CAYA Cancer Survivorship Research

  • Epidemiology, Public Health, Prevention and Survivorship
Eine lächelnde Frau mit lockigem, braunem Haar steht vor einer Steinmauer. Sie trägt einen grauen Cardigan über einem schwarzen Oberteil.

Dr. Cécile Ronckers

Head of Division

The division aims to generate methodologically sound evidence on the consequences of an early-life cancer diagnosis and treatment, to improve understanding of late effects, to study potential novel avenues for late effects prevention and care, and to contribute to translation and implementation of new research findings into well-coordinated and adequately funded survivorship care and support services, in multi-disciplinary networks of scientists, care providers, and patient representatives.

Logo DKFZ

The newly founded Division of CAYA (Children, Adolescents and Young Adults) Cancer Survivorship Research is led by Dr Cécile M. Ronckers. The Division is associated with the National Cancer Prevention Center and the Hopp Children’s Cancer Center Heidelberg.

Treatment for cancer in early life, including Children and AYAs (adolescents and young adults), can affect many different aspects of growing up and the later course of life. 

The work of the Division includes national and international observational research into somatic and other late effects among long-term survivors of CAYA cancer, building on existing and new collaborations, and capitalizing on innovative cross-discipline research opportunities at DKFZ, the Heidelberg campus, and beyond. 

This includes classic retrospective studies addressing impact of cancer treatment across the full life-span as well as prospective approaches to study effects of new treatments. A data-infrastructure/registry is envisioned to support integration of clinical, epidemiological, molecular, and future intervention research. Moreover, the division supports the set-up and gradual expansion of survivorship care structures for pediatric and AYA cancer survivors, also involving scientific evaluation and addressing policy aspects. 

In line with previous work, and where feasible, our work is guided by concepts of international standardization and harmonization. 

With regard to somatic late effects, long-standing research lines on subsequent tumors and on late effects of early-life medical radiation exposures (diagnostic and therapeutic) will be further pursued. 

The Division is financially supported by the Dietmar Hopp Foundation.

Team

  • Eine lächelnde Frau mit lockigem, braunem Haar steht vor einer Steinmauer. Sie trägt einen grauen Cardigan über einem schwarzen Oberteil.

    Dr. Cécile Ronckers

    Head of Division

  • Foto Julian Frick

    Julien Frick

Selected Publications

2025 - J Clin Oncol. 2025 Nov;43(31):3403-3421
2026 - EJC Ped Oncol (In Press)

Characterising childhood cancer survivors in Germany: A retrospective observational study on demographic, clinical, and healthcare utilization patterns

2023 - Nat Med. 2023 Sep 11;29(9):2268–77
2021 - J Clin Oncol . 2021 Sep 20;39(27):3012-3021
2019 - JAMA Oncology
2005 - Lancet 2005;365:2014-23

Second primary thyroid cancer after a first childhood malignancy: A report from the Childhood Cancer Survivor Study

Get in touch with us

Eine lächelnde Frau mit lockigem, braunem Haar steht vor einer Steinmauer. Sie trägt einen grauen Cardigan über einem schwarzen Oberteil.

Dr. Cécile Ronckers

Abteilungsleiterin
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