Link to page: Biomarkers for a long life
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Biomarkers for a long life

Epidemiologist Bernard Srour from the German Cancer Research Center receives one of the prizes for young scientists awarded annually by the Fondation Bettencourt Schueller. The young scientist investigates how lifestyle factors and metabolic markers can be used to predict disease risks and also life expectancy.

Link to page: Twelve "highly cited researchers" at DKFZ again in 2020
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Twelve "highly cited researchers" at DKFZ again in 2020

In 2020, twelve scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have again made it to the top: They are among the leading one percent of the world's highly cited researchers in their respective fields. This means that scientists whose work is cited particularly frequently by their peers are considered to be highly recognized and important in their field. The citation frequency is therefore one of the most important measurements for classifying the influence and performance of individual researchers.

Link to page: Biosafety at the DKFZ
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Biosafety at the DKFZ

Daily work routine of our more than 1,300 scientists at the DKFZ for the most part takes place in laboratories with different safety levels. Biological safety levels (at DKFZ: BSL1-BSL3) are based on the risk classification of the biological (or biomedical) work carried out. Each laboratory is designed around the safety level of its research, including the laboratory equipment, the specific working practices, and the typical protective equipment worn.

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Link to page: How Molecular Chaperones Dissolve Protein Aggregates Linked To Parkinson’s Disease
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How Molecular Chaperones Dissolve Protein Aggregates Linked To Parkinson’s Disease

In many neurodegenerative diseases like Parkinson's, protein aggregates form in the brain and are assumed to contribute to neuronal cell death. Yet there exists a cellular defense mechanism that counteracts these aggregates, known as amyloid fibrils, and can even dissolve fibrils already formed. This defense mechanism is based on the activity of molecular chaperones, i.e. protein folding helpers, of the heat shock protein 70 family (Hsp70). Molecular biologists from Heidelberg University and the German Cancer Research Center investigated how the Hsp70 system disaggregates amyloid fibrils of the Parkinson-specific protein α-synuclein in a test tube. The research team led by Bernd Bukau expects their results to provide new insights into how Parkinson's disease develops and what might be done to influence it. The results were published in two articles in the journal "Nature".

Link to page: Apply now for the International PhD Program at the DKFZ!
Deadline 15 December 2020

Apply now for the International PhD Program at the DKFZ!

Are you looking for excellent research opportunities for your PhD studies at the forefront of basic, epidemiological, computational or translational cancer research? Apply now!

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Link to page: Preventing diabetes means preventing cancer
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Preventing diabetes means preventing cancer

On the occasion of World Diabetes Day on November 14, the German Cancer Research Center (DKFZ) is providing information about the links between cancer and diabetes – and why a healthy lifestyle can reduce the risk for both of these serious diseases at the same time.

Link to page: Sharing algorithms instead of data
Joint Imaging Platform

Sharing algorithms instead of data

The new Joint Imaging Platform – JIP for short – is a flexible, decentralized analysis platform for medical images. The JIP was initially developed for the German Cancer Consortium (DKTK) sites. It is designed to facilitate cross-institutional imaging projects and to help meet the technical and legal challenges associated with the joint use of imaging data. What is special about the platform developed at the German Cancer Research Center (DKFZ) is that all imaging data remain at the original institution and only the analysis algorithms are shared.

Link to page: Which treatment is best for childhood brain tumors? Global trial receives funding of EUR 2.2m
Hopp Children’s Cancer Center Heidelberg

Which treatment is best for childhood brain tumors? Global trial receives funding of EUR 2.2m

The German Childhood Cancer Foundation (Deutsche Kinderkrebsstiftung, DKS) is providing EUR 2.2m to fund the first phase III clinical trial to investigate the best treatment options for certain types of childhood brain cancer with a chronic course. Initiated by the Hopp Children's Cancer Center Heidelberg (KiTZ), the trial will compare two standard chemotherapy treatments and a targeted therapy to establish which is the most effective and well tolerated as a standard therapy for young patients worldwide.

Link to page: Promising therapeutic approach against COPD
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Promising therapeutic approach against COPD

Chronic obstructive pulmonary disease (COPD) is one of the most common and deadliest diseases worldwide. Until today, COPD is not curable. Researchers at Helmholtz Zentrum München and at the German Cancer Research Center (DKFZ) have now succeeded in curing COPD in mice exposed to chronic cigarette smoke. Their goal is to test the novel therapeutic approach in human clinical trials over the next few years.

Cancer in the EU

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