8), 1558-1569 () [10.1038/s41379-021-00804-y]  GO BibTeX | EndNote: XML, Text | RIS

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NTRK Alterations in Pediatric High-Risk Malignancies Identified Through European Clinical Sequencing Programs Constitute Promising Drug Targets
JCO precision oncology 5, 450 - 454 () [10.1200/PO.20.00417]  GO BibTeX | EndNote: XML, Text | RIS

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Heterozygote PALB2 Mutation in einem Jungen mit ALL und metastasierten Ewing Sarkom.
Klinische Pa?diatrie 233(3), 141-144 () [10.1055/a-1404-3243]  GO BibTeX | EndNote: XML, Text | RIS

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The age of adult pilocytic astrocytoma cells.
Oncogene 40(16), 2830-2841 () [10.1038/s41388-021-01738-0]  GO BibTeX | EndNote: XML, Text | RIS

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Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Nature Communications 12(1), 1269 () [10.1038/s41467-021-21247-8]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study.
Acta neuropathologica 141(5), 771-785 () [10.1007/s00401-021-02284-5]  GO BibTeX | EndNote: XML, Text | RIS

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Integrated molecular analysis of adult Sonic Hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator.
Neuro-Oncology 23(9), 1576-1585 () [10.1093/neuonc/noab031]  GO BibTeX | EndNote: XML, Text | RIS

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Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1).
Acta neuropathologica 141(4), 605-617 () [10.1007/s00401-021-02276-5.]  GO BibTeX | EndNote: XML, Text | RIS

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H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model.
Cancer cell 39(3), 407-422.e13 () [10.1016/j.ccell.2021.01.005]  GO BibTeX | EndNote: XML, Text | RIS

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Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation.
Acta Neuropathologica Communications 9(1), 20 () [10.1186/s40478-021-01118-5]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Sarcoma classification by DNA methylation profiling.
Nature Communications 12(1), 498 () [10.1038/s41467-020-20603-4]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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A case series of Diffuse Glioneuronal Tumours with Oligodendroglioma-like features and Nuclear Clusters (DGONC).
Neuropathology & applied neurobiology 47(3), 464-467 () [10.1111/nan.12680]  GO BibTeX | EndNote: XML, Text | RIS

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Accurate calling of KIAA1549-BRAF fusions from DNA of human brain tumours using methylation array-based copy number and gene panel sequencing data.
Neuropathology & applied neurobiology 47(3), 406-414 () [10.1111/nan.12683]  GO BibTeX | EndNote: XML, Text | RIS

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Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1
Acta neuropathologica 141(2), 281-290 () [10.1007/s00401-020-02247-2]  GO BibTeX | EndNote: XML, Text | RIS

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Super enhancers define regulatory subtypes and cell identity in neuroblastoma
Nature cancer 2, 114?128 () [10.1038/s43018-020-00145-w]  GO BibTeX | EndNote: XML, Text | RIS

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Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
Acta neuropathologica 141(1), 85-100 () [10.1007/s00401-020-02243-6]  GO BibTeX | EndNote: XML, Text | RIS

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A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR.
Neuro-Oncology 23(1), 34-43 () [10.1093/neuonc/noaa251]  GO BibTeX | EndNote: XML, Text | RIS

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