Radiation therapy research is one of the most important focal points at the German Cancer Research Center (DKFZ). The work of the medical physicists is coming to fruition: the Center and Siemens Medical Solutions recently signed a cooperative as well as licensing agreement for software to be used for the planning of particle therapy with protons.
While Siemens receives the exclusive right of use for software and calculation methods for accurately planning particle therapy sessions with protons, the company reciprocates by supporting research positions for a period of three years. Additionally, the Institute benefits from revenues through the sale of software for therapy planning. DKFZ provides the required knowledge, works closely with Siemens Medical Solutions on product development, and then takes over clinical testing and further development of the planning programs.
In particle therapy, protons or carbon ions are brought to a very high speed with an accelerator system and accurately targeted at the tumor. The particles cause irreparable damage to the tumor cells. Through highly accurate computations and control, tumors of complex shape can be irradiated with millimeter precision, sparing the surrounding healthy tissue.
Important components of the licensing agreement concluded between the DKFZ Office of Technology Transfer and Siemens include the planning program for tumors in the brain and the body (“KonRad2“) and for eye tumors (“OCTOPUS“), which were developed to a large extent in the Department of Medical Physics for Radiation Therapy under the direction of Professor Wolfgang Schlegel. The programs enable the required radiation techniques and optimum dose to be calculated quickly based on CT and MRI images.
“This cooperation with Siemens will be another great milestone in the development of particle therapy," stated Schlegel. The new products will be used at the University Clinic in Heidelberg once the heavy ion therapy (HIT) system is completed. “Siemens will implement the technologies developed within the framework of the cooperative agreement in standard solutions for particle therapy, making them available to cancer patients worldwide," said Walter Folberth, Senior Vice President of Particle Therapy at Siemens Medical Solutions.
About DKFZ
With more than 3,000 employees, the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) is Germany’s largest biomedical research institute. DKFZ scientists identify cancer risk factors, investigate how cancer progresses and develop new cancer prevention strategies. They are also developing new methods to diagnose tumors more precisely and treat cancer patients more successfully. The DKFZ's Cancer Information Service (KID) provides patients, interested citizens and experts with individual answers to questions relating to cancer.
To transfer promising approaches from cancer research to the clinic and thus improve the prognosis of cancer patients, the DKFZ cooperates with excellent research institutions and university hospitals throughout Germany:
- National Center for Tumor Diseases (NCT, 6 sites)
- German Cancer Consortium (DKTK, 8 sites)
- Hopp Children's Cancer Center (KiTZ) Heidelberg
- Helmholtz Institute for Translational Oncology (HI-TRON Mainz) - A Helmholtz Institute of the DKFZ
- DKFZ-Hector Cancer Institute at the University Medical Center Mannheim
- National Cancer Prevention Center (jointly with German Cancer Aid)
The DKFZ is 90 percent financed by the Federal Ministry of Education and Research and 10 percent by the state of Baden-Württemberg. The DKFZ is a member of the Helmholtz Association of German Research Centers.